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Vol 19 #3 - Vancouver Acute Pharmaceutical Sciences
Vol 19 #3 - Vancouver Acute Pharmaceutical Sciences

... 8. Alfacalcidol 2 mcg/mL liquid (One Alpha) • Vitamin D analogue for use in patients with ...
From prescription-only to over-the
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... Most P-category medicines are used in the treatment of minor ailments or injuries, for health promotion, or in palliative care, although the list is beginning to include medicines that are used for acute and chronic conditions that do not fall into these categories and may also be extended to ‘lifes ...
New Drugs and Technologies
New Drugs and Technologies

(Received on 27 /7/2005) (Accepted for publication on 29/4 /2006)
(Received on 27 /7/2005) (Accepted for publication on 29/4 /2006)

... tissues are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Serum calcium concentrat ...
Sympathomimetcs & Parasympatholytics
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... Sympathomimetics Drugs that “mimic” the actions of the sympathetic neurotransmitters Stimulate Alpha, Beta-1, and Beta-2 receptors Also known as Adrenergics or Catecholamines ...
CNS Depressants
CNS Depressants

... drug and sometimes contributes to death due to accidental overdoses - Can cause very alarming and dangerous behavior if not closely monitored • Most problems associated with these drugs due to inadequate professional supervision ...
Neurochemistry of identified motoneurons of the tensor tympani
Neurochemistry of identified motoneurons of the tensor tympani

... The brain was removed and postfixed for one hour in the same fixative, stored overnight at 4 °C in phosphate-buffered 30% sucrose and sectioned serially at 40 lm thickness on a freezing microtome in the frontal plane. Sections were collected in PBS and, for immunohistochemistry, incubated free-floating ...
Macrolide Resistance in Adults with Bacteremic Pneumococcal Pneumonia
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... multidrug–resistant pneumococci has increased in the last 2 decades (3,4). Drug-resistant pneumococci clearly emerge under the selective forces of antibacterial drugs used in the population. Still, the precise nature of these ...
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... Stimulus stretch of neck muscles due to alteration of position of head relative to body Receptormuscle spindles/ pacinian corpuscles in ligaments of cervical joint Response  flexion of forelimbs and extension of hind limbs on ventroflexion of head & vice versa. Flexion of ipsilateral limb and ext ...
Drug abuse and kidney
Drug abuse and kidney

... euphoria induced by inhaling solvents is similar to alcohol intoxication. In addition, solvents can cause hallucinations, of short-term duration (15 to 30 minutes)17 and may develop serious heart, lung, liver, neurological and renal complications, as well as sudden death18. ...
Revisiting the Isobole and Related Quantitative Methods for
Revisiting the Isobole and Related Quantitative Methods for

... versa) in reaching the specified effect level. It is obvious that when drug A is present at 200 mg the quantity of drug B needed is zero, and when drug B is present at 20 mg the quantity of drug A needed is zero. The isobole so derived is based entirely on the relative potency and says nothing about ...
Mar-Apr 2014 - Boston University
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... but over 90% of those in remission continue to drink and over one-third continue to drink at unhealthy levels. Given the ongoing risk of relapse associated with continued drinking, this study suggests a need for ongoing monitoring and maintenance care among patients with a history of an AUD even aft ...
Markers of Central Nervous System Glia and Neurons In Vivo During
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... LEVINE and CARD 1987). Adult oligodendrocyte progenitors are scattered throughout the parenchyma of the brain and spinal cord, but were completely overlooked prior to the availability of in vivo markers speci®c for these cells. A more accurate understanding of CNS cell types and their distinct funct ...
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... Neuropathic Damage to the nervous system: Compression of nerves/spinal cord Infiltration of nerves/spinal cord Chemical damage – chemotherapy/XRT Burning/tingling ...
101 Drugs - Academy of Wellness
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... There are a number of drug classes in the antidepressants. The most common are selective serotonin reuptake inhibitors (SSRIs). Serotonin is a chemical in the brain (neurotransmitter) that makes you feel happy. In people with depression, there is not enough of this neurotransmitter. SSRIs prevent wh ...
INDIGOFERA ASPHALATHOIDES –  Full Proceeding Paper
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... among the world population, there is an increasing trend towards the usage of herbal medicines which may be probably due to the side effects and enormous cost involved in modern medicines. At present people are turning towards the herbal wound healers so as to prevent allergy and other complications ...
Psych Ch. 7 Powerpoint
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... i. Moving one’s focus throughout the body while paying attention to areas that cause pain c) Breath meditation – concentrating on one’s respiration, inhaling and exhaling 2. Most people would benefit from this type of relaxation a) Lowers blood pressure, heart rate, and respiration rate ...
The persistence of maladaptive memory: Addiction
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... the cost of harm from Class A drug use was estimated at £15.4 billion in 2003–2004 (Gordon et al., 2006). This considerable expense would be significantly reduced by implementing successful treatment programmes; for example, it has been estimated that if all heroin addicts complied with methadone tre ...
p. 3 Ans: T - Test Bank Corp
p. 3 Ans: T - Test Bank Corp

... the appearance of long-lasting changes in the brain. On a social level, the pattern of dependence is influenced by the social context in which drug-taking behavior occurs. 4. A drug is typically defined as a chemical substance that, when taken into the body, alters the structure or functioning of th ...
Click here for the PowerPoint presentation
Click here for the PowerPoint presentation

... ◦ Most abundant cannabinoid, contributing up to 40% of cannabis resin. ◦ Does not appear to bind to either CB1 or CB2 ◦ Interacts with ion channels, enzymes, and other receptors ◦ Inhibits cyclooxygenase and lipoxygenase – antiinflammatory and analgesic effects ◦ May be an inverse agonist because se ...
PRODUCT MONOGRAPH ELAVIL® Amitriptyline Hydrochloride
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... Amitriptyline hydrochloride is a tricyclic antidepressant with sedative properties. Its mechanism of action in man is not known. Amitriptyline inhibits the membrane pump mechanism responsible for the re-uptake of transmitter amines, such as norepinephrine and serotonin, thereby increasing their conc ...
IRTRA   Combination Tablets LD/HD
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... long half-life in blood and a 24-hour-lasting blood pressure-lowering effect, having high anti-hypertensive effect in mild to severe hypertension. Based on the large-scale clinical trials, IDNT and IRMA2, which are often cited in the major international guidelines, this drug is also recognized as th ...
Pharmacology Objectives 12
Pharmacology Objectives 12

... Abciximab – inhibits platelet membrane glycoprotein IIb/IIIa receptors, which inhibit the final common path of platelet aggregation. It can be used to prevent reooclusion and restenosis following coronary angioplasty and atherectomy (high bleeding risk). Dipyridamole w/asprin – inhibits adenosine up ...
Alcohol and Other Drugs Alcohol and Other Drugs
Alcohol and Other Drugs Alcohol and Other Drugs

... asked to mark as true, false, or unsure. You will need to print enough copies for the group beforehand. ...
Complex Formation Chapter 33 Thorsteinn Loftsson, and Marcus E. Brewster,
Complex Formation Chapter 33 Thorsteinn Loftsson, and Marcus E. Brewster,

... antigen—antibody) or 3) type of structure formed (e.g., self-assembled aggregate, micelle, clathrate, and inclusion complex). Molecular complexes consist of one or more substrates and ligands that are, in general, held together by relatively weak, noncovalent forces. In aqueous solutions, free molec ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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