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Nucleus Accumbensμ-Opioids Regulate Intake of a High
Nucleus Accumbensμ-Opioids Regulate Intake of a High

... wire stylets were placed in the guide cannulas to prevent occlusion. Coordinates for the aimed sites were as follows (in mm from bregma): nucleus accumbens (ACC): anteroposterior (AP) 1.4, mediolateral (ML) ⫾1.8, dorsoventral (DV) ⫺7.8; lateral hypothalamus (LH): AP ⫺2.8, ML ⫾1.8, DV ⫺8.7; dorsomedi ...
Depth Perception
Depth Perception

... Prazdny offered a specific laboratory test using a random-dot stereogram in which the background plane is transparent, and where two depths, one from low and one from high spatial frequencies, can be observed simultaneously. He concludes that patches of the visual field may be fused and then held "l ...
Enhancement of Conditioned Place Preference Response to
Enhancement of Conditioned Place Preference Response to

... In this study, we measured conditioned place preference (CPP) responses to cocaine following subchronic administration of the recreationally abused drug (6)-3,4-methylenedioxymethamphetamine (MDMA, ‘‘ecstasy’’) in male Sprague-Dawley rats. Animals were given either vehicle (1 ml/kg of distilled wate ...
100 Essential Drugs - University of Toledo
100 Essential Drugs - University of Toledo

... MOA: mechanism of action involves entry into the cells of the infectious organism where it is chemically reduced and products of reduction cause death by interacting with DNA and interfering with cell division I: amebic infections, DOC for trichomoniasis and giardiasis, Tx of Bacteroides fragilis, C ...
Yale Review of Undergraduate Research in
Yale Review of Undergraduate Research in

... shows a causative relationship; it heavily suggests that the underlying mechanisms of NREM might be involved in the consolidation of declarative memories. Sleep deprivation. Another way to study NREM sleep is through sleep deprivation, though this can be dif37 ...
Chapter 15 The Nervous System
Chapter 15 The Nervous System

... How do organs and other structures enable the nervous system to function? You smell a delicious aroma. You walk into the kitchen and see a bag of popcorn in the microwave. You hear some kernels still popping. Then you think to yourself, “Snack time!” Which body systems enabled you to smell, walk, se ...
Heart of Darkness - American Journal of Neuroradiology
Heart of Darkness - American Journal of Neuroradiology

... gions that began in Mesopotamia and adjacent territories, however, recognize evil in the form of Satan (Judaism ⫽ haSatan, Christianity ⫽ devil, and Islam ⫽ Shaitan). Satan was the chief of the fallen angels, that is, angels who were banished from Heaven and sent to earth to tempt man into committin ...
NETMORPH: A Framework for the Stochastic
NETMORPH: A Framework for the Stochastic

... changes in synaptic connectivity, as observed in brain diseases such as Alzheimer’s disease and autism, may arise from alterations in neuronal morphology (Belmonte and Bourgeron 2006; Scheff et al. 2007); and investigating the complex relationship between neuronal morphology and local and global pat ...
From spike frequency to free recall:
From spike frequency to free recall:

... In this model, the primary locus for encoding of associations was in region CA3 of the hippocampal formation. Two features of region CA3 make it particularly appealing as the locus for storage of episodic memory. 1.) the convergence of multimodal sensory information on this region means that strengt ...
Eps homology domain endosomal transport proteins differentially
Eps homology domain endosomal transport proteins differentially

... proteins of the endocytic machinery, EHD family proteins share a central coiled-coil and an N-terminal phosphate binding loop (P-loop) [3,5]. These proteins are products of gene duplication, are encoded on separate chromosomes, and have differential expression profiles in various tissues [3,4,6-8]. ...
PDF
PDF

... canis has been recognized only in vivo (Vercammen et al. 1966). Most dogs recovered from the acute stage of the disease are at risk of recurrence and may become a reservoir for tick-borne infections (Conrad et al., 1991). Although these therapeutic modalities are beneficial and seem to cure partiall ...
Transcranial Magnetic Stimulation: Decomposing the
Transcranial Magnetic Stimulation: Decomposing the

Chapter 2 NOTES - North Mac Schools
Chapter 2 NOTES - North Mac Schools

... Copyright © Houghton Mifflin Company. All rights reserved. ...
The Brain and Fatigue : New Opportunities for
The Brain and Fatigue : New Opportunities for

... complex phenomenon influenced by both events occurring in the periphery and the CNS (Meeusen and De Meirleir, 1995; Nybo and Secher, 2004). At the highest level, football players have been reported to cover distances in excess of 10km during competitive matches (Bangsbo et al., 1991). This activity ...
Rewardguided learning beyond dopamine in the nucleus
Rewardguided learning beyond dopamine in the nucleus

... which are more similar to Pavlovian responses in their relative insensitivity to changes in the instrumental contingency, but are also impervious to outcome devaluation because the outcome is not part of the representational structure controlling performance (cf. Dickinson, 1985; and below for furth ...
QA253_3_AntidepressMisc_final
QA253_3_AntidepressMisc_final

... were greater in hindmilk than in foremilk (23,24). Infant intake via milk was estimated as 8 micrograms/kg/day for mirtazapine and 3 micrograms/kg/day for the metabolite (24). In this study in 8 mother-infant pairs, it was calculated that infants would ingest an average 1.9% (0.7 – 3.1%) of the weig ...
Central nervous system effects of caffeine and adenosine on fatigue
Central nervous system effects of caffeine and adenosine on fatigue

... protocol. By allowing this small variation in treadmill speed, overall run time to fatigue was much more consistent at ⬃90 min. 284 • FEBRUARY 2003 • ...
DRUG ABSORPTION, DISTRIBUTION AND ELIMINATION
DRUG ABSORPTION, DISTRIBUTION AND ELIMINATION

... The body is exposed to a wide variety of foreign compounds, called xenobiotics. Exposure to some such compounds is unintentional (e.g., environmental or food substances), while others are deliberately used as drugs. The following discussion of drug biotransformation is applicable to all xenobiotics, ...
Raven Ch
Raven Ch

... B. Answer b is incorrect. Spatial summation describes the effect of multiple presynaptic cells firing almost simultaneously. The correct answer is a— C. Answer c is incorrect. Habituation occurs when the nervous system becomes accustomed to a signal and learns to ignore it (no response would be gene ...
Effects of different doses of venlafaxine on serotonin and
Effects of different doses of venlafaxine on serotonin and

... the day the baseline data were collected. The paroxetine group received 10 mg in the morning, the nefazodone group received 75 mg b.i.d., the desipramine group 25 mg b.i.d., the low-dose venlafaxine group 37.5 mg b.i.d., and the high-dose venlafaxine group 75 mg b.i.d. For the next 5 d, all subjects ...
ACTIN CYTOSKELETON REGULATION IN NEURONAL
ACTIN CYTOSKELETON REGULATION IN NEURONAL

... For instance, pioneer sensory axons growing from grasshopper explants lose their pathfinding capability upon cytochalasin treatment but still maintain their ability to grow (Bentley & Toroian-Raymond, 1986). Under these conditions sensory neuron growth cones are also devoid of filopodia, suggesting ...
Uppers, Downers, All Arounders, 7th Edition
Uppers, Downers, All Arounders, 7th Edition

... list for treatment follow through and enter treatment. C. HARM REDUCTION (pp. 8.15−8.16) Harm reduction focuses on techniques to minimize the personal and social problems associated with drug use rather than making abstinence the primary goal. Bleach distribution and needle-exchange efforts can redu ...
Singing in the Brain: Investigating the Role of Adult
Singing in the Brain: Investigating the Role of Adult

... Neurogenesis refers to the process of adding new neurons in the brain. It is typically a perinatal phenomenon. However, it can occur in very specific regions of the adult vertebrate brain, usually related to memory. The role of neurogenesis in memory is not yet clear. Some evidence suggests that neu ...
Chapter 13 - Martini
Chapter 13 - Martini

... – Carry sensory inputs into the CNS via the central processes of their axons. They begin at the general sensory receptors of the skin (somatic sensory) and internal organs (visceral sensory). – Are also known as afferent pathways. – Special sense will be covered in Chapter 17 ...
An Introduction to Medicinal Chemistry
An Introduction to Medicinal Chemistry

... There can be little doubt that alcohol is a drug and as such causes society more problems than all other drugs put together. One only has to study road accident statistics to appreciate that fact. It has been stated that if alcohol was discovered today, it would be restricted in exactly the same way ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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