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Metabolic signals in sleep regulation: recent insights The Harvard
Metabolic signals in sleep regulation: recent insights The Harvard

... the internal circadian clock in response to the external environmental cues establishes rhythmicity of the physiological processes and hormonal release. These alterations are associated with the sleep-wake-state changes3,4 and the feeding-fasting cycles.5 Together, they maintain the energy balance t ...
The contribution of sleep to hippocampus
The contribution of sleep to hippocampus

... ories, including procedural memory (e.g. mirror tracing) and the amygdala-dependent enhancement of emotional declarative memories, benefited particularly from periods of REM sleep-rich late sleep. But deviations from this dichotomy indicate that more features need consideration: for instance, in one ...
Rapid eye movement sleep deprivation induces an increase in
Rapid eye movement sleep deprivation induces an increase in

... increased availability of noradrenaline as evidenced by an increase in whole brain noradrenaline turnover (28), an increase in tyrosine hydroxylase mRNA and enzyme activity (29-31), a decrease in the activity of monoaminoxidase A (32,33), a downregulation of beta-adrenergic receptors (34), and a dec ...
Issues in Pain Management
Issues in Pain Management

... • 80% of Americans experience LBP at some point during their lifetime. • Annual prevalence of LBP about 30% • Most common cause of disability under age 45 • Accounts for 12.5% of all sick days (Frank, 1993) • Second most common reason for visits to MD (Hart, ...
D27 - Viktor`s Notes for the Neurosurgery Resident
D27 - Viktor`s Notes for the Neurosurgery Resident

... N.B. melatonin secretion is not dependent upon sleep, persisting in individuals kept awake at night.  melatonin has phase-shifting properties opposite to bright light effects: melatonin administered in afternoon produces phase advances, whereas melatonin given in morning produces phase delays. ...
Sleep Health and Appropriate Use of OTC Sleep
Sleep Health and Appropriate Use of OTC Sleep

... for infants to about 7–8 in old age). Even within age groups, there is variability in need for sleep. Overall, Americans get less sleep than they need. Data from polls conducted by the National Sleep Foundation (NSF) show that Americans sleep an average of 6 hr and 31 min each night, about an hour l ...
The Current Prevalence of Sleep Disordered Breathing in
The Current Prevalence of Sleep Disordered Breathing in

... and CSR, an association between NYHA functional class and CSR has not been previously reported to our knowledge. Although this finding would support the notion that CSR is a consequence of progressive heart failure, and in fact patients in our cohort with CSR had significantly lower LVEFs than those ...
Committee on Accreditation for Respiratory Care
Committee on Accreditation for Respiratory Care

...  Graduates are eligible to take the Registered Polysomnographic Technologist Exam (RPSGT) administered by the Board of Registered Polysomnographic Technologists (BRPT) without additional on-the-job training (Pathway #3). Other credentialed RTs must complete 6 months FT OJT experience to become elig ...
University of Groningen The relation between sleep and violent
University of Groningen The relation between sleep and violent

... If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons ...
Study Session 16 Mental Health Problems in Daily Life
Study Session 16 Mental Health Problems in Daily Life

... Common causes of sleeping problems include: bad sleeping habits, undetected mental illness (depression, anxiety, psychosis), social problems (e.g. somebody has died, not enough food for the family), stimulants or other drugs (coffee, alcohol, khat, prescribed medications), a physical health problem ...
Sleep Spindles as Facilitators of Memory Formation and Learning
Sleep Spindles as Facilitators of Memory Formation and Learning

... immediately after training [22]. In the same species, spindles particularly at the transition to REM sleep were shown to be involved in the consolidation of novel memories [23]. These studies show that spindles play a role in learning also in other species and that laboratory animals can be used to ...
Insomnia
Insomnia

... Coexistence vs. being secondary to. When coexisting condition adequately treated, insomnia often persists.  Medical conditions: 10% of pts with insomnia have chronic condition or take Rx. Conversely, 40% of pts with medical problems have insomnia. ...
Cognitive screening Instruments
Cognitive screening Instruments

...  Sudden ...
Performance vigilance task and sleepiness in patients with sleep- disordered breathing
Performance vigilance task and sleepiness in patients with sleep- disordered breathing

... the diurnal impairment in these patients? These two questions are of substantial relevance in the estimation of the actual daytime effects of the disorder [17] and, consequently, efficacy of therapy. The present study analysed subjective and objective alertness, as well as performance, in a large sa ...
Normal sleep and circadian rhythms: Neurobiologic mechanisms
Normal sleep and circadian rhythms: Neurobiologic mechanisms

... during waking hours. The pull of this drive builds up during wakefulness and reaches its peak at sleep time. Its strength declines during sleep with the lowest point (nadir) on awakening in the morning. It also is useful to differentiate sleepiness from tiredness or fatigue. A tired or fatigued indi ...
Cerebral correlates of delta waves during non
Cerebral correlates of delta waves during non

... values of delta power is likely to obscure the interpretation of the results. Therefore, in our second analysis, data obtained during wakefulness were discarded from the statistical analysis. As shown in Fig. 1, this analysis run on data exclusively recorded during NREM sleep yielded markedly differ ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... significant hypoventilation during sleep, characterized by episodes of partial or complete upper airway obstruction associated with hypoxemia and/or hypercarbia”(2). OSAS is characterised by sleep disturbances resulting in behavioural problems, poor school performance, failure to thrive (2),daytime ...
notes 2 of 4
notes 2 of 4

... •the study is the first-of-its-kind to show an association between insufficient sleep and biologically more aggressive tumors as well as likelihood of cancer recurrence ...
Yale Review of Undergraduate Research in
Yale Review of Undergraduate Research in

... but the mPFC is more active over the long term. Howev- also investigated by comparing ripple activity in day 6 to er, this is opposite in the sleep-deprived group. mean errors in day 7. The rationale was that if ripple acA possible explanation here is that the hippocam- tivity was correlated with me ...
Parasomnias and nocturnal frontal lobe epilepsy
Parasomnias and nocturnal frontal lobe epilepsy

... drug withdrawal (in particular, alcohol and benzodiazepines). The chronic form is more common in the elderly and in males. Practitioners should have a high index of suspicion for this diagnosis when an elderly patient presents for the first time with a parasomnia. Chronic RBD can be either idiopathi ...
Natural course of sleep-disordered breathing after acute myocardial infarction
Natural course of sleep-disordered breathing after acute myocardial infarction

... The prevalence of moderate-to-severe sleep apnoea (apnoea/ hypopnoea index (AHI) o15 events?h-1) in the entire sample of AMI patients was 55% at ,5 days after PCI, of whom half predominantly had CSA and half predominantly had OSA, respectively. After the 12-week observational period, there was a mod ...
Misdiagnosing sleep disorders as primary psychiatric conditions
Misdiagnosing sleep disorders as primary psychiatric conditions

... because of the large numbers of people involved. This is partly due to increases in 24-hour consumer services, although occupations such as nursing and police work may inevitably involve shift work. Many (possibly most) shift workers suffer psychological problems as well as physical complaints as a ...
Hypoglossal nerve stimulation for sleep apnoea
Hypoglossal nerve stimulation for sleep apnoea

... for UPPP (item number 41486) have remained constant over the past five years, with approximately 1200 claims per year.15 Long-term follow-up studies have suggested that the initial effect of surgery may lessen over time.16 Due to the limited effectiveness of treatment alternatives, Eastwood et al (2 ...
Physiological Mechanisms of Sleep and Waking
Physiological Mechanisms of Sleep and Waking

... Physiological Mechanism of Sleep and Waking Neural Control of Arousal Circuits of neurons that secrete at least five different neurotransmitters play a role in some aspect of an animal’s level of alertness and wakefulness—what is commonly called arousal: acetylcholine, norepinephrine, serotonin, hi ...
Control of Wake and Sleep States
Control of Wake and Sleep States

... Sleep induction is mediated by homeostatic factors adenosine and nitric oxide in BF and neocortex and by increased activity of median pro-optic nucleus GABA neurons that inhibit the wake-promoting neurons of ARAS. Circadian influences are mediated by direct retinal and indirect SCN projections to GA ...
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Start School Later movement

The Start School Later movement refers to a series of efforts in the U.S.A. by health care professionals, sleep scientists, educators, economists, legislators, parents, students, and other concerned citizens to restore a later start to the school day, based on a growing body of evidence that starting middle and high schools too early in the morning is unhealthy, counterproductive, and incompatible with adolescent sleep needs and patterns. During the second half of the 20th century, many public schools in the United States began shifting instructional time earlier than the more conventional bell time, thought to be about 9 a.m. Today it is common for American schools to begin the instructional day in the 7 or 8 a.m. hour and end about seven hours later, around 2 p.m. Most sleep research suggests that morning classes should begin no earlier than 8:30 a.m. for middle and high school students.Advocates of a return to later school start times argue that sleep and school hours should be viewed as a public health issue, citing evidence linking early school start times to widespread sleep deprivation among teenagers as well as a wide array of acute and chronic physical, psychological, and educational problems. Not only do students consistently get significantly more sleep on school nights when their schools move to later start times, but later school hours have been consistently linked with improved school performance, reduced impulsiveness, and greater motivation, as well as with lower rates of depression, tardiness, truancy, and morning automobile accidents. Recent studies suggest that early school start times disproportionately hurt economically disadvantaged students and may even negatively impact future earning potential of students, offsetting any financial savings to the school system attributed to earlier hours.
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