Nature Medicine 10, 1307
... per se have not been the main subjects of investigation, but myeloid cells have certainly come to the fore as key players in the guise of dendritic cells (DCs), which are thought to orchestrate the extent and quality of antigen-specific immune responses. An entirely new appreciation has emerged of n ...
... per se have not been the main subjects of investigation, but myeloid cells have certainly come to the fore as key players in the guise of dendritic cells (DCs), which are thought to orchestrate the extent and quality of antigen-specific immune responses. An entirely new appreciation has emerged of n ...
Immune tolerance by interferon-alpha in experimental arthritis Jaya Prakash Chalise Linköping University
... IFN-α inhibits pro-inflammatory cytokines but increases TGF-β during AIA (Paper II).................. 38 The protective effect of IFN-α in AIA is mediated by TGF-β1 (Paper III) ........................................ 43 Indoleamine 2, 3 dioxygenase and IFN-α-protection of AIA (Paper III) .......... ...
... IFN-α inhibits pro-inflammatory cytokines but increases TGF-β during AIA (Paper II).................. 38 The protective effect of IFN-α in AIA is mediated by TGF-β1 (Paper III) ........................................ 43 Indoleamine 2, 3 dioxygenase and IFN-α-protection of AIA (Paper III) .......... ...
Profound CD4+/CCR5+ T cell expansion is induced by CD8+
... of rhesus macaques (RMs) results in irreversible prolongation of peak-level viral replication and rapid disease progression, consistent with a major role for CD8+ lymphocytes in determining postacute-phase viral replication set points. However, we report that CD8+ lymphocyte depletion is also associ ...
... of rhesus macaques (RMs) results in irreversible prolongation of peak-level viral replication and rapid disease progression, consistent with a major role for CD8+ lymphocytes in determining postacute-phase viral replication set points. However, we report that CD8+ lymphocyte depletion is also associ ...
The Role of Intracellular Neutral Lipid Hydrolases in Immune Cell
... for the get-away weekends to Vienna and for the hiking trips, which helped a lot to redefine true values in life again. My special thanks go to Andrea for our friendship during the last and hopefully upcoming years. Thanks for being such an unbelievable source of energy and for your infectious motiv ...
... for the get-away weekends to Vienna and for the hiking trips, which helped a lot to redefine true values in life again. My special thanks go to Andrea for our friendship during the last and hopefully upcoming years. Thanks for being such an unbelievable source of energy and for your infectious motiv ...
requirements for memory b cell and long lived plasma cell
... secondary exposure to antigens or pathogens [1]. Memory responses form the basis of vaccination and protection from re-exposure to commonly encountered pathogens. Despite this, the adaptive immune mechanisms required for memory, particularly for memory to bacterial pathogens, are not completely unde ...
... secondary exposure to antigens or pathogens [1]. Memory responses form the basis of vaccination and protection from re-exposure to commonly encountered pathogens. Despite this, the adaptive immune mechanisms required for memory, particularly for memory to bacterial pathogens, are not completely unde ...
nk cell education and adhesion molecules
... Antibodies that target molecules on cancer cells have been used for some years now. They work via several mechanisms, e.g. by blocking the function of the targeted molecule on the surface of the tumor cell, induction of apoptosis, or by labeling the targeted cell for attack by immune cells. The eff ...
... Antibodies that target molecules on cancer cells have been used for some years now. They work via several mechanisms, e.g. by blocking the function of the targeted molecule on the surface of the tumor cell, induction of apoptosis, or by labeling the targeted cell for attack by immune cells. The eff ...
Suppression of adaptive immune responses during primary SIV
... responses has been demonstrated by complete protection of rhesus macaques from pathogenic SHIV89.6P challenge after passive transfer of broadly NAbs.13,14 Recently, a limited number of studies have evaluated the role of B cell–mediated immune responses in SIV containment in rhesus macaques.15-17 Hum ...
... responses has been demonstrated by complete protection of rhesus macaques from pathogenic SHIV89.6P challenge after passive transfer of broadly NAbs.13,14 Recently, a limited number of studies have evaluated the role of B cell–mediated immune responses in SIV containment in rhesus macaques.15-17 Hum ...
Immunology Program Graduates
... Interleukin-10 in the Induction of Anti-Tumor Immunity: Strategies and Mechanisms Natalya Serbina, Ph.D., 2000 Thesis Advisor: Dr. JoAnne Flynn Role of CD8+ T cells in Mycobacterium tuberculosis infection Jayakar Nayak, Ph.D., 2001 Thesis Advisor: Dr. Louis Falo Promoting Tumor-Specific Immune Respo ...
... Interleukin-10 in the Induction of Anti-Tumor Immunity: Strategies and Mechanisms Natalya Serbina, Ph.D., 2000 Thesis Advisor: Dr. JoAnne Flynn Role of CD8+ T cells in Mycobacterium tuberculosis infection Jayakar Nayak, Ph.D., 2001 Thesis Advisor: Dr. Louis Falo Promoting Tumor-Specific Immune Respo ...
chapter 16 the adaptive immune response
... The adaptive immune system has memory so we are not infected by the same pathogen a ...
... The adaptive immune system has memory so we are not infected by the same pathogen a ...
Immunohistochemical and ultrastructural localization of leptin and
... Subcutaneous and visceral tissue specimens of white human fat were obtained from normal-weight human subjects (BMI <26 kg/m2) undergoing abdominal surgery or surgical mammary reduction. The study was approved by the ethics committees of the Universities of Düsseldorf and Leipzig. Cell culture. After ...
... Subcutaneous and visceral tissue specimens of white human fat were obtained from normal-weight human subjects (BMI <26 kg/m2) undergoing abdominal surgery or surgical mammary reduction. The study was approved by the ethics committees of the Universities of Düsseldorf and Leipzig. Cell culture. After ...
An evaluation of the anti-inflammatory properties
... Humin substances have been used as folk remedies for the last 3000 years. Recent studies have shown that humates possess anti-inflammatory properties, but the mechanism of how it affects inflammation is still unclear. In this study the antiinflammatory properties of potassium humate, a water soluble ...
... Humin substances have been used as folk remedies for the last 3000 years. Recent studies have shown that humates possess anti-inflammatory properties, but the mechanism of how it affects inflammation is still unclear. In this study the antiinflammatory properties of potassium humate, a water soluble ...
28-29_Per_tolerance_Regulatory T-cells_LA
... the non-redundant function of IL-2 is in controlling immune responses (generalized autoimmune disease). In humans, CD25 deficiency causes a syndrome described as IPEX-like. Extensive lymphocytic infiltration of tissues, including lung, liver, gut and bone is observed, accompanied by tissue atrophy a ...
... the non-redundant function of IL-2 is in controlling immune responses (generalized autoimmune disease). In humans, CD25 deficiency causes a syndrome described as IPEX-like. Extensive lymphocytic infiltration of tissues, including lung, liver, gut and bone is observed, accompanied by tissue atrophy a ...
Aloe Vera and the Human Immune System
... benefitto its performance.The specialimponanceof Aloe is that its immune-active effectshavebeenclearlyshownto be of functionalbenefit. Next, it is clear,ffid well known, that the body's fight agairst tumoursis alsomediated throughthe immunesptenl which hasan ability to kill andremovetumotr cells. Th ...
... benefitto its performance.The specialimponanceof Aloe is that its immune-active effectshavebeenclearlyshownto be of functionalbenefit. Next, it is clear,ffid well known, that the body's fight agairst tumoursis alsomediated throughthe immunesptenl which hasan ability to kill andremovetumotr cells. Th ...
6. DISCUSSION
... however a relevant number of MGCs was only observed in stage II affected cases. The activation of the immune system is considered crucial for the formation of such cells in tonsils and adenoid tissues of human immunodeficiency virus affected patients (Orenstein and Wahl, 1999). Our results suggest t ...
... however a relevant number of MGCs was only observed in stage II affected cases. The activation of the immune system is considered crucial for the formation of such cells in tonsils and adenoid tissues of human immunodeficiency virus affected patients (Orenstein and Wahl, 1999). Our results suggest t ...
Chapter 1: Masters Thesis Literature Review
... those who are exposed to M. tuberculosis, only 10-30% become infected, indicating that some humans may be capable of resolving the infection on their own. Of the population that does become infected only 10% progress to active disease with the majority entering a latent phase of infection. These lat ...
... those who are exposed to M. tuberculosis, only 10-30% become infected, indicating that some humans may be capable of resolving the infection on their own. Of the population that does become infected only 10% progress to active disease with the majority entering a latent phase of infection. These lat ...
Complement-mediated “bystander” damage initiates host NLRP3
... Complement mediated phagocytosis by macrophages induces the release of IL-1β and IL-18. To study the effect of phagocytosis on inflammasome activation by macrophages, a variety of complement activating particles were added to LPS-primed murine macrophages, and the release of IL-1β was measured in su ...
... Complement mediated phagocytosis by macrophages induces the release of IL-1β and IL-18. To study the effect of phagocytosis on inflammasome activation by macrophages, a variety of complement activating particles were added to LPS-primed murine macrophages, and the release of IL-1β was measured in su ...
Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.