C YTOKINES AND IMMUNE BALANCE IN PREECLAMPSIA
... Preeclampsia is one of the most feared pregnancy complications, with a risk of maternal and fetal death and with no ideal therapy readily available. The cause of this strictly pregnancyrelated disease is still unknown and is therefore a great challenge to all researchers in the field of pregnancy-re ...
... Preeclampsia is one of the most feared pregnancy complications, with a risk of maternal and fetal death and with no ideal therapy readily available. The cause of this strictly pregnancyrelated disease is still unknown and is therefore a great challenge to all researchers in the field of pregnancy-re ...
Carbohydrate profiling reveals a distinctive role for
... Dendritic cells (DCs) are key to the maintenance of peripheral tolerance to self-antigens and the orchestration of an immune reaction to foreign antigens. C-type lectins, expressed by DCs, recognize carbohydrate moieties on antigens that can be internalized for processing and presentation. Little is ...
... Dendritic cells (DCs) are key to the maintenance of peripheral tolerance to self-antigens and the orchestration of an immune reaction to foreign antigens. C-type lectins, expressed by DCs, recognize carbohydrate moieties on antigens that can be internalized for processing and presentation. Little is ...
... system provides specific defence against foreign substances that enter the body. It is likely that the two types of responses referred to as humoral and cellular immunity co-exist, and when circulating antibodies are present, a cellular response is often demonstrable. Isocyanate-induced asthma, on t ...
Document
... together with diminished phagocytosis leads to increased bacteremia and bacterial escape from latency in mice (Bhaskaran et al. 2001; Wang et al. 2005; Lugo-Chinchilla et al. 2006). Human studies and rodent models of drug abuse indicate that morphine impairs the host’s ability to eradicate infection ...
... together with diminished phagocytosis leads to increased bacteremia and bacterial escape from latency in mice (Bhaskaran et al. 2001; Wang et al. 2005; Lugo-Chinchilla et al. 2006). Human studies and rodent models of drug abuse indicate that morphine impairs the host’s ability to eradicate infection ...
Department of Cellular Biology, Physiology and Immunology Faculty of Medicine
... SD: Standard deviation Siglec: Sialic acid binding immunoglobulin-like lectin SIRP-α: signal regulatory protein α, also known as CD172 SLO: Secondary lymphoid organs TfR: Transferrin receptor TGF-β: Transforming growth factor-β Th 1: Type 1 T helper cell TLRs: Toll-like receptors TNF: Tumour necrosi ...
... SD: Standard deviation Siglec: Sialic acid binding immunoglobulin-like lectin SIRP-α: signal regulatory protein α, also known as CD172 SLO: Secondary lymphoid organs TfR: Transferrin receptor TGF-β: Transforming growth factor-β Th 1: Type 1 T helper cell TLRs: Toll-like receptors TNF: Tumour necrosi ...
Aryl Hydrocarbon Receptor Control of Adaptive Immunity
... The immune system of zebrafish shares many features with its mammalian counterpart. We reported that the zebrafish immune system can mediate self-directed inflammation and tissue destruction (Quintana et al., 2010a). This potential self-reactivity is controlled by functional FoxP3+ Tregs, suggesting ...
... The immune system of zebrafish shares many features with its mammalian counterpart. We reported that the zebrafish immune system can mediate self-directed inflammation and tissue destruction (Quintana et al., 2010a). This potential self-reactivity is controlled by functional FoxP3+ Tregs, suggesting ...
Thymus Gland - Spirit of Health
... cows, so the calf must get it all from the colostrum. This factor may elevate colostrum`s potential in human supplementation. The spectrum of potential health benefits associated with the consumption of colostrum is innumerable. Research has shown that regular consumption of colostrum can help the ...
... cows, so the calf must get it all from the colostrum. This factor may elevate colostrum`s potential in human supplementation. The spectrum of potential health benefits associated with the consumption of colostrum is innumerable. Research has shown that regular consumption of colostrum can help the ...
Spatial and temporal regulation of cytokine expression in Type 2
... you was so uncomplicated, I enjoyed so much working together on the hookworm project, thank you for involving me in such a well-rounded study. Mali Camberis thank you for helping me with all things Nippostrongylus brasiliensis and Heligmosomoides polygyrus, from worm culture to infection and counti ...
... you was so uncomplicated, I enjoyed so much working together on the hookworm project, thank you for involving me in such a well-rounded study. Mali Camberis thank you for helping me with all things Nippostrongylus brasiliensis and Heligmosomoides polygyrus, from worm culture to infection and counti ...
FONGAnti-inflammatoryRole2010
... mice treated with anti-TNF antibody show increased STAT1 activation and IL12 expression after LPS and IFN stimulation. BMDM infected with adenovirus expressing IKKβ dominant negative rescued the inhibitory effect of TNFα on IL12p40 production, indicating TNFα inhibits IL-12p40 via IKKβ activation. ...
... mice treated with anti-TNF antibody show increased STAT1 activation and IL12 expression after LPS and IFN stimulation. BMDM infected with adenovirus expressing IKKβ dominant negative rescued the inhibitory effect of TNFα on IL12p40 production, indicating TNFα inhibits IL-12p40 via IKKβ activation. ...
Complement and its role in innate and adaptive immune
... As a consequence of this constitutive activation, and due to the ability to form a feedback amplification pathway, there are a number of complement inhibitory proteins responsible for confining complement activation to appropriate contexts to prevent errant complement activation in the healthy host, ...
... As a consequence of this constitutive activation, and due to the ability to form a feedback amplification pathway, there are a number of complement inhibitory proteins responsible for confining complement activation to appropriate contexts to prevent errant complement activation in the healthy host, ...
Modelling T Cell Activation
... presenting cells, the dendritic cells (DCs), sit and wait at the interfaces between the body and the environment. DCs constantly sample the environment, and then migrate to the secondary lymphoid organs (lymph nodes and spleen) where they present their captured antigens to the T cells. If the T cel ...
... presenting cells, the dendritic cells (DCs), sit and wait at the interfaces between the body and the environment. DCs constantly sample the environment, and then migrate to the secondary lymphoid organs (lymph nodes and spleen) where they present their captured antigens to the T cells. If the T cel ...
Full text - Universiteit Leiden
... cardiovascular events are associated with myocardial infarction and stroke as a result of a ruptured plaque and a subsequent thrombotic event (Figure 1.1C).32, 33 Plaque rupture is the final outcome of plaque destabilization. During lesion development activated macrophages, T cells and other immune ...
... cardiovascular events are associated with myocardial infarction and stroke as a result of a ruptured plaque and a subsequent thrombotic event (Figure 1.1C).32, 33 Plaque rupture is the final outcome of plaque destabilization. During lesion development activated macrophages, T cells and other immune ...
Immune Notes 1 - Little Miami Schools
... -Antigens are unique molecules recognized by the immune system that mark cells, viruses, etc. ...
... -Antigens are unique molecules recognized by the immune system that mark cells, viruses, etc. ...
The immune system
... Cell mediated T cells are responsible for. They destroy targets foreing cells by themselves or they „call“ other cells to help them ...
... Cell mediated T cells are responsible for. They destroy targets foreing cells by themselves or they „call“ other cells to help them ...
Chitin, Chitinases and Chitinase
... exogenous chitin activates macrophages and other innate immune cells and also modulates adaptive type 2 allergic inflammation. These studies further demonstrate that chitin stimulate macrophages by interacting with different cell surface receptors such as macrophage mannose receptor, toll-like recep ...
... exogenous chitin activates macrophages and other innate immune cells and also modulates adaptive type 2 allergic inflammation. These studies further demonstrate that chitin stimulate macrophages by interacting with different cell surface receptors such as macrophage mannose receptor, toll-like recep ...
Welcome to the Nature Immunology Immune Evasion Web Focus
... tumors from the body. In spite of the excellent array of preventative measures at hand, everyone has suffered microbial infections or knows an individual who has developed cancer. This is because the most successful tumors and pathogens have coevolved with us and developed a panoply of ploys to esca ...
... tumors from the body. In spite of the excellent array of preventative measures at hand, everyone has suffered microbial infections or knows an individual who has developed cancer. This is because the most successful tumors and pathogens have coevolved with us and developed a panoply of ploys to esca ...
Intracellular NAD+ levels are associated with LPS-induced TNF
... the intricacies of the level of linkage. NAD + has previously been shown to regulate tumour necrosis factor-α (TNF-α) synthesis and TNF-α has been shown to regulate NAD + homoeostasis providing a link between a pro-inflammatory response and redox status. In the present study, we have used THP-1 diff ...
... the intricacies of the level of linkage. NAD + has previously been shown to regulate tumour necrosis factor-α (TNF-α) synthesis and TNF-α has been shown to regulate NAD + homoeostasis providing a link between a pro-inflammatory response and redox status. In the present study, we have used THP-1 diff ...
Role and prognostic importance of regulatory T cells in lung cancer
... Tregs in the TLS as well as non-TLS areas of the lung tumors. Ti-Tregs (tumor infiltrating Tregs) mainly exhibit central memory and effector memory phenotype expressing vast repertoire of the activation and ICP (immune checkpoint) molecules. The gene expression and flow cytometry experiments showed ...
... Tregs in the TLS as well as non-TLS areas of the lung tumors. Ti-Tregs (tumor infiltrating Tregs) mainly exhibit central memory and effector memory phenotype expressing vast repertoire of the activation and ICP (immune checkpoint) molecules. The gene expression and flow cytometry experiments showed ...
Complement: a key system for immune surveillance and homeostasis
... to other systems (Supplementary Fig. 1). Depending on the trigger, several initiation and regulatory mechanisms act together to produce an anticipated result in immune surveillance (Figs. 1 and 2). The classical pathway is often referred to as antibody-dependent because it is strongly initiated by I ...
... to other systems (Supplementary Fig. 1). Depending on the trigger, several initiation and regulatory mechanisms act together to produce an anticipated result in immune surveillance (Figs. 1 and 2). The classical pathway is often referred to as antibody-dependent because it is strongly initiated by I ...
xia immune activation 1
... and NKT cells, are also activated in other inflamed organs, such as the liver, to contribute indirectly to the atherosclerosis by increasing systemic inflammation and metabolic dysfunction. However, molecular events that link activation of different immune cells and abnormal metabolic conditions in ...
... and NKT cells, are also activated in other inflamed organs, such as the liver, to contribute indirectly to the atherosclerosis by increasing systemic inflammation and metabolic dysfunction. However, molecular events that link activation of different immune cells and abnormal metabolic conditions in ...
Current Topics in Microbiology and Immunology
... probably important for many aspects of normal and malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation. The first main section includes three chapters, where the first review by Bonecchi et al. d ...
... probably important for many aspects of normal and malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation. The first main section includes three chapters, where the first review by Bonecchi et al. d ...
T cell
T cells or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that plays a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells rearrange their alpha/beta T cell receptors and are termed alpha beta T cells and are part of adaptive immune system. Specialized gamma delta T cells, which comprise a minority of T cells in the human body (more frequent in ruminants), have invariant TCR (with limited diversity), can effectively present antigens to other T cells and are considered to be part of the innate immune system.