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Protein Synthesis Reading
Protein Synthesis Reading

... protein, which in turn codes for a trait. Hence you hear it commonly referred to as the gene for baldness or the gene for blue eyes. Meanwhile, DNA is the chemical that genes and chromosomes are made of. DNA is called a nucleic acid because it was first found in the nucleus. We now know that DNA is ...
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... As shown in Figure 1, DNA looks like an incredibly long twisted ladder. This shape is called a double helix. The sides of the ladder are a linked chain of alternating sugar and phosphate molecules (called the backbone). The rungs connected to the sugar molecules are known as bases. ...
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... (mRNA) copies of genes. This process is called transcription and is the first  step in protein synthesis.  Genes are made of DNA and contain the codes for  making proteins.  Since DNA is unable to leave the nucleus, RNA Pol II makes  an mRNA copy that can leave the nucleus. Ribosomes then attach to  ...
Biological Basis PDF worksheet - UNC
Biological Basis PDF worksheet - UNC

... of very long chains of simpler units. However, the components, shapes, and functions of nucleic acids differ significantly from those of proteins. There are two basic varieties of nucleic acids: DNA (deoxyribonucleic acid ) and RNA (ribonucleic acid ). Both play critical roles in the production of p ...
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Gene Expression and DNA Replication

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... DIRECTIONS: Write the letter of the BEST ANSWER beside each number of each the question. 1. Genes for medically important proteins can be cloned and inserted into bacteria, as shown in the diagram on the right. Why can bacteria recognize a human gene and then produce a human protein? A. DNA replicat ...
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... B. The number of subunits in a DNA molecule C. The sequence of subunits in a protein molecule D. The number of subunits in a protein molecule 4. Humans, butterflies, and trees are all living things. In which of these organisms would you find DNA molecules? A. Only in humans B. Only in humans a ...
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... called nucleotides, which are held together by a backbone made of sugars and phosphate groups. This backbone carries four types of molecules called bases and it is the sequence of these four bases that encodes information. The major function of DNA is to encode the sequence of amino acid residues in ...
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... RNA to be the same as that found in double-stranded DNA, the hereditary information of all living cells. In double-stranded DNA, the molar ratio of purine to pyrimidine bases is equal to 1 because As pair with Ts, and Cs pair with Gs. Because the genetic material of HIV is single-stranded RNA, base- ...
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... 29. In a PCR reaction, the highest temperature step (typically ~ 95oC) is necessary for a. DNA replication b. Primer annealing c. Denaturing double stranded DNA 30. Which of the following properties make TAQ polymerase particularly useful for PCR? a. It is very cheap b. It cuts double stranded DNA c ...
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... combination of genes that is more successful than his/her parents or siblings. • This will make the individual ‘more fit’ and therefore more likely to survive in their environment and pass on their DNA to future ...
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Deoxyribozyme



Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of catalyzing specific chemical reactions, similar to the action of other biological enzymes, such as proteins or ribozymes (enzymes composed of RNA).However, in contrast to the abundance of protein enzymes in biological systems and the discovery of biological ribozymes in the 1980s,there are no known naturally occurring deoxyribozymes.Deoxyribozymes should not be confused with DNA aptamers which are oligonucleotides that selectively bind a target ligand, but do not catalyze a subsequent chemical reaction.With the exception of ribozymes, nucleic acid molecules within cells primarily serve as storage of genetic information due to its ability to form complementary base pairs, which allows for high-fidelity copying and transfer of genetic information. In contrast, nucleic acid molecules are more limited in their catalytic ability, in comparison to protein enzymes, to just three types of interactions: hydrogen bonding, pi stacking, and metal-ion coordination. This is due to the limited number of functional groups of the nucleic acid monomers: while proteins are built from up to twenty different amino acids with various functional groups, nucleic acids are built from just four chemically similar nucleobases. In addition, DNA lacks the 2'-hydroxyl group found in RNA which limits the catalytic competency of deoxyribozymes even in comparison to ribozymes.In addition to the inherent inferiority of DNA catalytic activity, the apparent lack of naturally occurring deoxyribozymes may also be due to the primarily double-stranded conformation of DNA in biological systems which would limit its physical flexibility and ability to form tertiary structures, and so would drastically limit the ability of double-stranded DNA to act as a catalyst; though there are a few known instances of biological single-stranded DNA such as multicopy single-stranded DNA (msDNA), certain viral genomes, and the replication fork formed during DNA replication. Further structural differences between DNA and RNA may also play a role in the lack of biological deoxyribozymes, such as the additional methyl group of the DNA base thymidine compared to the RNA base uracil or the tendency of DNA to adopt the B-form helix while RNA tends to adopt the A-form helix. However, it has also been shown that DNA can form structures that RNA cannot, which suggests that, though there are differences in structures that each can form, neither is inherently more or less catalytic due to their possible structural motifs.
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