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The Innate Immune Response PowerPoint
The Innate Immune Response PowerPoint

... 1- non-inflammatory reaction (body’s static defenses) skin, gastric pH, lysozyme in tears, saliva, mucous 2- local inflammation promotes migration of phagocytes and plasma protein into infected tissues The phagocytes respond to surface structures present in large groups of microorganisms (peptidogca ...
File
File

... • Helper T cells • Cytotoxic T cells– attack and destroy invading agent or antigen • Suppressor T Cells– Inhibit or terminate activities of killer cells, plasma cells or T helper cells when their activities are no more needed ...
Immunity and Disease
Immunity and Disease

... • Molecules that are foreign to your body are called antigens. • When your body detects antigens, killer T cells are formed and they release enzymes that target antigens. Helper T cells are also released to stimulate antibody production. • Antibodies attack specific antigens. Some antigens have a me ...
(4) Adaptive Immune System and the Humoral Immune Response
(4) Adaptive Immune System and the Humoral Immune Response

... Artificial active immunity- (vaccine) person is given inactive parts of the pathogen so that memory cells are made. Exposure to the pathogen does not cause the disease. Natural passive immunity- AB in breast milk and the antibodies of a pregnant woman cross the placenta to her fetus. Lasts a few wee ...
SLE (systemic lupus erythematosus)
SLE (systemic lupus erythematosus)

... ribonucleoprotein particle,which contains several different molecules. Patients often produce autoantibodies against each of these different components. What is thereason for the production of this variety of autoantibodies, and what type of failure in tolerance could be responsible for autoantibody ...
A1982PC81600001
A1982PC81600001

... that the spleen has all the necessary immunologic machinery), but transferred thymus cells plus antigen were inert. “The important experiment involved pure serendipity. We felt that the transferred thymus cells might be either too immature or too ‘sluggish’ to respond, so we gave the recipients thym ...
Lecture 4: Host Response to Infection
Lecture 4: Host Response to Infection

... species in amino acid sequence—and therefore shape Antibodies bind antigens by the variable regions The variation in shape is responsible for differences in specificity of different antibody species Continued ...
Scientific Glossary
Scientific Glossary

... Macrophage-activating factor (MAF): Actually several lymphokines, including interferon, released by activated T cells, which together induce activation of macrophages, making them more efficient in phagocytosis and cytotoxicity. Major histocompatibility complex (MHC): A cluster of genes on chromosom ...
Physiology Lecture 10
Physiology Lecture 10

... A person may be type A (with only A antigens), type B (with only B antigens), type AB (with both A and B antigens), or type O (with neither A nor B antigens). Each person inherits two genes (one from each parent) that control the production of the ABO antigens. The genes for A or B antigens are dom ...
Unit 10 p4
Unit 10 p4

... a disease, survives, and therefore, acquires immunity  ARTIFICIALLY ACQUIRED ACTIVE IMMUNITY: **A VACCINE consists of bacteria or viruses that have been _______ so they a cannot cause a serious infection; or could include a toxoid or toxin that has been chemically altered to destroy its toxic effec ...
Virus Notes - ScienceCo
Virus Notes - ScienceCo

... antigen. The purpose of these antibodies is to link viruses together into a large mass known as agglutination. This makes the entire complex much too large to enter any cell and also makes it easier for phagocytes to engulf the pathogens. o B-cells contain genes that are constantly rearranging so th ...
The immune system protects the body from disease.
The immune system protects the body from disease.

... genes are randomly selected and combined to form the heavy and light chains that make antibodies. ...
Immune System
Immune System

... weak or dead pathogen so that an immune response is provoked which makes antibodies and memory cells • Antigen – substance that provokes an immune response – Pathogen – a disease causing organism – Allergen – an otherwise harmless antigen ...
Chapter 15 Cellular Mediated immunity 1. Define immunity providing
Chapter 15 Cellular Mediated immunity 1. Define immunity providing

... d. TH1 and TH2 cells e. natural and artificial immunity f. T-dependent and T-independent antigens g. CD4 and CD8 3. Classify the following examples of immunity as naturally acquired active immunity, naturally acquired passive immunity, artificially acquired active immunity, or artificially acquired ...
Document
Document

... The T cell Receptor - is homologous to antibody. - forms by gene rearrangement. - varies from one T cell to another. but it - is always membrane-bound. - binds to peptides fragments of antigens These must be held on a cell surface by an MHC protein. ...
Human Saliva Amylase Alpha
Human Saliva Amylase Alpha

... oligosaccharides and polysaccharides. They catalyze the first step in digestion of dietary starch and glycogen. Alternative splicing results in multiple transcript variants encoding the same protein. Salivary Amylase is a digestive enzyme secreted by salivary glands, it consists of a single polypept ...
Schneider1
Schneider1

... Stability is an expected problem. ...
self and non
self and non

...  Process by which the body utilizes WBCs and chemicals to provide immediate protection from infection and foreign substances ...
Immunology 3 – Innate Immunity
Immunology 3 – Innate Immunity

... Superoxide anion Hydrogen peroxide Singlet oxygen Hydroxyl radical Reactive nitrogen intermediates Nitric oxide ...
Primary and Secondary Immune Response: Lectuer-9
Primary and Secondary Immune Response: Lectuer-9

... 4. Size and Number of doses 5. Multiple antigens 6. Adjuvant 7. Immunosuppressive agent Cellular Immune Response: The term cell rnediated immunity refers to the specific immune responses that do not involve antibodies, induction of cell mediated immune response (CMI) consists of specifically sensiti ...
Practice Exam 4 - Montgomery College
Practice Exam 4 - Montgomery College

... 2) Which of the following is NOT considered entry via the parenteral route? A) Injection B) Bite C) Surgery D) Hair follicle E) Skin cut 3) Which of the following does NOT contribute to the virulence of a pathogen? A) Numbers of microorganisms that gain access to a host B) Cell wall C) Toxins D) Enz ...
1) Siderophores are bacterial proteins that compete with animal A
1) Siderophores are bacterial proteins that compete with animal A

... 2) Which of the following is NOT considered entry via the parenteral route? A) Injection B) Bite C) Surgery D) Hair follicle E) Skin cut 3) Which of the following does NOT contribute to the virulence of a pathogen? A) Numbers of microorganisms that gain access to a host B) Cell wall C) Toxins D) Enz ...
Document
Document

... There are two general types of immune response: native and acquired. Immunity may be either humoral or cell-mediated. The antibodies secreted by B cells are called immunoglobulins. Antibodies make antigens more visible to the immune system in three ways: by acting as opsonins, by making antigens clu ...
10.8 Immune surveillance and cancer
10.8 Immune surveillance and cancer

... 1. antigenic modulation (by capping with antibodies, masking by glycocalyx coat, shedding) 2. non-antigenic subclone of cells (which may arise during tumor progression) ...
Ch 11 Blood Analysis Vocabulary
Ch 11 Blood Analysis Vocabulary

... 5. Serum – a liquid that separates from clotted blood 6. Antigen – foreign substance or cell in the body that is capable of causing disease or reacts with antibodies. The presence of antigens triggers an immune response, usually antibody production. 7. Agglutinate – an allergic reaction, generally a ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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