Molecular and functional analysis of Drosophila single
... 1567-133X/$ - see front matter Ó 2011 Elsevier B.V. All rights reserved. ...
... 1567-133X/$ - see front matter Ó 2011 Elsevier B.V. All rights reserved. ...
Stereotyped connectivity and computations in higher
... In the first brain relay of the olfactory system, odors are encoded by combinations of glomeruli, but it is not known how glomerular signals are ultimately integrated. In Drosophila melanogaster, the majority of glomerular projections target the lateral horn. Here we show that lateral horn neurons ( ...
... In the first brain relay of the olfactory system, odors are encoded by combinations of glomeruli, but it is not known how glomerular signals are ultimately integrated. In Drosophila melanogaster, the majority of glomerular projections target the lateral horn. Here we show that lateral horn neurons ( ...
On the Biological Plausibility of Grandmother Cells
... much of the relevant neuroscience data. Although this article is largely directed to cognitive psychologists, I hope the article is of some relevance to neuroscientists as well. Despite the widespread rejection of grandmother cells in neuroscience literature, there is now a large body of evidence hi ...
... much of the relevant neuroscience data. Although this article is largely directed to cognitive psychologists, I hope the article is of some relevance to neuroscientists as well. Despite the widespread rejection of grandmother cells in neuroscience literature, there is now a large body of evidence hi ...
Mechanisms Underlying the Cardioinhibitory and Pressor
... (28). We have previously shown that activation of FTG neurons increases systemic arterial blood pressure (SAP) and decreases heart rate (HR) (28). However, the neural mechanisms mediating these cardiovascular responses were not known. Various nuclei in the medulla oblongata are essential for regulat ...
... (28). We have previously shown that activation of FTG neurons increases systemic arterial blood pressure (SAP) and decreases heart rate (HR) (28). However, the neural mechanisms mediating these cardiovascular responses were not known. Various nuclei in the medulla oblongata are essential for regulat ...
resumo_pertes_mecani..
... An action potential represents a transient change in the resting membrane potential of a neuron. Following an action potential is a brief period of hyperpolarization during which the resting membrane potential of most nerve cells becomes notably negative. This occurs because of inactivation of Na ch ...
... An action potential represents a transient change in the resting membrane potential of a neuron. Following an action potential is a brief period of hyperpolarization during which the resting membrane potential of most nerve cells becomes notably negative. This occurs because of inactivation of Na ch ...
Increased Expression of Neuronal Nitric Oxide Synthase (NOS) in
... Increased numbers of NOS-IR in DRG cells were not significantly different 2, 3, or 4 weeks after axotomy. Thus, the data from all survival periods were treated as a single group. NADPH-d activity in DRG was not quantified after axotomy due to the large numbers of these cells and the variations in st ...
... Increased numbers of NOS-IR in DRG cells were not significantly different 2, 3, or 4 weeks after axotomy. Thus, the data from all survival periods were treated as a single group. NADPH-d activity in DRG was not quantified after axotomy due to the large numbers of these cells and the variations in st ...
Research Involving Investigational Drugs
... A. When human subjects research involves the use of drugs or biological products, FDA regulations apply. Investigators must provide sufficient information about the drug or biologic for the IRB to evaluate its associated risks and benefits, including the FDA approval status of the product (i.e., app ...
... A. When human subjects research involves the use of drugs or biological products, FDA regulations apply. Investigators must provide sufficient information about the drug or biologic for the IRB to evaluate its associated risks and benefits, including the FDA approval status of the product (i.e., app ...
Imaging modalities shed light on intracranial cysts
... Glioblastoma multiforme is a common primary brain tumor that typically occurs in the cerebral hemispheric white matter. Lesions are poorly delineated diffusely infiltrating partially necrotic masses. A thick irregular rind of tissue is seen around a necrotic core on imaging. Signal intensity is vari ...
... Glioblastoma multiforme is a common primary brain tumor that typically occurs in the cerebral hemispheric white matter. Lesions are poorly delineated diffusely infiltrating partially necrotic masses. A thick irregular rind of tissue is seen around a necrotic core on imaging. Signal intensity is vari ...
The impact of polypharmacology on chemical biology Albert Antolín Hernández
... There is now ample evidence that drugs have biologically relevant interactions with more than one protein, a behavior that is commonly referred to as polypharmacology. This finding is starting to have a true impact on the drug discovery process, transforming it into a more holistic endeavor. In cont ...
... There is now ample evidence that drugs have biologically relevant interactions with more than one protein, a behavior that is commonly referred to as polypharmacology. This finding is starting to have a true impact on the drug discovery process, transforming it into a more holistic endeavor. In cont ...
Mechanisms underlying working memory for novel information
... studies of working memory did not report activity within parahippocampal regions such as perirhinal or entorhinal cortex, although these areas had previously been shown to be necessary for DNMS and DMS tasks in monkeys [18,19,23]. The non-human primate lesion studies motivated an fMRI study by Stern ...
... studies of working memory did not report activity within parahippocampal regions such as perirhinal or entorhinal cortex, although these areas had previously been shown to be necessary for DNMS and DMS tasks in monkeys [18,19,23]. The non-human primate lesion studies motivated an fMRI study by Stern ...
Alcohol and Other Drugs Alcohol and Other Drugs
... regard to alcohol. This means that when the team is assembled to prepare for, attend and participate in an event, members are not allowed to drink alcohol or consume illicit or prohibited drugs. ...
... regard to alcohol. This means that when the team is assembled to prepare for, attend and participate in an event, members are not allowed to drink alcohol or consume illicit or prohibited drugs. ...
Advice to The Expert Advisory Committee on drugs on: LSD
... exacerbation of pre-existing psychiatric conditions. There have been instances recorded of LSD users suffering periods of psychotic episodes following use of LSD12. Early research about the risk of psychosis reported a rate of 0.8 per 1000 non-patient participants and a rate of 1.8 per 1000 patients ...
... exacerbation of pre-existing psychiatric conditions. There have been instances recorded of LSD users suffering periods of psychotic episodes following use of LSD12. Early research about the risk of psychosis reported a rate of 0.8 per 1000 non-patient participants and a rate of 1.8 per 1000 patients ...
GLOSSARY of Occupational Therapy Terminology
... Self-regulation: Nervous system’s ability to attain, maintain, and change levels of arousal or alertness. Sensory Diet: A term devised by Patricia Wilbarger in 1971 to describe a therapeutic method to maintain an optimal level of arousal (in the nervous system) by offering the right combination of s ...
... Self-regulation: Nervous system’s ability to attain, maintain, and change levels of arousal or alertness. Sensory Diet: A term devised by Patricia Wilbarger in 1971 to describe a therapeutic method to maintain an optimal level of arousal (in the nervous system) by offering the right combination of s ...
Genome-wide analysis of the bHLH gene family in
... compensate for cells lost after injury or disease. Therefore, to examine how neural precursors could be directed to repair CNS neurons in vivo, comparative approaches using animal models of regeneration will help us to gain insights into the basic mechanisms needed to reestablish nervous system func ...
... compensate for cells lost after injury or disease. Therefore, to examine how neural precursors could be directed to repair CNS neurons in vivo, comparative approaches using animal models of regeneration will help us to gain insights into the basic mechanisms needed to reestablish nervous system func ...
Question
... Clinical Pharmacy Specialist, Solid Organ Transplant Clinical Assistant Professor of Pharmacy MUSC Department of Pharmacy Services ...
... Clinical Pharmacy Specialist, Solid Organ Transplant Clinical Assistant Professor of Pharmacy MUSC Department of Pharmacy Services ...
Dr. Srivastava
... fungi preventing tomour growth Spolectin is an important chemical required by body for smooth joint movement Spolectin is also antihistaminic It is also analgesic and antipyretic Spolectin have been found 5 times more effective than aspirin Significant analgesic of noni in mice on hot plate was demo ...
... fungi preventing tomour growth Spolectin is an important chemical required by body for smooth joint movement Spolectin is also antihistaminic It is also analgesic and antipyretic Spolectin have been found 5 times more effective than aspirin Significant analgesic of noni in mice on hot plate was demo ...
2008 - SUNY Upstate Medical University
... eyes, patients should be copiously irrigated with the closest available irrigation solution, most commonly water or normal saline. In select circumstances, where the corrosive agent is not soluble in water or normal saline, such as in the case of phenol, high molecular weight poly ethylene glycol so ...
... eyes, patients should be copiously irrigated with the closest available irrigation solution, most commonly water or normal saline. In select circumstances, where the corrosive agent is not soluble in water or normal saline, such as in the case of phenol, high molecular weight poly ethylene glycol so ...
Basic Mechanisms Underlying Seizures and Epilepsy
... Hilar ectopic granule cells in a rat model of temporal lobe epilepsy. (A) Nissl-stained section showing the hippocampus in the transverse axis. The boxed area is shown in part B. (B) A section is stained with an antibody to Prox1, a specific marker of GC nuclei in the dentate gyrus. In the saline-tr ...
... Hilar ectopic granule cells in a rat model of temporal lobe epilepsy. (A) Nissl-stained section showing the hippocampus in the transverse axis. The boxed area is shown in part B. (B) A section is stained with an antibody to Prox1, a specific marker of GC nuclei in the dentate gyrus. In the saline-tr ...
Andrea Kádár
... central regulators of the hypothalamus-pituitary-thyroid (HPT) axis. These neurosecretory neurons are located in the hypothalamic paraventricular nucleus (PVN) and their axons terminate outside the blood-brain barrier (BBB) in the external zone of the median eminence (ME) where TRH is secreted to th ...
... central regulators of the hypothalamus-pituitary-thyroid (HPT) axis. These neurosecretory neurons are located in the hypothalamic paraventricular nucleus (PVN) and their axons terminate outside the blood-brain barrier (BBB) in the external zone of the median eminence (ME) where TRH is secreted to th ...
letter - Wall Street Journal
... The draft guidance poses multiple risks. First, it appears to be based on the premise that peer-reviewed reports provide accurate, validated information and that even if individual articles are biased, the published literature as a whole can provide balance. Regrettably, recent experience shows that ...
... The draft guidance poses multiple risks. First, it appears to be based on the premise that peer-reviewed reports provide accurate, validated information and that even if individual articles are biased, the published literature as a whole can provide balance. Regrettably, recent experience shows that ...
From blood–brain barrier to blood–brain interface: new
... early in the twentieth century for its ability to prevent the uncontrolled leakage of substances from the blood into the brain, the BBB has emerged as a complex, dynamic, adaptable interface that controls the exchange of substances between the central nervous system (CNS) and the blood (BOX 1). The ...
... early in the twentieth century for its ability to prevent the uncontrolled leakage of substances from the blood into the brain, the BBB has emerged as a complex, dynamic, adaptable interface that controls the exchange of substances between the central nervous system (CNS) and the blood (BOX 1). The ...
Neuronal and microglial cathepsins in aging and age
... neurons of cathepsin D-deficient mice, we noticed that these animals showed neurological phenotypes such as seizures and blindness near the terminal stage. The most striking feature found in the CNS was a profound storage of autophagosome/autolysosome-like bodies with part of the cytoplasm, granular ...
... neurons of cathepsin D-deficient mice, we noticed that these animals showed neurological phenotypes such as seizures and blindness near the terminal stage. The most striking feature found in the CNS was a profound storage of autophagosome/autolysosome-like bodies with part of the cytoplasm, granular ...
6Control Drug Delivery System
... ii) Distribution: It not only lowers the concentration of circulating drug but it also can be rate limiting in its equilibration with blood and extracellular fluid. The Vd and the ratio of drug in tissue to that of plasma at steady state is an important parameters to be considered in determining the ...
... ii) Distribution: It not only lowers the concentration of circulating drug but it also can be rate limiting in its equilibration with blood and extracellular fluid. The Vd and the ratio of drug in tissue to that of plasma at steady state is an important parameters to be considered in determining the ...
