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Slide 1
Slide 1

... 2. Medicinal 3. Forensics ...
DNA
DNA

... Supply of the four nucleotides DNA polymerase (enzyme involved in DNA replication) Primers ...
File
File

... 2.6 Thus in a pedigree in which a sex-linked mutation is segregating, the mutation is inherited through the male line and the resultant disorder present in every generations [ ...
genes
genes

... the same time. Different cells perform different functions and therefore need different proteins ...
genet_174(2)_cover 4.qxd
genet_174(2)_cover 4.qxd

... Elie S. Dolgin and Brian Charlesworth In sexual populations, transposable elements (TEs) can be contained by purifying selection. However, an asexual population could potentially be driven to extinction by an unchecked proliferation of TEs. Here the authors provide a theoretical framework for analyz ...
ENCODE Project - HudsonAlpha Institute for Biotechnology
ENCODE Project - HudsonAlpha Institute for Biotechnology

... identifying context and meaning for the genome. ENCODE has provided a deep and high-quality description of genomic activity that will be useful throughout many biological and disease research areas. The next step is to figure out how the various players in this regulatory symphony interact. For exam ...
Examination IV Key
Examination IV Key

... 13. Sticky ends generated by cutting DNA with a restriction endonuclease are useful because those sticky ends ...
Genetic Engineering Techniques
Genetic Engineering Techniques

... the  DNA  at  a  certain  recognizable  sequence.  The  same  enzyme  is  then  used  to  treat   the  DNA  sequence  to  be  engineered  into  the  bacteria;  this  procedure  creates  "sticky   ends"  that  will  fuse  together  if ...
MODULE 2
MODULE 2

... - INTRON derived from the term intragenic region removed by RNA splicing. - EXON nucleic acid in the mature form of an RNA molecule - PROMOTER region that facilitates transcription - REPRESSOR prevents gene expression ...
Note: all of these sentences are true.
Note: all of these sentences are true.

... 24.Type I DNA topoisomerases, cut one strand of the DNA duplex and relax negative supercoiled DNA only. 25.Type II DNA topoisomerases, cut both strands of a DNA duplex, can relax either negatively or positively supercoild DNA molecules. 26.DNA gyrase is a type II topoisomerase found in bacteria and ...
Exam 2
Exam 2

... during meiosis. When adjacent segregation occurs (50% of the time), all chromosomes will have deletions or duplications The progeny resulting from gametes carrying these defective chromosomes most likely will not develop. Thus, the individual appears semisterile because 50% of gametes carry defectiv ...
Transcription and Translation Exercise
Transcription and Translation Exercise

... 7. The allele of the gene above is dominant and codes for red kernel pigment (it is designated as R). Another allele of this gene, the r allele (which is recessive), codes for white kernel pigment and is the result of a mutation in the R allele. In the r allele, the second nucleotide (base) in the s ...
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File

... have two polypeptides, but those polypeptides exist in two slightly different forms that differ from each other only slightly. People that are heterozygous produce both forms of polypeptides and others produce one form or the other. Consider the case of an individual that is heterozygous for this ge ...
Chapter 21 (part 1) - Nevada Agricultural Experiment
Chapter 21 (part 1) - Nevada Agricultural Experiment

... Mitochondrial RNA Mitochondrial gene Mitochondria polymerase transcripts Chloroplast RNA polymerase ...
Transcription - OpenStax CNX
Transcription - OpenStax CNX

... Once a gene is transcribed, the prokaryotic polymerase needs to be instructed to dissociate from the DNA template and liberate the newly made mRNA. Depending on the gene being transcribed, there are two kinds of termination signals, but both involve repeated nucleotide sequences in the DNA template ...
Nabil Bashir 10-21
Nabil Bashir 10-21

... - The same idea as heat shock promoter ,, so it's another example for the promoters that differ in the -10 & -35 regions - this promoter also have a specific job on certain conditions ,, here the condition is : lack of nitrogen in the cells •• once the bacteria finds no nitrogen source some factors ...
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ORLANDO BIOLOGY ~ LESSON PLANS Competencies for 21st
ORLANDO BIOLOGY ~ LESSON PLANS Competencies for 21st

...  That the processes of transcription and translation use the information from the DNA to make specific proteins.  That control of transcription is on the gene level and is affected by many factors such as the environment and the stage of life.  That a change (mutation) in the DNA sequence (such a ...
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Lesson Overview

... Base pairing in the double helix explained how DNA could be copied, or replicated, because each base on one strand pairs with only one base on the opposite strand. Each strand of the double helix has all the information needed to reconstruct the other half by the mechanism of base pairing. Because e ...
The Major Transitions in Evolution
The Major Transitions in Evolution

... • Traditions are defined as behaviour patterns that are customary or habitual in at least one site but absent elsewhere. • Transmission is attributed to social learning on the basis of a complex of circumstantial evidence, ranging from intense observation by juveniles to distributions inconsistent w ...
The Major Transitions in Evolution
The Major Transitions in Evolution

... • Traditions are defined as behaviour patterns that are customary or habitual in at least one site but absent elsewhere. • Transmission is attributed to social learning on the basis of a complex of circumstantial evidence, ranging from intense observation by juveniles to distributions inconsistent w ...
EPIGENETICS Textbook
EPIGENETICS Textbook

... – Define cell identity and function – maintain differentiated state, – Complexes highly conserved in plants and animals; 1st described in Drosophila • Trithorax Group (trxG) maintains active transcription • Polycomb Group (PcG) maintains transcription repression ...
GPVEC 2008 Biotech part 1
GPVEC 2008 Biotech part 1

... agriculturally important organisms by selection and breeding. An example of traditional agricultural biotechnology is the development of disease-resistant wheat varieties by cross-breeding different wheat types until the desired disease resistance was present in a resulting new variety. ...
Study Guide
Study Guide

Examination 3
Examination 3

... - Telomerase • What is transcription? What is translation? o Transcription – Figure 17.26- taking DNA and making RNA (transcribed to mRNA) o Translation- taking RNA to proteins (mRNA is translated into protein with help of rRNA and ...
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Deoxyribozyme



Deoxyribozymes, also called DNA enzymes, DNAzymes, or catalytic DNA, are DNA oligonucleotides that are capable of catalyzing specific chemical reactions, similar to the action of other biological enzymes, such as proteins or ribozymes (enzymes composed of RNA).However, in contrast to the abundance of protein enzymes in biological systems and the discovery of biological ribozymes in the 1980s,there are no known naturally occurring deoxyribozymes.Deoxyribozymes should not be confused with DNA aptamers which are oligonucleotides that selectively bind a target ligand, but do not catalyze a subsequent chemical reaction.With the exception of ribozymes, nucleic acid molecules within cells primarily serve as storage of genetic information due to its ability to form complementary base pairs, which allows for high-fidelity copying and transfer of genetic information. In contrast, nucleic acid molecules are more limited in their catalytic ability, in comparison to protein enzymes, to just three types of interactions: hydrogen bonding, pi stacking, and metal-ion coordination. This is due to the limited number of functional groups of the nucleic acid monomers: while proteins are built from up to twenty different amino acids with various functional groups, nucleic acids are built from just four chemically similar nucleobases. In addition, DNA lacks the 2'-hydroxyl group found in RNA which limits the catalytic competency of deoxyribozymes even in comparison to ribozymes.In addition to the inherent inferiority of DNA catalytic activity, the apparent lack of naturally occurring deoxyribozymes may also be due to the primarily double-stranded conformation of DNA in biological systems which would limit its physical flexibility and ability to form tertiary structures, and so would drastically limit the ability of double-stranded DNA to act as a catalyst; though there are a few known instances of biological single-stranded DNA such as multicopy single-stranded DNA (msDNA), certain viral genomes, and the replication fork formed during DNA replication. Further structural differences between DNA and RNA may also play a role in the lack of biological deoxyribozymes, such as the additional methyl group of the DNA base thymidine compared to the RNA base uracil or the tendency of DNA to adopt the B-form helix while RNA tends to adopt the A-form helix. However, it has also been shown that DNA can form structures that RNA cannot, which suggests that, though there are differences in structures that each can form, neither is inherently more or less catalytic due to their possible structural motifs.
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