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Electrophysiology
Electrophysiology

... Whether the action potential travels along an axon by continuous or saltatory conduction, it eventually spreads along telodendria and reaches the axon terminals. ...
Pharmacology—Clinical Uses of Sedatives
Pharmacology—Clinical Uses of Sedatives

... Benzodiazepenes (BDZ) Benzodiazepenes (BDZ) are the most commonly used group of anxiolytics and sedative-hypnotics. Preferred DOC for all types of anxiety disorders. All are controlled substance CIV, but treated like CII in NYS. ALL are pregnancy category D or X. Have various clinical uses. They bin ...
Issues of - AETC-NMC
Issues of - AETC-NMC

... Provide an example of how a polymorphism can affect the response to a drug and why a particular population may be at higher risk for such an effect. ...
Summary Worksheet
Summary Worksheet

... membrane to the sodium ion (Na+). The influx of sodium depolarizes the neurone in a wave from one adjacent area to another, resulting in an action potential. This is how an impulse is carried along a nerve. Inhibitory neurotransmitters have the opposite effect by causing potassium ions (K+) to move ...
4 Depressants
4 Depressants

... The diazepams bind close to the GABA receptor and increase the affinity of GABA for its receptors, which diminishes the excitation of nerves; it also alters rate of peptide formation in neurons, which induces amnesia. This is potentiated by alcohol. ...
Drug development
Drug development

... • Drug interactions • Receptor sensitivity of patient • Mood/personality of patient & doctor • Patients expectations and past experience • Social environment of patient • Clinical state of patient ...
N204
N204

... medications, interactions with healthcare providers, & comply with prescribed med. as well as response physiologically to med. Culturally competent care involves knowledge not only of pt’s beliefs and values about health care and illness, but also of their responses to treatment ...
Behavior Products and Medications
Behavior Products and Medications

commonly used drugs
commonly used drugs

... crystalline form sold in capsules. • Lasts up to 3-6 hours • Taken as a pill but can also be crushed and snorted and/or put into a drink. • Man made (does not come from a plant) • Makers can add whatever they want to it, so the purity and the safety of the drug is always in question • Can become eas ...
Drug Induced Dementia
Drug Induced Dementia

... dementia. • Provide drug examples that can worsen dementia • Describe how to reduce the chance of this happening. ...
SQ109 for the Treatment of Tuberculosis
SQ109 for the Treatment of Tuberculosis

... than   63,000   compounds   with   a   whole-­‐bacterium   high   throughput   Me H screen.1,2   It   is   orally   bioavailable   with   a   distinctive   pharmacological   SQ109 profile3-­‐5   and   has   excellent   activity   against   all   forms ...
Library Of Rare CNS Drugs Available For Collaboration
Library Of Rare CNS Drugs Available For Collaboration

... library   to   ensure   that   each   hit   found   is   actionable.   About   40%   of   the   drugs   are   ex-­‐US   marketed   drugs,  and  the  rest  are  investigational.  55%  of  the  drugs  were  developed  in  the  1980s  and ...
see p. Psy15 - Viktor`s Notes for the Neurosurgery Resident
see p. Psy15 - Viktor`s Notes for the Neurosurgery Resident

... 1. TCAs block NOREPINEPHRINE and SEROTONIN reuptake into presynaptic neuron (→ increased concentrations of monoamines in synaptic cleft); this mechanism is questionable because: – TCA potency in blocking reuptake often does not correlate with clinical antidepressant effect. – reuptake blockade occur ...
A. 4 Variability in drug response a. Define tachyphylaxis
A. 4 Variability in drug response a. Define tachyphylaxis

... Benzodiazepines have increased volume of distribution (if lipid soluble), reduced metabolism and clearance and possibly increased receptor sensitivity. Motor functions may be particularly impaired in the elderly. Narcotics show variable changes in pharmacokinetics. The major concern is that physiolo ...
INTRODUCTION TO PHARMACOLOGY
INTRODUCTION TO PHARMACOLOGY

... decreasing of arterial pressure, stop of breathing Chronic intoxication – cocainism: psychological and physical addiction, mental degradation, cretinism, atrophyc disorders, including perforation of nasal septum, gangrene, heavy cardiac arrythmias, cardiac arrest ...
Guidance regarding Psychoactive Substances
Guidance regarding Psychoactive Substances

... cause unconsciousness, coma and death particularly when mixed with alcohol and/or other downer drugs. On withdrawal feelings of anxiety and if severe withdrawal syndrome develops in heavy drug users, it can require medical treatment. ...
Drug Facilitated Sexual Assault
Drug Facilitated Sexual Assault

... Scenario (cont.) Victim has no memory or only flashes  May recall being awake but unable to move extremities  Perpetrator may tell her that she consented  Victim often too confused or embarrassed to tell anyone or report to police because she can’t remember ...
drugs - TAFE SA Learn
drugs - TAFE SA Learn

... Laboratory - synthetic and semi-synthetic drugs Naturally occurring substances are not safer than those synthesized in laboratories ...
Chapter 14
Chapter 14

...  6th leading cause of death:#prevented, cured, slowed  >/= 65y/o average survival: 4-8 yrs, may up to 20yrs ...
Adverse reactions
Adverse reactions

... serotonin receptors (5-HT), particularly 5-HT2A receptors • The antipsychotics also have variable antagonist actions at muscarinic, α-adrenergic, and histaminergic receptors in brain and peripheral ...
how hiv drugs get approved
how hiv drugs get approved

... There are four phases of human clinical trials. These apply to all drugs, not just drugs for HIV/AIDS. If the results from any phase of testing are not good enough, the company will stop developing the drug. Phase I trials test the safety of new drugs for humans. These trials record the side effects ...
Herb-Drug Interactions
Herb-Drug Interactions

... • Decreased bioavailability digoxin and cyclosporin when S.J.W. is consumed • Induction of mania in depressed patients with neoleptic drugs; are taken with betel nut (Areca sp.) • Increased risk of hypertension when tricyclic antidepressants are combined with yohimbine • High soluble fiber plants su ...
Antidepressant
Antidepressant

... implicate monoamines in the aetiology of the illness at all • treatments from different antidepressant classes appear to have the common property of increasing the expression of neuroprotective proteins, important in the function and growth of neurons ...
Document
Document

... Considerations for taking prescription drugs: Most common problem – Ask how to Nontake medication adherence Take entire course Physical and psychological side Side effects are possible Effects Review information on side effects OTC and prescription drugs interact with each other Drug Interactions Al ...
Toxicology Power Point
Toxicology Power Point

... • Symptoms, therefore, include increased heart rate, dilated pupils, and difficulty breathing ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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