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Neural Control of Movement: Motor Neuron Subtypes
Neural Control of Movement: Motor Neuron Subtypes

... inhibitory effect on motor programs. When this balance shifts toward increased inhibitory influence, it is manifested as trouble initiating movements in a Parkinson’s patient. In contrast, when the balance is shifted toward permissive function, it can be illustrated by the constant involuntary movem ...
Glucophage (metformin)
Glucophage (metformin)

... until the situation is clarified. Serum electrolytes, ketones, blood glucose and, if indicated, blood pH, lactate levels and even blood metformin levels may be useful. Once a patient is stabilized on any dose level of GLUCOPHAGE, gastrointestinal symptoms, which are common during initiation of thera ...
PHARMACY TECHNICIAN (PHT) 720 clock hours/ 36 weeks (Total
PHARMACY TECHNICIAN (PHT) 720 clock hours/ 36 weeks (Total

... This course begins with an overview of the anatomy of the heart and cardiac conduction system. It also includes conditions affecting the cardiovascular system, treatment, and medications. Students learn different classes of cardio medications, as well as their therapeutic effect and side effects. MO ...
Glycolysis as a target for the design of new anti
Glycolysis as a target for the design of new anti

... 367 million people at risk. New drugs are needed for leishmaniasis because the standard treatments can only be given parenterally, and the treatment courses are long, expensive, and may elicit severe adverse reactions. Moreover, key products such as antimonials are being compromised by drug resistan ...
Newer Antihistamines
Newer Antihistamines

... adversely in this population. Our objective was to evaluate the effects of these medications on central and peripheral histamine H1-receptors in children. Fifteen subjects with allergic rhinitis were tested before and 2-2.5 h after administration of diphenhydramine, hydroxyzine, or placebo in a doub ...
Comparison of antiepileptic drug prescribing in children in three
Comparison of antiepileptic drug prescribing in children in three

... type (conventional vs. newer AEDs). We also analyzed the frequency of AEDs prescribed for children and adolescents with an indication/diagnosis of epilepsy for all three databases together. Due to the absence of adolescent data in PEDIANET, prevalence of AED use for comparison in three countries was ...
Macrolids
Macrolids

... The prototype drug, erythromycin, which consists of two sugar moieties attached to a 14-atom lactone ring, was obtained in 1952 from Streptomyces erythreus. Clarithromycin and azithromycin are semisynthetic derivatives of erythromycin. ...
$doc.title

... FLC  has  a  dis6nct  clinical  and  histological  prognosis,  and  generally  occurs  in  young   individuals.    It  is  open  advanced  when  diagnosed  due  to  lack  of  symptoms.    Surgical   resec6ons  are  the  op6mal  treatmen ...
Healthcare Professional Guide
Healthcare Professional Guide

... should be considered in patients who are vulnerable to hypotension. Dysphagia has also been reported with use of XENAZINE; some cases of dysphagia were associated with aspiration pneumonia. • QT prolongation–related arrhythmias have been reported with use of XENAZINE. XENAZINE should not be used in ...
Benefits, adverse effects and drug interactionsof herbal
Benefits, adverse effects and drug interactionsof herbal

... Because the use of herbal therapies in the U.S. is escalating, it is essential to be aware of clinical and adverse effects, doses and potential drug-herb interactions. A consumer poll in 1998 indicated that one-third of respondents use botanical remedies, and nearly one in five taking prescription m ...
NORVIR® Capsules
NORVIR® Capsules

... been reported. Cases of anaphylaxis, toxic epidermal necrolysis (TEN), and Stevens-Johnson syndrome have also been reported. Discontinue treatment if severe reactions develop. 5.5 PR Interval Prolongation Ritonavir prolongs the PR interval in some patients. Post marketing cases of second or third de ...
DANGERS OF PHARMACEUTICAL SUBSTITUTES FOR NICOTINE
DANGERS OF PHARMACEUTICAL SUBSTITUTES FOR NICOTINE

... Bupropion (aka Wellbutrin, Zyban) have been approved for treatment of tobacco addiction. Used alone or in combination with other drugs it is claimed that they increase quit rates when compared to placebo, however research results tend to have been primarily provided by the drug manufacturers and the ...
bicalutamide-ga - Actavis think smart medicine
bicalutamide-ga - Actavis think smart medicine

... Combination therapy (with medical castration) in advanced prostate cancer. In a large, multicentre, controlled clinical trial, 813 patients with previously untreated advanced prostate cancer were randomised to receive Bicalutamide 50 mg once daily (404 patients) or flutamide 250 mg three times a day ...
Study of Sustained Blood Pressure-Lowering Effect of Azelnidipine
Study of Sustained Blood Pressure-Lowering Effect of Azelnidipine

Nembutal Sales Aid - Akorn Pharmaceuticals
Nembutal Sales Aid - Akorn Pharmaceuticals

Protease Nexin-1 and Thrombin Modulate Neuronal Ca*+
Protease Nexin-1 and Thrombin Modulate Neuronal Ca*+

... ertheless, prothrombin RNA is found in the CNS (Dihanich et al., 1991). Thrombin is known to alter neuronal and glial processes and disrupt their function (Gurwitz and Cunningham, 1988; Zum et al., 1988; Cavanaugh et al., 1990; Grabham et al., 1991; Suidan et al., 1992; Beecher et al., 1994). Thus, ...
Is GERD a Factor in Osteonecrosis of the Jaw? Evidence of
Is GERD a Factor in Osteonecrosis of the Jaw? Evidence of

Improving Blood Brain Barrier Permeation of Small
Improving Blood Brain Barrier Permeation of Small

Phase 1 study to evaluate the feasibility and efficacy
Phase 1 study to evaluate the feasibility and efficacy

... cytogenetic response (CCyR), overall survival (OS) at 7 years is 86% [5]. However, complete molecular remission (CMR) is only achieved in a minority of patients. Moreover, in a subset of patients the efficacy of imatinib is even not sufficient to induce complete cytogenetic responses and these patie ...
peptic ulcer
peptic ulcer

...  This can be considered under two headings: 1. The healing of an ulcer that has developed during NSAID or COX-2 inhibitor treatment; & 2. Strategies for preventing NSAID ulcers in patients who currently are ulcer free ...
(R)methadone versus racemic methadone: what is best for patient
(R)methadone versus racemic methadone: what is best for patient

... Methadone has been linked to cardiac arrhythmia. (R)-methadone appears to confer a lower risk of QT interval prolongation, resulting in debate over how best to treat patients needing this medication. A discussion of salient aspects of selecting therapy for opioid dependence and pain management and d ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... As a result of development of microbial resistance to multiple antibiotics, the antibiotic-free delivery systems for treatment of periodontal infections have been tried. Recent advances in nanotechnology introduce new therapeutic materials for periodontal regeneration. Nanoparticles are clusters of ...
Hyoscyamine Sulfate Tablets, USP
Hyoscyamine Sulfate Tablets, USP

... blurred vision, dilated pupils, hot dry skin, dizziness, dryness of the mouth, difficulty in swallowing, and CNS stimulation. Measures to be taken are immediate lavage of the stomach and injection of physostigmine 0.5 to 2 mg intravenously and repeated as necessary up to a total of 5 mg. Fever may b ...
Stimulants
Stimulants

... The severity of acute amphetamine and methylphenidate overdose depends on the amount ingested. An individual may experience a progression of the following symptoms from an acute overdose: restlessness, agitation, irritability, insomnia, hyperactivity, confusion, elevated blood pressure, rapid heart ...
Development, Estimation and Validation of Aripiprazole
Development, Estimation and Validation of Aripiprazole

... soluble in chloroform. The molecular formula is C23H27Cl2N302 and molecular weight is 448.39. Aripiprazole is a benzisoxazole derivative used as Antipsychotic. Aripiprazole acts as a D2 partial agonist. Aripiprazole is also a partial agonist at the 5HT1A receptor, and like the other atypical antipsy ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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