medical chemistry and biochemistry
... 3. Identify the major recognized types of secondary structure and explain supersecondary motifs. 4. Describe the kind and relative strength of the forces that stabilize each order of protein structure and indicate the present state of knowledge concerning the stepwise process by which protein are th ...
... 3. Identify the major recognized types of secondary structure and explain supersecondary motifs. 4. Describe the kind and relative strength of the forces that stabilize each order of protein structure and indicate the present state of knowledge concerning the stepwise process by which protein are th ...
Facing extremes: archaeal surface-layer (glyco)proteins
... glycosylation, suggesting that motifs apart from the consensus Asn-Xaa-Ser/Thr sequence are recognized by the haloarchaeal glycosylation machinery (Zeitler et al., 1998). Finally, several studies addressing S-layer glycoprotein glycosylation suggest that in archaea, protein glycosylation occurs on t ...
... glycosylation, suggesting that motifs apart from the consensus Asn-Xaa-Ser/Thr sequence are recognized by the haloarchaeal glycosylation machinery (Zeitler et al., 1998). Finally, several studies addressing S-layer glycoprotein glycosylation suggest that in archaea, protein glycosylation occurs on t ...
Chromatin Condensing Functions of the Linker Histone C
... that intrinsically disordered domains contain short primary sequence elements imbedded within the domain (24-26). In addition, interesting attributes related to amino acid composition have been observed, such as reduced levels of hydrophobic residues and increased levels of charged residues (21, 27) ...
... that intrinsically disordered domains contain short primary sequence elements imbedded within the domain (24-26). In addition, interesting attributes related to amino acid composition have been observed, such as reduced levels of hydrophobic residues and increased levels of charged residues (21, 27) ...
Phosphorylation of apoproteins in VLDL, and LDL by protein
... for apo BlOO phosphorylated by CAMP-PKcompared with AMPPK (Figure lb). This indicates that these two kinases phosphorylate different sites. This has also been suggested by reversed phase HPLC separation of tryptic peptides from apo BlOO phosphorylated by either kinase and will be confmed when these ...
... for apo BlOO phosphorylated by CAMP-PKcompared with AMPPK (Figure lb). This indicates that these two kinases phosphorylate different sites. This has also been suggested by reversed phase HPLC separation of tryptic peptides from apo BlOO phosphorylated by either kinase and will be confmed when these ...
Journal of Biological Chemistry
... upon amino acid incorporation into protein of the liver ribosome system (Table II) just as effectively as it does the decrease in hepatic ATP concentration induced by the same analogue (3). These results tend to implicate cellular BTP deficiency as being important in the inhibition of protein synthe ...
... upon amino acid incorporation into protein of the liver ribosome system (Table II) just as effectively as it does the decrease in hepatic ATP concentration induced by the same analogue (3). These results tend to implicate cellular BTP deficiency as being important in the inhibition of protein synthe ...
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... o r i e n t a t i o n of t e r m i n a l bases during codon recognition. 5 ' - T e r m i n a l a n d perhaps also 3 ' - t e r m i n a l codons possibly serve, t o g e t h e r with neighboring codons, as operator regions. Since m a n y enzymes h a v e been described which catalyze the transfer of nuc ...
... o r i e n t a t i o n of t e r m i n a l bases during codon recognition. 5 ' - T e r m i n a l a n d perhaps also 3 ' - t e r m i n a l codons possibly serve, t o g e t h e r with neighboring codons, as operator regions. Since m a n y enzymes h a v e been described which catalyze the transfer of nuc ...
Allosteric pathways in imidazole glycerol phosphate synthase
... and/or thermodynamic parameters of the biochemical reaction in the active site. Allosteric information transfer can range from large, enthalpically driven conformational changes to purely entropically driven motions or a combination of both enthalpic and entropic effects, but in each case the kineti ...
... and/or thermodynamic parameters of the biochemical reaction in the active site. Allosteric information transfer can range from large, enthalpically driven conformational changes to purely entropically driven motions or a combination of both enthalpic and entropic effects, but in each case the kineti ...
Relationships Analyzing Amino-Acid Sequences to Determine
... 2. In the study of hemoglobin, which vertebrate is most closely related to humans? Least closely related? 3. Why can it be said that proteins behave like molecular clocks? 4. When the portions of the gorilla and human hemoglobin molecules were compared, there was only one difference in the amino-aci ...
... 2. In the study of hemoglobin, which vertebrate is most closely related to humans? Least closely related? 3. Why can it be said that proteins behave like molecular clocks? 4. When the portions of the gorilla and human hemoglobin molecules were compared, there was only one difference in the amino-aci ...
126 EFFECT OF ULTRAVIOLET-B IRRADIATION ON FATTY ACIDS
... estimated before and after exposure to UV-B radiation using SPSS version 10.0. Differences were considered significant at P 0.05. The effect of UV-B radiation on these parameters was considered to be statistically significant at a level of P ...
... estimated before and after exposure to UV-B radiation using SPSS version 10.0. Differences were considered significant at P 0.05. The effect of UV-B radiation on these parameters was considered to be statistically significant at a level of P ...
Solubility of recombinant Src homology 2 domains expressed in E
... βC strand of the human TSAd SH2 domain (Figure 1) harbours a nine aa sequence (SAVTFVLTY) with near 100% propensity for intermolecular beta-sheet aggregation (Figure 3A). Similar results were obtained for the murine and rat sequences, whereas no beta-aggregating regions were found in the Lck-SH2 dom ...
... βC strand of the human TSAd SH2 domain (Figure 1) harbours a nine aa sequence (SAVTFVLTY) with near 100% propensity for intermolecular beta-sheet aggregation (Figure 3A). Similar results were obtained for the murine and rat sequences, whereas no beta-aggregating regions were found in the Lck-SH2 dom ...
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... topologicalforms ofprionprotein in the endoplasmic reticulum membrane and theirrole inthe pathophysiologicalprocess of the disease. But still prion diseases continue 1o raise many unanswerable questions to be investigated. One of the unanswerable questions is prion muhiplication. Many prion multipli ...
... topologicalforms ofprionprotein in the endoplasmic reticulum membrane and theirrole inthe pathophysiologicalprocess of the disease. But still prion diseases continue 1o raise many unanswerable questions to be investigated. One of the unanswerable questions is prion muhiplication. Many prion multipli ...
Pathways of genetic code evolution in ancient and modern organisms
... reassigning codon(s) from older to newer amino acids. In the modern phase, reassignment occurs only among the same set of 20 amino acids, and code evolution is not characterized by an increase in the repertoire of encoded amino acids. This suggests that selection also creates barriers to change and ...
... reassigning codon(s) from older to newer amino acids. In the modern phase, reassignment occurs only among the same set of 20 amino acids, and code evolution is not characterized by an increase in the repertoire of encoded amino acids. This suggests that selection also creates barriers to change and ...
Studier`s autoinduction media
... fresh overnight culture grown in PA-0.5G. Growth at 37C from a thousand-fold dilution into PASM5052 typically reaches saturation in 14-16 hours. Growth at 20C is much slower and a culture can take 3 days or longer to become induced and reach saturation. Although still testing, we expect that the c ...
... fresh overnight culture grown in PA-0.5G. Growth at 37C from a thousand-fold dilution into PASM5052 typically reaches saturation in 14-16 hours. Growth at 20C is much slower and a culture can take 3 days or longer to become induced and reach saturation. Although still testing, we expect that the c ...
The Interaction between Dietary Protein and Bone Health
... 50-89 with previous hip fractures and matched them with controls of the same age and sex in a case-control study. The 2501 subjects’ diets were assessed using a picturesort food frequency questionnaire. Protein intake was stratified into quartiles and logistic regression was applied controlling for ...
... 50-89 with previous hip fractures and matched them with controls of the same age and sex in a case-control study. The 2501 subjects’ diets were assessed using a picturesort food frequency questionnaire. Protein intake was stratified into quartiles and logistic regression was applied controlling for ...
Soy Protein Based Green Composite: A Review
... between protein chains typically leads to brittle films therefore it is difficult to process [18]. Plasticizers is use to break intermolecular linkage and therefore stabilizes protein in their primitive structure and makes the protein chains mobile [19]. Hence, addition of a plasticizer is generally ...
... between protein chains typically leads to brittle films therefore it is difficult to process [18]. Plasticizers is use to break intermolecular linkage and therefore stabilizes protein in their primitive structure and makes the protein chains mobile [19]. Hence, addition of a plasticizer is generally ...
Green Fluorescent Protein
... Youvan, Douglas., Gregory Flynn. "Chromophore formation in Green Fluorescent Protein" (1997) Biochemistry vol. 36 6786-6791 ...
... Youvan, Douglas., Gregory Flynn. "Chromophore formation in Green Fluorescent Protein" (1997) Biochemistry vol. 36 6786-6791 ...
Engineering carbonic anhydrase for highly selective ester hydrolysis Gunnar Höst
... amino acids. Usually, some stretches of amino acids in the primary structure tend to form local stable structures through hydrogen bonding interactions between groups in the peptide backbone. This is called the secondary structure, and contains elements such as α-helices and β-sheets. The tertiary s ...
... amino acids. Usually, some stretches of amino acids in the primary structure tend to form local stable structures through hydrogen bonding interactions between groups in the peptide backbone. This is called the secondary structure, and contains elements such as α-helices and β-sheets. The tertiary s ...
Protein expression by a Beijing strain differs from that of another
... was mainly growth phase dependent, although some differences between the strains were observed. However, due to the low resolving power of 1D gel electrophoresis, the identity of the differentially expressed proteins could not be ascertained. Here, we have extended our previous study through the use ...
... was mainly growth phase dependent, although some differences between the strains were observed. However, due to the low resolving power of 1D gel electrophoresis, the identity of the differentially expressed proteins could not be ascertained. Here, we have extended our previous study through the use ...
Distribution and phylogeny of the bacterial translational GTPases
... factors that utilize GTP are called translational GTPases (trGTPases). Four large families of trGTPases - IF2/eIF5B, SelB/eIF2γ, EF-Tu/EF-1α and EFG/EF-2 - can be distinguished (Leipe et al. 2002). For each of those families one ancestral gene existed in the last universal common ancestor (LUCA) (Le ...
... factors that utilize GTP are called translational GTPases (trGTPases). Four large families of trGTPases - IF2/eIF5B, SelB/eIF2γ, EF-Tu/EF-1α and EFG/EF-2 - can be distinguished (Leipe et al. 2002). For each of those families one ancestral gene existed in the last universal common ancestor (LUCA) (Le ...
Cambridge Isotope Laboratories, Inc. RefeRences 1. Shadforth, I.P.
... the mass spectrometer from liquid chromatography columns. In the mass spectrometer they are easily distinguished by their mass. Algorithms are then used to extract the light and heavy peptide ion chromatograms, which represent the peptide’s abundance. The light / heavy ratios are used to infer relat ...
... the mass spectrometer from liquid chromatography columns. In the mass spectrometer they are easily distinguished by their mass. Algorithms are then used to extract the light and heavy peptide ion chromatograms, which represent the peptide’s abundance. The light / heavy ratios are used to infer relat ...
Protein structure prediction
Protein structure prediction is the prediction of the three-dimensional structure of a protein from its amino acid sequence — that is, the prediction of its folding and its secondary, tertiary, and quaternary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry; it is highly important in medicine (for example, in drug design) and biotechnology (for example, in the design of novel enzymes). Every two years, the performance of current methods is assessed in the CASP experiment (Critical Assessment of Techniques for Protein Structure Prediction). A continuous evaluation of protein structure prediction web servers is performed by the community project CAMEO3D.