Amino Acid Sequence Homology of Coat Proteins as a Basis for
... When the 136 possible comparisons of complete coat protein sequences of the 17 strains of eight distinct viruses (Table 1) are graphed as a frequency distribution (Fig. 1) the results clearly reveal a bimodal distribution of sequence homologies. In almost all cases the sequence homology between dist ...
... When the 136 possible comparisons of complete coat protein sequences of the 17 strains of eight distinct viruses (Table 1) are graphed as a frequency distribution (Fig. 1) the results clearly reveal a bimodal distribution of sequence homologies. In almost all cases the sequence homology between dist ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... treatment of schistosomiasis, helminthiasis and most intestinal protozoa infections. However, none of the compounds covers the whole parasite spectrum and they were mostly developed decades ago [8], [9], [10]. The main anthelminthic drugs are praziquantel for the treatment of trematodes and cestodes ...
... treatment of schistosomiasis, helminthiasis and most intestinal protozoa infections. However, none of the compounds covers the whole parasite spectrum and they were mostly developed decades ago [8], [9], [10]. The main anthelminthic drugs are praziquantel for the treatment of trematodes and cestodes ...
A RapidMiner framework for protein interaction extraction
... “In the shaA mutant, sigma(H)-dependent expression of spo0A and spoVG at an early stage of sporulation was sensitive to external NaCl.” This sentence contains 4 protein names, namely shaA, sigma(H), spo0A and spoVG. The first step of the PPI extraction task is to identify these names in the text. As ...
... “In the shaA mutant, sigma(H)-dependent expression of spo0A and spoVG at an early stage of sporulation was sensitive to external NaCl.” This sentence contains 4 protein names, namely shaA, sigma(H), spo0A and spoVG. The first step of the PPI extraction task is to identify these names in the text. As ...
Dr. John Perozich's Full CV
... Katie Kirrane in which 41 protein sequences of insulysins, also called insulin-degrading enzymes which may play important roles in diabetes and Alzheimer’s disease, were aligned to elucidate structural, functional and phylogenetic relationships in the enzyme. Comparative Analysis of Pyruvate Kinase ...
... Katie Kirrane in which 41 protein sequences of insulysins, also called insulin-degrading enzymes which may play important roles in diabetes and Alzheimer’s disease, were aligned to elucidate structural, functional and phylogenetic relationships in the enzyme. Comparative Analysis of Pyruvate Kinase ...
One 2-fold axis of symmetry
... through 180˚ gives an indistinguishable structure. Thus, there is a 2-fold axis of symmetry, also called a dyad. In haemoglobin we are concerned with a tetramer. (Although there are two different subunits, and , we regard them as practically identical and qualify our statements by referring to ps ...
... through 180˚ gives an indistinguishable structure. Thus, there is a 2-fold axis of symmetry, also called a dyad. In haemoglobin we are concerned with a tetramer. (Although there are two different subunits, and , we regard them as practically identical and qualify our statements by referring to ps ...
Chapter 26
... • Sense that food has arrived in the stomach • Secrete PYY long before chyme reaches the ileum in amounts proportionate to calories consumed • Primary effect is to signal satiety and terminate eating • Signal that ends a meal ...
... • Sense that food has arrived in the stomach • Secrete PYY long before chyme reaches the ileum in amounts proportionate to calories consumed • Primary effect is to signal satiety and terminate eating • Signal that ends a meal ...
Amino Acid Metabolism
... • In certain body tissues, this enzyme catalyzes the oxidative decarboxylation of valine, isoleucine, and leucine yielding CO2, and acyl-CoA derivatives. • Shares ancestry with pyruvate dehydrogenase complex, -KG dehydrogenase complex – another example of gene duplication ...
... • In certain body tissues, this enzyme catalyzes the oxidative decarboxylation of valine, isoleucine, and leucine yielding CO2, and acyl-CoA derivatives. • Shares ancestry with pyruvate dehydrogenase complex, -KG dehydrogenase complex – another example of gene duplication ...
CHAPTER FOUR Pseudomonas aeruginosa INFLUENCED PLANKTONIC AND BIOFILM POPULATIONS BASED UPON
... sessile multicellular communities known as biofilms (Costerton et al., 1987; 1995). The transition to surface-attached (biofilm) growth is known to result in diverse changes in gene expression, which causes the attaching cells to become phenotypically and metabolically distinct from their planktonic ...
... sessile multicellular communities known as biofilms (Costerton et al., 1987; 1995). The transition to surface-attached (biofilm) growth is known to result in diverse changes in gene expression, which causes the attaching cells to become phenotypically and metabolically distinct from their planktonic ...
Block III - Madhya Pradesh Bhoj Open University
... complex proteins of the plants. It is the main constituent of several coenzymes, vitamins (thiamine, biotin, CoA) and ferredoxin. The plants take this element from the soil in the form of calcium and potassium sulphate. Light is the ultimate source of free energy for all life. All biological process ...
... complex proteins of the plants. It is the main constituent of several coenzymes, vitamins (thiamine, biotin, CoA) and ferredoxin. The plants take this element from the soil in the form of calcium and potassium sulphate. Light is the ultimate source of free energy for all life. All biological process ...
Microbiology: A Systems Approach, 2nd ed.
... allows the cell to recover significant amounts of energy – Fermentation: when facultative and aerotolerant anaerobes use only the glycolysis scheme to incompletely oxidize glucose – Aerobic respiration: When oxygen is used as the final electron acceptor at the end of the respiration scheme to produc ...
... allows the cell to recover significant amounts of energy – Fermentation: when facultative and aerotolerant anaerobes use only the glycolysis scheme to incompletely oxidize glucose – Aerobic respiration: When oxygen is used as the final electron acceptor at the end of the respiration scheme to produc ...
Sequence identity and homology
... As a general rule, orthologous proteins tend to perform the same function in different species, while paralogous proteins tend to have diversified somewhat in function. For example, the chymotrypsin serine proteases are orthologous to each other, and they retain not only the same general function (p ...
... As a general rule, orthologous proteins tend to perform the same function in different species, while paralogous proteins tend to have diversified somewhat in function. For example, the chymotrypsin serine proteases are orthologous to each other, and they retain not only the same general function (p ...
Nutritional Requirements and Biosynthetic
... the lipid fraction, separated after hydrolysis by chromatography, have been identified as serine and ethanolamine ;no choline was detected by the phosphomolybdic acid method of Chargaff, Levine & Green (1948).These nitrogenous compounds contained no carbon derived from acetate. Chromatograms of the ...
... the lipid fraction, separated after hydrolysis by chromatography, have been identified as serine and ethanolamine ;no choline was detected by the phosphomolybdic acid method of Chargaff, Levine & Green (1948).These nitrogenous compounds contained no carbon derived from acetate. Chromatograms of the ...
Citrate transporters of Bacillus subtilis Krom, Bastiaan Philip
... while exchange is catalyzed by the monomer as functional unit (41). The oligomeric state of some secondary transporters has been determined. Some were found to be monomers, while others are present in the membrane as higher oligomeric structures. ...
... while exchange is catalyzed by the monomer as functional unit (41). The oligomeric state of some secondary transporters has been determined. Some were found to be monomers, while others are present in the membrane as higher oligomeric structures. ...
SFE1, a Constituent of the Fertilization Envelope
... The fatal consequence of polyspermy was documented by Boveri [1] among others, who reported that fusion of more than one sperm with an egg typically leads to aberrant blastomere cleavage and early embryonic death. Thus, it was realized that a prevention or block to polyspermy must be a fundamental p ...
... The fatal consequence of polyspermy was documented by Boveri [1] among others, who reported that fusion of more than one sperm with an egg typically leads to aberrant blastomere cleavage and early embryonic death. Thus, it was realized that a prevention or block to polyspermy must be a fundamental p ...
Nutritional Requirements and Biosynthetic
... the lipid fraction, separated after hydrolysis by chromatography, have been identified as serine and ethanolamine ;no choline was detected by the phosphomolybdic acid method of Chargaff, Levine & Green (1948).These nitrogenous compounds contained no carbon derived from acetate. Chromatograms of the ...
... the lipid fraction, separated after hydrolysis by chromatography, have been identified as serine and ethanolamine ;no choline was detected by the phosphomolybdic acid method of Chargaff, Levine & Green (1948).These nitrogenous compounds contained no carbon derived from acetate. Chromatograms of the ...
Document
... • Different evolutionary origins, no sequence similarity • Similarities in the reaction mechanisms. Chymotrypsin, subtilisin and carboxypeptidase C have a catalytic triad of serine, aspartate and histidine in common: serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base ...
... • Different evolutionary origins, no sequence similarity • Similarities in the reaction mechanisms. Chymotrypsin, subtilisin and carboxypeptidase C have a catalytic triad of serine, aspartate and histidine in common: serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base ...
Immunophilins and Parvulins. Superfamily of
... endoplasmic reticulum (Stamnes et al., 1991). It is not known if foldase/rotamase activity is essential for these trafficking processes. Other findings suggest that each member of immunophilins may have specific functions that may or may not be related to their function in protein folding process. F ...
... endoplasmic reticulum (Stamnes et al., 1991). It is not known if foldase/rotamase activity is essential for these trafficking processes. Other findings suggest that each member of immunophilins may have specific functions that may or may not be related to their function in protein folding process. F ...
Protein Calorie Malnutrition
... poor utilization of stubstrate • Protein breakdown continues unabated In some burn patients amount of protein catabolized can reach 200 g/d = ~0.5 lb/day lean body mass! Severe protein malnutrition results in as little as 1 week. Repletion of body stores is not achievable until metabolic ...
... poor utilization of stubstrate • Protein breakdown continues unabated In some burn patients amount of protein catabolized can reach 200 g/d = ~0.5 lb/day lean body mass! Severe protein malnutrition results in as little as 1 week. Repletion of body stores is not achievable until metabolic ...
Powerpoint
... leading to DD clustering. FADD ( Fas associated death domain/ Mort 1) binds via its own DD Caspase –8 oligomerisation drives activation through self cleavage Caspase –8 then activates downstream effector caspases like caspase –9 (CED-9 ...
... leading to DD clustering. FADD ( Fas associated death domain/ Mort 1) binds via its own DD Caspase –8 oligomerisation drives activation through self cleavage Caspase –8 then activates downstream effector caspases like caspase –9 (CED-9 ...
Simplification of the genetic code: restricted
... reduced alphabet. In one of the codes, a tRNAAla variant with the Trp anticodon reassigns alanine to an unassigned UGG codon in the Escherichia coli S30 cell-free translation system lacking tryptophan. We confirmed that the efficiency and accuracy of protein synthesis by this Trp-lacking code were c ...
... reduced alphabet. In one of the codes, a tRNAAla variant with the Trp anticodon reassigns alanine to an unassigned UGG codon in the Escherichia coli S30 cell-free translation system lacking tryptophan. We confirmed that the efficiency and accuracy of protein synthesis by this Trp-lacking code were c ...
PROTEIN METABOLISM
... life started, and it doesn’t explain what came before RNA. But as part of the continually growing body of circumstantial evidence that there was a life form before us on this planet, from which we emerged—boy, it’s very strong! —Gerald Joyce, quoted in commentary in Science, 1992 ...
... life started, and it doesn’t explain what came before RNA. But as part of the continually growing body of circumstantial evidence that there was a life form before us on this planet, from which we emerged—boy, it’s very strong! —Gerald Joyce, quoted in commentary in Science, 1992 ...
Microbial Metabolism
... Chemoorganoheterotroph Metabolism Overview: Reduction; e- gain from donor ...
... Chemoorganoheterotroph Metabolism Overview: Reduction; e- gain from donor ...
Problems in Protein Biosynthesis - The Journal of General Physiology
... most stable conformation of its polypeptide chain under physiological conditions. In the second step, called translation, the sequence of four kinds of nucleotides in mRNA serves as the template for ordering the sequence of the 20 kinds of amino acids into a polypeptide chain. The code used in this ...
... most stable conformation of its polypeptide chain under physiological conditions. In the second step, called translation, the sequence of four kinds of nucleotides in mRNA serves as the template for ordering the sequence of the 20 kinds of amino acids into a polypeptide chain. The code used in this ...
Fall 2009 Chem 306 Exam II KEY
... 45. Electrophoresis is a laboratory method a. used to determine enzyme activity b. that allows for the identification of amino acids and proteins. c. that is based on the differential migration of charged species within an electrical field. d. which is used to help diagnose diseases such as sickle ...
... 45. Electrophoresis is a laboratory method a. used to determine enzyme activity b. that allows for the identification of amino acids and proteins. c. that is based on the differential migration of charged species within an electrical field. d. which is used to help diagnose diseases such as sickle ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.