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Translation PPT
Translation PPT

... How can you code for 20 amino acids with only 4 nucleotide bases (A,U,G,C)? ...
13.3: RNA and Gene Expression
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... • Translation occurs in a sequence of steps, involves three kinds of RNA, and results in a complete polypeptide. • Translation takes place in the cytoplasm, where tRNA, rRNA, and mRNA interact to assemble proteins. • A specific amino acid is added to one end of each tRNA. The other end of the tRNA h ...
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... The Genetic Code DNA is the hereditary material responsible for all the characteristics of an organism and it controls all the activities of a cell. It is able to do this as it carries information, which controls the synthesis of proteins. An important class of proteins is enzymes that control all ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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