University of Groningen Human and rat organ slices de
... rently available. The ease of preparation (which is species independent) and scaling to in vivo (based on total organ weight) make the tissues slice technique a valuable in vitro tool for relatively short time incubations. The last interesting aspect of tissue slices that we would like to address at ...
... rently available. The ease of preparation (which is species independent) and scaling to in vivo (based on total organ weight) make the tissues slice technique a valuable in vitro tool for relatively short time incubations. The last interesting aspect of tissue slices that we would like to address at ...
A review of MRI findings in schizophrenia
... setting the stage for the development of the symptoms of schizophrenia. Or there may be additional factors, such as stress or neurotoxicity, that occur during adolescence or early adulthood and are necessary for the development of schizophrenia, and may be associated with neurodegenerative changes. ...
... setting the stage for the development of the symptoms of schizophrenia. Or there may be additional factors, such as stress or neurotoxicity, that occur during adolescence or early adulthood and are necessary for the development of schizophrenia, and may be associated with neurodegenerative changes. ...
Angiotensin-Converting Enzyme Inhibitor-Induced
... cough remains an unresolved issue, new developments since the publication of the first American College of Chest Physician consensus panel report include studies implicating the bradykinin receptor as relevant to ACE inhibitor function as well as the cough associated with these medications. Several ...
... cough remains an unresolved issue, new developments since the publication of the first American College of Chest Physician consensus panel report include studies implicating the bradykinin receptor as relevant to ACE inhibitor function as well as the cough associated with these medications. Several ...
Projections of auditory cortex to the medial geniculate body of the cat
... without a precise analogue in the visual thalamus (Stone, 1983). Therefore, it is pertinent to ask how many patterns of CT input exist within and between modalities. A second goal is to reexamine the auditory CT system with regard to the several (more than 10) regions now recognized as auditory cort ...
... without a precise analogue in the visual thalamus (Stone, 1983). Therefore, it is pertinent to ask how many patterns of CT input exist within and between modalities. A second goal is to reexamine the auditory CT system with regard to the several (more than 10) regions now recognized as auditory cort ...
Opioid painkillers compared
... nervous system injury or problems. Chronic pain is often defined another way as well: as any pain that lasts longer than three to six months. Thus, acute pain can become chronic just by virtue of how long it lasts. Chronic pain is common among people who have osteoarthritis, rheumatoid arthritis, fi ...
... nervous system injury or problems. Chronic pain is often defined another way as well: as any pain that lasts longer than three to six months. Thus, acute pain can become chronic just by virtue of how long it lasts. Chronic pain is common among people who have osteoarthritis, rheumatoid arthritis, fi ...
Antifungal Activity of Amiodarone Is Mediated by Disruption of
... Courchesne and Ozturk (2). Paradoxically, excessive or unregulated levels of calcium in the cytoplasm also lead to cell death and are implicated in the cytotoxicity of several drugs (8) as well as fungal toxins (9, 10). To better understand the role of calcium in AMD toxicity, it is important to dis ...
... Courchesne and Ozturk (2). Paradoxically, excessive or unregulated levels of calcium in the cytoplasm also lead to cell death and are implicated in the cytotoxicity of several drugs (8) as well as fungal toxins (9, 10). To better understand the role of calcium in AMD toxicity, it is important to dis ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
... coughed so hard that the muscles in his chest are hurting. He is unsteady on his feet and slightly confused. Which drug would be the best choice for this patient’s cough? A. benzonatate (Tessalon Perles) capsules B. dextromethorphan (Robitussin-DM) oral solution C. codeine cough syrup D. guaifenesin ...
... coughed so hard that the muscles in his chest are hurting. He is unsteady on his feet and slightly confused. Which drug would be the best choice for this patient’s cough? A. benzonatate (Tessalon Perles) capsules B. dextromethorphan (Robitussin-DM) oral solution C. codeine cough syrup D. guaifenesin ...
Drug-induced oral lichenoid reactions. A literature review
... these lesions are described according to the causal factor involved, including alterations resulting from direct contact with dental restoration materials, drug-related lesions, and lesions associated to graft-versus-host disease. Drug-induced oral lichenoid reactions or oral lichenoid lesions were ...
... these lesions are described according to the causal factor involved, including alterations resulting from direct contact with dental restoration materials, drug-related lesions, and lesions associated to graft-versus-host disease. Drug-induced oral lichenoid reactions or oral lichenoid lesions were ...
Interventional Spine and Pain Procedures in Patients - cmp
... spectrum than those for regional anesthesia, reflecting diverse targets and goals. When surveyed, interventional pain and spine physicians attending the American Society of Regional Anesthesia and Pain Medicine (ASRA) 11th Annual Pain Medicine Meeting exhorted that existing ASRA guidelines for regio ...
... spectrum than those for regional anesthesia, reflecting diverse targets and goals. When surveyed, interventional pain and spine physicians attending the American Society of Regional Anesthesia and Pain Medicine (ASRA) 11th Annual Pain Medicine Meeting exhorted that existing ASRA guidelines for regio ...
Ethanol Reversal of Tolerance to the Respiratory Depressant Effects
... decrease in minute volume induced by morphine is due to an action on respiratory rate generation or on chemoreflexes. Mice did not exhibit ribcage muscle stiffness, which would reduce tidal volume. As can be seen in Figure 1c, all mice tested responded to morphine with a decrease in respiration, we ...
... decrease in minute volume induced by morphine is due to an action on respiratory rate generation or on chemoreflexes. Mice did not exhibit ribcage muscle stiffness, which would reduce tidal volume. As can be seen in Figure 1c, all mice tested responded to morphine with a decrease in respiration, we ...
GINKGO BILOBA: A Cognitive Enhancer?
... design in which the treatment is administered after training, together with demonstrations of time-dependent effects on memory, would address this issue. When treatments are administered before training, in either chronic or single-treatment experiments, improvements on measures of learning and mem ...
... design in which the treatment is administered after training, together with demonstrations of time-dependent effects on memory, would address this issue. When treatments are administered before training, in either chronic or single-treatment experiments, improvements on measures of learning and mem ...
Abstract of “Primate frontal eye fields mediate spatial attention in
... functionally different types of neurons have been identified in FEF. Movement neurons begin to fire approximately 50ms before the initiation of a saccadic eye movement (Bruce and Goldberg, 1985; Thompson et al., 1996). These neurons are thought to influence eye movements through projections to the s ...
... functionally different types of neurons have been identified in FEF. Movement neurons begin to fire approximately 50ms before the initiation of a saccadic eye movement (Bruce and Goldberg, 1985; Thompson et al., 1996). These neurons are thought to influence eye movements through projections to the s ...
Review of cough and cold medicines in children
... been in use for at least 40 years. Indications for the uses of these drugs were accepted at much lower levels of evidence than would now be required, and there is no comprehensive review system for ‘grandfathered’ uses of drugs. Use in children has usually been extrapolated from adult practice with ...
... been in use for at least 40 years. Indications for the uses of these drugs were accepted at much lower levels of evidence than would now be required, and there is no comprehensive review system for ‘grandfathered’ uses of drugs. Use in children has usually been extrapolated from adult practice with ...
Current status and future potential.
... use of marijuana was associated with cognitive impairment of “executive functions” such as learning of lists, perseveration, and attention. In certain medical applications such as terminal cancer patients, such impairment may be less of a concern than in the daily functioning of high school and coll ...
... use of marijuana was associated with cognitive impairment of “executive functions” such as learning of lists, perseveration, and attention. In certain medical applications such as terminal cancer patients, such impairment may be less of a concern than in the daily functioning of high school and coll ...
Color responses of the human lateral geniculate nucleus: selective
... L-, M- and S-cone types normalized with respect to the white background (i.e. cone contrast). Stimulus chromaticity is given by the vector direction and contrast by vector length within the cone contrast space. Three cardinal stimuli (RG, BY and Ach) were determined within this space to isolate each ...
... L-, M- and S-cone types normalized with respect to the white background (i.e. cone contrast). Stimulus chromaticity is given by the vector direction and contrast by vector length within the cone contrast space. Three cardinal stimuli (RG, BY and Ach) were determined within this space to isolate each ...
Changes of Synaptic Density in the Primary Visual Cortex of the
... mm* ofcortical tissue, on which 289,433 synaptic contacts were marked, counted, measured, and classified. Counting procedure. The neuropil is commonly considered as the space occupied by small neuronal and glial cell processes (Peters et al., 1976). We adopted this definition and, therefore, exclude ...
... mm* ofcortical tissue, on which 289,433 synaptic contacts were marked, counted, measured, and classified. Counting procedure. The neuropil is commonly considered as the space occupied by small neuronal and glial cell processes (Peters et al., 1976). We adopted this definition and, therefore, exclude ...
Quantitative analysis of APP axonal transport in neurons: role of
... for the JNK signaling cascade (Weston and Davis, 2007), JIP1 has been independently identified as a kinesin light chain (KLC)–binding protein (Verhey et al., 2001; Inomata et al., 2003; Matsuda et al., 2003). Recently JIP1 was found to also associate with kinesin heavy chain (KHC; Fu and Holzbaur, 2 ...
... for the JNK signaling cascade (Weston and Davis, 2007), JIP1 has been independently identified as a kinesin light chain (KLC)–binding protein (Verhey et al., 2001; Inomata et al., 2003; Matsuda et al., 2003). Recently JIP1 was found to also associate with kinesin heavy chain (KHC; Fu and Holzbaur, 2 ...
Frequently Asked Questions
... Withdrawal is not healthy for a developing fetus but having a mother who is not getting enough oxygen or dying is far worse. Just be sure she really needs it (sternal rub) and call 911. What if my kids (or small children in area where Naloxone rescue kit is kept) find and use the Naloxone can it hur ...
... Withdrawal is not healthy for a developing fetus but having a mother who is not getting enough oxygen or dying is far worse. Just be sure she really needs it (sternal rub) and call 911. What if my kids (or small children in area where Naloxone rescue kit is kept) find and use the Naloxone can it hur ...
Neural Stem Cells and Cellular Therapy
... standard concentration used to assess neurogenesis (50-100 mg/kg body weight in rodents, intraperitoneal injection) may not label all the dividing cells (Taupin, 2007), whereas another study reports that it does (Burns and Kuan, 2005). Further systematic studies on BrdU labeling in the CNS are thus ...
... standard concentration used to assess neurogenesis (50-100 mg/kg body weight in rodents, intraperitoneal injection) may not label all the dividing cells (Taupin, 2007), whereas another study reports that it does (Burns and Kuan, 2005). Further systematic studies on BrdU labeling in the CNS are thus ...
Full Text Article
... measures could be taken for their prevention in future. These reports should be circulated widely so that the regulatory authorities can take necessary steps for modifying the drug labels, package inserts, issue warnings or for reconsideration of marketing approval. There are several methods of ADR ...
... measures could be taken for their prevention in future. These reports should be circulated widely so that the regulatory authorities can take necessary steps for modifying the drug labels, package inserts, issue warnings or for reconsideration of marketing approval. There are several methods of ADR ...
Neuron 2013 Bartolini
... Neurogliaform cells constitute a fourth large group of neocortical interneurons (Armstrong et al., 2012). They have a very characteristic morphology, with highly branched short dendrites and a defining dense local axonal plexus. Neurogliaform cells have a late-spiking firing pattern, and many expres ...
... Neurogliaform cells constitute a fourth large group of neocortical interneurons (Armstrong et al., 2012). They have a very characteristic morphology, with highly branched short dendrites and a defining dense local axonal plexus. Neurogliaform cells have a late-spiking firing pattern, and many expres ...
Studies on Variability in Olanzapine Disposition
... Schizophrenia and schizoaffective disorders are chronic conditions with a significant impact on many functions. Positive, negative, cognitive and motor symptoms appear in different degrees and constellations. Antipsychotics are of fundamental importance to reduce symptoms. However, insufficient clin ...
... Schizophrenia and schizoaffective disorders are chronic conditions with a significant impact on many functions. Positive, negative, cognitive and motor symptoms appear in different degrees and constellations. Antipsychotics are of fundamental importance to reduce symptoms. However, insufficient clin ...
THE AMYGDALA AND REWARD
... cortex reflect both the probability and quantity of expected reward for a visuomotor response. There is similar evidence for the orbital frontal cortex30–34. In the more purely sensory domain, Jagadeesh et al.35 showed that responses of neurons of the inferotemporal cortex to objects were modulated ...
... cortex reflect both the probability and quantity of expected reward for a visuomotor response. There is similar evidence for the orbital frontal cortex30–34. In the more purely sensory domain, Jagadeesh et al.35 showed that responses of neurons of the inferotemporal cortex to objects were modulated ...
The Placebo Effect: A Psychosocial and Neurobiological Review
... factor in deciding the difference between a new treatment and revealing a sham drug (Kleijnen, de Craen, van Everdingen and Krol, 1994). Alternatively, the placebo effect can be a means of ...
... factor in deciding the difference between a new treatment and revealing a sham drug (Kleijnen, de Craen, van Everdingen and Krol, 1994). Alternatively, the placebo effect can be a means of ...