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Tick-Borne Encephalitis vaccine
Tick-Borne Encephalitis vaccine

... Adverse reactions should be reported even if it is not certain that the vaccine caused it, if it is well recognised, or if other drugs were given at the same time. TBE vaccination is unlikely to affect a person's ability to drive and use machines. It should be taken into account, however, that impa ...
Vertina Plus
Vertina Plus

... Meclizine HCl: Pregnancy category B. Large-scale human studies have not demonstrated adverse fetal effects. It has been suggested that, based on available data, Meclizine HCl presents the lowest risk of teratogenicity and is the drug of first choice in treating nausea and vomiting during pregnancy. ...
2014 Evidence-Based Guideline for the Management of High Blood
2014 Evidence-Based Guideline for the Management of High Blood

... (2) The study had at least 2000 participants. (3) The study was multicentered. (4) The study met all the other inclusion/exclusion criteria. The relatively high threshold of 2000 participants was used because of the markedly lower event rates observed in recent RCTs such as ACCORD, suggesting that l ...
Drugs Used In Peptic Ulcer and Eradication Therapy
Drugs Used In Peptic Ulcer and Eradication Therapy

... In (GU) one half of the patient’s vagactomy (cutting out of the vagus nerve which is responsible for stimulation of the acid production), required, if the conservative treatment fails. ...
here - Zoetis
here - Zoetis

... These side effects are transitory, lasting from 10 minutes to 3 hours, and were not detrimental to the health of the animal. Mares: The most frequently observed side effects are sweating and decreased rectal temperature. However, these have been transient in all cases observed and have not been detr ...
LETTERS
LETTERS

... We found the highest hypertension rate with rofecoxib (25 mg). The rate with rofecoxib (12.5 mg) was not significantly different than with placebo or nonselective NSAIDs. We found no differences between celecoxib (200 mg) and placebo or nonselective NSAID controls in the rates of hypertension. Our r ...
RUBOXISTAURIN – A PROMISING THERAPY FOR DIABETIC
RUBOXISTAURIN – A PROMISING THERAPY FOR DIABETIC

... domains that can bind to DAG. This results in the activation of PKCβ, which can lead to the increased expression of cycloxygenase, decreased production of the vasodilator prostacyclin and increased production of thromboxane A2,[6] decreased nitric oxide production and increased endothelin-1 (ET-1) p ...
Can breastfeeding mothers take ibuprofen?
Can breastfeeding mothers take ibuprofen?

... pain including dysmenorrhoea, postoperative analgesia, dental pain and migraine (1). It can also be given to infants aged 1–3 months at a dose of 5mg/kg body weight 3–4 times daily for pain, inflammation of soft-tissue injuries, and pyrexia (2), although this is off-label under 3 months. Ibuprofen c ...
Topamax Master PI
Topamax Master PI

... double-blind, placebo-controlled trials, two comparing several dosages of topiramate and placebo and three comparing a single dosage with placebo, in patients with a history of partial onset seizures, with or without secondarily generalized seizures. Patients in these studies were permitted a maximu ...
Seretide PI - GSK Australia
Seretide PI - GSK Australia

... In vitro tests have shown salmeterol is a potent and long-lasting inhibitor of the release of mast cell mediators, such as histamine, leukotrienes and prostaglandin D2, from human lung fragments. In one study in man, salmeterol inhibits the early and late phase response to inhaled allergen; the latt ...
Pentazocine - e-SAFE
Pentazocine - e-SAFE

... not seen in normal patients or in patients ventilated after a head injury, suggesting that mild respiratory depression with an associated intracranial vasodilatation from a rise in PaCO2 may be the underlying cause. Arterial or pulmonary hypertension Pentazocine increases both heart rate and systoli ...
Conversions of Strong Opiates
Conversions of Strong Opiates

... Convert to total oral daily dose, then PRN for total  Fentanyl patch 75mcg/hour equivalent oral Morphine 270mg/24hours  Morphine sc infusion 60mg/24 hours Equivalent oral Morphine 120mg/24hours  Total equivalent oral Morphine dose 390mg/24hours  PRN oral Morphine 60mg  PRN sc Morphine 30mg ...
QA248_4Pyridostigmine_neostigmine_FINAL
QA248_4Pyridostigmine_neostigmine_FINAL

... The dose of pyridostigmine can vary from 30 - 120mg every 3-4 hours, with between 5-20 tablets taken daily.(2) The total daily dose of parenteral neostigmine can vary between 5-20mg, with 1-2.5mg given by IM or SC injection every 2-4 hours.(3) Oral neostigmine doses are usually 15 – 30mg at regular ...
DIOSPYROS MELANOXYLON
DIOSPYROS MELANOXYLON

... Diospyros melanoxylon bark. The maximum tolerated dose was found to be 2000 mg/kg b.w when the extract was administered orally. As per the OECD (International toxicity testing) guidelines the maximum therapeutic dose is 1/10th of maximum tolerated dose, hence the therapeutic dose selected for the ex ...
Maximizing the Use of Single
Maximizing the Use of Single

... Medications to Prevent Healthcareassociated Infections. CMS Office of Clinical Standards and Quality/Survey & Certification Group, June 15, 2012 Ref: S&C: 1235-ALL – Under certain conditions, it is permissible to repackage single-dose vials or single use vials (collectively referred to in this memor ...
Role of antiarrhythmic drugs: frequent implantable cardioverter
Role of antiarrhythmic drugs: frequent implantable cardioverter

... decrease in the incidence of all ICD interventions and all-cause shocks with an increased inter-event interval suggesting a possible benefit in the treatment of electrical storm. This was confirmed by subsequent analysis of SHEILD data by Hohnloser et al who showed that treatment with 75 mg and 125 ...
A  comparison  of  the  cardiovascular ... formoterol,  salbutamol  and  fenoterol
A comparison of the cardiovascular ... formoterol, salbutamol and fenoterol

... changes noted in this study are primarily due to stimulation of myocardial beta-receptors, an alternative explanation could be that they are due to inhalation of high doses of freons from inhalers. However this is unlikely for a number of reasons. Firstly, freons alone tend to cause depression of ch ...
Product Monograph - Ask Novartis Pharma
Product Monograph - Ask Novartis Pharma

... Adverse Drug Reaction Overview Adverse reactions with AREDIA® (pamidronate disodium) are usually mild and transient. The most common adverse reactions are influenza-like symptoms and mild fever (an increase in body temperature of >1°C, which may last up to 48 hours). Fever usually resolves spontaneo ...
Newly Approved Anticoagulants
Newly Approved Anticoagulants

... Loss of function, results in increased sensitivity to warfarin and increased potential for drug interactions because VKORC1 does not function normally to produce vitamin K dependent clotting factors (II, VII, IX, X, proteins C and S) – 37% of Caucasians, 14% of AAs, 89% of Asians have at least one v ...
Imlygic : EPAR - EMA
Imlygic : EPAR - EMA

... Authorisation to the European Medicines Agency (EMA) for Imlygic, through the centralised procedure falling within the Article 3(1) and point 1 of Annex of Regulation (EC) No 726/2004. The applicant applied for the following indication treatment of adults with melanoma that is regionally or distantl ...
design and development of lornoxicam fast dissolving tablets by
design and development of lornoxicam fast dissolving tablets by

... Fast dissolving tablets (FDT) are designed for the purpose of improving patient acceptance and compliance. A survey of 6158 GP patients conducted in Norway indicated that approximately 26% of all patients do not take their prescribed medication as they encountered problems when swallowing conventio ...
Sedation and Analgesia for Procedures
Sedation and Analgesia for Procedures

... on the American Society of Anesthesiologists (ASA) "Guidelines for Sedation and Analgesia by Non-Anesthesiologists." The standards also state that "individuals administering moderate or deep sedation and anesthesia are qualified and have the appropriate credentials to manage patients at whatever lev ...
(Cannabis genus) for use as animal feed
(Cannabis genus) for use as animal feed

... studies by Beal et al. (1995, 1997), in which HIV patients received oral THC. The first study was a placebo controlled study with 139 patients, who received either THC (2 x 2.5 mg/person daily) or placebo for 42 days (Beal et al. 1995). The second study was an open long-term study, where patients re ...
Prevention of Bleomycin-Induced Lung Inflammation and Fibrosis in
Prevention of Bleomycin-Induced Lung Inflammation and Fibrosis in

... tissue matrix, especially collagen, and the fibrosis becomes established (du Bois, 2010). This results in progressive airway stiffening and thickening of the air-blood membrane, which makes breathing difficult and eventually leads to respiratory failure. Compelling evidence suggests that inflammator ...
NIH Public Access
NIH Public Access

... New England Journal of Medicine in June 1948 3, was greeted with great enthusiasm when this agent was shown to produce, for the first time, remissions in children with acute lymphoblastic leukemia. While these remissions were short-lived, the activity of this agent established that this disease was ...
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