Download KROK 2 Pharmacy

KROK 2 Pharmacy
PHARMACOLOGY
2
For what purpose acetylsalicylic acid was appointed to the patient with angina pectoris?
A * antiplatelet action
B inhibition of fibrinolytic activity of blood
C agregant action
D anti-inflammatory action
E increase fibrinolytic activity of blood
3
Patient 32 years takes antituberculosis drugs. Some time later he noticed that urine acquired redorange color. What drug contributed to the emergence of this phenomenon?
A * Rifampicin
B Isoniazid
C Pirazinamide
D Ethambutol
E Streptomycin
4
Neuroleptic analgesia was conducted in the patient with myocardial infarction. What drug from
the group of neuroleptics often used together with fentanyl?
A * Droperidol
B Aethaperazinum
C Levomepromazin
D Clozapine
E Sulpiride
5
Gastric bleeding due to ulceration of the gastric mucosa was occurred in the patient 55 years on
the 4th day of treatment with indomethacin. What is the reason of ulcerogenic effect of the drug?
A* Increase activity of COX-1
B Increase activity of COX-2
C Increase activity of lipoxygenase (LOG)
D Increase activity of thromboxane synthetase
E Increase activity of prostacyclin synthetase
6
The patient 45 years with thrombophlebitis takes Neodicumarinum (Ethyl biscoumacetate)
during 2 weeks. At the next examination a reduction in blood prothrombin was found and
microscopic hematuria was observed in urine. Which drug you want to apply as an antagonist of
Neodicumarinum?
A * Vicasol (menadione)
B Protamine sulfate
C Sodium citrate
D Heparin
E Aminocaproic acid
7
In the emergency department the patient with complaints of shortness of breath, excessive
salivation, abdominal cramps, diarrhea, dizziness, blurred vision was taken. It has been
diagnosed: organophosphate poisoning. Select drugs that appropriate to include in the pathogenic
therapy?
A * Atropine and dipiroximum
B Sodium thiosulfate and bemegridum
C Tetacinum-calcium and Unithiol
D nalorphine and bemegridum
E Glucose and bemegridum
8
In the emergency department patient is delivered with complaints of dry mouth, blurred vision
and photophobia. On examination it was established that flushed and dry skin, dilated pupils,
tachycardia. It was diagnosed as belladonna alkaloids poisoning. What the drug is appropriate to
apply?
A * Proserin
B Aceclidine
C Pilokarpine hydrochloride
D Arminum
E Dipiroximum
9
A patient with hypertension crisis was injected Clophelinum (Clonidine). Which mechanism lies
at the base of its antihypertensive action?
A. *The stimulation of presynaptic alpha-2-adrenoceptors
B. Blockade of peripherial alpha-1-adrenoceptors
C. Blockade of beta-adrenoceptors
D. Blocksde of N-cholinoceptors of the vegetative ganglia
E. Direct myotropic action on vessels
10. Patient with ulcer disease Ranitidin was prescribed. The stomach acidity was significantly
reduced. Which mechanism lies at the base of this preparation's action?
A. *Blockade of H2-histaminoreceptors
B. Blockade of H1-histaminoreceptors
C. Blockade of M-cholinoreceptors
D. Reduction in H+/K+ ATPase activity
E. Blockade of N-cholinoreceptors of visceral ganglia
11. A patient with heart glycoside intoxication symptoms was prescribed Unithiol. What is the
healing mechanism of this preparation?
A. *Reactivation membraneus H+/K+ ATP-ase
B. Binding of ionised Ca2+
C. Increase K+ heart muscles
D. Increase the amount of Na+ in the myocardium
E. Induction of heart glycosides metabolism
12. To remove delirium and hallucinations in a woman with schizophrenia, the doctor used
Aminazinum. What is the mechanism of its action?
A. *Inhibition of the dopaminergic processes in CNS
B. Stimulates the adrenergic and dopaminergic processes in the CNS
C. Stimulates the cholinergic processes in the CNS
D. Inhibition of the cholinergic processes in the CNS
E. Inhibition of the adrenergic processes in the CNS
13. A 52 year old man was diagnosed systemic amebiasis with the damage of intestines, liver
and lungs. Which preparation should be prescribed?
A.* Metronidazolum
B. Chiniofon
C. Tetracyclinum
D. Chingaminum
E. Phthalazolum
14. As a result of myocardium infarction a ventricular arrhythmia has developed in the patient.
His heart rate was brought back to normal after receiving an antiarrhythmic drug with local
anesthetic activity. Which preparation was used?
A. *Lidocainum
B. Novocainum
C. Verapamilum
D. Pananginum
E. Propranololum
15. A 38 year old patient was delivered to the emergency department in serious condition It was
mercury poisoning. Which antidote should be immediately given to the patient?
A. *Unithiol
B. Dipiroximum
C. Atropine
D. Nalorphine
E. Izonitrozinum
16. A 33 year old woman with chronic polyarthritis and a long time treated for chronic
polyarthritis, and complains of increased blood pressure, changes in the distribution of adipose
tissue, menstrual disorders. What drug the patient takes?
A. *Prednisolonum
B. Indometacinum
C. Butadionum
D. Sinaflanum (Fluocinolone acetonide)
E. Diclofenac sodium
17. A pregnant woman (20 weeks) has caught pneumonia. Which chemotherapy preparation can
be recommended without threat to fetal development?
A. *Benzylpennicilin
B. Gentamicinum
C. Sulfalenum
D. Levomicetinum
E. Ofloxacinum
18. During a surgical operation, as a muscle relaxant Tubocurarine choride was used. Which
antagonist preparation should be given to the patient to restore his self-breathing?
A. *Proserinum
B. Dithylinum
C. Cytitonum
D. Aethimizolum
E. Веnzohexonium
19.A patient with allergic dermatitis Suprastine was prescribed. Which group antiallergic drugs
belongs this drug?
A. *H1 histamine receptor blocker
B. Glucocorticosteroids
C. Inhibitors of mast cell degranulation
D. Leukotriene receptor antagonists
E. H2 histamine blockers
20. A child accidentally drank a solution from a bottle which contains grandma's glaucoma
treatment drug. It appeared that it was pilocarpine hydrochloride. Which preparation could be
used as the antidote?
A. *Atropine
B. Carbacholinum
C. Aceclidine
D. Benzohexonium
E. Pentaminum
21. Drug users after the expiration of a drug actions having severe mental, neurological and
somatic disorders. What is the name of this symptom?
A. *Abstinent syndrome
B. Tachyphylaxis
C. Sensibilization
D. Accumulation
E. Tolerance
22. A patient came to the pharmacy, the patient, who for 3 months took phenazepam. The patient
insisted on buying two more packs of the drug, explaining that he doesn't feel well without it.
What lies at the base of this side effect?
A. *Drug addiction
B. Idiosyncrasy
C. aftereffect syndrome
D. Accumulation
E. Tolerance
23 A patient with allergic rhinitis was prescribed ephedrine in nose drops form. Using this
preparation, significantly improves the patient's state which made him use it every 2 hours, but
the effect wasn't present. What lies at the base of ephedrine's inefficiency?
A. *Tachyphylaxis
B. Drug addiction
C. Idiosyncrasy
D. Allergy
E. Accumulation
24 A patient with hypertensive crisis during complex treatment needs to be prescribed diuretics.
Advise the doctor-intern, which preparation should be used?
A.* Furosemidum
B.Diacarbum
C.Spironolactonum
D.Triamterenum
E. Amiloridum
25 Which antiprotozoal agent can be recommended to a woman, who suffering trichomoniasis?
A.* Metronidazolum
B.Primachinum
C.Chloridinum
D.Solusurminum
E.Chiniofonum
26 Choose an antiseptic from the Halogenic group, which can be put in a child's first-aid kit, for
the child who is going to summer camp?
A.* Iodine spirit solution
B.Brilliant green
C.Cuprum sulfate
D.Methylene blue
E. Formaldehyde solution
27 A drug of a new generation of non-steroid anti-inflammatory drugs came to the pharmacy.
Its name is "meloxicam". What are its advantages as a COX-2 blocker in comparison with other
non-steroid anti-inflammatory preparations?
A. * Minimum side effects on the digestive tract
B.Significant antispasmodic effect
C.Interferonogenic properties
D.Minimum hemotoxic effects
E. Significant inhibition of protease’s activity
28 In the absence of Fenoterol in the inhalator form in the pharmacy, which preparation from
the bronchoselective beta-2-adrenomimetics can be used to replace it?
A.* Salbutamolum
B.Isadrinum
C.Metacinum
D.Ephedrinum
E. Euphyllinum
29 Answer the internist's question: which modern antihistamine preparation is the best for
people who's work demands quick reactions?
A. * Loratadinum
B.Dimedrolum
C.Diprasinum
D.Suprastinum
E. Pipolphen
30 A patient has come to the doctor with complaints of loosing night sight and dry cornea.
What preparation was prescribed by the doctor?
A.*Retinol
B.Pyridoxine
C.Tocopherol
D.Ascorbinic acid
E. Cocarboxylase
31 A patient with hypertonic disease has a high level of renin in the blood plasma. Which
pharmacological group should be given privilege over the others?
A.*ACE-inhibitors
B.Alfa-adrenoblockers
C.Diuretics
D.Ca2+ ions antagonists
E. Sympatolytics
32 A patient with stomach ulcer disease Almagel was prescribed. Which pharamcological
property of the drug is used to treat this pathology?
A.* HCl neutralisation
B.Local anesthetic activity
C.Blockade of H2-histamine receptors
D.Blockade of M-histamine receptors
E. Anti-inflammatory activity
33 After a long usage of phenobarbital, a patient with epilepsy has developed a tolerance to the
preparation. What lies at the base of this action?
A.* Acceleration of biotransformation
B.Weakening of drug absorbtion
C.Increasing of receptors sensitivity
D.Weakening of biotransformation
E. Accumulation of the drug in the organism
34 The doctor prescribed a preparation from the tricyclic antidepressants group for a patient
with depression. Name the preparation.
A.*Amitriptylinum
B. Phenazepam
C. Droperidol
D.Aminalonum
E. Caffeine
35 A patient with hypertonic disease has consulted a doctor about complains of dry cough,
which appeared as a result of treatment. Which hypotensive preparation did she use?
A.* Lisinopril
B.Atenolol
C.Nifedipin
D.Furosemidum
E. Dichlothiasidum
36 A patient with ulcer disease was prescribed Famotidine. Explain which mechanism is in the
base of its action?
A.*Blockade of H2-histaminoreceptors
B.Blockade of H1-histaminoreceptors
C.Blockade of M-cholinoreceptors
D.Inhibition of Н+К+АТP-ase activity
E. Blockade of cholinoreceptors of sympathetic ganglions
37 Explain, what does the medical term period of half-excretion (Т1/2) mean?
A.*The time required to decrease the drug concentration in the blood by one-half (reduced by
50%)
B.The plasma volume which is relieved from the drug per unit time
C.The time of total elimination of the drug from the organism
D.The speed of renal excretion of the drug
E. The ratio of the speed of excretion of the drug and its plasma concentration
38 Reduction in the absorbtion of tetracycline preparation group at their simultaneous usage
with antacids is an example of:
A. * Pharmacokinetic incompatibility
B.Pharmaceutic incompatibility
C.Pharmacodynamic incompatibility
D.Sinergism of drugs
E. Functional antagonism of the drugs
39 Give an answer to a visitor of your pharmacy what side effect is specific for Captopril?
A. * Dry cough
B.Hypertension
C.Hyperglycemia
D.Disturbances of cardiac rhythm
E. Hypokaliemia
40 Consult, which antihistamine preparation does not have a soporific and sedative action?
A.*Loratadinum
B.Dimedrolum
C.Diprasinum
D.Suprastinum
E. Tavegil
41 Help the doctor choose the preparation for replacement therapy after the extraction of the
thyroid gland.
A.*L-thyroxinum
B.Insulinum
C.Prednisolonum
D.Parathyreoidinum
E. Mercasolilum
42 Treating hypertonic disease, a doctor has prescribed a preparation which blocks angiotensin
receptors. Name it.
A.*Losartan
B.Nifedipin
C.Prazosin
D.Captopril
E. Apressinum
43 A patient with ulcer disease was prescribed Omeprazole. What is the mechanism of action of
this drug?
A.*Inhibition of Н+К+-АТP-ase
B.Blockade of histaminic H2-receptors
C.Blockade of M-cholinoreceptors
D.Neutralisation of HCl
E. Stimulation of mucous secretion
44 Which anticeptic provides bactericidal action by the formation of atomic Oxygen?
A.*Kalii permanganas
B.Chloraminum
C.Furacilinum
D.Etonium
E. Silver nitrate
45 A patient with dyskinesia of the digestive tract was prescribed Metoclopramide. What is the
antiemetic action of this preparation related with?
A.*Blockade of D2-receptors
B.Blockade of M1-cholinoreceptors
C.Blockade of H1-cholinoreceptors
D.Stimulation of beta-adrenoreceptors
E. Stimulation of M1-cholinoreceptors
46 While treating chronic heart failure with digitoxinum, the patient started showing signs of
intoxication. The doctor prescribed Unithyol. Explain the action of Unitiol during heart
glycosides intoxication.
A.*Restoration of К+-Na+АTP-ase activity
B.Binding of Ca2+ions
C.Increasing of Na+ level in cardiomyocytes
D.Increasing of permeability of cardiomyocytes for K+
E. Binding of glycoside into the non-active complex
47 The part of an administered dose of unchanged drug that reaches the systemic circulation is
called:
A.*Bioavaliability
B.Period of half-adsorbtion
C.Period of half-excterion
D.Volume of distribution
E. Period of half-elimination
48 A 67 year old patient with chronic heart failure is taking digoxin. To reduce the side effects
of digoxin the doctor adviced him to combine it with:
A.*Pananginum
B.Calcii gluconas
C.Euphyllinum
D.Dichlothiazidum
E. Calcium chloridum
49 Which is the main mechanism of action of benzilpenicillinum which provides antibacterial
effect against the coccus flora?
A.*Inhibition of cell wall synthesis
B.Inhibition of protein synthesis
C.Impairment the permeability of the cytoplasmatic membrane
D.Activation of immune system of a macroorganism
E.Stimulation
of
phagocyte’s
activity
of
leucocytes
50 A patient suffering from neurosis with fear and anxiety was administered Diazepam. Which
pharmacological effect allows it to be used to treat these symptoms?
A.*Anxiolytic
B.Antiarrhythmic
C.Anti-inflammatory
D.Hypotinsive
E. Antianginal
51 A patient with disturbances of cardiac rhythm was given lidocaine. Which pharmacological
effect except local anesthesia does this preparation have?
A.*Antiarrythmic
B.Hypnotic
C.Anti-fever
D.Antidepressive
E. Nootropic
52 A patient with acute intoxication needs a forced diuresis. Which drug should be used?
A.* Furosemidum
B.Caffeine-natrium benzoas
C.Galantaminum hydrobromidum
D.Enalaprilum
E. Pyracetamum
53
A patient who has suffered a brain trauma, was prescribed Piracetam. Which
pharmacological group does this preparation belong to?
A.*Nootropic drugs
B. Non-narcotic analgesics
C.Tranquilizers
D.Drugs for narcosis
E. Neuroleptics
54 For aterosclerosis treatment a patient in a pharmacy bought hypolipidemic agents of the
fibrates group. Name the preparation.
A.*Fenofibrate
B.Drotaverinum hydrochloridum
C.Bisacodilum
D.Spironolactonum
E. Siliborum
55 To prevent attack of angina pectoris a patient is taking Nitroglycerine in capsules. Which is
the rational way of taking this medicine?
A.*Sublingual
B.Peroral
C.Rectal
D.Inhaled
E. Subcutaneous
56 A child is delivered to the hospital with signs of belladonna alkaloids intoxication. Which
preparation should be immediately used as an antidote?
A.*Proserine
B.Magnesium sulfatis
C.Caffeine
D.Paracetamol
E. Valproate sodium
57 A doctor prescribed a patient with chronic constipation the preparation Bisacodyl. After 3
weeks of treatment the patient noticed the laxative effect diminished. Which side effect is this
associated with?
A.* Addiction
B.Sensibilisation
C. Accumulation
D. Dysbiosis
58 Advice a patient with acute bronchitis, a mucolytic preparation with expectorant action.
A.*Acetylsysteinum
B.Glaucinum
C.Loratadinum
D.Diclophenac-sodium
E. Drotaverinum hydrochloridum
59 You are an employee in a pharmaceutical warehouse. While entering received preparations
into the computer name the category of preparations into which you would write Paracetamol.
A.*Non-narcotic analgesic
B.Hypnotic drug
C.Diuretic drug
D.Hypotensive drug
E. Antianginal drug
60 A patient with stenocardia (angina pectoris) received a prescription Metoprolol. Which
pharmacological effect allows us to use this preparation for stenocardia treatment?
A.*Antianginal
B.Hypotensive
C.Antiarrythmic
D.Antiplatelet
E. Broncholytic
61 Due to weakness of labor activity a doctor prescribed the woman a hormonal preparation to
stimulate the delivery. Name this preparation.
A.*Oxytocin
B.Glibenclamide
C.Prednisolone
D.Insulin
E. L-thyroxin
62 Answer the question of your collegue, the provisor. Which non-steroid drug belongs to the
selective COX-2 blockers?
A.*Celecoxib
B.Analginum
C.Paracetamol
D.Diclophenac-sodium
E. Acidum acetylsalicylicum
63 Answer a nurse's question. Hypoglycemic action of which preparation is the result of
stimulating of beta-cells of the pancreas?
A.*Glibenclamide
B.Prednisolone
C.Adrenalin hydrochloride
D.Retabolilum
E. Heparin
64 An old patient the post-opertive intestinal atonia was developed. Which anticholinesterase
drug does he need?
A.*Proserinum
B.Dithylinum
C.Pilocаrpinum hydrochloridum
D.Atropine
E. Metoprolol
65 A patient with Parkinson disease a preparation with dominante influence on the
dophaminergic system was prescribed. Name this preparation.
A.*Levodopa
B.Zopiclon
C.Droperidolum
D.Aminazinum
E. Lorazepamum
66 A patient with exacerbation of urolithiasis and kidney colic was delivered to the emergency
department with kidney colic. Which preparation should be given to remove the colic?
A.*Drotaverine
B. Silibor
C. Almagel
D. Aethymisolum
E. Proserinum
67 Patient N. 56 years old цшер ischemic heart disease was given Metoprolol. What is the
mechanism of beta-adrenoblocker's action in case of ischemic heart disease?
A. *Decrease oxygen demands of myocardium
B. Increase oxygen demands of myocardium
C. Dilate coronary blood vessels
D. Decrease tone of peripheral vessels
E. Constrict coronary vessels
68 A patient with allergic dermatitis came to the hospital. Which preparation with antiinflammatory and anti-allergic properties should be prescribed?
A. * Prednisolone
B.Аethamidum
C.Oxytocin
D.Insulin
E. Retabolilum
69 A patient with atherosclerosis was given an anti-atherosclerotic preparation. Name it.
A. * Phenofibrate
B.Ascorbic acid
C.Pyracetam
D.Dexamethasonum
E. Butadionum
70 Angioedema (Quincke's edema) was developed in a patient after bee bites. Which
preparation should be immediately injected to remove the allergic reaction?
A.*Adrenalini hydrochloridum
B.Natrii chloridum
C.Plathyphyllini hydrotartras
D.Atropini sulfas
E. Anaprillinum
71 A 55 year old man complains of insomnia, irritation and weakness. Which the preparation
from listed below is reasonable to give to the patient in this case?
A.*Nitrasepam
B.Aminazinum
C.Triftazinum
D.Droperidol
E. Amitriptyline
72 A patient with hypertonic disease was given Metoprolol to reduce the blood pressure. What
is the mechanism of its action?
A.*Blockade of beta-adrenoreceptors
B.Blockade of alfa-adrenoreceptors
C.Indirect adrenomimetic action
D.Spasmolytic action
E. Blockade of angiotensine receptors
73 A patient with bronchial asthma in order to eliminate attack was given a preparation which
stimulates predominantly beta-2-adrenoreceptors. Name this preparation.
A.*Salbutamol
B.Adrenalini hydrochloridum
C.Droperidol
D.Clophellinum
E. Isadrinum
74 A patient with Parkinson disease to remove the muscle rigidity was prescribed a preparation
which is a precursor of dophamine. Name this preparation.
A. *Levodopa
B.Aminazinum
C.Paracetamol
D.Scopolamini hydrobromidum
E. Atropini sulfas
75 A patient with neurosis was given an anxiolytic drug that is derivative of benzodiazepine.
Name this preparation.
A.* Diazepam
B.Atropini sulfas
C.Piroxicam
D.Retabolilum
E. Cyclodolum
76 A 34 year old patient with bronchitis the doctor prescribed an anti tussive preparation with
central action. What is the drug?
A.*Glaucinum
B.Corglycon
C.Enalapril
D.Furosemidum
E. Fercovenum
77 To patient with insulin independent diabetes mellitus the synthetic antidiabetic drug of
sulfonylurea group was appointed. Name this drug.
A. *Glibenclamide
B. Insulin
C. Anaprylinum
D. Prednisolone
E. Furosemide
78 Help the physician to choose the drugs of NSAID group which is an inhibitor of COX-2 and
does not damage the stomach.
A. *Celecoxib
B. Acetylsalicylic acid
C. Indomethacin
D. Paracetamol
E. Diclofenac sodium
79 Explain the doctor what is correctly call the phenomenon of reducing of the drug
effectiveness in long term using:
A. *Habituation
B. Sensitization
C. Accumulation
D. Dependence
E. Tachyphylaxis
80 Patient warned that the use of the drug that was prescribed, you may cough. Name this drug.
A. *Lisinopryl
B. Clophelinum
C. Phenihydin
D. Dichlothiazidum
E. Metoprolol
81 The loop diuretic for forced diuresis was appointed to a patient with acute poisoning. What is
this medicine?
A. *Furosemide
B. Mannit
C. Dihydrochlorthiazid
D. Triamteren
E. Spironolactone
82 Lisinopril was appointed to a patient with hypertension. What is a typical side effect that its
inherent?
A. *Dry cough
B. Constipation
C. Increased appetite
D. Insomnia
E. Vomiting
83 Physician said to pharmacist: "Remind me, my colleagues, what so called phenomenon that
one drug enhances the effect of the other":
A. *Potentiation
B. Antagonism
C. Sensitization
D. Abstinence
E. Tachyphylaxis
84 Consult medical intern, why Antacids should not use together with iron preparations?
A. *Deceleration of absorption of iron preparations
B. Increases binding to blood proteins
C. Violated deposition of iron in the body
D. Amplifies iron intoxication
E. Accelerated elimination of iron preparations
85 A patient for treatment of pneumonia appointed doxycycline hydrochloride. Which group of
antibiotics includes this drug?
A. *Tetracyclines
B Aminoglycosides
C. Macrolides
D. Cephalosporins
E. Penicillins
86 You are the pharmacist of the pharmacy. Which group of broncholytics should order to
pulmonology department for treatment of patients with asthma?
A. *Beta2-adrenomimetics
B Beta-blockers
C. M-cholinomimetics
D. N-cholinomimetics
E. Anticholinesteraze drugs
87 Dobutamine was introduced to the patient with acute heart failure and intolerance to cardiac
glycosides. What is the mechanism of action of this drug?
A. *Stimulation of beta 1-adrenoceptors
B. Stimulation of alpha-adrenergic receptors
C. Blockade of K+/ Na+/ ATPase
D. Inhibition of activity of phosphodiesterase
E. Stimulation of M-cholinoreceptors
88 The doctor has prescribed the drug to the patient for the treatment of thrombosis. The drug
was from the group of anticoagulants of direct action. Name this drug.
A. *Heparin
B. Pheniline
C. Syncumar
D. Neodicumarine
E. Vicasol
89 A doctor has appointed a cardiac glycoside from a group of digitalis to the patient with
chronic heart failure. Name this drug:
*A. Digoxin
B. Strophanthin
C. Corvalolum
D. Corglycone
E. Cordiaminum
90 Anaphylactic shock was developed in the patient after vaccination. Name the drug of choice
for urgent help?
A. *Adrenaline hydrochloride
B Anaprylin
C. Naphthyzinum
D. Salbutamol
E. Dithylinum
91 Elderly patients suffering constipation, which is based on hypotonia of a thick intestine.
Which drug should be appointed to the patient for treatment of the constipation?
A. *Bisacodyl
B. Sodium sulfate
C. Castor oil
D Atropini sulfate
E. Novocainamide
92 A doctor has appointed mucolytic drug to the patient with acute bronchitis. Name it.
A. *Acetylcysteine
B. Glaucine
C. Codeine phosphate
D. Ethymizol
E. Bemegride
93 Woman has a bad sleep after suffering a stress. Which of these hypnotic drugs should be
preferred to treat insomnia?
A. *Nitrazepame
B. Phenobarbital
C. Chloral hydrate
D. Aminazynum
E. Barbitalum
94 In the addicts after the expiration of drug acting the severe mental, neurological and somatic
disorders arise. What is the name of this symptom?
A. *Abstinence syndrome
B. Idiosyncrasy
C. Sensitization
D. Cumulation
E. Tolerance
95 Woman 65 years old with mandibular fractures takes narcotic analgesic. Name of this drug.
A. *Promedole
B. Pyracetamum
C. Heparin
D. Cinnaryzyne
E. Furosemide
96 Patient with hypertensive disease takes the drug of the nonselective beta-adrenoblockers
group. Name this drug.
A. *Anaprylin
B. Prazosin
C. Proserinum
D. Epinephrine hydrochloride
E. Labetalol
97 Which drug should enter as the antidote to the patients with acute morphine poisoning?
A. *Naloxone
B. Lobelini hydrochloridum.
C. Bemegride.
D. Atropini sulfas
E. Unitiolum
98 For treatment of glaucoma a doctor decided to direct cholinomimetic drug of direct action.
What is this medicine?
A. *Pilocarpini hydrochloridum
B. Zinc sulfate
C. Sulfacylum-natrium
D. Platyphyllini hydrotartras
E. Atropini sulfas
99 In process of pharmacotherapy of bronchitis dyspeptic disorders, photodermatitis and liver
dysfunction arise in the patient. Which drug is designed to the patient could cause these effects?
* A. Doxycycline
B. Paracetamol
C. Ascorbic acid
D. Acetylcysteine
E. Codeine phosphate
100 The patient suffers from gall-stone disease. Which drug should be appointed to removal of
hepatic colic?
A. *Magnesium sulfate
B. Amalgel
C. Contrical
D. Bisacodyl
E. Pancreatin
101 Help the doctor to choose the narcotic analgesic that can be used for anesthesia of delivery?
A. *Promedolum
B. Paracetamol
C. Codeine phosphate
D. Fentanyl
E. Analginum
102 A patient with a diagnosis of stomach ulcer in the acute phase was hospitalized. Consult
medical intern, what is the drug reduces the function of stomach glands by blockade of H2receptors:
A. *Famotidine
B. Belladonna dry extract
C. Metacynum
D. Atropini sulfate
E. Platiphyllini hydrotartras
103 Choose on the pharmacy stock anticholinesteraze drug of reversible action for the surgery
department for patients with intestine and urinary bladder atonia in the postoperative period
A. *Proserinum
B. Phosphacolum
C. Benzohexonium
D. Atropini sulfas
E. Dithylinum
104 The patient asked the pharmacist to give the drug that treats the headache and has
antiplatelet action. Name this medicine.
A. *Acetylsalicylic acid
B. Codeine phosphate
C. Promedolum
D. Tramadol
E. Fentanyl
105 Came the order from the surgery department to the hospital pharmacy to receive the drug of
the group of depolarizing myorelaxants for surgical interventions. What medicine was ordered?
*A. Dythylinum
B. Nicotine
C. Atropini sulfas
D Metacynum
E. Hygronium
106 A doctor recommended to take acetylsalicylic acid during 3-4 months to the patient who
suffered acute myocardial infarction. On what is the action of acetylsalicylic acid the doctor
hoped?
A. *Anti-platelet
B. Antipyretic
C. Analgesic
D. Anti-inflammatory
E. Antispasmodic
107 The doctor-intern asked the pharmacist for advice, which drug is better to take the patient
with amebic dysentery. Name this drug.
A. *Metronidazole
B. Pirantel
C. Levomizolum
D. Bicillinum -5
E. Benzylpenicillinum sodium
108 During the surgical intervention with the application of neuromuscular blocking agent
tubocurarine the respiratory violation is developed in the patient, and this violation was
eliminated after the introduction of Proserinum. What is the name of this interaction between
the drugs?
A. *Antagonism
B. Accumulation
C. Incompatibility
D. Tachyphylaxis
E. Synergism
109 The hypercromic anemia was revealed in the patient that a long time suffered a stomach
diseases. What the drug is used for treatment of this disease?
A. *Cyanocobalamine
B. Ascorbynic acid
C. Unytyolum
D. Ferrum Lek
E. Охуferriscorbonе sodique
110 There is the woman of 25 years old with the phenomenon of acute morphine intoxication.
Naloxone was introduced her and it caused the improving of her condition. What is the
mechanism of action of this drug?
A. *Blockade of opioid receptors
B. Blockade of GABA receptors
C. Serotonin receptors blockade
D. Blockade of dopamine receptors
E. Blockade of benzodiazepine receptors
111 To narcological department a patient with morphinism was hospitalized. The doctor
appointed the reduction of pharmacological activity of morphine. What is the phenomenon of
reducing the effect of morphine in the re-introduction?
A. *Habituation
B. Material accumulation
C. Functional accumulation
D. Antagonism
E. Summation
112 Drug of choice for treatment of trichomoniasis is:
A. *Metronidazole
B. Oletetrinum
C. Norfloxacin
D. Nistatin
E. Claforan
113 Select a drug for treatment of bronchial asthma from the group of α2-adrenostymulators.
A. *Salbutamol
B. Euphylin
C. Atrovent
D. Ketotifen
E. Beclometasone
114 The antipsychotic drug was assigned to the patient with schizophrenia. Which drug of the
following drugs belongs to this group?
A. *Aminazynum
B. Celecoxib
C. Anaprylin
D. Morphine
E. Piracetamum
115 A student with a request addressed to a pharmacy to advise the drug for elimination of
manifestations of allergic rhinitis, which occurs during of the flowering Limes. Which drug can
be applied?
A. *Loratadine
B. Adrenaline
C. Anaprylinum
D. Ambroxol
E. Losartan
116 There is the patient with stomach ulcer. The drug which of these groups need to use in
complex therapy of the patient?
A. *H2 blockers of histamine receptors
B. H1 blockers of histamine receptors
C. β2-adrenoblockers
D. β1-adrenoblockers
E. β1 β2-adrenomimetics
117
The patient with rheumatic arthritis and ulcer of duodenum need in Non steroid antiinflamatory
drug. Which drug is the drug of choice in this instance?
A *Celecoxib
B Acetylsalicylic acid
C Paracetamol
D Analginum
E Diclofenac
118
The doctor appointed the drug to the patient with ischemic heart disease to quickly relieve
angina attacks. This drug must be used sublingually. Select this drug of proposed.
A * Nitroglycerine
B Corglycon
C Isosorbide mononitrate
D Lisinopril
E Amiodarone
119
During the test on the sensitivity to benzylpenicillin anaphylactic shock was developed in the
patient. What preparation is necessary to prick all round the place of introduction of antibiotic?
A * Epinephrine
B Norepinephrine
C Atropine
D Propranolol
E Ceftriaxon
120
Name the drug which belongs to the group of tetracyclines that was assigned to the patient to
treat bronchitis:
A * Doxycyclin
B Benzylpenicillinum sodium
C Aciclovir
D Isoniazid
E Chloroquine
121
For the treatment of atherosclerosis in a patient acquired pharmacy lipid-lowering drug
fenofibrate. Which pharmacological group is this drug?
A * Fibrates
B Nitrofurans
C Calcium channel blockers
D β2-adrenergic blockers
E M-holinoblokatory
122
Remind your colleague as a pharmacist is the phenomenon when one drug reduces the effect of
the other?
A * Antagonism
B Addiction
C Sensitization
D potentiation
E tachyphylaxis
123
Explain to your colleague pharmacist what indications for naloxone?
A * Acute poisoning with narcotic analgesics
B Heavy metal poisoning
C poisoning cardiac glycosides
D poisoning with ergot alkaloids
E poisoning atropine sulfate
124
The patient for the treatment of asthma, your doctor has prescribed a drug from the group
beta-agonists. Specify this drug?
A * Salbutamol
B Diazepam
C Doxycycline hydrochloride
D Nitroglycerin
E Digoxin
125
Which of the following drugs for sublingual application quickly relieves angina?
A * Nitroglycerin
B Digoxin
C Amiodarone
D Lisinopril
E Korglikon
126
By what pharmacological effect of diazepam is used to treat neuroses?
A * anxiolytic
B analgesic
C diuretichesky
D antipyretic
E antidepressant
127
You - the pharmacist, the intern. Upon delivery of the test exam choose from the
pharmacological effects of the one that allows the use of chlorpromazine in the treatment of
psychosis?
А*Antipsychotic
B hypothermic
C antiinflammatory
D Antiemetic
E Spasmolytic
128
Answer the question my colleague pharmacist what the mechanism of action of NSAIDs
celecoxib?
A * Selective inhibition of COX-2
B Blockade ACE
C Stimulation of M-cholinergic receptors
D blockade of H2-histamine receptors
E Stimulation adrenoreceptors
129
Answer the question of a young doctor: how is the ability of drugs
accumulate in the body of the patient?
A * Cumulation
B Antagonism
C Synergy
D Habituation
E Allergy
130
You pharmacist, choose from the collection of your pharmacy drugs one that
refers to a fat-soluble vitamin preparations
A * Retinol acetate
B Oxytocin
C Acyclovir
D Heparin
E Dimedrolum
131
Help a young doctor to choose the best of you at the pharmacy chemotherapeutic
means a drug for the treatment of a patient suffering from herpes
A * Acyclovir
B Rifampicin
C Doxycycline hydrochloride
D Hingamin
E Metronidazole
132
Help a young doctor to choose the best of you at the pharmacy chemotherapeutic
means a drug for the treatment of a patient suffering from herpes
A * Acyclovir
B Rifampicin
C Doxycycline hydrochloride
D Hingamin
E Metronidazole
133
Patient with glaucoma doctor prescribed neostigmine in the form of eye drops. To which
pharmacological group is this drug?
A * Antiholinesterazny reversible actions
B M-anticholinergic
C-H cholinomimetic
D β2-adrenergic blocker
E β2-adrenoagonists
134
What drug from the group of local anesthetics used in patients with heart rhythm disorder?
A * Lidocaine
B Paracetamol
C Morphine hydrochloride
D Caffeine-sodium benzoate
E Nitrazepam
135
Patient with renal colic appointed antispasmodic with group M-cholinergic antagonists.
A * Atropine
B Neostigmine
C galantamine
D Ditilin
E benzogeksony
136
Used in the treatment of arrhythmia nonselective - β-blocker.
A * Inderal
B Atenolol
C Phentolamine
D Prazosin
E reserpine
137
The patient was in a state of psychosis assigned antipsychotic.
A * Aminazin
B Diazepam
C Cyclodol
D Caffeine
E Phenobarbital
138
Fear of emotional stress in the patient neurosis allowed doctor to prescribe that will reduce these
symptoms.
A * Diazepam
B Lithium Carbonate
C Sidnokarb
D Nootropil
E Caffeine
139
Patient on asthma was appointed drug-salbutamol, after which he disappeared bronhospazma.Eto
symptoms associated with stimulation:
A * β2-adrenoceptor
B α1-adrenoceptor
C M-cholinergic receptors
D synthesis of acetylcholine
E β1-adrenoceptor
140
After prolonged use of isosorbide to prevent strokes patient noted a decrease effect. What
pharmacological phenomenon occurred?
A * Tolerance
B Kummulyatsiya
C Physical dependence
D Allergy
E Potentiation
141
When the weakness of labor appoint:
A * Oxytocin
B Nospanum
C Progesterone
D Vikasol
E Fenoterol
142
Patient for the prevention of thrombus formation in ischemic heart disease was assigned
medication with NSAIDs group.
A * acetylsalicylic acid
B Ibuprofen
C piroxicam
Mefenamic Acid D
E Indomethacin
143
Patients with myocardial infarction were injected intravenously anticoagulant direct action.
A * Heparin
B neodikumarina
C Vikasol
D Thrombin
E calcium gluconate
144
Select an antibiotic for the treatment of syphilis.
A * Penicillin
B Streptomycin
C Kanamycin
D Amphotericin
E Nystatin
145
Trichomoniasis diagnosed. What you need to apply an antimicrobial agent?
A * Metronidazole
B Ampicilin
C Chloroquine
D Nystatin
E Gentamicin
146
The patient appeared cold sores on the skin. What preparation is necessary to apply?
A * Acyclovir
Gentamicin B
C clotrimazole
D Benzilpenitsilin
E Biseptol
147
For individual malaria prevention medication was appointed.
A * Hingamin
B Rifampicin
C Ampicillin
D Gentamicin
E Biseptol (Ko- trimoxazol)
148
Letting go of pharmacy glaucine hydrochloride patient with chronic bronchitis about what a
typical side effect to warn the patient?
A * Lowering blood pressure
Excitation of CNS B
C Cardiac arrhythmias
D Increased intraocular pressure
E Allergic skin rash
149
The patient for the treatment of atopic dermatitis after bee stings assigned loratadin.Kakoy
protivoalergicheskogo mechanism of drug action?
A * Inhibition of H1-histamine receptors
B Inhibition of H2-histamine receptors
C Blockade of C-leukotriene receptor D4
D Reducing the release of leukotriene D
E antiserotoninovoy activity
150
The doctor suspected cholera patient appointed doxycycline gidrohlorid.K which group danyj
drug?
A * Tetracyclines
B penicillin
C cephalosporin
D Cyclic polypeptides
E Macrolides and azalides
151
Which of holinotropnyh drugs used in glaucoma to reduce intraocular pressure?
A * Pilocarpine
B Atropine
C Platifilin
D Scopolamine
E Metacin
152
30 years old patient with sleep and rastrojstvo imbalance psihoemotsialnoy sphere doctor
prescribed diazepam. What caused psychosedative effect of the drug?
A * Activation of GABAergic system
B Deceleration limbic system
C Deceleration reticular formation
D Reducing the amount of norepinephrine in CNS
E Deceleration opioid receptors
153
Why not benzilpenitsilina sodium salt is used inside?
A * Destroyed gastric HCl
B is poorly absorbed in the gut
C irritate the stomach
D Reduces the formation of gastric HCl
E Destroyed penitsilinazoy
154
Advise your doctor if bleeding caused by prolonged use of neodikumarina, drug antagonist.
A * Vikasol;
B Aminocaproic acid;
C Etamzilat;
D Fibrinogen;
E Ascorbinic acid.
155
The woman protracted period of generic drugs listed deyatelnosti.Iz Whyber one that thanks to
physiological action will stimulate labor.
A * Oxytocin;
B Neostigmine;
C pahikarpin;
D Progesterone;
E Estron.
156
Patient 48-years to remove a severe attack of asthma intravenous injections of prednisolone
solution. To which group belongs gormon drugs prednisolone?
A * glucocorticoids;
B Progesteron drugs;
C Estrogen preparations;
D mineralocorticoid;
E Anabolic Steroids.
157
Consult a doctor-intern: which drug is the drug of choice for treatment of syphilis?
A * Benzylpenicillin sodium salt;
B Lincomycin hydrochloride;
C levorin sodium salt;
D Streptomycin sulfate;
E Polymyxin M sulfate.
158
You pharmacist consultant working in a pharmacy. Advise patients with acute exacerbation of
rheumatoid arthritis analgesic anti-inflammatory drug, which is a lesser extent will affect the
gastric mucosa
A * Celecoxib;
B Diclofenac Sodium;
C acetylsalicylic acid;
D Ibuprofen;
E Indomethacin.
159
You - Pharmacist Pharmacy. For design showcases diuretics select
"Loop" diuretics emergency, strong and short steps:
A * Furosemide;
B Klopamid;
C Diakarb;
Spironolactone D;
E Triamterene.
160
Consult a young psychiatrist: what means can be used to treat psychosis?
A * Aminazin
B sulfokamfokain
C sodium bromide
D Diphenhydramine
E Analginum
161
Help the doctor to choose the optimal route of administration Korglikon the treatment of acute
heart failure.
A * Intravenous
B Rectal
C Subcutaneous
D Inside
E Inhaled
162
Physician for the purpose of diagnostic endoscopy depolarizing muscle relaxant introduced to
the patient type of action. Name this drug.
A * Ditilin
B Morphine hydrochloride
C Caffeine-sodium benzoate
D Metoprolol
E Loratadin
163
To neurologist approached by a woman with complaints of poor sleep, feelings of fear, anxiety.
Which means you want to assign?
A * Diazepam
B Levodopa
C Nitroglycerin
D Oxytocin
E Lisinopril
164
Give your answer to the question of student-trainee: what drug you want to assign to the patient
with postoperative intestinal atony?
A * Neostigmine
B Salbutamol
C Paracetamol
D furasemid
E Hingamin
165
Select a drug that belongs to a non-selective beta-blockers.
A * Inderal
B Metoprolol
C Epinephrine hydrochloride
D Neostigmine
E Atropine
166
What medication synthetic origin with a group hydrazides prescribed for
tuberkuloze lungs?
A * Isoniazid
B Rifampicin
C Acyclovir
D Metronidazole
E Doxycycline hydrochloride
167
Which drug is appropriate to introduce in acute heart failure?
A * Korglikon
B Salbutamol
C Pilocarpine hydrochloride
D Naloxone
E Heparin
168
Pharmacy approached by a woman who has appeared on the upper lip herpes. Suggest a drug for
treatment.
A * Acyclovir
B Isoniazid
C Glibenclamide
D Hingamin
E Metronidazole
169
On pharmaceutical warehouse received analgesics. What are the application of any drug may
develop drug dependence?
A * Promedol
B acetylsalicylic acid
C Naloxone
D diclofenac sodium
E Paracetamol
170
Patient with coronary heart disease doctor has ordered the drug from the group of beta1adrenergic blockers. Name this drug.
A * Metoprolol
B Morphine
C droperidol
D Salbutamol
E Benzylpenicillin sodium salt
171
Student with a cold doctor appointed antipyretic drug. Name this drug.
A * Paracetamol
B Ascorbic Acid
C Oxytocin
D famotidine
E Cyanocobalamin
172
The patient developed allergic dermatitis after eating citrus.
Advise drug group with H1-blockers gistaminoblockers.
A * loratidine
B acetylsalicylic acid
C Vikasol
D Diclofenac sodium
E Retinol acetate
173
In the Patient found megaloblastic hyperchromic anemia. Suggest a drug for the treatment of
this pathology.
A * Cyanocobalamin
B Ascorbic Acid
C Salbutamol
D bisacodyl
E Vikasol
174
What drug group with cardiac glycosides is indicated for the treatment of chronic heart failure?
A * Digoxin
B Prednisolone
C. Magnesium sulfate
D Fenofibrate
E Heparin
175
What drug is indicated for muscle relaxant overdose depolyariziruyuschego type of action?
A * Neostigmine
B Metoprolol
C Naloxone
D Magnesium sulfate
E Unitiol
176
In the emergency department admissions with symptoms of mercury poisoning. What antidote is
shown in this case?
A * Unitiol
Atropine sulfate B
C Neostigmine
D Naloxone
E Calcium chloride
177
Man with a fracture of the femur for pain medication was appointed. Call it a drug.
A * Morphine hydrochloride
B diphenhydramine
C acetylsalicylic acid
D Paracetamol
E Caffeine-sodium benzoate
178
Consult doctor which of the drugs at your pharmacy can
used in the treatment of glaucoma?
A * Pilocarpine Hydrochloride
B. Atropine sulfate B
C acetylsalicylic acid
D Promedol
E Diazepam
179
To you the pharmacy patient appealed for advice on the bronchospasm. what
drug should be assigned to the patient?
A * Salbutamol
B Oxytocin
C Insulin
D Vikasol
E bisacodyl
180
Name drug that constricts the pupil and lowers intraocular pressure.
A * Pilocarpine Hydrochloride
B Fenofibrate
C Nitrazepam
Atropine sulfate D
E Ditilin
181
Name drug with a group of anticholinesterases used in patients in the postoperative period in
order to stimulate peristalsis
A * Prozerine
B Epinephrine hydrochloride
C Metoprolol
D Salbutamol
E Ditilin
182
Doctor appointed patient drug used to treat bleeding. What preparation is appointed doctor?
A * Vikasol
B Insulin
C Metoprolol
D Heparin
E Dihlotiazid
183
Pharmacy approached by a woman complaining of a change in urine color to red. what
anti-TB drug has caused such an act?
A * Rifampicin
B Isoniazid
C Streptomycin
D Doxycycline hydrochloride
E Hingamin
184
In the hospital the patient is on diabetes, which developed after the introduction of insulin
hypoglycemic coma. What drug can rapidly improve her condition?
A * Epinephrine hydrochloride
B Atropine
C Anaprilin
D Metoprolol
E Glibenclamide
185
Call H2-histamine blockers, used in the treatment of peptic ulcer
stomach with increased secretion.
A * famotidine
B Atropine sulfate
C Neostigmine
D dobutamine
E Loratidin
186
Patients with acute bronchitis was appointed with an antibacterial drug group
beta-lactam antibiotics. Name this drug:
A * Benzylpenicillin sodium salt
B Doxycycline hydrochloride
C Rifampicin
D Metronidazole
E Gentamicin
187
Doctor wrote a patient antiplatelet agents affecting platelet thromboxane formation. Name this
drug.
A * acetylsalicylic acid
B Vikasol
C Epinephrine hydrochloride
D Calcium chloride
E Prednisolone
188
Doctor wrote a patient on asthma medication s group of adrenal hormones. Name this drug.
A * Prednisolone
B Loratidin
C Sodium Diclofenac
D Salbutamol
E Atropine sulfate
189
Specify a hormonal drug to induce labor.
A * Oxytocin
B Progesterone
C Salbutamol
D Dexamethasone
E Metoprolol
190
Doctor appointed patient drug metoprolol, which helped to reduce high blood pressure. Which
pharmacological group applies this tool?
A * Beta-blockers
B Alpha adrenoblockers
C M-cholinolytics
D H anticholinergics
E Sipmatolitiki
191
Invited conference on medical clinical pharmacist informed the antiviral drug acyclovir. What is
its mechanism of action?
A * Inhibits synthesis of nucleic acids
B blocks the synthesis of cell wall
C increases the permeability of the cell membrane
D Has antagonism s PABA
E Inhibits protein synthesis
192
Asked the pharmacist to recommend a drug with antiprotozoal
H. pylori activity. What preparation is recommended specialist?
A * Metronidazole
B Isoniazid
C Rifampicin
D Acyclovir
E Benzilpenitsilina natrievyaa salt
193
What are the drug of first choice in overdose narcotic analgesics.
A * Naloxone
B Caffeine-sodium benzoate
C Diazepam
D Unitiol
E Calcium chloride
194
Name the drug reduces the frequency and force of heart contractions:
A * Inderal
B Amlodipine
Atropine sulfate C
D dobutamine
E Epinephrine hydrochloride
195
Due to chest injuries in men's heart stopped. These preparations which are administered into the
cavity of the left ventricle in such a situation.
A * Epinephrine hydrochloride
B Salbutamol
C Lisinopril
D Neostigmine
E Metoprolol
196
Middle-aged woman approached the pharmacist with a request to release the drug to relieve an
angina attack. Name this drug.
A * Nitroglycerin
B Caffeine-sodium benzoate
C Digoxin
D dobutamine
E Epinephrine hydrochloride
197
For the treatment of cerebral edema must assign a diuretic. what drug
you must enter the patient?
A * Furosemide
B Hydrochlorothiazide
C Caffeine-sodium benzoate
D Diakarb
E Spironolactone
198
The patient with pneumonia caused by mycoplasma, appointed doxycycline. Which group
antibiotics include this drug?
A * Tetracyclines
B Penicillin
C cephalosporin
D macrolides
E Lincosamides
199
Patient after removal of the thyroid gland was appointed pozhizneno a L-thyroxine.
What type of pharmacotherapy provides L-thyroxine?
A * Replacement
B Pathogenic
C Etiotropic
D Stimulating
E Preventive
200
Among psychotropic drugs, that you might have in the pharmacy, select a drug that blocks
dopamine receptors.
A * Aminazin
B diclofenac sodium
C Diazepam
D Caffeine-sodium benzoate
E amitriptyline
201
Patient, who for a long time used the drug diclofenac sodium, a family doctor instead appointed
celecoxib. What disease was the cause for replacement drug?
A * Peptic ulcer
B Asthma
C Urolithiasis
D Hypertension
E Chronic hepatitis
202
Which group is the pharmacological anti-ulcer drug famotidine?
A * H2 - histamine
B M-cholinomimetic
C M-anticholinergic
D H anticholinergic
E Antispasmodic myotropic action
203
Patient assigned antitussive drug that depresses the central units viborochno cough reflex, does
not inhibit the respiratory center, does not cause addiction:
A * glaucine hydrochloride
B Codeine phosphate
C acetylcysteine
D Mukaltin
E Bromhexine
204
Select a drug that has a stimulating effect and analeptic:
A * Caffeine-sodium benzoate;
B Neostigmin;
C Diazepam;
D Korglikon;
E Diclofenac Sodium.
205
You - Head of pharmacy. Give your answer to question a pharmacist intern, than due to the
appearance of dry cough in patients who have a long time to treat hypertension taking lisinopril.
A * Increasing concentrations of bradykinin;
B depletion of norepinephrine;
C Accumulation of angiotensin II;
D Inhibition of angiotensin receptor ;
E Reducing the concentration of renin.
206
You - a pharmacist intern. Choose the correct answer with respect to the pharmacological effects
of metoprolol.
A * antianginal, hypotensive;
B Laxative, a vasodilator;
C cardiotonic, hypnotic;
D antiaggregant, antipyretic;
E Antialergichesky, anti-inflammatory.
207
Physician was diagnosed with asthma. Select a drug that can be prescribed to eliminate
suffocation in these terms:
A * Salbutamol;
B Diclofenac Sodium;
Paracetamol C;
D Inderal;
E acetylcysteine.
208
Medicaments which can be used to eliminate the bronchospasm:
A * beta-agonists;
B beta-blockers;
C alpha-adrenergic agonists;
D cholinesterase inhibitors;
E m-cholinomimetics.
209
Select a drug that can be used to eliminate bronchospasm
A * Salbutamol;
B Aspirin;
C atenolol;
D amoxicillin;
E Omnopon.
210
Patient receives levodopa due to Parkinson's disease. What is the mechanism of action of this
drug?
A * precursor of dopamine;
B precursor for steroid hormones;
C blocks the degradation of dopamine;
D precursor of acetylcholine;
E is simpatolitikov.
211
Patient with rheumatoid arthritis 45 years glyukortikoid appointed. Specify this drug.
A * Prednisolone
B ibuprofen
C Mefenamic acid
D insulin
E Analginum
212
Patients with peptic ulcer of fallen 12-ulcer drug from the group taking H2 blockers histamine receptors. Which of the drugs in this group?
A * famotidine
B Gastrotsepin
C Omeprazole
D Almagell
E Alohol
213
Hypertensive patients was appointed a loop diuretic drug fast action, which caused pronounced
hypokalemia. Opredilili this drug.
A * Furosemide
B Mannitol
C Spironolactone
D amiloride
E Triamterene
214
Hypertensive patients in the combined therapy was assigned diuretic that caused hypokalemia.
Define this drug.
A * Hydrochlorothiazide
B amiloride
C Spironolactone
D Allopurinol
E Triamterene
215
55 years old patient was diagnosed with angina. For the treatment was appointed
preparation from the group of calcium channel blockers. Define this drug.
A * Amlodipine
B Atenolol
C oktadin
D reserpine
E Labetalol
216
55 years old patient with an acute attack of angina for its rapid elimination was
appointed drug from the group of organic nitrates. Define this drug.
A * Nitroglycerin
B oktadin
C Nifedipine
D Prazosin
E Labetalol
217
Patient with hypotension doctor prescribed psychomotor stimulant - purine derivative. Define
this drug.
A Caffeine benzoate natrimya
B Diazepam
C Piracetam
D amitriptyline
E Aminazin
218
Consult a physician intern than due to the mechanism of the analgesic action of morphine
hydrochloride:
A * Stimulation of opiate receptors
B blockade of histamine receptors
C blockade of phosphodiesterase
D Stimulation of adenylate cyclase
E blockade cholinesterase
219
Adrenalin is used to extend the infiltration with novocaine
anesthesia. C how the action of adrenaline associated this effect?
A Cuzhenie vessels
B potentiation of novocaine at TSNC
C Inhibition functions of nerve endings and conductors
D Vasodilation
E Inhibition of tissue esterases
220
For the treatment of hives to eliminate itchy skin rashes patient appointed
diphenhydramine. What mechanism ensures its actions?
A Competitive blockade of H1-receptors
B Inhibition of histamine synthesis
C Inhibition of histamine release
D Acceleration destruction of histamine
E Noncompetitive antagonism of histamine
221
To investigate the fundus is necessary to expand the pupil. Indicate the drug, which can be used
for this clinic.
A Atropine
B Acetylcholine
C pilocarpine
D Izadrin
E Norepinephrine
222
Patient marked dryness of mucous membranes, and night blindness. Lack of what vitamin leads
to such symptoms?
A Vitamins A
B Vitamins P
C Vitamins E
Vitamins C D
E Vitamins D
223
What pharmacological effect of diazepam allows its use for the relief of cramps?
A * Anticonvulsant
B analgesic
C antipyretic
D The antiinflammatory
E hypnotics
224
Patient with psychosis assigned antipsychotic, phenothiazine.
Name this drug?
A * Aminazin
B droperidol
C Diazepam
D Levodopa
E Sodium volproat
225
What drug from the group of organic nitrates used for cupping
angina?
A * Nitroglycerin
B verapamil
C Validol
D Caffeine - sodium benzoate
E Digoxin
226
Answer the question nurse. As is the phenomenon where one drug
makes the other?
A * Synergies
B Antagonism
C Sensitization
D Abstinence
E tachyphylaxis
227
What is the correct answer was given a clinical pharmacist at the medical intern Orientation
meeting on the mechanism of anti-atherosclerotic effect of clofibrate (fenofibrate).
A * Lowers triglycerides;
B Inhibits the absorption of cholesterol;
C binds bile acids in the small intestine;
D has an antioxidant effect;
E inhibits the release of free fatty acids from adipose tissue.
228
What preparation of group M - holinomimetikov, you must assign a patient with
glaucoma?
A * Pilocarpine
B Lidocaine
C Atropine sulfate
D dobutamine
E Nitrozapem
229
Patient hyperchromatic B12-deficiency anemia. Preparation of any vitamin must assign?
A * Cyanocobalamin
B Riboflavin
C Vikasol
D Thiamine chloride
E Retinol acetate
230
What non-narcotic antitussive drug central action can be used in dry cough?
A Glaucine A *;
B Codeine;
C acetylcysteine;
D Ambroxol ;
E Mukaltin.
231
Patient with symptoms of chronic bronchitis appointed acetylcysteine. what is the mechanism
expectorant action of the drug?
A * Depolymerisation mucopolysaccharides sputum
B stimulates adrenergic receptors
C Inhibits the cough center
D stimulates the respiratory center
E Anesthesia respiratory mucosa
232
A man diagnosed with Parkinson's disease. What preparation is advisable to appoint a patient?
A * Levodopa
B Nitrazepam
C Paracetamol
D Aminazin
E Anaprilin
233
patient with hypothyroidism doctor has prescribed a drug that exhibits substitution effect. Which
of the following medications prescribed by a doctor?
A * L-thyroxine
B Adrenaline
C Merkazolil
D Amiodarone
E Paracetamol
234
Patients with glaucoma to reduce intraocular pressure doctor prescribed neostigmine in eye
drops. To which group belongs holinotropnyh drugs neostigmine?
A * Antiholinesteraznye;
B Muscle relaxants;
C M-cholinomimetics;
D Ganglioplegic;
E M-anticholinergics.
235
The instructions for medical use on magnesium sulfate to select an effect, allowing you to put the
drug in hypertensive crisis:
A * Antihypertensive
B Laxative
C Anticonvulsant
D Anesthesia
E cholagogue
236
Patient for relief of seizures was appointed group of benzodiazepine drug. Name this drug:
A * Diazepam
B Caffeine sodium benzoate
C Naloxone
D Levodopa
E Suxamethonium chloride
237
Among the pharmacy received chemotherapeutic agents, select
viricide
A Acyclovir
B Benzylpenicillin sodium salt
C Rifampicin
D Isoniazid
E Doxycycline
238
Choose from the pharmacy drugs received by those in cases of poisoning which is used as an
antidote unitiol:
A * Cardiac glycosides
B Aminoglycosides
Atropine sulfate C
D Salbutamol
E Glibenclamide
239
Combined use of furosemide with aminoglycoside antibiotics causes:
A * Ototoxicity
B Increased blood pressure
C Colic
D Sweats
E Increased intraocular pressure
240
Patient 40 years ill with bronchial asthma and heart rhythm disorder in the form of
bradyarrhythmias. Drugs which pharmacological group appropriate to prescribe to eliminate
bronchospasm?
A M-holinoblokatory
B Beta-blockers
C M-cholinomimetics
D anticholinesterases
E Myorelaxants