Aripiprazole LAI Prescribing Guidelines
... of schizophrenia in adult patients stabilised with oral aripiprazole. 2. Aripiprazole LAI may not be used for treatment-resistant schizophrenia, unlicensed indications or service users intolerant to or unresponsive oral aripiprazole. 3. Aripiprazole LAI may ONLY be newly prescribed by consultant psy ...
... of schizophrenia in adult patients stabilised with oral aripiprazole. 2. Aripiprazole LAI may not be used for treatment-resistant schizophrenia, unlicensed indications or service users intolerant to or unresponsive oral aripiprazole. 3. Aripiprazole LAI may ONLY be newly prescribed by consultant psy ...
Naltrexone potentiates anti-HIV-1 activity of antiretroviral drugs in
... presence of AZT (10 − 9 M), opiate receptor antagonists, or combinations of opiate receptor antagonists plus AZT, at indicated concentrations, for 4 days at which time supernatants were collected for measurement of p24 Ag levels. Data (mean 9 S.E.M. of three separate experiments using CD4+ lymphocyt ...
... presence of AZT (10 − 9 M), opiate receptor antagonists, or combinations of opiate receptor antagonists plus AZT, at indicated concentrations, for 4 days at which time supernatants were collected for measurement of p24 Ag levels. Data (mean 9 S.E.M. of three separate experiments using CD4+ lymphocyt ...
Newer Antihistamines
... fexofenadine 180 mg, loratadine 10 mg, or chlorpheniramine 8 mg to 21 men (7 in each group). Before dosing and at 1, 3, 6, 9, and 24 hours after the first antihistamine dose as well as at 168, 192, and 216 hours after the first dose (ie, 12, 36, and 60 hours after the seventh and last consecutive da ...
... fexofenadine 180 mg, loratadine 10 mg, or chlorpheniramine 8 mg to 21 men (7 in each group). Before dosing and at 1, 3, 6, 9, and 24 hours after the first antihistamine dose as well as at 168, 192, and 216 hours after the first dose (ie, 12, 36, and 60 hours after the seventh and last consecutive da ...
Full Prescribing Information
... treatment, prompt ophthalmologic evaluation is warranted. Since intracranial pressure can remain elevated for weeks after drug cessation patients should be monitored until they stabilize. ...
... treatment, prompt ophthalmologic evaluation is warranted. Since intracranial pressure can remain elevated for weeks after drug cessation patients should be monitored until they stabilize. ...
Glucophage (metformin)
... The onset of lactic acidosis often is subtle, and accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, increasing somnolence and non-specific abdominal distress. There may be associated hypothermia, hypotension and resistance bradyarrhythmias with more marked aci ...
... The onset of lactic acidosis often is subtle, and accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, increasing somnolence and non-specific abdominal distress. There may be associated hypothermia, hypotension and resistance bradyarrhythmias with more marked aci ...
Product Monograph Template - Standard - GlaxoSmithKline
... • The dosage of ZOVIRAX® (acyclovir) should be reduced in patients with impaired renal function. • Therapy should be initiated as soon as possible after a diagnosis of chickenpox or herpes zoster, or at the first sign or symptoms of an outbreak of genital herpes. • The recommended dose and duration ...
... • The dosage of ZOVIRAX® (acyclovir) should be reduced in patients with impaired renal function. • Therapy should be initiated as soon as possible after a diagnosis of chickenpox or herpes zoster, or at the first sign or symptoms of an outbreak of genital herpes. • The recommended dose and duration ...
Mucoadhesive Buccal Films Embedded with Antiviral Drug Loaded
... time etc (5-7). In this context, polymeric nanoparticles impregnated buccal films have been extensively studied and proved to be an effective approach to enhance bioavailability of drug molecules in addition to its potential to provide sustained release over an extended period of time (8). Recently, ...
... time etc (5-7). In this context, polymeric nanoparticles impregnated buccal films have been extensively studied and proved to be an effective approach to enhance bioavailability of drug molecules in addition to its potential to provide sustained release over an extended period of time (8). Recently, ...
London New Drugs Group / London Medicines Evaluation Network
... Dapoxetine is the first oral treatment for premature ejaculation (PE) to be licensed in the UK. It is a short-acting SSRI which can be taken when required up to 1-3 hours prior to anticipated sexual intercourse, no more than once a day. It is not intended for continuous daily dosing and should only ...
... Dapoxetine is the first oral treatment for premature ejaculation (PE) to be licensed in the UK. It is a short-acting SSRI which can be taken when required up to 1-3 hours prior to anticipated sexual intercourse, no more than once a day. It is not intended for continuous daily dosing and should only ...
topamax - Janssen
... with long term administration of TOPAMAX as monotherapy. There was no significant change in dosage during the extension period and no indication that effectiveness of TOPAMAX monotherapy diminished with continued exposure. The safety profile of TOPAMAX in monotherapy trials is consistent with that o ...
... with long term administration of TOPAMAX as monotherapy. There was no significant change in dosage during the extension period and no indication that effectiveness of TOPAMAX monotherapy diminished with continued exposure. The safety profile of TOPAMAX in monotherapy trials is consistent with that o ...
This copy is for personal use only
... Materials and methods: Limbic (psychomotor) seizure activity was evoked in albino Swiss mice by a current (32 mA, 6 Hz, 3 s stimulus duration) delivered via ocular electrodes. Isobolographic analysis for parallel dose-response relationship curves (DRRCs) was used to characterize the consequent antic ...
... Materials and methods: Limbic (psychomotor) seizure activity was evoked in albino Swiss mice by a current (32 mA, 6 Hz, 3 s stimulus duration) delivered via ocular electrodes. Isobolographic analysis for parallel dose-response relationship curves (DRRCs) was used to characterize the consequent antic ...
CIPRODEX ® Suspension
... and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones. Serious acute hypersensitivity reactions may require immediate emergency treatment. ...
... and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones. Serious acute hypersensitivity reactions may require immediate emergency treatment. ...
Postoperative nausea and vomiting
... should not be administered in men or women with QTc intervals above 440 ms or above 450 ms, respectively [14]. Therefore, care should be taken in administering this drug to patients with QTc prolongation before surgery. ...
... should not be administered in men or women with QTc intervals above 440 ms or above 450 ms, respectively [14]. Therefore, care should be taken in administering this drug to patients with QTc prolongation before surgery. ...
Asthma Technology
... PDL has completed a phase II clinical study testing Zenapax in a patient population suffering from chronic persistent asthma poorly controlled by inhaled corticosteriods. The phase II randomized, double blind, placebo-controlled multi-center clinical trial treated 114 patients. The clinical study de ...
... PDL has completed a phase II clinical study testing Zenapax in a patient population suffering from chronic persistent asthma poorly controlled by inhaled corticosteriods. The phase II randomized, double blind, placebo-controlled multi-center clinical trial treated 114 patients. The clinical study de ...
CLSI 2014 AST Update - Log into your Online Media Solutions portal
... Angeles, CA. She has written and taught extensively in the area of antimicrobial susceptibility testing. From 20002004 she held a contract with the Centers for Disease Control and Prevention (CDC) where her focus was to develop and conduct training programs in antimicrobial susceptibility testing. M ...
... Angeles, CA. She has written and taught extensively in the area of antimicrobial susceptibility testing. From 20002004 she held a contract with the Centers for Disease Control and Prevention (CDC) where her focus was to develop and conduct training programs in antimicrobial susceptibility testing. M ...
Ketamine has been designated a ‘red’ drug in Gwent and... recommended to be prescribed by non-specialists
... Changing patients from subcutaneous to oral ketamine Ketamine has pharmacokinetic and pharmacodynamic peculiarities. The bioavailabilty of oral ketamine has been reported to be 15%. PO ketamine undergoes extensive first-pass metabolism to norketamine (via CYP3A4). As an anaesthetic, norketamine is a ...
... Changing patients from subcutaneous to oral ketamine Ketamine has pharmacokinetic and pharmacodynamic peculiarities. The bioavailabilty of oral ketamine has been reported to be 15%. PO ketamine undergoes extensive first-pass metabolism to norketamine (via CYP3A4). As an anaesthetic, norketamine is a ...
Cough and Angioedema in Patients Receiving Angiotensin
... Although these treatments have been recommended by international guidelines, (1, 6) the long-term effectiveness is uncertain, particularly in terms of safety. (22) In this sense, it may be reasonable to switch to an angiotensin-II receptor blocker (ARB). ACEI-related angioedema does not have a speci ...
... Although these treatments have been recommended by international guidelines, (1, 6) the long-term effectiveness is uncertain, particularly in terms of safety. (22) In this sense, it may be reasonable to switch to an angiotensin-II receptor blocker (ARB). ACEI-related angioedema does not have a speci ...
Newer Agents for the Management of Overactive Bladder
... weeks, patients treated with trospium experienced between 1.5 and 4.0 fewer incontinence episodes per week than those treated with placebo and had a greater improvement in quality of life. However, these modest results were tempered by an increased incidence of anticholinergic adverse events. In add ...
... weeks, patients treated with trospium experienced between 1.5 and 4.0 fewer incontinence episodes per week than those treated with placebo and had a greater improvement in quality of life. However, these modest results were tempered by an increased incidence of anticholinergic adverse events. In add ...
Drug allergy – diagnosis and management: briefing paper
... adults, young people and children. It will not cover treatment of the acute phase including anaphylaxis, because this will be covered by a separate quality standard. ...
... adults, young people and children. It will not cover treatment of the acute phase including anaphylaxis, because this will be covered by a separate quality standard. ...
Prescribing - North Essex Partnership University NHS Foundation
... reverse of the PMAC to specify how many days’ medication is required and which, if any, when required medicines are to be supplied. This is only necessary if the patient is an overdose risk requiring a specific quantity of medication. 5.6.3. For discharge, a 24 hour discharge form should be complete ...
... reverse of the PMAC to specify how many days’ medication is required and which, if any, when required medicines are to be supplied. This is only necessary if the patient is an overdose risk requiring a specific quantity of medication. 5.6.3. For discharge, a 24 hour discharge form should be complete ...
... (temperature of 22 1°C with an alternating 12 h light– dark cycle and relative humidity of 60 5 %), one week before the start and also during the experiment as per the rules and regulations of the Institutional Animal Ethics committee and by the Regulatory body of the government (Regd no. 516/01 ...
Strattera - Eli Lilly and Company
... dose of approximately 0.5 mg/kg and increased after a minimum of 3 days to a target total daily dose of approximately 1.2 mg/kg administered either as a single daily dose in the morning or as evenly divided doses in the morning and late afternoon/early evening. No additional benefit has been demonst ...
... dose of approximately 0.5 mg/kg and increased after a minimum of 3 days to a target total daily dose of approximately 1.2 mg/kg administered either as a single daily dose in the morning or as evenly divided doses in the morning and late afternoon/early evening. No additional benefit has been demonst ...
DESIGN AND DEVELOPMENT OF MUCOADHESIVE BUCCAL DELIVERY FOR PANTOPRAZOLE
... investigate their possible side effects in vivo. An acidic or alkaline formulation will cause irritation of the mucosal membrane and hence this is an important parameter in developing a mucoadhesive dosage form. A combined glass electrode was used for determination of surface pH. The tablets were fi ...
... investigate their possible side effects in vivo. An acidic or alkaline formulation will cause irritation of the mucosal membrane and hence this is an important parameter in developing a mucoadhesive dosage form. A combined glass electrode was used for determination of surface pH. The tablets were fi ...
Maintenance therapy with zuclopenthixol decanoate: associations
... Estonian or Russian origin and they were informed of their rights under the Declaration of Helsinki, as well as of the objectives and risks of the study. The Ethics Review Committee of Clinical Research Studies at the University of Tartu and the ethics committee at Huddinge University Hospital appro ...
... Estonian or Russian origin and they were informed of their rights under the Declaration of Helsinki, as well as of the objectives and risks of the study. The Ethics Review Committee of Clinical Research Studies at the University of Tartu and the ethics committee at Huddinge University Hospital appro ...
ALLEGRA-D - hebust.edu.cn
... Cmax(–46%) and AUC (–42%). Time to maximum concentration (Tmax) was delayed by 50%. The rate or extent of pseudoephedrine absorption was not affected by food. It is recommended that the administration of ALLEGRA-D with food should be avoided. (See DOSAGE AND ADMINISTRATION). Special Populations Spec ...
... Cmax(–46%) and AUC (–42%). Time to maximum concentration (Tmax) was delayed by 50%. The rate or extent of pseudoephedrine absorption was not affected by food. It is recommended that the administration of ALLEGRA-D with food should be avoided. (See DOSAGE AND ADMINISTRATION). Special Populations Spec ...