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Brain tumour research (Dept of Neurosurgery RPH and BTNW)
Brain tumour research (Dept of Neurosurgery RPH and BTNW)

... growth suppressive effects of Mifepristone on glioma cell lines. We were however not able to demonstrate growth stimulation by either Progesterone or Dexamethasone to any significant degree. Also, we found that effect of Mifepristone was most pronounced on days 3 and 4 rather than from day 2. None o ...
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STUDY OF THE ROLE OF THE BED NUCLEUS OF

... model to provide explanatory power and to assess how various variables influence the development of addiction. Predictive validity refers to the model’s ability to produce valid predictions about the human form of addiction based on results from the animal model (Koob and Le Moal, 2006). Another rea ...
KROK 2 Pharmacy
KROK 2 Pharmacy

... 21. Drug users after the expiration of a drug actions having severe mental, neurological and somatic disorders. What is the name of this symptom? A. *Abstinent syndrome B. Tachyphylaxis C. Sensibilization D. Accumulation E. Tolerance 22. A patient came to the pharmacy, the patient, who for 3 months ...
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Week 6- Bioavailability and Bioequivalence
Week 6- Bioavailability and Bioequivalence

... For drug products that are not intended to be absorbed into the bloodstream, bioavailability may be assessed by measurements intended to reflect the rate and extent to which the active ingredient or active moiety becomes available at the site of action. ...
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Drug Products That Have Been Withdrawn from the US Market
Drug Products That Have Been Withdrawn from the US Market

... Drug Products That Have Been Withdrawn from the U.S. Market Since 2000, the U.S. Food and Drug Administration has approved nearly 300 new drug applications and biologics license applications for new molecular entities. In the same time period, a few new drugs were withdrawn from the market by the ma ...
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Ecstasy - a quick guide to drugs and alcohol

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DOXAZOSIN MESYLATE - The Filipino Doctor

... Dosage and Method of Administration The usual maintenance dose is 4 mg daily; daily doses of 8 mg should not be exceeded. The optimal effect of doxazosin may take up to 4 weeks. If necessary, the dosage may be increased following this period to 8 mg once daily according to patient response. Doxazosi ...
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Implications of Immunogenicity in Drug Development

... quantitation assays this includes the presence of ADA; ADA assays are similarly prone to interference from free drug. Antibody drugs in particular have long half-lives, and ADA may stabilize drugs thereby prolonging the half-life. Effort is made to minimize these interferences as much as possible: t ...
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... 1. The vial must be a single use vial. Multi-use vials are not subject to payment for any discarded amounts of the drug. 2. The units billed must correspond with the smallest dose (vial) available for purchase from the manufacturer(s) that could provide the appropriate dose for the patient. For exam ...
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Docusate Sodium and Pregnancy
Docusate Sodium and Pregnancy

... I just found out I am pregnant. Should I stop taking docusate sodium? You should always talk with your health care provider before making any changes in your medication. It is important to consider the benefits of treating constipation symptoms during pregnancy. Your health care provider may also wa ...
Medical Marijuana in the Workplace
Medical Marijuana in the Workplace

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Using proton-pump inhibitors among haemodialysis patients

... substantial number of patients administer the drug in a wrong time or manner - occasional use. Some patients took PPIs at night, in contrast to recommendation of a once-daily morning dosage [25] prior to a meal [26]. Furthermore, many of them were not aware of this importance. PPI failure is a frequ ...
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... DH: It must have been very noisy, smelly and dirty on the wards in those years. KR: Yes, in the beginning. Still, I decided to enter psychiatry and get a good training. So, I contacted a few places on the East Coast and the University of Pennsylvania asked me to visit but I didn’t have enough money ...
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Limitations of Antiretroviral Therapy

...  Review potential side effects  Anticipate and treat side effects  Utilize educational aids including pictures, pillboxes, and calendars  Individualized adherence programs ...
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... • Conversely, the inability to detect drug-specific IgE antibodies does not R/O the possibility of sensitivity. • Desensitization protocols are indicated in established cases of drug hypersensitivity where there is NO substitute and treatment is essential (e.g. penicillin for ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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