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Isolation of the plc1 gene from the fission yeast
Isolation of the plc1 gene from the fission yeast

... Conjugation between two haploid cells of the fission yeast Schizosaccharomyces pombe involves a communication system based on the reciprocal action of diffusible mating pheromones (reviewed in [l]). Binding of the pheromones to their specific receptors on the surface of the target cell initiates a s ...
The Three-Dimensional Structure of Proteins
The Three-Dimensional Structure of Proteins

... implemented by the U.S. Department of Labor’s Employment and Training Administration. The solution was created by the grantee and does not necessarily reflect the official position of the U.S. Department of Labor. The Department of Labor makes no guarantees, warranties, or assurances of any kind, ex ...
Proteases: Hydrolysis of Peptide Bonds
Proteases: Hydrolysis of Peptide Bonds

... Fertilization; specification of dorsoventral polarity; Retroviral protease cleavage of polyproteins procollagen to collagen for self-assembly ...
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Carbohydrates Lipids (Fats) Proteins Nucleic Acids (DNA, RNA)

gln.val.tyr.ala lys.arg.glu.trp met.his.leu.asp cys.pro.gly.asn F-A-D
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... In the Edman degradation of a peptide, the peptide first reacts with phenylisothiocyanate under ______________ (acid or alkaline?) conditions; the amino acid at the _____________ (amino terminal or carboxyl terminal?) is then removed in _______________ (acid or alkaline?) conditions, and the resulti ...
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Date ______ Period

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Proteolysis



Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.
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