• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
ch03dwcr
ch03dwcr

... to the tumor site and retrieve it for analysis. The concept of the "sentinel" node, or the first node to drain the area of the cancer, allows a more accurate staging of the cancer, and leaves unaffected nodes behind to continue the important job of draining fluids. NYT ...
Chemical reactions of amino acids:
Chemical reactions of amino acids:

... reaction and Edman reaction}, these used to detect the first amino acid in primary structure of protein.  Some peptides of amino acids are due to both – NH2 and – COOH group together like chelating of amino acid with certain heavy metals and other ions like Cu2+, Co2+,Mn2+ and ...
Comparison of Trypsin Immobilization Techniques With or Without a
Comparison of Trypsin Immobilization Techniques With or Without a

... proteomics, fast enzymatic digestions and efficient analysis techniques like capillary electrophoresis (CE), liquid chromatography (HPLC) and mass spectrometry (MS) are essential. Immobilized enzymes, defined as enzymes with restricted mobility, offer technical and economical advantages over soluble ...
Cellular and Molecular Biology (HTH SCI 1I06) Legacy Summary
Cellular and Molecular Biology (HTH SCI 1I06) Legacy Summary

... What was the hardest part of this class? The content presented in this class can be challenging at certain times, and we found ourselves struggling the most with the types of agonism taught in Chari’s Thursday lectures. Most of us had a very particular idea of what an agonist is and does - binding ...
Lab 2
Lab 2

... • Osmotic pressure is the hydrostatic pressure produced by a difference in concentration between solutions on the two sides of a surface such as a semipermeable membrane. • An isotonic environment for a cell is created when the solution outside of the cell is isotonic (having equal accent )with the ...
Practice of Radiation Therapy
Practice of Radiation Therapy

... relatives ( used to treated Giardiasis) These drugs have long tissue halflives and diffuse into tissue further than oxygen ...
Protein - DNA interaction in chromatin
Protein - DNA interaction in chromatin

... DNA has three primary attributes that allow it to be far better than RNA at encoding genetic information. First, it is normally double-stranded, so that there are a minimum of two copies of the information encoding each gene in every cell. Second, DNA has a much greater stability against breakdown t ...
Cadherin, Pan, Rabbit Polyclonal Antibody
Cadherin, Pan, Rabbit Polyclonal Antibody

... (Ab 1:200 for 30 min at RT with LV UltraVision) • [Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.] ...
2.3 Carbon-Based Molecules
2.3 Carbon-Based Molecules

... •  Phospholipids make up all cell membranes. –  Polar phosphate head (hydrophilic) –  Nonpolar fatty acid tails (hydrophobic) Phospholipid ...
Lesson Plan - Colorado FFA
Lesson Plan - Colorado FFA

... Ask each team to have a representative from their group answer each question. Tell them they will have 15 seconds to give the correct answer. Keep track of the points and give out a small prize (candy, points) to the winning team. Start by presenting slide#23with directions to the class. Then show t ...
Cells and Tissues PPT
Cells and Tissues PPT

... building block of all human things Smallest unit capable of life by itself ...
Phospho-Src Family (Tyr416) Antibody
Phospho-Src Family (Tyr416) Antibody

... signaling from multiple cell surface receptors such as the B cell antigen receptor (BCR) and CD40 (4). Lck is essential for T-lymphocyte activation and differentiation (5,6). Phosphorylation of the carboxy-terminal Tyr505 downregulates Lck activity, while phosphorylation at Tyr394 leads to an increa ...
Anti-Vinculin antibody
Anti-Vinculin antibody

... interactions between the head and tail domains prevent detectable binding to most of its ligands. It takes on an 'active' conformation after cooperative and simultaneous binding of two different ligands. This activation involves displacement of the head-tail interactions and leads to a significant a ...
Cell Cycle
Cell Cycle

...  The cell membrane is pinched into two nearly equal parts = cleavage ...
protein synthesis
protein synthesis

... 1 codon codes for 1 amino acid (A.A.) There are 4 bases (A, T, C, G) Thus 4 3 (64) possible combinations of codons There are 20 amino acids Code is redundant (2 or more codons code for same amino acid) but not ambiquous (no codon codes fro more than 1 amino acid) ...
Cell Cycle Notes
Cell Cycle Notes

...  The cell membrane is pinched into two nearly equal parts = cleavage ...
biomolecules
biomolecules

... and oxygen, and a side chain (labeled R on amino acid diagrams). The side chain is different for each of the twenty amino acids. Some side chains are hydrophobic, while others are hydrophilic, or water-soluble. Some side chains are charged, while others are neutral. The different properties of the s ...
gene expression - cloudfront.net
gene expression - cloudfront.net

... double helix. During transcription, only one DNA strand serves as a template (a guide or model) for RNA synthesis. The other strand remains dormant. 2. The enzyme moves along the DNA strand and “reads” the nucleotides one by one, similar to the process in DNA replication. The enzyme selects free-flo ...
Post-translational modifications on human cell expressed
Post-translational modifications on human cell expressed

... Most proteins undergo post-translational modification (PTM), which can alter their physical and chemical properties (e.g., MW, pI, folding, stability, activity, antigenicity, and function). The presence or absence of PTMs may be significant to both the activity and longevity of the protein in a biolog ...
Biology Keystone Supplemental Packet
Biology Keystone Supplemental Packet

... Golgi apparatus – modifies, sorts, and packages proteins from the endoplasmic reticulum for storage in the cell or secretion out of the cell Lysosomes – small organelles containing enzymes used in the breakdown of lipids, carbohydrates, and proteins; acts as the “clean up” crew in the cell removing ...
AP® BIOLOGY 2010 SCORING GUIDELINES (Form B)
AP® BIOLOGY 2010 SCORING GUIDELINES (Form B)

... In part (a) 4 points were earned. Three points were earned for the description of a frameshift mutation, how the new codons would code for different amino acids, and how the mutation would affect the protein by changing the amino acid sequence/primary structure. Another point was earned for describi ...
A1981LC33100001
A1981LC33100001

... proteins of the myelin sheath in the PNS. By contrast, connective tissues contain relatively little tryptophan and are unstained. At the time, the method added a useful amino acid stain to back up those for tyrosine, cystine, and arginine. 2 The relative staining intensity for these various amino ac ...
Versatile Bioassays Using Surface Plasmon Resonance
Versatile Bioassays Using Surface Plasmon Resonance

... Surface Plasmon Resonance (SPR) spectroscopy from a planar gold film is an important technique for studying biomolecular interactions on solid-liquid interface. Noble metal nanoparticles, i.e. gold nanoparticles (AuNPs), have strong interactions with light to generate localized SPR (LSPR) that leads ...
Identify and Destroy Cancer Cells Using Nano Technology
Identify and Destroy Cancer Cells Using Nano Technology

... functioning cells which are essential to one‟s well-being. In general, the most common methods used for the cancer treatment are ...
Plant proteomics workshop_final072114
Plant proteomics workshop_final072114

... http://onlinelibrary.wiley.com/doi/10.1002/mas.21365 ...
< 1 ... 96 97 98 99 100 101 102 103 104 ... 262 >

Cell-penetrating peptide



Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular uptake of various molecular cargo (from nanosize particles to small chemical molecules and large fragments of DNA). The ""cargo"" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions. The function of the CPPs are to deliver the cargo into cells, a process that commonly occurs through endocytosis with the cargo delivered to the endosomes of living mammalian cells.CPPs hold great potential as in vitro and in vivo delivery vectors for use in research and medicine. Current use is limited by a lack of cell specificity in CPP-mediated cargo delivery and insufficient understanding of the modes of their uptake.CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids such as lysine or arginine or has sequences that contain an alternating pattern of polar/charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or amphipathic, respectively. A third class of CPPs are the hydrophobic peptides, containing only apolar residues, with low net chargeor have hydrophobic amino acid groups that are crucial for cellular uptake.The first CPP was discovered independently by two laboratories in 1988, when it was found that the trans-activating transcriptional activator (TAT) from human immunodeficiency virus 1 (HIV-1) could be efficiently taken up from the surrounding media by numerous cell types in culture. Since then, the number of known CPPs has expanded considerably and small molecule synthetic analogues with more effective protein transduction properties have been generated.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report