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Consensus Guidelines for the Management of
Consensus Guidelines for the Management of

... large cohort studies (Table 1). The most likely causes of PONV are volatile anesthetics, nitrous oxide, and postoperative opioids.21,22 The effect of volatile anesthetics on PONV is dose-dependent and particularly prominent in the first 2 to 6 hours after surgery.21 Irrespective of the specific drug ...
SCIENTIFIC DISCUSSION 1. Introduction
SCIENTIFIC DISCUSSION 1. Introduction

... clearly more effective than another and no single medication results in remission for all patients. In many occasions the choice of the medication is made looking at the side effect profile. The cyclic antidepressants are less commonly used as first-line antidepressants with the development of the S ...
Oxycodone-Naloxone Acino Prolonged
Oxycodone-Naloxone Acino Prolonged

... dose. Special attention should be given to patients with compromised renal function and patients with mild hepatic impairment if an increased dose is considered. For patients requiring higher doses of Oxycodone/Naloxone Acino, administration of supplemental prolonged-release oxycodone hydrochloride ...
Research Paper Synthesis and Evaluation of Clozapine
Research Paper Synthesis and Evaluation of Clozapine

... Pharmacological Evaluation Evaluation of Neuropharmacological activity Clozapine is an antipsychotic drug act by decreasing the levels of dopamine, by antagonizing the dopamine receptors in central nervous system. It binds to not only dopamine receptors but also to various receptors in brain and eli ...
Full-Text PDF
Full-Text PDF

... Poor solubility is one of the main problems faced by researchers during drug development. Commonly, even with the use of current computational “filters” to minimize this problem, compounds that are active in vitro may lack adequate pharmacokinetic properties and/or may be difficult to formulate [1]. ...
Queensland Opioid Treatment Program: Clinical Guidelines 2012
Queensland Opioid Treatment Program: Clinical Guidelines 2012

... opioid dependence. These guidelines are expected to be reviewed in three years by the Queensland Opioid Treatment Reference Group to ensure they continue to reflect current best practice. For the purpose of this document, buprenorphine will refer to both buprenorphine mono (Subutex®) and buprenorphi ...
Provider Manual - 1199SEIU Funds
Provider Manual - 1199SEIU Funds

... • Lower administrative costs with electronic claims processing; • No deductibles and no co-payments for participants in the 1199SEIU National Benefit Fund for Health and Human Service Employees, and minimal co-payments for participants in the 1199SEIU Greater New York Benefit Fund and the 1199SEIU ...
Enhancing the Delivery of Resveratrol in Humans
Enhancing the Delivery of Resveratrol in Humans

... offers comparisons regarding the pharmacokinetics of resveratrol between human studies. The greatest Cmax and AUC of free trans-resveratrol have been observed following the largest dosages, generally 5 g per day [23,45,54]. These doses demonstrate that a Cmax of approximately 4 µM is attainable in h ...
Mepivacaine - Academy of General Dentistry
Mepivacaine - Academy of General Dentistry

... the introduction of articaine—in 1982 in Canada and in 2000 in the US—has gained much of the market share in North America, lidocaine and mepivacaine have remained commonly used agents.1 In Canada, where articaine is the most used agent, a survey of general dentists showed that from 1993 to 2007, me ...
Buprenorphine Prescribing Information
Buprenorphine Prescribing Information

... visits. Provision of multiple refills is not advised early in treatment or without appropriate patient follow-up visits. Periodic assessment is necessary to determine compliance with the dosing regimen, effectiveness of the treatment plan, and overall patient progress. Once a stable dosage has been ...
Queensland Opioid Treatment Program: Clinical Guidelines 2012 Queensland Health
Queensland Opioid Treatment Program: Clinical Guidelines 2012 Queensland Health

... opioid dependence. These guidelines are expected to be reviewed in three years by the Queensland Opioid Treatment Reference Group to ensure they continue to reflect current best practice. For the purpose of this document, buprenorphine will refer to both buprenorphine mono (Subutex®) and buprenorphin ...
Neurologic Effects of Caffeine - Health301Co
Neurologic Effects of Caffeine - Health301Co

... to stimuli with a specified color (red or blue) in order to react to the occurrence of a target ...
DOXOrubicin vials - Sagent Pharmaceuticals
DOXOrubicin vials - Sagent Pharmaceuticals

... contractions, and ventricular tachycardia, as well as bradycardia may occur. Electrocardiographic changes including non-specific ST-T wave changes, atrioventricular and bundle-branch block can also occur. These electrocardiographic changes may be transient and self-limited and may not require dose-m ...
Greater Sensitivity to Subjective Effects of Nicotine in Nonsmokers
Greater Sensitivity to Subjective Effects of Nicotine in Nonsmokers

... animal research is consistent with this notion. Mice exhibiting greater nicotine-induced locomotor activity also show greater conditioned place preference to nicotine (Schechter, Meehan, & Schechter, 1995), which may relate to nicotine's pleasurable effects. Moreover, genetic control of initial sens ...
Carbamazepine ER Capsules, 300 mg 120 count
Carbamazepine ER Capsules, 300 mg 120 count

... measurement of drug serum levels may aid in determining the cause of toxicity when more than one medication is being used. ...
Potential applications of chitosan in veterinary medicine
Potential applications of chitosan in veterinary medicine

... A variety of chitosan-based colloidal delivery systems have been described in the literature for the mucosal delivery of polar drugs, peptides, proteins, vaccines and DNA. Clinical tests carried out in order to promote chitosan-based biomaterials do not report any inflammatory or allergic reactions ...
MS_Word ~ 273 KB
MS_Word ~ 273 KB

... although selection bias is a confounding issue given fever is an indication for paracetamol therapy. Animal studies indicate fever influences the metabolism of paracetamol and detoxification of the toxic intermediate metabolite (10). Unwell children receiving multiple doses of paracetamol appear to ...
Intracranial Self-Stimulation to Evaluate Abuse Potential of Drugs
Intracranial Self-Stimulation to Evaluate Abuse Potential of Drugs

... evaluation of both abuse-related and abuse-limiting effects, 2) flexibility for use with various routes of drug administration or drug vehicles, 3) utility for studies in drug-naive subjects as well as in subjects with controlled levels of prior drug exposure, and 4) utility for studies of drug time ...
product monograph
product monograph

... determination of the patient's antithrombin III activity prior to therapy and thereafter at intervals of approximately 4-6 hours. The initial dose should be large enough to raise the plasma level to normal (80-120%). Additional doses are required whenever the antithrombin III activity has dropped to ...
Buprenorphine (with or without naloxone)
Buprenorphine (with or without naloxone)

... pharmacy than does the liquid methadone formulation (Chadderton 2000). Alternateday dosing may compensate for this extra time. Tablets can also be more easily diverted than liquids, because of their longer absorption time. Buprenorphine is safer in overdose Buprenorphine has a better safety profile ...
Effects of grapefruit juice on the pharmacokinetics of selected
Effects of grapefruit juice on the pharmacokinetics of selected

... protein, it participates in the biotransformation of a range of widely used drugs such as tricyclic antidepressants, neuroleptics, and β-blockers (Cholerton et al. 1992). CYP2D6 is not inducible, but can be inhibited by such drugs as quinidine, paroxetine and fluoxetine (Inaba et al. 1986; ...
SNOMED CT® UK Drug Extension Editorial Policy
SNOMED CT® UK Drug Extension Editorial Policy

... stored. Prior to dm+d there has been no common, standardised vocabulary for medicinal products. Lack of standardisation does not allow interoperability between diverse clinical systems, or allow effective decision support through linkage of data. The case for change is driven at a strategic level by ...
DOC - Investor Relations
DOC - Investor Relations

... some cases, these forward-looking statements can be identified by the use of forward-looking terminology, including the terms “believes,” “estimates,” “anticipates,” “expects,” “plans,” “intends,” “may,” “could,” “might,” “will,” “should,” “approximately” or, in each case, their negative or other va ...
CIPRO XL PRODUCT MONOGRAPH
CIPRO XL PRODUCT MONOGRAPH

... shortness of breath and acute respiratory distress), dyspnea, urticaria, itching and other serious skin reactions. CIPRO XL should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity. Serious acute hypersensitivity reactions may require treatment with epineph ...
product monograph
product monograph

... General: Sympathomimetics should be used with caution in patients with stenosing peptic ulcer, pyloroduodenal obstruction, prostatic hypertrophy or bladder neck obstruction, cardiovascular disease, increased intraocular pressure or diabetes mellitus. Sympathomimetics should be used with caution in p ...
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