Psychoactive Drugs
... Considered safer than Barbiturates; prescribed much more often Examples Valium Xanax Librium Minor tranquilizers can STILL be very addictive & dangerous ...
... Considered safer than Barbiturates; prescribed much more often Examples Valium Xanax Librium Minor tranquilizers can STILL be very addictive & dangerous ...
Effects and Sites of Action of Different Agonists Drugs (Stimulant or
... - To determine ( analyze) the activity of drug (i.e. analgesic, hypotensive and hypoglycemic). -To determine mechanism of drugs action. ...
... - To determine ( analyze) the activity of drug (i.e. analgesic, hypotensive and hypoglycemic). -To determine mechanism of drugs action. ...
FACTORS MODIFYING DRUG EFFECTS
... there occurs change in responsiveness caused by increase or decrease in number of receptor sites or alteration in efficiency of coupling of receptor to ...
... there occurs change in responsiveness caused by increase or decrease in number of receptor sites or alteration in efficiency of coupling of receptor to ...
Anti-Parkinsonism drugs
... young patients ; they decrease tremor and rigidity but have little effect on hypokinesia . They are first choice drugs for treatment of drug-induced parkinsonism S.Es: some peripheral antimuscarinic side effects : dry mouth, difficult urination, blurred vision In overdose , they can cause acute conf ...
... young patients ; they decrease tremor and rigidity but have little effect on hypokinesia . They are first choice drugs for treatment of drug-induced parkinsonism S.Es: some peripheral antimuscarinic side effects : dry mouth, difficult urination, blurred vision In overdose , they can cause acute conf ...
Adrenergic Agonists
... 1. Synthesis of norepinephrine: 1. Tyrosine is transported by a Na+-linked carrier into the axoplasm of the adrenergic neuron 2. Tyrosine is hydroxylated to dihydroxyphenylalanine (DOPA) by tyrosine hydroxylase. 3. DOPA is then decarboxylated by the enzyme dopa decarboxylase (aromatic l-amino acid ...
... 1. Synthesis of norepinephrine: 1. Tyrosine is transported by a Na+-linked carrier into the axoplasm of the adrenergic neuron 2. Tyrosine is hydroxylated to dihydroxyphenylalanine (DOPA) by tyrosine hydroxylase. 3. DOPA is then decarboxylated by the enzyme dopa decarboxylase (aromatic l-amino acid ...
MIGRAINE
... Metabolized in liver to active metabolites which have a higher affinity to 5HT1B & 1D receptors than the parent drug. Half- life for both 2-3hrs. Plasma protein binding 14%. ...
... Metabolized in liver to active metabolites which have a higher affinity to 5HT1B & 1D receptors than the parent drug. Half- life for both 2-3hrs. Plasma protein binding 14%. ...
Alzheimer`s Disease
... – structures previously described in the brains of elderly people – neuritic or senile plaques – structures contained within brain cells that had not been previously observed – neurofibrillary tangles. ...
... – structures previously described in the brains of elderly people – neuritic or senile plaques – structures contained within brain cells that had not been previously observed – neurofibrillary tangles. ...
Citalopram Hydrobromide - McGraw-Hill
... Drug-herb. St. John’s wort, S-adenosylmethionine (SAM-e): increased risk of serotonergic reactions, including serotonin syndrome Drug-behaviors. Alcohol use: additive CNS depression Sun exposure: photosensitivity Reactions in bold are life-threatening ...
... Drug-herb. St. John’s wort, S-adenosylmethionine (SAM-e): increased risk of serotonergic reactions, including serotonin syndrome Drug-behaviors. Alcohol use: additive CNS depression Sun exposure: photosensitivity Reactions in bold are life-threatening ...
(HL): Drug Design
... However, this was bitter tasting and still irritating to the stomach lining. So aspirin was developed by creating an ester to make it less acidic, and therefore less irritating. It is also tasteless. However, this form is also insoluble in water. So the salt of acetylsalicylic acid can also be p ...
... However, this was bitter tasting and still irritating to the stomach lining. So aspirin was developed by creating an ester to make it less acidic, and therefore less irritating. It is also tasteless. However, this form is also insoluble in water. So the salt of acetylsalicylic acid can also be p ...
NeuTropic™ Products - Biotics Research Corporation
... considered to be immunoregulatory in nature. Low levels or imbalances of dopamine have been associated with depressed mood, addiction, inability to concentrate, hyperactivity and/or lethargy, and muscle stiffness. Through its effects on the neurotransmitter dopamine, Mucuna may have a positive effec ...
... considered to be immunoregulatory in nature. Low levels or imbalances of dopamine have been associated with depressed mood, addiction, inability to concentrate, hyperactivity and/or lethargy, and muscle stiffness. Through its effects on the neurotransmitter dopamine, Mucuna may have a positive effec ...
Diabetes Therapy and Problems for the Cardiologist. Quali
... mechanism of action • bind to and activate peroxisome proliferatoractivated receptors (PPARs), which regulate gene expression in response to ligand binding • increase insulin sensitivity by acting on adipose, muscle, and liver to increase glucose utilization and decrease glucose production • drugs i ...
... mechanism of action • bind to and activate peroxisome proliferatoractivated receptors (PPARs), which regulate gene expression in response to ligand binding • increase insulin sensitivity by acting on adipose, muscle, and liver to increase glucose utilization and decrease glucose production • drugs i ...
Kineta`s Novel Antiviral Drugs Show Encouraging
... New data presented at International Conference on Antiviral Research SEATTLE, WA, May 19, 2014--Kineta, Inc. a biotechnology company focused on the development of immune modulating drugs for critical disease areas, announced today that its scientists reported encouraging new data from its innate- im ...
... New data presented at International Conference on Antiviral Research SEATTLE, WA, May 19, 2014--Kineta, Inc. a biotechnology company focused on the development of immune modulating drugs for critical disease areas, announced today that its scientists reported encouraging new data from its innate- im ...
Slide 1
... Sulfate conjugation is the major metabolic process in the elimination of -agonists More side effects of palpitation & tremor Grapefruit and Orange juices also suppress SULT1A3 but not as strong as tea ...
... Sulfate conjugation is the major metabolic process in the elimination of -agonists More side effects of palpitation & tremor Grapefruit and Orange juices also suppress SULT1A3 but not as strong as tea ...
exam model-ii
... The term that describes what a drug does to body and particularly its mechanism of action is called: A. Pharmacodynamics. B. Pharmacokinetics. C. Efficacy. D. None of the above. ...
... The term that describes what a drug does to body and particularly its mechanism of action is called: A. Pharmacodynamics. B. Pharmacokinetics. C. Efficacy. D. None of the above. ...
Lecture 9 - Abercrombie 10/27 Notes
... conducive to penetration and compounds will distribute throughout body. Penetration of drugs into CNS is a special case. BLOOD-BRAIN-BARRIER: Rate of penetration of water-soluble and ionized compounds into CNS relatively slow compared with rate of distribution into peripheral tissue. Lipid soluble d ...
... conducive to penetration and compounds will distribute throughout body. Penetration of drugs into CNS is a special case. BLOOD-BRAIN-BARRIER: Rate of penetration of water-soluble and ionized compounds into CNS relatively slow compared with rate of distribution into peripheral tissue. Lipid soluble d ...
Company Core Data Sheets (CCDS)
... than that for D2 receptors, an interaction between QUINAGOLIDE and 5-HT1a receptors is unlikely. However, care should be taken with concomitant use of medication interfering with these receptors. Due to limited data available with respect to the enzyme(s) involved in the metabolism of quinagolide, p ...
... than that for D2 receptors, an interaction between QUINAGOLIDE and 5-HT1a receptors is unlikely. However, care should be taken with concomitant use of medication interfering with these receptors. Due to limited data available with respect to the enzyme(s) involved in the metabolism of quinagolide, p ...
Lecture 10 Wednesday, October 27, 2010 1:03 PM Physiology of
... An inflammatory mediator Found in both peripheral and central nervous system Central Sensitization Secondary hyperalgesia and/or allodynia Dorsal horn of the spinal cord Enhanced response to the same stimuli following repetitive, high intensity sitmulation Primary neurons fire repeatedly ...
... An inflammatory mediator Found in both peripheral and central nervous system Central Sensitization Secondary hyperalgesia and/or allodynia Dorsal horn of the spinal cord Enhanced response to the same stimuli following repetitive, high intensity sitmulation Primary neurons fire repeatedly ...
carbidopa-levodopa - McGraw
... MEDICATION: carbidopa-levodopa (Brand names include Sinemet and Sinemet CR.) WHAT IT'S USED FOR: Carbidopa-levodopa is used to treat Parkinson’s disease. HOW TO TAKE IT If you're using the long-acting form of this drug, take it with food to increase its effects. Don’t crush or chew the long-acting f ...
... MEDICATION: carbidopa-levodopa (Brand names include Sinemet and Sinemet CR.) WHAT IT'S USED FOR: Carbidopa-levodopa is used to treat Parkinson’s disease. HOW TO TAKE IT If you're using the long-acting form of this drug, take it with food to increase its effects. Don’t crush or chew the long-acting f ...
Document
... 36. Sulphamethoxazole is combined with trimethoprim in cotrimoxazole because the two drugs: a. Have matching volumes of distribution b. Have similar plasma protein binding c. Have matching half lives d. Inhibit different steps in a metabolic pathway in the organisms e. Are excreted through the same ...
... 36. Sulphamethoxazole is combined with trimethoprim in cotrimoxazole because the two drugs: a. Have matching volumes of distribution b. Have similar plasma protein binding c. Have matching half lives d. Inhibit different steps in a metabolic pathway in the organisms e. Are excreted through the same ...
Antidepressant_agents
... serotonergic neurotransmission by blocking the central alpha autoreceptors and heteroreceptors, a potent antagonist, rapidly absorbed orally ...
... serotonergic neurotransmission by blocking the central alpha autoreceptors and heteroreceptors, a potent antagonist, rapidly absorbed orally ...
Drugs ppt
... • P. 257in paper text heroin under scope, b image with mercuric iodine most useful • Also, infrared tests and spectrophotometry can identify substance ...
... • P. 257in paper text heroin under scope, b image with mercuric iodine most useful • Also, infrared tests and spectrophotometry can identify substance ...
Body Mass Index and Alcohol Use - Obesity and Food Addiction
... PET and 2-deoxy-2[18F]fluro-D-glucose have also been used in human subjects to assess whether or not obese subjects have an enhanced sensitivity in the brain region associated with sensory processing of food.53 It was found that, in fact, obese subjects did have significantly greater glucose metabol ...
... PET and 2-deoxy-2[18F]fluro-D-glucose have also been used in human subjects to assess whether or not obese subjects have an enhanced sensitivity in the brain region associated with sensory processing of food.53 It was found that, in fact, obese subjects did have significantly greater glucose metabol ...