A new metabolomic assay to examine inflammation and redox
... accumulate in cells, it does not contribute significantly to cellular redox regulation directly. GGT expression is increased in conditions of inflammation and oxidative stress and acts as an important part in the cellular redox regulation [25-27]. ...
... accumulate in cells, it does not contribute significantly to cellular redox regulation directly. GGT expression is increased in conditions of inflammation and oxidative stress and acts as an important part in the cellular redox regulation [25-27]. ...
Small aminoacyl transfer centers at GU within a larger RNA
... Separate aminoacyl transfer centers related to the small …GUNNN..: NNNU ribozyme seem possible at the frequent GU sequences dispersed throughout an RNA tertiary structure. In fact, such activity is easily detected and varies more than 2 orders in rate, probably being faster at sites with less struct ...
... Separate aminoacyl transfer centers related to the small …GUNNN..: NNNU ribozyme seem possible at the frequent GU sequences dispersed throughout an RNA tertiary structure. In fact, such activity is easily detected and varies more than 2 orders in rate, probably being faster at sites with less struct ...
Engineering of cyclodextrin glycosyltransferase reaction and
... BIOSON Research Institute and Laboratory of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands Received 9 February 2000; received in revised form 1 August 2000; accepted 28 August 2000 ...
... BIOSON Research Institute and Laboratory of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands Received 9 February 2000; received in revised form 1 August 2000; accepted 28 August 2000 ...
Amino Acid Sequences of Peptides from a Tryptic Digest of a Urea
... criteria: (a) fractionation by paper electrophoresis and Amino acid compo8ition of fraction8s IT/2-a 2 The average composition of this group of fractions was paper chromatography revealed only one component; (b) obtained by two methods: (a) by calculation from the; the peptide consisted of amino aci ...
... criteria: (a) fractionation by paper electrophoresis and Amino acid compo8ition of fraction8s IT/2-a 2 The average composition of this group of fractions was paper chromatography revealed only one component; (b) obtained by two methods: (a) by calculation from the; the peptide consisted of amino aci ...
Journal of Microbiology and Biotechnology
... polymyxa E681 were investigated, which showed the existence of only an indole-3-pyruvic acid (IPA) pathway for IAA biosynthesis from the bacterium. Four open reading frames (ORFs) encoding indole-3-pyruvate decarboxylaselike proteins and putative indole-3-pyruvate decarboxylase (IPDC), a key enzyme ...
... polymyxa E681 were investigated, which showed the existence of only an indole-3-pyruvic acid (IPA) pathway for IAA biosynthesis from the bacterium. Four open reading frames (ORFs) encoding indole-3-pyruvate decarboxylaselike proteins and putative indole-3-pyruvate decarboxylase (IPDC), a key enzyme ...
DNA Type Lookuup Tool Instructions
... Allele codes are a short hand alphabetic notation used by the NMDP to capture DNA based allele combinations in our database. Once a new allele combination is encountered, an allele code is assigned to that allele combination and it’s then made available (activated) for use at that specific locus, an ...
... Allele codes are a short hand alphabetic notation used by the NMDP to capture DNA based allele combinations in our database. Once a new allele combination is encountered, an allele code is assigned to that allele combination and it’s then made available (activated) for use at that specific locus, an ...
Lecture 2 Sequence Alignment
... • the sequences we’re comparing probably differ in length • there may be only a relatively small region in the sequences that match • we want to allow partial matches (i.e. some amino acid pairs are more substitutable than others) • variable length regions may have been inserted/deleted from the ...
... • the sequences we’re comparing probably differ in length • there may be only a relatively small region in the sequences that match • we want to allow partial matches (i.e. some amino acid pairs are more substitutable than others) • variable length regions may have been inserted/deleted from the ...
Connection of Propionyl-CoA Metabolism to Polyketide
... the vector pBluescript SK (Stratagene) sequentially to construct the disruption vector pYQ8.4. Plasmid pYQ8.4 was transformed into RRAW7 to delete pcsA by homologous recombination. The fungal transformation technique followed that of Miller et al. (1985) with the modification of embedding the protop ...
... the vector pBluescript SK (Stratagene) sequentially to construct the disruption vector pYQ8.4. Plasmid pYQ8.4 was transformed into RRAW7 to delete pcsA by homologous recombination. The fungal transformation technique followed that of Miller et al. (1985) with the modification of embedding the protop ...
Lecture 03, NEW - terpenes + polyketides
... Isolated in 1960 after thousands of turkeys died of liver failure from eating moldy peanut meal; culprit was Aspergillus mold ...
... Isolated in 1960 after thousands of turkeys died of liver failure from eating moldy peanut meal; culprit was Aspergillus mold ...
Modeling Multi-typed Structurally Viewed Chemicals with the UMLS
... because some of the original structural components are expended in its creation. The neutralization reaction of an acid and a base producing a salt is a simple example of this scenario. The new chemical, salt, contains parts of acid and base; however, it is neither an acid nor a base. In this sense, ...
... because some of the original structural components are expended in its creation. The neutralization reaction of an acid and a base producing a salt is a simple example of this scenario. The new chemical, salt, contains parts of acid and base; however, it is neither an acid nor a base. In this sense, ...
BLUEPRINT OF THE CORE TOPICS IN BIOCHEMISTRY
... _C__3. At its isoelectric point, an amino acid is: A. fully protonated B. fully ionized C. uncharged D. a good buffer _B__4. The secondary level of protein structure is maintained by: A. Peptide bonds between amino acid residues B. Hydrogen bonds between peptide bonds C. Hydrogen bonds between R gro ...
... _C__3. At its isoelectric point, an amino acid is: A. fully protonated B. fully ionized C. uncharged D. a good buffer _B__4. The secondary level of protein structure is maintained by: A. Peptide bonds between amino acid residues B. Hydrogen bonds between peptide bonds C. Hydrogen bonds between R gro ...
for students of the Faculty of Medicine
... Amino acids are among the best-known components of living organisms. They are derived from organic acids, in which a hydrogen atom most often located near the α-carbon is substituted by the amino group. Some amino acids have two amino groups located at different carbon atoms, a few contain two or ev ...
... Amino acids are among the best-known components of living organisms. They are derived from organic acids, in which a hydrogen atom most often located near the α-carbon is substituted by the amino group. Some amino acids have two amino groups located at different carbon atoms, a few contain two or ev ...
Translation of Cyclin mRNA Is Necessary for Extracts of Activated
... al., 1979; Kishimoto et al., 1982; Weintraub et al., 1982; Gerhart et al., 1984; Meijer and Guerrier, 1984). MPF can also drive GP-arrested cells into mitosis (Miake-Lye et al., 1983; Newport and Kirschner, 1984; Kirschner et al., 1985). Thus, MPF is an almost universal concomitant of M phase, and i ...
... al., 1979; Kishimoto et al., 1982; Weintraub et al., 1982; Gerhart et al., 1984; Meijer and Guerrier, 1984). MPF can also drive GP-arrested cells into mitosis (Miake-Lye et al., 1983; Newport and Kirschner, 1984; Kirschner et al., 1985). Thus, MPF is an almost universal concomitant of M phase, and i ...
Mass spectrometric analysis of tricarboxylic acid cycle
... anabolic processes. Due to this ambiguity, the cycle serves as source of energy, but also provides variety of important biosynthetic precursors. For example oxaloacetate is a starting material for gluconeogenesis and together with α-ketoglutarate also serves as molecular building block for many amin ...
... anabolic processes. Due to this ambiguity, the cycle serves as source of energy, but also provides variety of important biosynthetic precursors. For example oxaloacetate is a starting material for gluconeogenesis and together with α-ketoglutarate also serves as molecular building block for many amin ...
Citrate synthase proteins in extremophilic organisms: Studies within
... and oxaloacetate into CoA and citrate3 – is executed properly. In this paper, we investigate to what extent structurebased coarse-grained models, or rather their one specific implementation, can capture physical differences between proteins which belong to the same fold. We study four CS proteins and ...
... and oxaloacetate into CoA and citrate3 – is executed properly. In this paper, we investigate to what extent structurebased coarse-grained models, or rather their one specific implementation, can capture physical differences between proteins which belong to the same fold. We study four CS proteins and ...
Neighbor-Dependent Ramachandran Probability Distributions of
... Distributions of the backbone dihedral angles of proteins have been studied for over 40 years. While many statistical analyses have been presented, only a handful of probability densities are publicly available for use in structure validation and structure prediction methods. The available distribut ...
... Distributions of the backbone dihedral angles of proteins have been studied for over 40 years. While many statistical analyses have been presented, only a handful of probability densities are publicly available for use in structure validation and structure prediction methods. The available distribut ...
Molecular Characterisation of the 76 kDa Iron
... the mitochondrial respiratory chain vary in their locations between the mitochondrial and nuclear genomes in different organisms, whereas genes for a homologous multisubunit complex in chloroplasts have to date only been found on the plastid genome. In potato (Solatium tuberosum L.), the gene coding ...
... the mitochondrial respiratory chain vary in their locations between the mitochondrial and nuclear genomes in different organisms, whereas genes for a homologous multisubunit complex in chloroplasts have to date only been found on the plastid genome. In potato (Solatium tuberosum L.), the gene coding ...
The Evolution of Genetic Architecture
... epistasis defined without regard to allele frequencies and showed how this physiological epistasis differed from the Fisherian notion of statistical epistasis and even contributed to the additive genetic variance. The Fisherian regression model minimizes the statistical influence of gene interactions ...
... epistasis defined without regard to allele frequencies and showed how this physiological epistasis differed from the Fisherian notion of statistical epistasis and even contributed to the additive genetic variance. The Fisherian regression model minimizes the statistical influence of gene interactions ...
Study on the degradability of poly(ester amide)s derived from the... acids glycine, and l-alanine containing a variable amide/ester ratio
... The series of poly(ester amide)s PDAxGHGy8 and PDAxAHAy8 were synthesized by interfacial polymerization following the procedure outlined in Scheme 1, which is similar to that previously reported for related derivatives with a sequential composition [11±13]. In our notation, x and y refer to the perc ...
... The series of poly(ester amide)s PDAxGHGy8 and PDAxAHAy8 were synthesized by interfacial polymerization following the procedure outlined in Scheme 1, which is similar to that previously reported for related derivatives with a sequential composition [11±13]. In our notation, x and y refer to the perc ...
Fatty acid and phospholipid metabolism in prokaryotes
... strains with the fabl(Ts) mutation grow at 30°C, but are not viable at 42°C. This type of defect is usually ascribed to an amino acid change in an essential enzyme that renders it unstable at higher temperatures. Techniques using the bacteriophage PI are available for the movement of these alleles i ...
... strains with the fabl(Ts) mutation grow at 30°C, but are not viable at 42°C. This type of defect is usually ascribed to an amino acid change in an essential enzyme that renders it unstable at higher temperatures. Techniques using the bacteriophage PI are available for the movement of these alleles i ...
Document
... Genocentric view and Central Dogma ‘Genocentric’ view runs into problem when one start to deal with the multicellular organisms exhibiting the phenomenon of cellular differentiation Phenomenon of iPS cell reprogramming and somatic cloning – genetic information is not sufficient to define the state ...
... Genocentric view and Central Dogma ‘Genocentric’ view runs into problem when one start to deal with the multicellular organisms exhibiting the phenomenon of cellular differentiation Phenomenon of iPS cell reprogramming and somatic cloning – genetic information is not sufficient to define the state ...
Evidence for the presence of photorespiration in desiccation
... such as serine and glycine (Madore and Grodzinksi, 1984). Many studies have shown that photorespiration can be important for energy dissipation to prevent photoinhibition (Osmond, 1981; Wu et al., 1991; Osmond and Grace, 1995; Kozaki and Takeba, 1996; Osmond et al., 1997; Igamberdiev et al., 2001). ...
... such as serine and glycine (Madore and Grodzinksi, 1984). Many studies have shown that photorespiration can be important for energy dissipation to prevent photoinhibition (Osmond, 1981; Wu et al., 1991; Osmond and Grace, 1995; Kozaki and Takeba, 1996; Osmond et al., 1997; Igamberdiev et al., 2001). ...
Additional file 1
... Hydrolyze phospholipids for the release of secondary messenger that participate in different signal transduction pathway Lipid metabolism ...
... Hydrolyze phospholipids for the release of secondary messenger that participate in different signal transduction pathway Lipid metabolism ...
Genetic code
The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.