Disruption of Glucocorticoid and Mineralocorticoid Receptor
... processes such as energy metabolism, cell growth and differentiation, maintenance of blood pressure and immune responses. Despite their importance and the fact that their impaired function has been associated with various diseases, there are only few studies on the potential disruption of glucocorti ...
... processes such as energy metabolism, cell growth and differentiation, maintenance of blood pressure and immune responses. Despite their importance and the fact that their impaired function has been associated with various diseases, there are only few studies on the potential disruption of glucocorti ...
Get PDF - Wiley Online Library
... two decades to identify neuropharmacologically active compounds [1]. Of specific interest are the peptide components of the venom. Each conus species is estimated to contain approximately 100–150 small (10–30 amino acids), highly structured, disulfide rich peptides, which are biosynthesized and secr ...
... two decades to identify neuropharmacologically active compounds [1]. Of specific interest are the peptide components of the venom. Each conus species is estimated to contain approximately 100–150 small (10–30 amino acids), highly structured, disulfide rich peptides, which are biosynthesized and secr ...
Functional characterization of LePGT1, a membrane
... of membrane-bound AS-PTs has been reported regardless of origin. In particular, no characterization of plant AS-PTs has been reported. This is mainly because of the difficulty in handling these proteins. Representative of membrane-bound AS-PTs are the PPT [PHB (p-hydroxybenzoic acid) prenyltransfera ...
... of membrane-bound AS-PTs has been reported regardless of origin. In particular, no characterization of plant AS-PTs has been reported. This is mainly because of the difficulty in handling these proteins. Representative of membrane-bound AS-PTs are the PPT [PHB (p-hydroxybenzoic acid) prenyltransfera ...
Essential amino acid
... production and maintenance of body proteins. Lysine: Deficiency can lead to poor appetite, reduction in body weight, anemia, and a reduced ability to concentrate, as well as pneumonia, kidney disease (nephritis), and acidosis, as well as with malnutrition and rickets in children. Methionine: Methion ...
... production and maintenance of body proteins. Lysine: Deficiency can lead to poor appetite, reduction in body weight, anemia, and a reduced ability to concentrate, as well as pneumonia, kidney disease (nephritis), and acidosis, as well as with malnutrition and rickets in children. Methionine: Methion ...
Sequences of the Nucleocapsid Genes from Two Strains of Avian
... for sequencing. For Beaudene the oligo(dT)-primed clone C5.322 was used, which includes the poly(A) tail derived from the 3' terminus of the viral genome and extends for 1930base pairs in the 5' direction. The production of this clone was exactly as described in Brown & Boursnell (1984). For M41 two ...
... for sequencing. For Beaudene the oligo(dT)-primed clone C5.322 was used, which includes the poly(A) tail derived from the 3' terminus of the viral genome and extends for 1930base pairs in the 5' direction. The production of this clone was exactly as described in Brown & Boursnell (1984). For M41 two ...
1dl5 Lichtarge lab 2006
... 2.4.2 Overlap with known functional surfaces at 25% coverage. The name of the ligand is composed of the source PDB identifier and the heteroatom name used in that file. SAH binding site. Table 2 lists the top 25% of residues at the interface with 1dl5SAH699 (sah). The following table (Table 3) sugge ...
... 2.4.2 Overlap with known functional surfaces at 25% coverage. The name of the ligand is composed of the source PDB identifier and the heteroatom name used in that file. SAH binding site. Table 2 lists the top 25% of residues at the interface with 1dl5SAH699 (sah). The following table (Table 3) sugge ...
chapt06b_lecture
... An example of enzyme induction is when E. coli is induced to use lactose as an energy source in the absence of glucose. The enzyme for lactose use is turned on by genetic control. In enzyme repression, the product of a biochemical pathway inhibits the functioning of a key enzyme of a previous step i ...
... An example of enzyme induction is when E. coli is induced to use lactose as an energy source in the absence of glucose. The enzyme for lactose use is turned on by genetic control. In enzyme repression, the product of a biochemical pathway inhibits the functioning of a key enzyme of a previous step i ...
The Energy Requirement for Growth: An A ~ ~ lication of
... mechanical work, maintenance of ionic equilibrium, and energy costs for replacing body constituents, as more becomes known about the stoichiometry of biochemical reactions in various organs. An important problem in human nutrition, especially in the rapidly growing individual, is to assess that part ...
... mechanical work, maintenance of ionic equilibrium, and energy costs for replacing body constituents, as more becomes known about the stoichiometry of biochemical reactions in various organs. An important problem in human nutrition, especially in the rapidly growing individual, is to assess that part ...
Supplementary Information
... Such a violation could be, for instance, that a reaction is used by an elementary flux mode ...
... Such a violation could be, for instance, that a reaction is used by an elementary flux mode ...
Structure-Function Analysis of the UDP-N-acetyl-D
... that retain the anomeric configuration of the sugar-nucleotide bond are thought to work via a double displacement mechanism, which would require two carboxylic acid side chains (12). Second, carboxylates could be involved in binding of substrate. Third, the activity of ppGaNTases requires the bindin ...
... that retain the anomeric configuration of the sugar-nucleotide bond are thought to work via a double displacement mechanism, which would require two carboxylic acid side chains (12). Second, carboxylates could be involved in binding of substrate. Third, the activity of ppGaNTases requires the bindin ...
Cell-Specific Localization of Glucose Transporter Proteins in
... in rat trachea. The antirat GST-Glut-2 antibody was species specific and failed to detect Glut-2 in human lung (data not shown). As the isoform specificity of all of the antifacilitative Glut antibodies used in this study has been extensively demonstrated previously by us and others using the corres ...
... in rat trachea. The antirat GST-Glut-2 antibody was species specific and failed to detect Glut-2 in human lung (data not shown). As the isoform specificity of all of the antifacilitative Glut antibodies used in this study has been extensively demonstrated previously by us and others using the corres ...
Click Here to download this tutorial as a PDF
... If you use hbonds off command, the hydrogen bonds in the currently selected area of the structure will be turned off. To remove just a single hydrogen bond, select only the two amino acids that the hydrogen bond connects and then use the hbonds off command. When Jmol calculates hydrogen bonds, it oc ...
... If you use hbonds off command, the hydrogen bonds in the currently selected area of the structure will be turned off. To remove just a single hydrogen bond, select only the two amino acids that the hydrogen bond connects and then use the hbonds off command. When Jmol calculates hydrogen bonds, it oc ...
AMINO ACIDS IN THE ASTEROIDAL WATER - USRA
... chondrites suggests that amino acids may be formed through Fischer-Tropsch type (FTT) gas-grain reactions after the meteorite parent body cooled to lower temperatures. β-alanine, which is a n-ω-amino acid [9], is also one of the most abundant amino acids in Zag, and its presence is consistent with i ...
... chondrites suggests that amino acids may be formed through Fischer-Tropsch type (FTT) gas-grain reactions after the meteorite parent body cooled to lower temperatures. β-alanine, which is a n-ω-amino acid [9], is also one of the most abundant amino acids in Zag, and its presence is consistent with i ...
PDF - Biochemical Journal
... A 3CI isotope-dilution method which provides an Institute of Animal Phy8iology, Babraham, Camadequate standard of reference for evaluation of bridge) other methods has been developed (Cotlove & The effects on glutamate dehydrogenase of Green, 1958). The present method involves comacetate (PMA) (Hell ...
... A 3CI isotope-dilution method which provides an Institute of Animal Phy8iology, Babraham, Camadequate standard of reference for evaluation of bridge) other methods has been developed (Cotlove & The effects on glutamate dehydrogenase of Green, 1958). The present method involves comacetate (PMA) (Hell ...
Essentiality and damage in metabolic networks
... connected compounds tend to be redundant since they are produced by many reactions. Surprisingly, some essential enzymes cause little damage and conversely, some non-essential enzymes cause serious damage. In the case of essential enzymes with low damage, we analyzed the bibliography provided by the ...
... connected compounds tend to be redundant since they are produced by many reactions. Surprisingly, some essential enzymes cause little damage and conversely, some non-essential enzymes cause serious damage. In the case of essential enzymes with low damage, we analyzed the bibliography provided by the ...
Metabolic Fate of Glucose Metabolic Fate of Fatty Acids
... synthesis rather than catabolism. • This is possible because the Km for aminoacyl tRNA synthetase is lower than that for catabolic enzymes. • AA catabolism takes place when the anobolic pathways are saturated. • Liver is the only organ capable of sequestering N as urea for disposal. • The α-keto aci ...
... synthesis rather than catabolism. • This is possible because the Km for aminoacyl tRNA synthetase is lower than that for catabolic enzymes. • AA catabolism takes place when the anobolic pathways are saturated. • Liver is the only organ capable of sequestering N as urea for disposal. • The α-keto aci ...
Chromatography (Principles and Classifications)
... mixture of as many 10,000 proteins, each of which are made up of the same constituent amino acids. Proteins differ in size (how many amino acids), charge (how many positively and negatively charged amino acids), and in sequence and presence of specific binding sites on the proteins. Any techniqu ...
... mixture of as many 10,000 proteins, each of which are made up of the same constituent amino acids. Proteins differ in size (how many amino acids), charge (how many positively and negatively charged amino acids), and in sequence and presence of specific binding sites on the proteins. Any techniqu ...
Nucleotide sequence of a cytomegalovirus single
... region is a direct repeat of the 7 nt sequence GGACAGT at positions - 112 to - 106 and -203 to - 197. The deduced DB129 amino acid sequence shares about 72% identity with its HCMV counterpart UL57 and the similarity is roughly collinear from the amino to the carboxyl terminus (M. Chee, personal comm ...
... region is a direct repeat of the 7 nt sequence GGACAGT at positions - 112 to - 106 and -203 to - 197. The deduced DB129 amino acid sequence shares about 72% identity with its HCMV counterpart UL57 and the similarity is roughly collinear from the amino to the carboxyl terminus (M. Chee, personal comm ...
The Bacterial Phosphotransferase System: Structure, Function
... donor for sugar phosphorylation and the presence of three essential catalytic entities, termed Enzyme I, Enzyme II and HPr (heat-stable, histidine-phosphorylatable protein). The discovery of this system provided an explanation for pleiotropic carbohydrate-negative mutants of E. coli described as ear ...
... donor for sugar phosphorylation and the presence of three essential catalytic entities, termed Enzyme I, Enzyme II and HPr (heat-stable, histidine-phosphorylatable protein). The discovery of this system provided an explanation for pleiotropic carbohydrate-negative mutants of E. coli described as ear ...
Enzymes and pH Review Game with Answers 2013 2014
... interfere with the cell's abilities to catalyze various reactions. C) Elevated body temperatures will increase the energy of activation needed to start various chemical reactions in the body. This will interfere with the ability of enzymes to catalyze vital chemical reactions. D) Elevated body tempe ...
... interfere with the cell's abilities to catalyze various reactions. C) Elevated body temperatures will increase the energy of activation needed to start various chemical reactions in the body. This will interfere with the ability of enzymes to catalyze vital chemical reactions. D) Elevated body tempe ...
Enantioselective -Hydroxylation of 2-Arylacetic Acid Derivatives and r
... hydroxylates long-chain fatty acids at the ω-1, ω-2, and ω-3 positions at high rates.9 BM-3 has provided an evolvable protein framework for obtaining modified or new activities. Rational design and directed evolution approaches have created BM-3 variants with activity on medium-chain fatty acids,10 ...
... hydroxylates long-chain fatty acids at the ω-1, ω-2, and ω-3 positions at high rates.9 BM-3 has provided an evolvable protein framework for obtaining modified or new activities. Rational design and directed evolution approaches have created BM-3 variants with activity on medium-chain fatty acids,10 ...
Safety Assessment of Soy Proteins and Peptides as Used in
... The definitions and functions of the soy peptide ingredients included in this report are provided in Table 1. The soy protein and peptide derivatives form a broad category of materials which are prepared by extraction from soy and partial hydrolysis to yield cosmetic ingredients. Protein hydrolysate ...
... The definitions and functions of the soy peptide ingredients included in this report are provided in Table 1. The soy protein and peptide derivatives form a broad category of materials which are prepared by extraction from soy and partial hydrolysis to yield cosmetic ingredients. Protein hydrolysate ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.