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Prevention Guide - Safe Handling of Hazardous Drugs
Prevention Guide - Safe Handling of Hazardous Drugs

... NOTE: The information contained in this document is not exhaustive and in no way represents a legal interpretation of the laws and regulations. Your sectorbased association, the ASSTSAS, in no way guarantees that occupational accidents or diseases and the hazards related thereto will be eliminated t ...
ppt - Home
ppt - Home

... +  K intake serum K+ despite vomiting Hypochloremia gastric chloride losses Hyponatremia free water retention due to volume contraction ...
Citizen Petition to Investigate Polyethylene Glycol 3350
Citizen Petition to Investigate Polyethylene Glycol 3350

... name PEG-3350. PEG-3350 products exist in a stable powder form. Approved products instruct patients to dissolve the PEG-3350 powder in a liquid and use immediately. The approved products have been tested under these conditions and are stable. It is unknown if prolonged duration in solution would cha ...
The FDA’s Continuing Incapacity on Livestock Antibiotics *
The FDA’s Continuing Incapacity on Livestock Antibiotics *

... explain here, however, the initiatives leave much to be desired, for four basic reasons. First, the success of the FDA’s policy on “judicious use” depends on multiple layers of voluntary action by profit-maximizing drug companies. Although early indications of drug companies’ cooperation are promisi ...
A New Look at the 5α-Reductase Inhibitor Finasteride
A New Look at the 5α-Reductase Inhibitor Finasteride

... After the initial demonstration that the synthetic steroid alphaxalone potentiated GABAgated chloride currents (67), strong evidence indicated that steroid metabolites have rapid membrane actions via an interaction with ligand-gated ion channels (8,13,93,102,123). Based on this evidence and consensu ...
Zidovudine Concentration in Brain Extracellular Fluid Measured by
Zidovudine Concentration in Brain Extracellular Fluid Measured by

... rate, physicochemical properties of the drug, and tissue factors determine recovery (Bungay et al., 1990; Stenken, 1999). Larger microdialysis membrane surface provides greater area for diffusion and enhanced recovery. The molecular weight cutoff (MWCO), composition, and surface charge of the dialys ...
Prescribing Information
Prescribing Information

... In an active-controlled clinical study in patients receiving HEC, safety was evaluated for 1143 patients receiving a single dose of EMEND for injection compared to 1169 patients receiving the 3-day regimen of oral EMEND (aprepitant) [see Clinical Studies (14.1)]. The safety profile was generally sim ...
introduction - KSU Faculty Member websites
introduction - KSU Faculty Member websites

... laboratory animals. So the purpose of this study is to investigate the interactions between MCP and CPX, given in single i.v. doses, on electrocardiographic parameters in anesthetized rats during 90-min duration, with special concern to the QT interval prolongation and torsadogenic potential. Moreov ...
Meperidine - Home - KSU Faculty Member websites
Meperidine - Home - KSU Faculty Member websites

... Effects of meperidine: • The effects of meperidine are felt 10-15 minutes after ingestion and typically last anywhere from 2-4 hours. • mepiridine effects are very similar to morphine, with sedation, respiratory depression and euphoria less intense than that of morphine. • nausea and vomiting are c ...
Ganja and Geriatrics: The Health Benefits and Risks of Medicinal
Ganja and Geriatrics: The Health Benefits and Risks of Medicinal

... As the United States population grays, it faces a myriad of controversial issues regarding older adults. One such issue is the use of various types of alternative medication, specifically the use of marijuana as a treatment for a variety of ailments. It is important to explore all possible routes on ...
CHAPTER 1 The Nursing Process and Drug Therapy
CHAPTER 1 The Nursing Process and Drug Therapy

... The metabolism of a drug and its passage from the liver into the circulation – A drug given via the oral route may be extensively metabolized by the liver before reaching the systemic circulation (high first-pass effect) – The same drug—given IV—bypasses the liver, preventing the first-pass effect f ...
Evaluation of Diuretic activities of hydro
Evaluation of Diuretic activities of hydro

... body salt and fluid balance and blood pressure homeostasis through the actions of their nephrons (Zhuo and Li, 2013). Nephrons are the structural and functional units of the kidneys. Each kidney contains over one million of these tiny blood processing units, which carry out the processes that form u ...
PDF
PDF

... (e.g. primaquine) prevent onwards transmission from the treated individual to the mosquito population, but this means that there might be a delay before any effect is seen in terms of transmission from mosquitoto-human. However, ivermectin’s mosquito lethal and sublethal effects can quickly suppress ...
alcohol consumption habits and sleep quality
alcohol consumption habits and sleep quality

... damage, damage to the peripheral nervous system, reduced potency of eye, toxic damage to the lungs and kidneys, the development of fetal alcohol syndrome, and there is a general physical deterioration (4). Sleep is brain activity that is defined as a state of unconsciousness from which a person can ...
Determination of Atorvastatin Pharmacokinetic
Determination of Atorvastatin Pharmacokinetic

... other drugs, food, beverages or dietary supplements on its effect and activity [8-10]. Recently, many research groups illustrated the alterations in metabolism of many drugs by known popular juices like grapefruit, orange, and pomegranate juices [10-15]. Generally, drug – food interactions and in pa ...
research
research

... mean arterial pressure were also taken. Finally, participants completed visual analogue scales assessing their subjective mood state. Results The majority of cognitive tasks showed dose-dependent declines in performance. Mean arterial pressure was significantly reduced, as was pulse rate. Subjective ...
Product Monograph
Product Monograph

... Consequently, patients should be cautioned against driving a car or operating hazardous machinery until they are reasonably certain that Celexa® does not affect them adversely. Bone Fracture Risk Epidemiological studies show an increased risk of bone fractures following exposure to some antidepressa ...
How do you switch between tricyclic, SSRI and related
How do you switch between tricyclic, SSRI and related

... option if the first antidepressant has been taken for less than six weeks or if severe side effects with the first antidepressant have occurred. If this regimen is chosen, a low starting dose of the second SSRI should be used and titrated up. This method has also been suggested for switching from SS ...
Congenital disorders of autophagy: an emerging
Congenital disorders of autophagy: an emerging

... autophagy genes map to different stages of this highly conserved pathway and thus lead to impairment in isolation membrane (or phagophore) and autophagosome formation, maturation, or autophagosome-lysosome fusion. Here we discuss ‘congenital disorders of autophagy’ as an emerging subclass of inborn ...
A SURVEY BASED STUDY IN CURRENT SCENARIO OF GENERIC AND... Research Article
A SURVEY BASED STUDY IN CURRENT SCENARIO OF GENERIC AND... Research Article

... same active ingredients and are shown to work the same way in the body, they have the same risks and benefits as their brand name counterparts. Also, generic drugs have the same quality, strength, purity and stability as brand name drugs. It is seen that Generic Drugs work in the same way and in the ...
Dow Corning Silicones in Pharmaceutical Applications
Dow Corning Silicones in Pharmaceutical Applications

... also appeared recently on the market; yet if this eases the handling prior to use (no mixing), these 1-part materials have a very limited shelf life. Some precautions are required with this addition reaction as platinum catalysts can be poisoned by many nucleophilic substances possibly present as co ...
Reviewing the reality: why we need to change * Peter J. Lin Introduction
Reviewing the reality: why we need to change * Peter J. Lin Introduction

... The limitations associated with warfarin therapy have resulted in the global problem of under-treatment with anticoagulants for the prevention of strokes in AF. In Italy, for example, only about one in five hospitalized patients with AF will receive oral anticoagulation and only 25% of chronic AF pat ...
Lithium Key Points Introduction in General Practice
Lithium Key Points Introduction in General Practice

... drug concentrations reducing therapeutic response or ...
Switching between tricyclic, SSRI and related antidepressants
Switching between tricyclic, SSRI and related antidepressants

... option if the first antidepressant has been taken for less than six weeks or if severe side effects with the first antidepressant have occurred. If this regimen is chosen, a low starting dose of the second SSRI should be used and titrated up. This method has also been suggested for switching from SS ...
Changes in the mitochondrial electron transport chain (ETC
Changes in the mitochondrial electron transport chain (ETC

... continues to fall (4). Although, LSD is not considered as an addictive drug since it does not produce compulsive drug-seeking behavior and most users of LSD voluntarily decrease or stop its use over time, LSD does produce a physiologic tolerance requiring subsequent increased doses for the same effe ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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