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aptamers04
aptamers04

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... the possibility that nuclear transport may occur via many different pathways. Recently, two members of this family, Crm1 (in yeast and higher eukaryotes) and human CAS were shown to be karyopherins involved in nuclear export (also called exportins; Fornerod et al., 1997b; Kutay et al., 1997b; Stade ...
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... Most viral proteins play multiple roles in the viral life cycle, thereby maximizing the functionality of each individual protein. The large hepatitis B surface protein (LHBs) of the hepatitis B virus (HBV) is a typical case of this (for review, see Ganem, 1996). The LHBs is transcribed from the env ...
Topology and Phosphorylation of Soybean Nodulin
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Advances in affinity purification mass spectrometry of

... mostly used by the splicing field to keep spliceosomal activity intact after cell breakage, and often this was achieved with a pestle and mortar cooled with liquid N2 or a coffee grinder, grinding frozen cell material [22]. In recent years, more sophisticated equipment such as cryomills have been us ...
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Proteolysis



Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.
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