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Immunology: Specific Immunity
Immunology: Specific Immunity

... cells to attack an infection • T lymphocytes either kill cells directly or recruit macrophages to kill cells directly ...
Therapy of chronic lymphocytic leukemia with purine - hem
Therapy of chronic lymphocytic leukemia with purine - hem

... B-cell chronic lymphocytic leukemia (CLL) is a clonal hematopoietic disorder characterized by proliferation and accumulation of small lymphocytes. It is the most common form of leukemia in North America and Europe. The management of CLL is determined by the stage and activity of the disease. Several ...
Q1. Use the information in the passage and your
Q1. Use the information in the passage and your

... Herpes viruses cause cold sores and, in some cases, genital warts. Scientists are well on the way to producing an antibody which will counteract herpes infection. This antibody works by sticking to the virus and blocking its entry into cells. It has proved very effective in animal tests. ...
Bozeman Video Guide - Cell Communication
Bozeman Video Guide - Cell Communication

... 1) List the 3 analogies Mr. Anderson gives about communication, then describe the 3 ways cell communicate correspond to these analogies Analogy ...
presentation
presentation

... The Immune system is made up of cells and tissues. What makes the immune system so remarkable is its ability to recognize between self and non-self. ...
LYMPHATIC SYSTEM AND IMMUNITY
LYMPHATIC SYSTEM AND IMMUNITY

... enough to stop viruses, bacteria, and fungi.  If this is not enough, the 3rd line must act ...
BC3-1
BC3-1

... site for nasty reactions (oxidation) ie breakdown of products that yield dangerous hydrogen peroxide newly made proteins and lipids are modified and sorted for transport to other parts of cell ...
Lecture-6-ANTIBODY-STRUCTURE-AND
Lecture-6-ANTIBODY-STRUCTURE-AND

... together, e.g. microbial cell surface proteins. In this case the binding is much greater than the affinity of a single antibody-antigen bond and is called the avidity. Asilmi 06 - B CELLS AND ANTIBODIES ...
Document
Document

... • Immature B cells express membrane IgM • Mature B cells express membrane IgM and IgD = BCR and are able to respond to antigen in peripheral ...
Any antibody binds to only a portion of the
Any antibody binds to only a portion of the

... as killed mycobacteria and LPS, that engage TLRs  What are the differences between Adjuvant and carrier?  do not form stable linkages with the immunogen  adjuvants are needed primarily for initial immunizations, whereas carriers are required to elicit not only primary but also subsequent response ...
Adaptive or acquired immune system
Adaptive or acquired immune system

... 5. Alternate complement pathway – cascade of serum proteins that are activated by bacterial cell wall components 2. Adaptive or acquired immune system:  Found only in vertebrates (fish, amphibians, birds and mammals), Must be induced to be active against infections or tumors.  Antigen-specific – a ...
A1984SW52500002
A1984SW52500002

... I showed that the lg+ lymphocytes were B cells whereas the Ig– lymphocytes were T cells. The paper has been widely cited, I suspect, because it was the first direct demonstration that B cells but not T cells have detectable Ig on their surfaces. Since the publication of this paper, the presence of s ...
NOGG_Instruction
NOGG_Instruction

... 100 μl ...
17. The Immune Response
17. The Immune Response

... How the body recognizes harmful antigens (see Fig.7, p.468)  T cells scout the body in search of foreign invaders  The macrophages attack invaders and destroy them, but this doesn’t destroy the antigen markers, they are pushed toward the cell membrane of the macrophage  Pressing the antigens into ...
InfectiousDisease
InfectiousDisease

... Macrophages identifies a pathogen via the antigen Macrophage partially digests pathogen, but displays part of it on its cell membrane (“antigen presentation”) so that circulating leukocytes can recognize and become activated A specific antigen type is identified by leukocytes called helper–T cells ( ...
B cell
B cell

... ·After termination of immune response, the cell memories the Ag. ·When reinvaded by the same Ag, Immune response is more short. ...
Immunity
Immunity

... – The ability of the body to fight infection and/or foreign invaders by producing antibodies or killing infected cells. • Immune System – The system in the body consisting of numerous components that are responsible for maintaining homeostasis by recognizing harmful from non-harmful organisms and pr ...
Word version
Word version

... Pregnant animals produce antibodies which are moved from the bloodstream to the colostrum (first milk). It is very important that newborn animals are given colostrum as their first feed because they can absorb antibodies from the gut into the blood stream at this stage. The colostrum will only conta ...
Student factsheet for this topic
Student factsheet for this topic

... Pregnant animals produce antibodies which are moved from the bloodstream to the colostrum (first milk). It is very important that newborn animals are given colostrum as their first feed because they can absorb antibodies from the gut into the blood stream at this stage. The colostrum will only conta ...
Slide 1
Slide 1

... Brain:primary lymphoma in AIDS: ...
Nanotechnology & Nanobiotechnology
Nanotechnology & Nanobiotechnology

... specificity. They are attached to a drug in order to guide it to a specific cell. For example, cancer drugs can be attached to monoclonal antibodies made against tumour cells, which helps the drug target only tumour cells. This reduces the toxic effects of cancer drugs. ...
Blood and Immunity Review
Blood and Immunity Review

... 1. The ability to fight disease will increase due to antibodies received from the pathogen. 2. The ability to fight disease caused by the pathogen will increase due to antibody production. 3. The ability to produce antibodies will decrease after the vaccination. 4. The ability to resist most types o ...
BSC 361
BSC 361

... This signals the presence of extracellular infecting agents. Antibody structure Several kinds of antibodies but they have basic structures Y shaped with two heavy and two light chains Fab fragment binds antigen Fc fragment interacts with host cell Fab regions vary greatly and allows for a huge numbe ...
PDF datasheet
PDF datasheet

... See vial label ...
Diagnostics 1
Diagnostics 1

... 3. Give examples of types of substance that are typically identified diagnostically by means of antibodies. 4. Explain the use of secondary antibodies in detection. 5. Describe the advantages in different situations of the following types of detection system: enzyme-linked antibodies, radioactively ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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