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Proteomic profiling of non-obese type 2 diabetic skeletal muscle
Proteomic profiling of non-obese type 2 diabetic skeletal muscle

... metabolic disturbances and glucotoxic complications is rapidly increasing worldwide and the incidence of diabetes is approaching endemic proportions (1). Type 2 diabetes mellitus represents a highly complex and heterogeneous disease that is influenced by both genetic and environmental factors (2). A ...
Cardiac muscle
Cardiac muscle

... 2. Explain excitation-contraction (EC) coupling and relaxation in skeletal muscle by identifying the roles of the t-tubules, the calcium channels (Cav1.1 [L-type] and Ryanodine receptor [RyR]), the thin filament regulators (troponin and tropomyosin), and the ATP-dependent SERCA pumps in these proces ...
Muscle cramps! - WordPress.com
Muscle cramps! - WordPress.com

... Muscle cramps occur in the body often during exercise when there is not enough oxygen being delivered to the body, resulting in a build-up of lactic acid. Our body relies on glucose and oxygen to produce ATP (Adenosine triphosphate) through cellular respiration, a complex method of converting nutrie ...
Summary of Metabolism
Summary of Metabolism

... cycle, therefore lactic acid formation occurs • Cori Cycle required ...
Mechanisms of Muscle Strength Gain
Mechanisms of Muscle Strength Gain

... • Long-term  in muscle strength – Associated with significant fiber hypertrophy – Net  protein synthesis takes time to occur – Hypertrophy major factor after first 10 weeks ...
Alternative ways of monosaccharides metabolism
Alternative ways of monosaccharides metabolism

... blood and then into these permeable cells. • Once inside these well-oxygenated cells, lactate can be reverted back to pyruvate and metabolized through the citric acid cycle and oxidative phosphorylation to generate ATP. • The use of lactate in place of glucose by these cells makes more circulating g ...
Lecture 6
Lecture 6

... • Pyruvate kinase (last step of glycolysis): – virtually irreversible in skeletal muscle – In liver, can be inhibited by cAMP and ...
Postexercise recovery of skeletal muscle malonyl-CoA, acetyl
Postexercise recovery of skeletal muscle malonyl-CoA, acetyl

... inhibition of CPT-1 and to allow fatty acids to be oxidized in the postexercise period. It should be emphasized that only those muscle fibers involved in the exercise would exhibit a decrease in malonyl-CoA under these conditions. A previous study (31) indicates that malonyl-CoA does not decrease in ...
Its Up to You KEY - Belle Vernon Area
Its Up to You KEY - Belle Vernon Area

... Perhaps your family and your cultural origins? The processes that occur in all of our bodies that make us human beings. It is the tiny differences—from what’s going on inside to what we experience on the outside that make us truly unique. Tissues are groups of similar cells working together to perfo ...
G.C.S.E - Effects of Exercise
G.C.S.E - Effects of Exercise

... As soon as the body undertakes exercise, the ____________________ start to work harder. Extra energy is required, therefore ____________________ speeds up. This means the level of carbon dioxide in the blood ____________________. The brain detects this and sends signals to your ____________________ ...
Skeletal Muscles
Skeletal Muscles

... muscle fiber is a sarcomere, defined as the distance between two successive Z lines. Within the sarcomere, as the I band becomes shorter, the Z lines approach the ends of the A bands. Structure of Skeletal Muscle Fibers Each skeletal muscle fiber is an elongated cell invested by a delicate membrane ...


... delay the onset of insulin sensitivity, several evidences and studies indicate that exercise may reverse insulin resistance by affecting mitochondrial activity22. Exercise and hormones Estrogen and other hormones production decrease during aging. In addition to its known effect on sexual cycle and a ...
Prelab 3 Circulatory
Prelab 3 Circulatory

... epicardium, but the relative thickness of these layers and the detailed organization of the tissues composing them vary radically in different chambers. (Note the respective continuity of these layers with tunica intima, tunica media, tunica adventitia of blood vessels.) Also, there are highly speci ...
sheet12
sheet12

... 4. They are called Fast fibers because: a. They produce ATP quickly within the cytoplasm by glycolysis, they produce fast contractions 5. The ATPase activity of their myosin's heads is high 6. They are larger than red fibers. 7. They produce fast and strong contraction but for short time. 8. Activat ...
System Responses to Exercise and Disease
System Responses to Exercise and Disease

... Perfusion Dominant effect Perfusion during Exercise (L/min) (L/min) ...
LB Fat metabolism A
LB Fat metabolism A

... Thus, unlike carbohydrates and protein, most lipids do not use the enterohepatic circulatory system. This allows lipids to be cleared by the whole body and avoids overwhelming the liver with lipid. ...
Chiropractic
Chiropractic

... More and more athletes are using chiropractic Chiropractors are an essential member to the evolving athletic triage model Performance enhancement can be achieved by development of the 5 basic biomotor skills Injury prevention is achieved by understanding the correlation between deviations of body me ...
Supplemental Data and Figure
Supplemental Data and Figure

... CaCl2, 0.5 mM EDTA, 5 mM [U-14C]glucose, and 1.2 mM [9,10-3H]palmitate pre-bound to 3% fatty acid free bovine serum albumin (BSA). Hearts were perfused at an 11.5 mmHg left atrial preload and a 60 mmHg aortic afterload. Hearts were perfused for 30 min in the absence of insulin, followed by an additi ...
The Human Body Project
The Human Body Project

... Create a Table outlining different sports and when they may use each system. Give further details regarding how each system may be used during the same sporting activity.(e.g.) Football. Tackling, Shooting, Heading are all quick activities that happen instantaneously during the game. They are fuelle ...
Chapter 2: Human Anatomy
Chapter 2: Human Anatomy

... the red marrow of bone (primarily red blood cells, some white blood cells and platelets). 5. Storage – serves as storage for calcium, phosphorous, potassium, sodium, and other minerals. ...
Ch. 32 - Skin, Bones, & Muscle Powerpoint
Ch. 32 - Skin, Bones, & Muscle Powerpoint

... • Red marrow—found in the humerus, femur, sternum, ribs, vertebrae, and pelvis—is the production site for red blood cells, white blood cells, and cell fragments involved in blood clotting. ...
Immune function in sport and exercise
Immune function in sport and exercise

... depends largely on the type of cytokines that are released by the activated T helper cells. T lymphocytes can be classed as type 1 or type 2 cells, depending on which cytokines they predominantly produce. Type 1 T cells produce mainly IFN-␥ and tumor necrosis factor, and their actions activate macro ...
Ch 5 - KSU Web Home - Kennesaw State University
Ch 5 - KSU Web Home - Kennesaw State University

... supplies oxygen and removes carbon dioxide ...
File - Hills Athletic Academy
File - Hills Athletic Academy

... that low GI foods could be useful in the pre-event meal as they would result in a slower and more sustained release of glucose during exercise maintaining blood glucose levels for a longer period. However, research has been unable to demonstrate that consuming low GI foods prior to exercise has univ ...
PE Revision – Powerpoint of whole specification 2012
PE Revision – Powerpoint of whole specification 2012

... the lactates in the muscles. This will lead to improved performance of the cardiovascular system. •Continuous training develops aerobic fitness. It is training of a lower intensity performed for a longer duration. An example of this would be cycling slowly for thirty minutes. This will increase musc ...
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Myokine

A myokine is one of several hundred cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by muscle cells (myocytes) in response to muscular contractions. They have autocrine, paracrine and/or endocrine effects; their systemic effects occur at picomolar concentrations.Receptors for myokines are found on muscle, fat, liver, pancreas, bone, heart, immune, and brain cells. The location of these receptors explain the fact that myokines have multiple functions. Foremost, they are involved in exercise-associated metabolic changes, as well as in the metabolic changes following training adaptation. They also participate in tissue regeneration and repair, maintenance of healthy bodily functioning, immunomodulation; and cell signaling, expression and differentiation.
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