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REDUCING OF ERROR IN THE MEDICATION PROCESS OF A PRIVATE... NORTHEAST OF THAILAND  Original Article
REDUCING OF ERROR IN THE MEDICATION PROCESS OF A PRIVATE... NORTHEAST OF THAILAND Original Article

... the same place or near each other, make confusion occur. The Pharmacy Department modified drug shelf and rearrange drugs alphabetically with tall man letter especially for LASA drug [9]. In addition, the pink reflect sticker was used for identified and is of concern for both pharmacists and pharmaci ...
Management of Status Epilepticus D. DURHAM
Management of Status Epilepticus D. DURHAM

... intubation and mechanical ventilation) may be used (see below) for 12 hours before withdrawing and observing for signs of a return in seizure activity. Magnesium sulphate Magnesium sulphate is used to control seizures associated with eclampsia (10 - 15 mmol intravenously over 5 minutes, followed by ...
An Introduction to Medicinal Chemistry
An Introduction to Medicinal Chemistry

... distinctly dangerous. Morphine is one such example. It is an excellent analgesic, yet it suffers from the serious side-effects of tolerance, respiratory depression, and addiction. It can even kill if taken in excess. Barbiturates are also known to be dangerous. At Pearl Harbor, American casualties u ...
Clinical Toxicology: Part I. Diagnosis and Management of Common Drug Overdosage  EY
Clinical Toxicology: Part I. Diagnosis and Management of Common Drug Overdosage EY

... Summary of review: A patient who has taken an overdose of a common drug often presents with an alteration in neurological, cardiovascular and respiratory functions. The differential diagnosis includes, central nervous system injury and metabolic encephalopathies (e.g. hepatic failure, hyponatraemia, ...
INHIBITORY EFFECTS OF ACTIVE CONSTITUENTS AND EXTRACTS OF ANDROGRAPHIS
INHIBITORY EFFECTS OF ACTIVE CONSTITUENTS AND EXTRACTS OF ANDROGRAPHIS

... Results: Our results in general exhibit that AP extracts and constituents potently inhibited UGT1A1 and UGT2B7 with varying degrees of inhibition featuring Ki values from 1.0 upto 7.5 μg/mL. On the other hand, none of them showed significant inhibitory effect on UGT1A4. Of the extracts tested, AP et ...
Close monitoring
Close monitoring

...  Cycles generally were repeated monthly (i.e., allowing a 2week rest period between cycles) for a total of 6–12 cycles.  Dosage was reduced In patients older than 60 years of age & if myelosuppression developed.  There is some evidence that the addition of doxorubicin to a regimen of cyclophospha ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.

... seizure, although there are many types of seizure, some of which have subtle or mild symptoms instead of convulsions. Epilepsy is the second most common neurological disorder after stroke, effecting at least 50 million persons worldwide and approximately 40% of them are women [1]. Epilepsy shows a p ...
27 Gastrointestinal drugs
27 Gastrointestinal drugs

... and therefore inhibits the metabolism of many drugs, increasing their plasma levels and/or bioavailability. These interactions are most likely to be clinically significant for drugs with a narrow therapeutic index. Famotidine, nizatidine and ranitidine do not inhibit cytochrome P450 to a clinically ...
One Step Multi-Drug, Multi-Line Screen Test Device
One Step Multi-Drug, Multi-Line Screen Test Device

... Phencyclidine, also known as PCP or Angel Dust, is a hallucinogen that was first marketed as a surgical anesthetic in the 1950’s. It was removed from the market because patients receiving it became delirious and experienced hallucinations. Phencyclidine is used in powder, capsule, and tablet form. T ...
TED
TED

... Many antibiotics alter the balance of gut flora, thereby enhancing the effect of warfarin Some antibiotics also inhibit the hepatic metabolism of warfarin. These antibiotics include co-trimoxazole, metronidazole, macrolides & fluoroquinolones ...
milk thistle in liver diseases: past, present, future
milk thistle in liver diseases: past, present, future

... flavonoids, phenol derivates, aminoacids, proteins, tocopherol, fat, cholesterol and other substances found in the preparation and (ii) the concentration of the preparation itself (Voinovich et al., 2009). The systemic bioavailability can be enhanced by adding solubilising substances to the extract ...
Antibiotic distribution into the CNS
Antibiotic distribution into the CNS

... The more lipophilic usually the better- although very lipophilic molecules are often highly protein bound or bind to lipid membranes. Diffusion can also be pH dependent ...
Nicotine
Nicotine

... creating an excitatory response. – Some nAChRs also open calcium channels and act on presynaptic nerve terminals. ...
Medical Complications of Cocaine Addiction
Medical Complications of Cocaine Addiction

... Normally, ischemia occurs within minutes to 36 hours after cocaine use (Jaffe, Rawson, & Ling, 2005, Stein, 1999). Most cocaine users with myocardial ischemia or infarction present with chest pain within one-hour post use, at which time drug serum levels are at a peak. In some cases vasoconstriction ...
Rodent Anesthetics and Analgesics
Rodent Anesthetics and Analgesics

... decades of use has characterized many research side effects. Disadvantages: Prolonged recovery time; inadequate analgesic properties; extremely expensive; narrow margin of safety; produces respiratory depression at higher dosages; DEA License required for use as a Class II controlled substance. Opio ...


... formulations are expected to be approved over the next few years. These formulations will undoubtedly be the subject extensive sales,marketing and physician sampling efforts, particularly in view of the void created by the recent withdrawal of Vioxx@ and Bextra@,and the genericization of Ultram@,Ult ...
Dabigatran
Dabigatran

... 4. For atrial fibrillation (SPAF) the new oral anticoagulants appear to have a superior safety and efficacy profile. 5. Additional clinical trials are needed to determine the merit of these drugs beyond the ‘clinical trial’ populations, and to address ...
Diamide, Capsule
Diamide, Capsule

... not differentiate between chronic and acute indications or adults and children, the frequency Is estimated from all clinical trials with loperamide (acute and chronic), including trials in children ≤ 12 years (N=3683). b: See Warnings and Precautions. ...
Saving Lives- A Case for Stocking Narcan in our School Health Offices
Saving Lives- A Case for Stocking Narcan in our School Health Offices

... • Narcan knocks the opioid off the receptors in the brain and restores breathing. • Narcan acts quickly-within 1-3 minutes- to reverse the overdose. • Narcan is the only effective medication to reverse an opioid overdose ...
George M. Simpson by Thomas A. Ban
George M. Simpson by Thomas A. Ban

... GS: These other people were involved before me, but it was early on. We worked sort of independently and it was left up to you, what you did and how you did it. You could have said it was a government intervention to make it easier for the pharmaceutical houses to develop drugs. It was one way of se ...
Neural mechanisms underlying morphine withdrawal in addicted
Neural mechanisms underlying morphine withdrawal in addicted

... ability of maintaining a low constant level of isometric force (impaired motor control) (11,12). It was also demonstrated that morphine plays a crucial role in learning and memory (13). Passive avoidance learning, which is normally assessed by shuttle box (14), is affected by Morphine (15). Morphine ...
Preview the test
Preview the test

... 38) Certain benzodiazepines can be detected in urine screens with reasonable accuracy within only _____ hours after last use. a) 4 – 8 b) 12 – 16 c) 18 – 24 d) 48 – 72 39) The process of becoming addicted to psychoactive substances creates the ability for a wide variety of conditioned stimuli or __ ...
TESTOPEL - Endo Pharmaceuticals
TESTOPEL - Endo Pharmaceuticals

... the external genitalia of the female fetus. The virilization includes clitoromegaly, abnormal vaginal development, and fusion of genital folds to form a scrotal-like structure. The degree of masculinization is related to the amount of drug given and the age of the fetus, and is most likely to occur ...
Formulation and Evaluation of Almotriptan Malate Nasal Drops
Formulation and Evaluation of Almotriptan Malate Nasal Drops

... it most often resembles better the natural way of infections, self administration is easily done and therefore may gain a reasonable share within the next couple of years. ...
P4 - ADVANCED PHARMACY PRACTICE EXPERIENCE (APPE)  PRECEPTOR MANUAL
P4 - ADVANCED PHARMACY PRACTICE EXPERIENCE (APPE) PRECEPTOR MANUAL

... Preceptor Checklist: Before the Student Arrives The following are several items which you may want to check off before the rotation begins. You may also wish to provide some of this information to your student when he or she contacts you three to four weeks prior to the start of the rotation. 1. Rev ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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