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NCCT2005 - That Crazy Pharmacist
NCCT2005 - That Crazy Pharmacist

... cancer therapy because the scientific approach was lacking. Second, the modern physician needs to serve patients who are sorting through more information than ever before. With this book, the value of using natural compounds in cancer therapy will gain new respect because it makes the scientific fra ...
Boik-Natural-Compounds-in-Cancer-Therapy-Promising
Boik-Natural-Compounds-in-Cancer-Therapy-Promising

... cancer therapy because the scientific approach was lacking. Second, the modern physician needs to serve patients who are sorting through more information than ever before. With this book, the value of using natural compounds in cancer therapy will gain new respect because it makes the scientific fra ...
AusPAR: Dapagliflozin - Therapeutic Goods Administration
AusPAR: Dapagliflozin - Therapeutic Goods Administration

... © Commonwealth of Australia 2014 This work is copyright. You may reproduce the whole or part of this work in unaltered form for your own personal use or, if you are part of an organisation, for internal use within your organisation, but only if you or your organisation do not use the reproduction fo ...
DBL™ PIPERACILLIN AND TAZOBACTAM FOR INJECTION 2 g
DBL™ PIPERACILLIN AND TAZOBACTAM FOR INJECTION 2 g

... associated with a cephalosporin or penicillin treatment. Past history of a severe allergic reaction to penicillin/ cephalosporin is a contraindication to the use of Piperacillin/tazobactam. Before initiating therapy with any penicillin/ cephalosporin, careful inquiry should be made concerning previo ...
Otezla - Celgene
Otezla - Celgene

... who have been intolerant to a prior DMARD therapy, or who have a contraindication to a DMARD therapy. Otezla has been shown to improve physical function. Psoriasis: Otezla is indicated for the treatment of adult patients with moderate to severe plaque psoriasis (PSOR) who are candidates for photothe ...
Drug interactions involving warfarin
Drug interactions involving warfarin

... Development of the practice tool The practice tool for drug interactions involving warfarin presented here was originally developed by a single practitioner (T.J.B.) working in an anticoagulation management service, who began charting common interactions between warfarin and other prescription drugs ...
amoxicillin: a broad spectrum antibiotic
amoxicillin: a broad spectrum antibiotic

... degradation  was  subject  to  catalysis  by  phosphate  and  citrate  buffers  with  a  10  fold  increase  in  rate  with  phosphate.  Increasing  ionic  strength  was  reported  to  have  positive  effect  on  degradation  rate in alkali and a negative effect in acid25.  At higher concentration a ...
voriconazole - Therapeutic Goods Administration
voriconazole - Therapeutic Goods Administration

... In patients with moderate to severe renal dysfunction (creatinine clearance <50 mL/min), accumulation of the intravenous vehicle, SBECD, occurs. Oral voriconazole should be administered to patients with moderate to severe renal dysfunction including dialysis patients, unless an assessment of the ben ...
Does High-Dose Buprenorphine Cause Respiratory Depression
Does High-Dose Buprenorphine Cause Respiratory Depression

... norbuprenorphine-induced respiratory depression (figure 2). In animals, significant protective effect was observed even when norbuprenorphine exceeded buprenorphine concentrations in plasma,[43] whereas in the majority of reported human fatalities, buprenorphine exceeded norbuprenorphine concentrati ...
Appendix 2: Underpinning Scientific Knowledge 2015
Appendix 2: Underpinning Scientific Knowledge 2015

... Relevant cell types including T cells (CD4 and CD8), B cells, dendritic cells. Antibodies. Immune tolerance; self/non-self, danger hypothesis. MHC class I and II. Immunomodulation, including co-stimulation and negative regulation. Tumour associated antigens. Immune suppression by tumours; tumour inf ...
2009 St Johns Wort Quality Issues and Active Compounds
2009 St Johns Wort Quality Issues and Active Compounds

... Nielsen et al. and Baureithel et al. focused their investigations on the bifl avone amento-fl avone, which bound to the brain benzodiazepine receptors with an affi nity comparable to diazepam (18, 19). However, the fl avonoids rutin, hyperoside, and quercitrin did not inhibit benzodiazepine binding ...
Mechanistic Studies on Metabolic Interactions between Gemfibrozil
Mechanistic Studies on Metabolic Interactions between Gemfibrozil

... NMR spectroscopy (Prueksaritanont et al., 1999). Brij 58, alamethicin, GFZ, clofibric acid, and UDPGA were obtained from SigmaAldrich (St. Louis, MO). Sulfaphenazole and ketoconazole were purchased from Ultrafine (Manchester, England) and Research Diagnostics (Flanders, NJ), respectively. All other ...
New Zealand Practice Guidelines for Opioid
New Zealand Practice Guidelines for Opioid

... are free to: share ie, copy and redistribute the material in any medium or format; adapt ie, remix, transform and build upon the material. You must give appropriate credit, provide a link to the licence and indicate if changes were made. ...
New Zealand Practice Guidelines for Opioid Substitution Treatment
New Zealand Practice Guidelines for Opioid Substitution Treatment

... are free to: share ie, copy and redistribute the material in any medium or format; adapt ie, remix, transform and build upon the material. You must give appropriate credit, provide a link to the licence and indicate if changes were made. ...
Australian public assessment report for Dolutegravir (as sodium)
Australian public assessment report for Dolutegravir (as sodium)

... required for HIV replication. Two INIs, raltegravir (RAL) and elvitegravir (EVG), have proved effective and have been approved for use in combination with other ART. However, new therapies continue to be required because of long term drug toxicities and the emergence of drug resistant HIV strains. R ...
Newly Formed Reticulated Platelets Undermine Pharmacokinetically
Newly Formed Reticulated Platelets Undermine Pharmacokinetically

... received DAPT comprising either aspirin+clopidogrel or aspirin+ticagrelor. Patients were assessed for pharmacological efficacy by testing of platelet reactivity using light transmission aggregometry. All patients had a final aggregation to ADP (20 μmol/L) of <43%, with those receiving ticagrelor con ...
Diphenhydramine versus nonsedating antihistamines for acute
Diphenhydramine versus nonsedating antihistamines for acute

... First-generation antihistamines can have adverse effects on the central nervous system and thereby complicate discharge planning from the emergency department (ED). Newer antihistamines are potentially safer, causing less sedation with similar efficacy. The aim of this study was to review the litera ...
Insect repellents
Insect repellents

... (other than a food or device) intended for use in the diagnosis, cure, relief, treatment, or prevention of disease or intended to affect the structure or function of the body.  A simpler but workable definition of a drug is any chemical substance that affects the body and its processes. ...
TCCC Change Prop 1403 Ondansetron 150403 JSOM
TCCC Change Prop 1403 Ondansetron 150403 JSOM

... Additionally, information was obtained from the FDA website and some general drug information was obtained from open-source pharmacology websites. DISCUSSION POINTS The Case against promethazine Promethazine is an H1-receptor blocking agent that also has sedative and antiemetic effects along with it ...
Aminoglycoside
Aminoglycoside

... appropriate for current microbiologic cultures and sensitivities. Also, it should be confirmed that the patient is receiving other appropriate concurrent antibiotic therapy, such as β-lactam or anaerobic agents, when necessary to treat the infection. Patients with severe infections usually have eleva ...
COMPARATIVE EVALUATION OF NATURAL AND SYNTHETIC SUPERDISINTEGRANT FOR  PROMOTING NIMESULIDE DISSOLUTION FOR FAST DISSOLVING TECHNOLOGY 
COMPARATIVE EVALUATION OF NATURAL AND SYNTHETIC SUPERDISINTEGRANT FOR  PROMOTING NIMESULIDE DISSOLUTION FOR FAST DISSOLVING TECHNOLOGY 

... uses  have  been  found  in  the  preparation  of  cosmetics,  textiles,  and  paint  paper.  Mucilage  of  natural  origin  is  preferred  over  synthetic  and  semisynthetic  agent  because  they  are  cheaper,  abundantly  available,  nontoxic  and  nonirritating  in  nature.  Lepidium  sativum  ...
Central Nervous System Permeation of Non
Central Nervous System Permeation of Non

... acting in both the peripheral tissues and the central nervous system (CNS). However, knowledge on CNS permeation of these drugs in children in sparse. Therefore cerebrospinal fluid (CSF) penetration of diclofenac, ibuprofen, indomethacin, ketorolac, and paracetamol was studied in 160 healthy childre ...
Medicated Chewing Gum- A Mobile Oral Drug Delivery System
Medicated Chewing Gum- A Mobile Oral Drug Delivery System

... Gums formed using compressible formulation are 10 times harder and crumble when pressure is applied resulting in faster release than conventional methods. The limitations of conventional manufacturing methods for medicated chewing gum such as melting & freezing can be overcome by the use of directly ...
PHYTOCHEMICAL, BIOLOGICAL AND TOXICOLOGICAL STUDIES
PHYTOCHEMICAL, BIOLOGICAL AND TOXICOLOGICAL STUDIES

... This is to certify that Mrs. OGUNLANA Olubanke Olujoke (Matric No: CUGP070176) carried out this research work in partial fulfillment of the requirements for the award of Doctor of Philosophy (Ph.D.) degree in Biochemistry of Covenant University, Ota, under our supervision. ...
BAX 855, a PEGylated rFVIII product with prolonged half-life
BAX 855, a PEGylated rFVIII product with prolonged half-life

... also demonstrated an excellent lot to lot consistency with regard to PEGylation site distribution. Detailed biochemical characterization further showed that PEGylated FVIII retained all the physiological functions of the FVIII molecule with the exception of binding to the LRP clearance receptor whic ...
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