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Absorption and Fluorescence Properties of Some Basic
Absorption and Fluorescence Properties of Some Basic

... tration change of extinction coefficient8. Therefore, at the concentration (8 10~6M ) of acridine orange employed here, the concentrations of monomer and dimer are estimated to be 6.4 -10-6 and 8 10~7M, respectively. For this reason, the enhancement of fluorescence observed can not be attributable t ...
Siena Borsani - Unisi.it - Università degli Studi di Siena
Siena Borsani - Unisi.it - Università degli Studi di Siena

... and medical records of 100,000 volunteers, in order to enable research into personalized medicine. It was initiated by Harvard University's George Church and announced in January 2006 Data will be freely available over the Internet, so that researchers can test various hypotheses about the relations ...
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... They often take place in different locations in the cells (compartmentalization β-oxidation-mutochondria syn of fatty acids – cytosol. Cellular regulation of metabolic pathways Metabolic pathways can be linear, e.g. glycolysis or can be cyclic, e.g. TCA. In general, the rate of catabolism is control ...
Polymerase chain reaction
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... and shows some of the results from his experiments with PCR. Only Joshua Lederberg, a Cetus consultant, shows any interest. Later at the meeting, Mullis is involved in a physical altercation with another Cetus researcher, over a dispute unrelated to PCR. The other scientist soon leaves the company, ...
Applied Biology Final Exam Review Sheet Exam: Friday (June 21st
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... correct amino acid sequence (using the codon table of amino acids) – Practice: If the DNA strand reads: TAC TTG GCG AGC ATT TAC GAA what is the (1) mRNA code and the (2) amino acid sequence (use pg. 303 Table 12.17 or the table on the worksheet you were given in class) 8) Assume that the DNA sequenc ...
Expanding the Genetic Code of Escherichia coli
Expanding the Genetic Code of Escherichia coli

... should be generalizable to other amino acids with novel spectroscopic, chemical, or structural properties. Indeed, we have shown that the E. coli ribosome is able to incorporate amino acids with a wide array of side chains into proteins using in vitro protein synthesis (2). Additional orthogonal tRN ...
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AKUBOH OLIVIA 13/SCI03/001 BCH 413 METALLOENZYMES
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Nitrosation of aspartic acid, aspartame, and glycine ethylester
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... the effect of the side chain on the preceding steps is not known. In this report, the nitrosation of amino acids and derivatives, including the artificial sweetener aspartame, is investigated in vitro in order to determine the rate of nitrosation. The alkylating activity is studied with a model nucl ...
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A Conserved Family of Nuclear Proteins Containing

... by several maternally active genes (see above), by Kr, a blastoderm gastrulation-specific segmentation gene, and by the Kr h gene, which extends its action into later embryonic stages, encouraged studies with the anti-H/C link antibodies on polytene salivary gland chromosomes. If the antigen were pr ...
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... 1. In translation, the cell uses an mRNA strand as a template to assemble proteins. The cell has just transcribed this mRNA strand from its DNA, and it now translates the mRNA’s nucleotide sequence into a chain of amino acids. This chain, called a polypeptide, forms the basic structure of a protein. ...
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... the .{3} specifies the intervening codon. To allow some but not all amino acids to occupy this “lysine rich region” we would have to write the regex for each one allowed and separate them with the OR symbol | called “pipe”. (11d) Why might a researcher be interested in looking for secondary structur ...
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... 80 V), the gel is viewed under long wave UV light and a slit cut in the gel, just ahead of the desired band. A piece of DEAE paper is inserted in the slit. Another piece of DEAE paper can be inserted behind the desired band, to prevent unwanted bands being trapped by the paper. Electrophoresis is co ...
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Comments received
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... mutations, as with X-rays. All such earlier procedures worked within single or closely related species. The nub of the new technology is to move genes back and forth, not only across species lines, but across any boundaries that now divide living organisms. The results will be essentially new organi ...
Literature 07/19/2010
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... benzamide)−poly(ethylene glycol) (OPBA−PEG) copolymers using solid‐state NMR supported by wide‐ angle  X‐ray  scattering  (WAXS),  differential  scanning  calorimetry  (DSC),  and  polarization  optical  microscopy  (POM).  It  was  found  that  longer  OPBAs  form  layered  β‐sheet‐like  aggregates ...
the genetics of viruses and bacteria
the genetics of viruses and bacteria

... Antibiotics, which can kill bacteria by inhibiting enzymes or processes specific to bacteria, are powerless against viruses, which have few or no enzymes of their own. ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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