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B12 Deficiency
B12 Deficiency

... your B12 activity was in the past several weeks) Homocysteine (functional test not only for B12 but also becomes abnormal in folic acid or B6 deficiency) ...
Comparative genomics provides evidence for the 3
Comparative genomics provides evidence for the 3

... heavier isotopes of carbon (incorporated as bicarbonate) than does the Calvin cycle. This leads to the synthesis of organic compounds that are relatively enriched in 13C (Dd13C ~14‰) compared with those produced by the Calvin cycle (Dd13C ~20–25‰) (Holo and Sirevåg, 1986; Madigan et al., 1989; van d ...
Practice Problems on Amino Acids and Peptides
Practice Problems on Amino Acids and Peptides

... Biological molecules often have phosphate or pyrophosphate monoester groups. Which one of the following statements regarding this is least correct? A) The phosphate or pyrophosphate provides a handle for electrostatic binding of the molecule by an enzyme B) Phosphates or pyrophosphates will accept h ...
Synergistic Inhibitory Effects of Hypoxia and Iron
Synergistic Inhibitory Effects of Hypoxia and Iron

... were observed in hypoxic mice; hepatic lactate did not differ among the groups (Fig. 4C and D). These results suggest that decreased utilization of pyruvate for gluconeogenesis may have been occurring in the liver, so we next investigated the metabolic fates of pyruvate in the liver under hypoxia wi ...
Chapter 2: Biochemistry Problems
Chapter 2: Biochemistry Problems

... as lipids and phospholipids, carbohydrates, proteins, or nucleic acids. You might study pathways such as glycolysis or photosynthesis, or any other metabolic pathway. In this chapter, we begin with problems that review the bonds and forces that hold these macromolecules together. We briefly touch on ...
The biological synthesis of cholesterol
The biological synthesis of cholesterol

... complex molecule might be constructed from the smaller molecules available in the cell. It is, therefore, all the more remarkable that much of the early speculative thinking came so close to predicting some of the general principles that were eventually shown to operate in sterol biosynthesis. The e ...
Metabolic effects of glutamine on insulin sensitivity
Metabolic effects of glutamine on insulin sensitivity

... released and transported to different organs (2, 3). Gln promotes and maintains the function of different cells and tissues, including the intestines (4), liver (5), neurons (6), lymphocytes (7), and kidney (8). Gln is a precursor of proteins, peptides, amino sugars, purines, and pyrimidines involve ...
Human Physiology: An Integrated Approach Molecular Interactions 1
Human Physiology: An Integrated Approach Molecular Interactions 1

... 20) All of these statements about carbohydrates are true except one. Identify the exception. A) Simple sugars include lactose, glucose, and ribose. B) Cellulose is the most abundant carbohydrate on earth. C) Glycogen is a storage polysaccharide made by animal cells. D) Polysaccharides are important ...
Engineering Cytosolic Acetyl-CoA Metabolism in
Engineering Cytosolic Acetyl-CoA Metabolism in

... A Saccharomyces cerevisiae strain carrying deletions in all three pyruvate decarboxylase genes (also called Pdc negative yeast) represents a non-ethanol producing platform strain for biochemical production. However, it cannot grow on glucose as the sole carbon source due to the lack of cytosolic ace ...
Ch13.doc
Ch13.doc

... 21. Synthesis of acetyl-CoA from acetate: Acetate + CoA + ATP  acetyl-CoA + AMP + PPi a. The ΔGo’ of the hydrolysis of acetyl-CoA to acetate and CoA is -31.4 kJ/mole (in the table below, -32.5kJ/mole in the EOC problem) which is clearly more than ATP + H2O  ADP + Pi (30 kJ/mole) which means the us ...
2. Lect. Urea cycle
2. Lect. Urea cycle

... Regulation of the urea cycle N-Acetylglutamate is an essential activator for carbamoyl phosphate synthetase I—the rate-limiting step in the urea cycle. NAcetylglutamate is synthesized from acetyl coenzyme A and glutamate by N-acetylglutamate synthase , in a reaction for which arginine is an activat ...
Selected Solutions to End of Chapter 13 Problems
Selected Solutions to End of Chapter 13 Problems

... 21. Synthesis of acetyl-CoA from acetate: Acetate + CoA + ATP  acetyl-CoA + AMP + PPi a. The ΔGo’ of the hydrolysis of acetyl-CoA to acetate and CoA is -31.4 kJ/mole (in the table below, -32.5kJ/mole in the EOC problem) which is clearly more than ATP + H2O  ADP + Pi (30 kJ/mole) which means the us ...
Isolation and Fractionation 2
Isolation and Fractionation 2

... sediment to the bottom of the tube whilst the less dense lysosomes rise to the interface of the 14.3% and 34.5% sucrose. The lysosomal layer can be removed, harvested by further centrifugation and then resuspended in iso-osmotic 0.25 M sucrose. Conversely lysosomes can be made more dense by injectin ...
The Enzymic Activity of the Outer Shell of
The Enzymic Activity of the Outer Shell of

... contents by washing and centrifugation. Such preparations have been called cellwall membranes because they have the form and chemical constituents of the cell wall and also the phospholipid components and enzymic activities associated with the cytoplasmic membrane. In the present work similar prepar ...
The Enzymic Activity of the Outer Shell of
The Enzymic Activity of the Outer Shell of

... contents by washing and centrifugation. Such preparations have been called cellwall membranes because they have the form and chemical constituents of the cell wall and also the phospholipid components and enzymic activities associated with the cytoplasmic membrane. In the present work similar prepar ...
linolenic acid prevent insulin resistance but have divergent impacts
linolenic acid prevent insulin resistance but have divergent impacts

... relationship between IR and ␣-linolenic acid (ALA). Although ALA can be endogenously converted into EPA/DHA, tracer studies have revealed that the conversion efficiency is low (⬍8%) (44, 54). Therefore, it is conceivable that ALA and EPA/DHA have divergent effects on insulin sensitivity, although th ...
Mechanical and metabolic functions in pig hearts after 4
Mechanical and metabolic functions in pig hearts after 4

... increase in exogenous glucose utilization when normalized by perfusion (i.e., the "flow-metabolic mismatch" [4-8]) while at the same time retaining the capacity of oxidative metabolism (9). The presence of increased glucose metabolism has served as a reliable clinical marker to successfully predict ...
Phar 722 Pharmacy Practice III
Phar 722 Pharmacy Practice III

... – Egg white contains a basic protein known as avidin which forms salt linkages with the acidic biotin that might be in the intestinal tract (possibly produced by intestinal bacteria?). • This complex is not absorbed, but remains in the intestine eventually to be excreted. ...
from Scolopendra subspinipes mutilans
from Scolopendra subspinipes mutilans

... previous studies [5, 6]. The venoms also play significant biologic roles in the synthesis of proteins, peptides and enzymes. In a recent study, centipede venoms that contained about 500 proteins and peptides were involved in platelet aggregating activity, phospholipaseA2 activity, anticoagulant acti ...
mammalian hibernation: biochemical adaptation
mammalian hibernation: biochemical adaptation

... mammals arise from two main effects of cold on metabolic systems that have been optimized over millions of years of mammalian evolution for function within a narrow temperature window. The first is the differential effect of temperature change on the rates of thousands of cellular reactions that can ...
Oxidative metabolism in thermogenic tissues of the swordfish and
Oxidative metabolism in thermogenic tissues of the swordfish and

jr. division set 1
jr. division set 1

... Correct answers are worth 10 points each. ...
Fermentation for Liquid-type Yogurt with Lactobacillus casei 911LC
Fermentation for Liquid-type Yogurt with Lactobacillus casei 911LC

... 2 ml/min and two mobile phases were used: solvent A was 0.05 M sodium acetate (pH 6.3), and solvent B, methanol: Changes in pH and titratable acidity THF (90:10, v/v). The linear gradient of solvent B was Changes in pH during the 72 h fermentation of yogurt programmed at 5 levels as follows: initial ...
Chapter 9
Chapter 9

...  In cellular respiration, glucose and other organic molecules are broken down in a series of steps  Electrons from organic compounds are usually first transferred to NAD+, a coenzyme  As an electron acceptor, NAD+ functions as an oxidizing agent during cellular respiration  Each NADH (the reduce ...
Chapter 3
Chapter 3

... – Neuromuscular Recruitment Model: increased ability of brain to recruit muscles (e.g., coordination, effectiveness). ...
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Fatty acid metabolism

Fatty acids are a family of molecules classified within the lipid macronutrient class. One role of fatty acids within animal metabolism is energy production in the form of adenosine triphosphate (ATP) synthesis. When compared to other macronutrient classes (carbohydrates and protein), fatty acids yield the most ATP on an energy per gram basis by a pathway called β-oxidation. In addition, fatty acids are important for energy storage, phospholipid membrane formation, and signaling pathways. Fatty acid metabolism consists of catabolic processes that generate energy and primary metabolites from fatty acids, and anabolic processes that create biologically important molecules from fatty acids and other dietary sources.
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