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Module 10 - Neuronal Signalling
Module 10 - Neuronal Signalling

... characterizes the brain rhythms detected by electroencephalograms (EEGs). Any consideration of synaptic transmission must take into account the fact that the rate of synaptic transmission is often extremely high. Another example of the significance of timing concerns neuronal coincident detection, d ...
Words in the brain`s language
Words in the brain`s language

... a fully connected associative memory in which every processing unit is connected to every other one, it still appears to be an associative network well suited to allow for both local and between-area associative learning (Braitenberg & Schüz 1991; 1998; Fuster 1994; Palm 1982). If neurons in an asso ...
The Morphology of Physiologically Identified GABAergic Neurons in
The Morphology of Physiologically Identified GABAergic Neurons in

... anatomical connectivity, it quickly became evident that corticothalamic fibers, passing to a particular dorsal thalamic nucleus, and thalamocortical fibers emanating from that dorsal thalamic nucleus, give rise to terminations in the same part of the reticular nucleus as they pass through it. Moreov ...
rem sleep - Website Staff UI
rem sleep - Website Staff UI

... • The timing of and need for sleep (and wakefulness) are governed by the shifting balance of two intrinsic regulatory process: The circadian rhythm of alertness and sleepiness; and the homeostatic drive for NREM sleep. • The longer we are awake the greater our need for NREM Stage 3 sleep. The homoeo ...
Opiates Drug Information
Opiates Drug Information

... Morphine is rapidly absorbed. Plasma peak levels following an oral dose occur after 15-60 minutes, and following IV injection occur after 15 minutes. Extensively metabolized by the liver, only 2-12% is excreted as unchanged drug, while 60-80% is excreted as morphine-3glucuronide. The half-life of mo ...
Plasma osmolality ≈ 290 mosmoles. kg H 2 O
Plasma osmolality ≈ 290 mosmoles. kg H 2 O

... • So, intracranial disease may lead to a disturbance in its control over ANP secretion ...
Case report / Olgu sunumu AN ACUTE DYSTONIA CASE INDUCED
Case report / Olgu sunumu AN ACUTE DYSTONIA CASE INDUCED

... dystonia is abundant. The mechanism of acute dystonia in humans is still unclear, but the connection between the serotonergic and dopaminergic systems seems to play a major role. In addition some tests performed with primates, such as application of intrastrial acetylcholine, carbachol or antipsycho ...
Jane Stewart`s CV - Concordia University
Jane Stewart`s CV - Concordia University

... Stewart,  J.,  Pottier,  J.,  &  Kaczender-­‐Henrik,  E.    Male  copulatory  behavior  in  the  female  rat  after  perinatal   treatment  with  an  antiandrogenic  steroid.    Hormones  and  Behavior,  1971,  2,  247-­‐254.   Arnkoff,  D ...
Neuroscience of Sleep - University of Ilorin
Neuroscience of Sleep - University of Ilorin

... • The timing of and need for sleep (and wakefulness) are governed by the shifting balance of two intrinsic regulatory process: The circadian rhythm of alertness and sleepiness; and the homeostatic drive for NREM sleep. • The longer we are awake the greater our need for NREM Stage 3 sleep. The homoeo ...
Novel pharmacotherapeutic treatments for cocaine addiction R E V I E W
Novel pharmacotherapeutic treatments for cocaine addiction R E V I E W

... However, these medications have shown some promise and merit further clinical investigation, particularly as cognitive enhancement during early abstinence becomes a more prominent focus in addictions research and these agents may also be helpful in this area. Modafinil is a novel stimulant-like medi ...
SIADH, DI and Cerebral Salt Wasting
SIADH, DI and Cerebral Salt Wasting

... • Also localized in hypothalamus – Secreted in response to increased pressure or stretch – Similar effects to ANP – BNP levels are elevated in patients with SAH – Acute intracranial disease may cause release of cardiac BNP, and hypothalamic damage may also ...
Learning Innate Face Preferences
Learning Innate Face Preferences

... et al., 1997). Moreover, some neurons in the adult superior colliculus/pulvinar pathway appear to be selective for faces (Morris et al., 1999), although such neurons have not yet been found in young animals. The model also helps explain why infants after one month of age show a reduced interest in f ...
- Wiley Online Library
- Wiley Online Library

... Despite dedicated investigations for well over a century (Haldane & Priestley, 1905), the central respiratory chemoreflex has revealed its secrets grudgingly. We know at present that this reflex is modulated by countless brain pathways and transmitters (Nattie, 2011). However, far less is known rega ...
A COMPARATIVE STUDY OF THE EFFECT OF ONDANSETRON
A COMPARATIVE STUDY OF THE EFFECT OF ONDANSETRON

... compared to control (Table 2). However, there was no significant difference between alprazolam and ondansetron (1 mg/kg) treated rats in the time spent in the central and peripheral areas. Rats treated with granisetron did not show any significant change in the time spent in peripheral and central a ...
Is neocortex essentially multisensory?
Is neocortex essentially multisensory?

... presented targets [37]. Based on these data, it is clear that association cortical areas have an important role to play in multimodally driven behaviours. Nevertheless, for many behaviors (if not all) and contexts, synthesis of information from different modalities might be achieved, enhanced or pro ...
Identification of a Functional Connectome for Long
Identification of a Functional Connectome for Long

... where Fos expression co-varies across mice, and presumably form components of a network that are co-active during recall of long-term fear memory. This analysis suggested that expression of a long-term fear memory is an emergent property of large scale neural network interactions. This network has a ...
A Means to Address Regional Variability in Intestinal
A Means to Address Regional Variability in Intestinal

... float over the gastric contents and remain in the stomach for a prolonged period (23,24). While the system floats over the gastric contents, the drug is released slowly at the desired rate (25, 26), which results in increased GRT and reduces fluctuation in plasma drug concentration (27). Floating sy ...
the emergence of cerebral asymmetries in early human
the emergence of cerebral asymmetries in early human

... instead functionally asymmetrical from the start? A related question is whet.her functional asymmet.ries can be traced to some lat.eral bias in the structural development of the hemispheres, such t.hat. one hemisphere matures in advance of t.he other. Thus, the term "emergence" in t.he t.itle of thi ...
Antifungals
Antifungals

... – Synergy with amphotericin B has been demonstrated  The altered permeability of the fungal cell membrane produced by amphotericin allows enhanced uptake of flucytosine ...
Appendix I  163
Appendix I 163

... (Pascual-Marqui et al., 1999). The technique has previously been used in the evaluation of acute effects of psychoactive drugs (Anderer et al., 2000; Frei et al., 2001). To our knowledge, regional brain electrical activity has not been evaluated previously by means of LORETA following the administra ...
Sensory Adaptation and Short Term Plasticity as Bayesian
Sensory Adaptation and Short Term Plasticity as Bayesian

... observed presynaptic activity divided by the total estimate of the presynaptic excitability (see Methods for details). The effect of this optimal adaptation rule is to normalize the inputs from each presynaptic neuron. Inputs from presynaptic neurons with high excitability will tend to have low gain ...
A neural theory of speech acquisition and production
A neural theory of speech acquisition and production

... the speech sound map learn the expected pattern of acoustic stimulation associated with a specific syllable, represented as trajectories of the formant frequencies (or ratios of formant frequencies; see Guenther et al., 1998) defining a target speech sound. As described above, this learning is rapid a ...
DOI: 10.1161/CIRCULATIONAHA.106.181424 published online Feb
DOI: 10.1161/CIRCULATIONAHA.106.181424 published online Feb

... the 2005 publication of a Science Advisory on the use of nonsteroidal antiinflammatory drugs (NSAIDs) by the American Heart Association,1 several important events have occurred that have served as the catalyst for this update for clinicians. (1) Additional data from randomized controlled trials of c ...
Synapses formed by normal and abnormal hippocampal mossy fibers
Synapses formed by normal and abnormal hippocampal mossy fibers

... with large spines or excrescences of both hilar mossy cells and CA3 pyramidal neurons. Interneurons of the hilar region and area CA3 are also prominent targets of mossy fibers. The tracing of biocytin-filled mossy fibers and immunolabeling of target cells with interneuron markers has revealed that t ...
QA324_3_Which_Drugs_Cause_NMS
QA324_3_Which_Drugs_Cause_NMS

... patient experienced symptoms of NMS due to a reduced dose of amantadine which resolved on the dose being increased. The symptoms recurred following re-challenge, then resolved the dose was increased.(21) Bromocriptine and levodopa have been used successfully as treatments for NMS caused by dopamine ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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