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Bolsum and PAM Matrix
Bolsum and PAM Matrix

... • The purpose of an insertion is to increase the strength of the alignment. • So choosing a high score will eliminate sequences with gaps while of the score is too low then alignments with more and larger gaps will be chosen. • The value should also be dependent on how closely “related” the alignmen ...
Unit 4 Review Sheet - Answers
Unit 4 Review Sheet - Answers

... ribosome in the cytoplasm - Do you know how to use the codon chart? - Why is the sequence of amino acids important to the shape and function of a protein? The sequence of aa determines the shape of the protein. Proteins have a specific shape and function, therefore have a specific sequence of aa. *Y ...
TPJ_4378_sm_FigS1-7
TPJ_4378_sm_FigS1-7

... Figure S7. Amino acid sequence of MPL1 and homology to key regions of lipases. (a) Amino acid sequence of MPL1. Residues S190, D360 and H393 (all marked in black bold) are likely active site residues based on sequence of other TAG lipases. Underlined sequence GHSLG corresponds to the GXSXG motif, co ...
Chapter 15 Reading Guide - Student
Chapter 15 Reading Guide - Student

... 33. What is a synonymous substitution (also called a silent substitution)? (You should already know this.) Despite not affecting the functioning of a protein, what other consequences of this substitution exists? ...
Forever Lite® Meal Replacement – Chocolate, Vanilla
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4 Titration Curve of an Amino Acid
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... addition to the ionizable protons of the α-COOH and α-NH3 groups, they also have a dissociable proton in their R group. Although triprotic amino acids can exist as zwitterions, under physiological conditions these amino acids will be charged. If the net charge under physiological conditions is negat ...
anmol publications pvt. ltd.
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The synthesis of peptides and proteins containing non
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... contains Glu78 and Glu172, which lie y5.5 Å apart and function as the active site nucleophile and the general acid catalyst respectively. In previous work a Glu78Asp mutant, where the carboxylate–carboxylate distance is larger than in the wild-type enzyme, was studied, but was found to have little ...
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... In nature, when two enantiomers exist, usually only one is synthesized and used by cells. In the case of the amino acids, only the L configuration exists in nature and is used by cells. Some bacteria and fungi synthesize and use D configuration amino acids. The molecules synthesized with these D-for ...
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... b) The Hill coefficient is determined from the slope where the curve is steeply rising ≈ 2.8 (values between 2.5 -3.5 are acceptable) c) The minimum number of binding sites is the integer greater than your Hill coefficient. If nH < 3, the minimum number of binding sites is 3. If nH =3, or if nH < 4, ...
Biology 164 Laboratory Introduction to Bioinformatics and Molecular
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... The Clustalx software runs a mathematical algorithm that aligns multiple sequences in ways that minimize the differences between them. If you think about the types of changes that occur to genes over time, e.g., point mutations, reading frame shifts, codon transpositions or deletions, etc., you begi ...
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DNA (Gene) Mutations
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Final Quiz - GEP Community Server
Final Quiz - GEP Community Server

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DNA and RNA Chapter 12 - Nampa School District
DNA and RNA Chapter 12 - Nampa School District

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topic 5 : expression of biological information

... To function as the heritable genetic code, DNA molecules must have all of the following structural features EXCEPT A. the ability to form complementary base pairs with other DNA nucleotides. B. the ability to form complementary base pairs with RNA nucleotides C. histone proteins associated with the ...
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Genetic code



The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.
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