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COMPARATIVE EVALUATION OF POTATO STARCH AND BANANA POWDER AS
COMPARATIVE EVALUATION OF POTATO STARCH AND BANANA POWDER AS

... Objective: The main objective of this research was to introduce and evaluate disintegrant property of natural excipients like potato starch and banana powder in tablet formulation. Pharmaceutical excipients developed from natural sources are economic. Methods: Dehydrated banana powder and potato sta ...
Additive anticancer effects of chrysin and low dose cisplatin
Additive anticancer effects of chrysin and low dose cisplatin

... Additive apoptotic effect of chrysin and low-dose cisplatin combination in human glioma cells (U87) The effect of the combination treatment on apoptosis induction in these cells was further demonstrated by Annexin V/PI staining. Human glioma cells (U87) were treated with 40 µM chrysin, 2.0 µM cispla ...
"פורמט עלון זה נקבע ע"י משרד הבריאות ותוכנו נבדק ואושר"
"פורמט עלון זה נקבע ע"י משרד הבריאות ותוכנו נבדק ואושר"

... Hepatic toxicity: Chronic hepatitis, as evidenced by elevations of hepatic enzymes and bilirubin have been reported during use of papaverine. Most of the affected patients were also consuming alcohol and a causal relationship to papaverine has not been proven. Routine monitoring of hepatic function ...
Triumeq - ViiV Healthcare
Triumeq - ViiV Healthcare

... HLA-B*5701-negative patients may develop a hypersensitivity reaction to abacavir; however, this occurs significantly less frequently than in HLA-B*5701-positive patients. Regardless of HLA-B*5701 status, permanently discontinue TRIUMEQ if hypersensitivity cannot be ruled out, even when other diagnos ...
10.1 Case Report Forms
10.1 Case Report Forms

... guidelines for the management of the pain exist and it is a topic of great discussion. The area is further complicated by the fact that only a few clinical trials have been carried out (WilderSmith et al. 1999 [1]). The best attempt to establish clear guidelines for the treatment of chronic pancreat ...
Absorbed Dose
Absorbed Dose

... Was it possible that the dose of yohimbine administered was too low to have produced a positive effect on male sexual function? Apparently not. Larger doses of Yohimbine were given in another study involving eighty-two impotent men. With higher doses 14 percent reported a full return of sexual funct ...
Medicines Information Bulletin - Oxford Health NHS Foundation
Medicines Information Bulletin - Oxford Health NHS Foundation

... according to response, usual dose 1-2g daily. Therefore, based on this recommendation, the dose equivalence, and tablet strengths, we suggest the following dosing guidelines ...
here - Plenge Gen @rplenge
here - Plenge Gen @rplenge

... to start drug discovery “Drug” “Target” ...
Guidelines for the prescribing and administration of `when required
Guidelines for the prescribing and administration of `when required

... Clearly state the route, frequency, maximum dose and indication for PRN medication. If it is clinically appropriate for the dose to be prescribed as a range, the lowest strength should be offered first. The maximum single dose of IM haloperidol permitted within AWP is 5mg. ‘PRN’ procyclidine should ...
Benzodiazepines
Benzodiazepines

... • Short-acting night sedation can lead to daytime use (i.e. when taken to avoid withdrawal) • Similarly, continuance of use avoids withdrawal • Long-term use is common and associated with: – excessive sedation – cognitive impairment – increased risk of accidents – adverse sleep effects – dependence ...
- Journal of Allergy and Clinical Immunology
- Journal of Allergy and Clinical Immunology

... cannot be classified because of our lack of mechanistic information. Theoretically, any drug can induce an immune response. However, some drugs are more likely to elicit clinically relevant immune responses than are others. Drugs in this category include antimicrobial drugs, anticonvulsants, chemoth ...
CRIXIVAN - cri.or.th
CRIXIVAN - cri.or.th

... conducted a lot of research about this virus and they have studied the life cycle of virus. Can produce based on these studies they have produced many chemicals that interfere with three major pathway of viral life cycle; reverse transcriptase inhibitors; integrase inhibitors; and is protease inhibi ...
Gastrointestinal formulary - Wirral Medicines Management
Gastrointestinal formulary - Wirral Medicines Management

... According to NICE guidance, infliximab should only be used in: • Patients with severe, active Crohn’s disease. • Patients whose condition has not responded to a full course of corticosteroids or an immunosuppressant or in those patients contraindicated to such therapies. • Patients for whom surgery ...
Quantitative Prediction of Transporter- and Enzyme
Quantitative Prediction of Transporter- and Enzyme

... many clinically important anionic drugs, including 3-hydroxy3-methylglutaryl coenzyme A reductase inhibitors (statins) (Shitara and Sugiyama, 2006; Kalliokoski and Niemi, 2009; All authors are full-time employees of Pfizer. The authors have no conflicts of interest that are directly relevant to this ...
Future Therapies for chronic noninfectious Uveitis
Future Therapies for chronic noninfectious Uveitis

... Peptide B27PD is an HLA class I antigen that mimics ocular S-antigen, thereby directing an immune response toward these antigens in the eye.29 In a small pilot trial in 9 chronic autoimmune uveitis patients who were treated with peptide B27PD, 4 mg tid for 12 weeks and followed for 5 years, treatmen ...
formulation and in vitro evaluation of microspheres of metoprolol
formulation and in vitro evaluation of microspheres of metoprolol

... means high blood pressure with no obvious medical cause. The remaining 5–10% of cases (Secondary hypertension) is caused by other conditions that affect the kidneys, arteries, heart or endocrine system. Persistent hypertension is one of the risk factors for stroke, myocardial infarction, heart failu ...
Comparison of Tibial Intraosseous, Sternal Intraosseous
Comparison of Tibial Intraosseous, Sternal Intraosseous

... The Advanced Cardiac Life Support (ACLS) recommendation for the endotracheal administration of epinephrine is 2 to 2.5 times the IV dose. The Pediatric Advanced Life Support (PALS) recommendation for endotracheal epinephrine is 10 times the IV dose. Whereas no studies were used to establish these do ...
PRODUCT MONOGRAPH BeneFIX® Coagulation Factor IX
PRODUCT MONOGRAPH BeneFIX® Coagulation Factor IX

... BeneFIX has no or negligible influence on the ability to drive or use machines. ADVERSE REACTIONS Adverse Drug Reaction Overview As with the intravenous administration of any protein product, the following reactions may be observed after administration: headache, fever, chills, flushing, nausea, vom ...
Gout
Gout

... long been used, although it has only recently (in 2009) been approved by the Food and Drug Administration (FDA) for use in patients with acute gout. In a randomized trial, colchicine (at a dose of 1.2 mg at the onset of a flare, followed by 0.6 mg 1 hour later) was significantly more likely than pla ...
Numbers-needed-to-treat analysis: an explanation using
Numbers-needed-to-treat analysis: an explanation using

... Trials of antipsychotics Much of the available clinical information on anti­psychotic treatment comes from companysponsored efficacy trials carried out for registration purposes. Since the publication of the NICE appraisal of the use of atypical antipsychotics (National Institute for Clinical Excell ...
An open-label, randomized, crossover study to assess anti-inflammatory effect
An open-label, randomized, crossover study to assess anti-inflammatory effect

... Many cytokines are activated in the synovium by various cell populations, several of them secreted by macrophage-like cells (Zwerina et al, 2005). They include TNF and interleukin 1, which constitute the therapeutic targets of several compounds for rheumatoid arthritis that directly inhibit these in ...
Characterization of a gastrointestinal tract microscale cell culture
Characterization of a gastrointestinal tract microscale cell culture

... soluble proteins and metabolites) in humans or animals not easily studied in vivo or in silico and to apply these observations to toxicology studies. A three-chamber (lung, liver, and other tissues) microscale cell culture analog (mCCA) was previously developed using tools from the semiconductor ind ...
Seizure Management in Dogs and Cats
Seizure Management in Dogs and Cats

... idiopathic) is the term used if an underlying cause cannot be identified. If seizures result from a structural lesion, they are defined as secondary epileptic seizures. Epilepsies are also described as asymptomatic (i.e., primary, idiopathic) and symptomatic (i.e., secondary). Symptomatic seizures a ...
PLAN B PRODUCT MONOGRAPH
PLAN B PRODUCT MONOGRAPH

... There are in general no serious adverse drug reactions to report following the use of Plan B®, either in clinical trials or post-market surveillance. Most commonly observed adverse drug reactions are presented in the following sections. Clinical Trial Adverse Drug Reactions Because clinical trials a ...
Intravitreal Amphotericin B
Intravitreal Amphotericin B

... Intravitreal Corticosteroids • Intravitreal corticosteroids (e.g., Dexamethasone 400 μg) may be a helpful adjunct in some patients with fungal endophthalmitis, by reducing inflammation. • Generally, corticosteroids should be withheld until proper antimicrobials have been initiated, especially in pa ...
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