Maternal Influenza Viral Infection Causes Schizophrenia
... Indeed, LSD effects were one of the earliest models of schizophrenia (Keeler, 1965), and are currently believed to model the symptoms that occur at the onset of this disorder (Geyer and Vollenweider, 2008). Preclinical findings in rodents have demonstrated that metabotropic glutamate receptor mGlu2/ ...
... Indeed, LSD effects were one of the earliest models of schizophrenia (Keeler, 1965), and are currently believed to model the symptoms that occur at the onset of this disorder (Geyer and Vollenweider, 2008). Preclinical findings in rodents have demonstrated that metabotropic glutamate receptor mGlu2/ ...
114. Anna - Weizmann Institute of Science
... 2002). Another important candidate is the monoclonal antibody pertuzumab, which inhibits heterodimerization of HER2 with EGFR and with HER3 (Agus et al., 2002). Another promising strategy might be to combine mAbs against the same receptor. Our previous studies revealed that HER2 comprises at least ...
... 2002). Another important candidate is the monoclonal antibody pertuzumab, which inhibits heterodimerization of HER2 with EGFR and with HER3 (Agus et al., 2002). Another promising strategy might be to combine mAbs against the same receptor. Our previous studies revealed that HER2 comprises at least ...
NIHbioKAM - Kurt A. Mossberg
... #2005-07, Moody Endowment; Improving physical and psychological health in individuals with brain injury and the frail elderly, 2005-06. The goal of this project was to explore the changes in physical and cognitive function as a result of high intensity physical training in patients recovering from T ...
... #2005-07, Moody Endowment; Improving physical and psychological health in individuals with brain injury and the frail elderly, 2005-06. The goal of this project was to explore the changes in physical and cognitive function as a result of high intensity physical training in patients recovering from T ...
Computing with Spiking Neuron Networks
... its detailed workings are the subject of interest in fields as diverse as the study of neurophysiology, consciousness, and of course artificial intelligence. Less grand in scope, and more focused on the functional detail, artificial neural networks attempt to capture the essential computations that ...
... its detailed workings are the subject of interest in fields as diverse as the study of neurophysiology, consciousness, and of course artificial intelligence. Less grand in scope, and more focused on the functional detail, artificial neural networks attempt to capture the essential computations that ...
Distribution of phosphorylated cyclic AMP response element binding
... in retinal ganglion cells (RGCs). The retinal neurons were labeled with microtubule-associated protein-2 (MAP-2) or THY1.1, the specific cellular makers for neurons and retinal ganglion cells, respectively. As shown in Figure 2A and 2B, the MAP-2 stained neuronal axons and cell bodies were present i ...
... in retinal ganglion cells (RGCs). The retinal neurons were labeled with microtubule-associated protein-2 (MAP-2) or THY1.1, the specific cellular makers for neurons and retinal ganglion cells, respectively. As shown in Figure 2A and 2B, the MAP-2 stained neuronal axons and cell bodies were present i ...
A thalamic reticular networking model of consciousness
... short-term change in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated excitatory postsynaptic current amplitudes in response to stimulation at non-gamma frequencies (less than 30 Hz), simulating background activity, but showed shortterm depression in such amplitudes ...
... short-term change in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated excitatory postsynaptic current amplitudes in response to stimulation at non-gamma frequencies (less than 30 Hz), simulating background activity, but showed shortterm depression in such amplitudes ...
Antibiotic distribution into the CNS
... Additional host factors such as meningeal inflammation* and age as well as physicochemical properties of drugs are also important ...
... Additional host factors such as meningeal inflammation* and age as well as physicochemical properties of drugs are also important ...
Anticholinergics for Overactive Bladder
... urine secondary to intra-abdominal pressure such as occurs with coughing, sneezing and exercise.9 • Anticholinergics (ACs) are useful drugs for treating OAB, however their use is limited by the side effects of dry mouth and constipation. ...
... urine secondary to intra-abdominal pressure such as occurs with coughing, sneezing and exercise.9 • Anticholinergics (ACs) are useful drugs for treating OAB, however their use is limited by the side effects of dry mouth and constipation. ...
Rapid Changes in Synaptic Vesicle Cytochemistry
... the vesicle membrane (reserpine). In addition, choline appears to play a competitive role because its presence during incubation in NE or after reloading results in decreased numbers of dense-cored vesicles. We conclude that the depolarization step preceding catecholamine incubation acts to empty th ...
... the vesicle membrane (reserpine). In addition, choline appears to play a competitive role because its presence during incubation in NE or after reloading results in decreased numbers of dense-cored vesicles. We conclude that the depolarization step preceding catecholamine incubation acts to empty th ...
Comprehensive Evaluation of the Child With Intellectual
... intellectual disabilities and their families.3–5 Although perhaps difficult to measure, this “healing touch” contributes to the general well-being of the family. “As physicians we have experience with other children who have the same disorder, access to management programs, knowledge of the prognosis ...
... intellectual disabilities and their families.3–5 Although perhaps difficult to measure, this “healing touch” contributes to the general well-being of the family. “As physicians we have experience with other children who have the same disorder, access to management programs, knowledge of the prognosis ...
ISOLATION AND IDENTIFICATION OF α-GLUCOSIDASE, α-AMYLASE AND LIPASE INHIBITORS
... to the control drug (Orlistat). The literature shows a variety of plant species used as antidiabetics in various traditional systems of medicines including species in the family Rutaceae [20], but few examples of assays with substances inhibiting enzymes that can promote the therapy of diabetes and ...
... to the control drug (Orlistat). The literature shows a variety of plant species used as antidiabetics in various traditional systems of medicines including species in the family Rutaceae [20], but few examples of assays with substances inhibiting enzymes that can promote the therapy of diabetes and ...
Amphetamines: An Update on Forensic Issues
... decision-making. Their voluntary use under these situations introduces both criminal and civil liability for the user. Their toxic effects, acting on organ systems including the heart and brain, can result in tissue damage, arrhythmia, tachycardia, and hypertension, any of which can be further exace ...
... decision-making. Their voluntary use under these situations introduces both criminal and civil liability for the user. Their toxic effects, acting on organ systems including the heart and brain, can result in tissue damage, arrhythmia, tachycardia, and hypertension, any of which can be further exace ...
Preparation and Evaluation of Minoxidil Gels
... The in vitro release data obtained was treated with Higuchi’s equation (Q=kt1/2) to understand the mechanism of drug release from the formulations. The data was plotted as cumulative percent released vs. square root of time. A close observation of the linear regression results reveals that minoxidil ...
... The in vitro release data obtained was treated with Higuchi’s equation (Q=kt1/2) to understand the mechanism of drug release from the formulations. The data was plotted as cumulative percent released vs. square root of time. A close observation of the linear regression results reveals that minoxidil ...
Rhythmic Spontaneous Activity in the Piriform Cortex
... olfactory bulb and other cortical and extracortical areas (for a review, see Neville and Haberly 2004). Deeper to the piriform cortex is the endopiriform nucleus, considered by some authors the fourth layer of this cortex because of their extensive reciprocal connections (O’Leary 1937; ValverdeGarci ...
... olfactory bulb and other cortical and extracortical areas (for a review, see Neville and Haberly 2004). Deeper to the piriform cortex is the endopiriform nucleus, considered by some authors the fourth layer of this cortex because of their extensive reciprocal connections (O’Leary 1937; ValverdeGarci ...
Hunger Modulates the Responses to Gustatory Stimuli
... Received 25 February 1988, revised 15 July 1988, accepted 18 July 1988 ...
... Received 25 February 1988, revised 15 July 1988, accepted 18 July 1988 ...
CHAPTER 5 Conclusions and general discussion (adapted, several protein names removed)
... The large fraction of blood-derived proteins in CSF – around 80% of the CSF proteome [27] – is one of the potential explanations for the limited overlap between the LC and CSF proteome. Another factor may be that not all brain-derived proteins identified in CSF will be present in a single specific b ...
... The large fraction of blood-derived proteins in CSF – around 80% of the CSF proteome [27] – is one of the potential explanations for the limited overlap between the LC and CSF proteome. Another factor may be that not all brain-derived proteins identified in CSF will be present in a single specific b ...
Rational Use and Interpretation of Urine Drug Testing in
... Other methods for drug screening. Analytical methods to screen for drugs in urine are not limited to antibody-based assays. Other analytical methods exist, including thin-layer chromatography, highpressure liquid chromatography, and gas chromatography [33]. These methods offer distinct advantages, p ...
... Other methods for drug screening. Analytical methods to screen for drugs in urine are not limited to antibody-based assays. Other analytical methods exist, including thin-layer chromatography, highpressure liquid chromatography, and gas chromatography [33]. These methods offer distinct advantages, p ...
IRSF-Rett-Syndrome-Fact-Sheet
... comprehensive non-profit organization dedicated to providing thorough and accurate information about Rett syndrome, offering informational and emotional family support, and stimulating research aimed at accelerating treatments and a cure for Rett syndrome and related disorders. IRSF has earned Chari ...
... comprehensive non-profit organization dedicated to providing thorough and accurate information about Rett syndrome, offering informational and emotional family support, and stimulating research aimed at accelerating treatments and a cure for Rett syndrome and related disorders. IRSF has earned Chari ...
Orbitofrontal Cortex and Human Drug Abuse: Functional Imaging
... anterior regions schematically would be important in decisionmaking processes, and posterior regions in the emotional and autonomic aspects of craving. Both regions could contribute to expectancy, which depends on the evaluation of the emotional valence of the stimulus. Along a transaxial plane, the ...
... anterior regions schematically would be important in decisionmaking processes, and posterior regions in the emotional and autonomic aspects of craving. Both regions could contribute to expectancy, which depends on the evaluation of the emotional valence of the stimulus. Along a transaxial plane, the ...
Sections 18 to 27
... WHO Model List of Essential Drugs (EDL) with rational and evidence where available 11th edition (Nov. 1999) ...
... WHO Model List of Essential Drugs (EDL) with rational and evidence where available 11th edition (Nov. 1999) ...
ANS: c, p. 42, F, LO=2.1, (1)
... c) regulating metabolic activity and serving as pain detectors d) monitoring neural transmission and releasing hormones in the brain ANS: a, pp. 43-44, C, LO=2.1, (3) % correct 59 a= 59 b= 4 c= 11 d= 22 r = .32 18. Two types of glial cells, called __________ and ___________, generate myelin. e) occi ...
... c) regulating metabolic activity and serving as pain detectors d) monitoring neural transmission and releasing hormones in the brain ANS: a, pp. 43-44, C, LO=2.1, (3) % correct 59 a= 59 b= 4 c= 11 d= 22 r = .32 18. Two types of glial cells, called __________ and ___________, generate myelin. e) occi ...
Okamoto Devel Neurbiol Review
... into dHb and vHb based on differences in cytoarchitecture (Braford and Northcutt, 1983; Kemali and Làzàr, 1985). The zebrafish dHb projects to the IPN (Aizawa et al., 2005; Gamse et al., 2005) and is thus analogous to the medial habenula of mammals [Fig. 3(A,B)]. Axonal tracing in live and fixed fish ...
... into dHb and vHb based on differences in cytoarchitecture (Braford and Northcutt, 1983; Kemali and Làzàr, 1985). The zebrafish dHb projects to the IPN (Aizawa et al., 2005; Gamse et al., 2005) and is thus analogous to the medial habenula of mammals [Fig. 3(A,B)]. Axonal tracing in live and fixed fish ...
Abuse of OTC Drugs
... The similarity in their mechanism of action accounts for the PCP-like behavioral effects produced by high doses of DXM. The metabolite, dextrorphan, has a higher affinity for the NMDA receptor than does the parent compound and is comparable to ketamine. DXM may cause a false-positive test result wit ...
... The similarity in their mechanism of action accounts for the PCP-like behavioral effects produced by high doses of DXM. The metabolite, dextrorphan, has a higher affinity for the NMDA receptor than does the parent compound and is comparable to ketamine. DXM may cause a false-positive test result wit ...
Unit4Jeopardy
... • ANSWER: I see images even when my eyes are closed, so the doctor has ordered a scan of this. • QUESTION: What is the occipital lobe? ...
... • ANSWER: I see images even when my eyes are closed, so the doctor has ordered a scan of this. • QUESTION: What is the occipital lobe? ...
relpax® utilization management criteria
... than 2 hours after the initial dose. The total daily dose should not exceed 80 mg. There is no evidence that a second dose of eletriptan is effective in patients who do not respond to a first dose of the drug for the same headache. NOTE: In patients who do not respond to the first dose of eletriptan ...
... than 2 hours after the initial dose. The total daily dose should not exceed 80 mg. There is no evidence that a second dose of eletriptan is effective in patients who do not respond to a first dose of the drug for the same headache. NOTE: In patients who do not respond to the first dose of eletriptan ...