IY12A Epirubicin inj pi jan12_1.ai
... • Bilirubin > 3 mg/dL or AST > 4 times upper limit of normal 1/4 of recommended starting dose Renal Impairment While no speci c dose recommendation can be made based on the limited available data in patients with renal impairment, consider lower doses in patients with severe renal impairment (serum ...
... • Bilirubin > 3 mg/dL or AST > 4 times upper limit of normal 1/4 of recommended starting dose Renal Impairment While no speci c dose recommendation can be made based on the limited available data in patients with renal impairment, consider lower doses in patients with severe renal impairment (serum ...
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... aspirin is a central mechanism for the prevention of vascular events and tumorigenesis. In this review we will discuss the clinical results related to the impact of aspirin on the risk of cancer. Then, we will explain in detail the pharmacology of aspirin at low and high doses in order to give a mec ...
... aspirin is a central mechanism for the prevention of vascular events and tumorigenesis. In this review we will discuss the clinical results related to the impact of aspirin on the risk of cancer. Then, we will explain in detail the pharmacology of aspirin at low and high doses in order to give a mec ...
ZIDOVUDINE (AZT) - IARC Monographs
... lymphoma of the B-cell type was seen in each group, and three cases of Kaposi sarcoma were seen in the group given placebo and two in the group given zidovudine. Moore et al. (1991a) analysed data from a prospective, observational multicentre study at 12 clinical sites in the USA of 1030 patients wi ...
... lymphoma of the B-cell type was seen in each group, and three cases of Kaposi sarcoma were seen in the group given placebo and two in the group given zidovudine. Moore et al. (1991a) analysed data from a prospective, observational multicentre study at 12 clinical sites in the USA of 1030 patients wi ...
Fentanyl - Induced cough - PathoPhysIology and PreventIon M C. T
... irritant cough receptors17. However, Lin et al showed that age has no effect on the incidence of cough21. 2. Ethnicity: Fentanyl-induced cough may be more evident in Asian population than European one16,22. Schapermeier and Hopf demonstrated that the incidence of cough following intravenous (IV) fen ...
... irritant cough receptors17. However, Lin et al showed that age has no effect on the incidence of cough21. 2. Ethnicity: Fentanyl-induced cough may be more evident in Asian population than European one16,22. Schapermeier and Hopf demonstrated that the incidence of cough following intravenous (IV) fen ...
CLARITIN® Rapid Dissolve
... Loratadine is a long-acting tricyclic antihistamine with selective peripheral H 1 receptor antagonistic activity. It exhibits a dose-related inhibition of the histamine-induced skin wheal and flare response in humans which is rapid in onset, is apparent at two hours and persists throughout the 24 ho ...
... Loratadine is a long-acting tricyclic antihistamine with selective peripheral H 1 receptor antagonistic activity. It exhibits a dose-related inhibition of the histamine-induced skin wheal and flare response in humans which is rapid in onset, is apparent at two hours and persists throughout the 24 ho ...
BREO ELLIPTA
... large placebo-controlled US trial that compared the safety of another LABA (salmeterol) with placebo added to usual asthma therapy showed an increase in asthma-related deaths in subjects receiving salmeterol. This finding with salmeterol is considered a class effect of LABA. Currently available data ...
... large placebo-controlled US trial that compared the safety of another LABA (salmeterol) with placebo added to usual asthma therapy showed an increase in asthma-related deaths in subjects receiving salmeterol. This finding with salmeterol is considered a class effect of LABA. Currently available data ...
a new antiarrhythmic compound potent class iii
... fibrillation of <90 days’ duration was higher (31% to 44%) with ibutilide (a dose of 0.015 mg/kg or 2 mg) compared with placebo19, sotalol (1.5 mg/kg)20, or procainamide 1200 mg21–23. In acute episodes with onset of 3 to 48 hrs, ibutilide has a higher efficacy in atrial flutter (87%) compared with a ...
... fibrillation of <90 days’ duration was higher (31% to 44%) with ibutilide (a dose of 0.015 mg/kg or 2 mg) compared with placebo19, sotalol (1.5 mg/kg)20, or procainamide 1200 mg21–23. In acute episodes with onset of 3 to 48 hrs, ibutilide has a higher efficacy in atrial flutter (87%) compared with a ...
Martindale: The Complete Drug Reference
... elderly patients after prolonged oral use,14,15 but it has been reported with short-term high-dose parenteral use as an antiemetic in cancer chemotherapy,16 and a case has been reported in an 8-year-old child treated with metoclopramide for gastrooesophageal reflux disease in usual doses.17 The aver ...
... elderly patients after prolonged oral use,14,15 but it has been reported with short-term high-dose parenteral use as an antiemetic in cancer chemotherapy,16 and a case has been reported in an 8-year-old child treated with metoclopramide for gastrooesophageal reflux disease in usual doses.17 The aver ...
Map and Application of States That Require a Prescription for
... isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labeled and marketed in a manner consistent with the pertinent United States Food and Drug Administr ...
... isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labeled and marketed in a manner consistent with the pertinent United States Food and Drug Administr ...
Map and Application of States That Require a Prescription for
... isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labeled and marketed in a manner consistent with the pertinent United States Food and Drug Administr ...
... isomer of ephedrine, or a salt of an optical isomer of ephedrine. Products listed below are exempted if they may belawfully sold over the counter without a prescription under the federal act, and are labeled and marketed in a manner consistent with the pertinent United States Food and Drug Administr ...
Gemcitabine 1g Powder for Solution for Infusion
... disease with 17 to 28% survival in phase III studies. Combination therapy (including gemcitabine) has demonstrated significantly better progression-free survival at 4 months. The clinical overview goes on to say that gemcitabine treatment has also been shown to result in a 17% remission rate in ovar ...
... disease with 17 to 28% survival in phase III studies. Combination therapy (including gemcitabine) has demonstrated significantly better progression-free survival at 4 months. The clinical overview goes on to say that gemcitabine treatment has also been shown to result in a 17% remission rate in ovar ...
Placebo Effects in Guidelines, Practice, and Patient Choice:
... For much of the modern era of medicine, the placebo has been largely viewed as a useful control in clinical trials. However, clinical research has demonstrated that placebo has powerful effects of its own. Despite this mounting evidence, providers rarely consider placebo effects in clinical manageme ...
... For much of the modern era of medicine, the placebo has been largely viewed as a useful control in clinical trials. However, clinical research has demonstrated that placebo has powerful effects of its own. Despite this mounting evidence, providers rarely consider placebo effects in clinical manageme ...
Trent Medicines Information Service
... Medicines Information Centre. Conflicts: try not to get caught up in patient conflicts with other professionals. All the published information sources that you use are in the public domain. Instinct: You may have to do what seems right to you. You do not have to answer everything that you are ...
... Medicines Information Centre. Conflicts: try not to get caught up in patient conflicts with other professionals. All the published information sources that you use are in the public domain. Instinct: You may have to do what seems right to you. You do not have to answer everything that you are ...
NCPDP Recommendations and Guidance for Standardizing the Dosing Designations on
... Dosing errors involving oral liquid medications administered by patients and caregivers in home settings have been a source of concern for many years. Of particular concern are medication errors involving young children, as they may be more susceptible to harm from measurement errors and overdoses. ...
... Dosing errors involving oral liquid medications administered by patients and caregivers in home settings have been a source of concern for many years. Of particular concern are medication errors involving young children, as they may be more susceptible to harm from measurement errors and overdoses. ...
A Review on Anthelmintic Plants
... of side effects. Crude drugs are less efficient with respect to cure of diseases but are relatively free from side effects. Parasites have been of concern to the medical field for centuries and the helminths considered causing considerable problems for human beings and animals. A large number of med ...
... of side effects. Crude drugs are less efficient with respect to cure of diseases but are relatively free from side effects. Parasites have been of concern to the medical field for centuries and the helminths considered causing considerable problems for human beings and animals. A large number of med ...
The Ergogenic Effects of Caffeine During Sport and Exercise
... caffeine withdrawal can do more harm than good. Most people bring up the point that caffeine has a diuretic effect that may lead an excessive passage of urine and dehydration. A very interesting study by Armstrong et. Al. (2005), concluded that there was no unusual levels of dehydration found after ...
... caffeine withdrawal can do more harm than good. Most people bring up the point that caffeine has a diuretic effect that may lead an excessive passage of urine and dehydration. A very interesting study by Armstrong et. Al. (2005), concluded that there was no unusual levels of dehydration found after ...
Pharmacogenetic Determinants of Codeine Induction by Rifampin
... rifampin dose and again 1 h after the last rifampin dose. On the morning of each study day and after an overnight fast and 24 h of abstention from caffeine-containing food and beverages, the subjects received a single 120-mg p.o. dose of codeine phosphate. Food was not permitted for the initial 6 h, ...
... rifampin dose and again 1 h after the last rifampin dose. On the morning of each study day and after an overnight fast and 24 h of abstention from caffeine-containing food and beverages, the subjects received a single 120-mg p.o. dose of codeine phosphate. Food was not permitted for the initial 6 h, ...
The Potential of Stimuli-Responsive Nanogels in Drug and Active
... solid and spherical structures, submicron-sized, prepared from polymeric materials and/or metallic compounds. NPs can be classified as nanocapsules (the active agent forms a matrix combined with the polymer-forming the NP) and nanospheres (the active agent constitutes the core surrounded by polymeri ...
... solid and spherical structures, submicron-sized, prepared from polymeric materials and/or metallic compounds. NPs can be classified as nanocapsules (the active agent forms a matrix combined with the polymer-forming the NP) and nanospheres (the active agent constitutes the core surrounded by polymeri ...
PART I B SUMMARY OF PRODUCT CHARACTERISTICS
... important that sensitivity testing be performed when prescribing clarithromycin for communityacquired pneumonia. In hospital-acquired pneumonia, clarithromycin should be used in combination with additional appropriate antibiotics. Skin and soft tissue infections of mild to moderate severity: These i ...
... important that sensitivity testing be performed when prescribing clarithromycin for communityacquired pneumonia. In hospital-acquired pneumonia, clarithromycin should be used in combination with additional appropriate antibiotics. Skin and soft tissue infections of mild to moderate severity: These i ...
Stability and aerosolization of pressurized metered dose inhalers
... were achieved. During storage, it was found that for all pMDIs more than 97% of the labeled amount of thymopentin and FPF greater than 47% were achieved. Moreover, the size of thymopentin nanoparticles in propellant containing cineole and n-heptane showed little change. It is, therefore, concluded t ...
... were achieved. During storage, it was found that for all pMDIs more than 97% of the labeled amount of thymopentin and FPF greater than 47% were achieved. Moreover, the size of thymopentin nanoparticles in propellant containing cineole and n-heptane showed little change. It is, therefore, concluded t ...
Which neuroreceptors mediate the subjective effects of MDMA in
... In preclinical studies, 3,4-methylenedioxymethamphetamine (MDMA, `Ecstasy') has been shown to release serotonin (5-HT), dopamine and norepinephrine. However, the role of these neurotransmitters and their corresponding receptor sites in mediating the subjective effects of MDMA has not yet been studie ...
... In preclinical studies, 3,4-methylenedioxymethamphetamine (MDMA, `Ecstasy') has been shown to release serotonin (5-HT), dopamine and norepinephrine. However, the role of these neurotransmitters and their corresponding receptor sites in mediating the subjective effects of MDMA has not yet been studie ...
Spreading of Semisolid Formulations: An Update
... Formulation characteristics. Formulation characteristics, including viscosity, elasticity, and rheology, are the most important factors in the development and final behavior of semisolid formulations. Increasing the viscosity of the delivery vehicle increases its retention time at the target site bu ...
... Formulation characteristics. Formulation characteristics, including viscosity, elasticity, and rheology, are the most important factors in the development and final behavior of semisolid formulations. Increasing the viscosity of the delivery vehicle increases its retention time at the target site bu ...
Subcutaneous Absorption of Biotherapeutics: Knowns and Unknowns
... higher Stokes-Einstein radius are transported faster than smaller solutes) (Reddy et al., 2006). The slower interstitial transport of small solutes does not necessarily lead to a slower absorption into systemic circulation, as small solutes can be absorbed into blood circulation rather than into the ...
... higher Stokes-Einstein radius are transported faster than smaller solutes) (Reddy et al., 2006). The slower interstitial transport of small solutes does not necessarily lead to a slower absorption into systemic circulation, as small solutes can be absorbed into blood circulation rather than into the ...
NLA Task Force On Statin Safety - 2014 Update
... but may approach 10%. Real or perceived symptoms from statins may be an underappreciated cause of nonadherence to therapy. Data from the cross-sectional Understanding Statin use in America and Gaps in Patient Education (USAGE) study suggests that muscle symptoms may occur in up to 29% of patients in ...
... but may approach 10%. Real or perceived symptoms from statins may be an underappreciated cause of nonadherence to therapy. Data from the cross-sectional Understanding Statin use in America and Gaps in Patient Education (USAGE) study suggests that muscle symptoms may occur in up to 29% of patients in ...