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متن کامل [DOC 196 kb] - Basic and Clinical Neuroscience
... of phenytoin. Phenytoin showed anticonvulsant effect by blocking the voltage-gated sodium channels (Kohl & Dannhardt, 2001). It has been reported that berberine reduce NMDA receptor binding and inhibit NMDA receptor channel current in brain. In addition, berberine protects neuronal cells from brain ...
... of phenytoin. Phenytoin showed anticonvulsant effect by blocking the voltage-gated sodium channels (Kohl & Dannhardt, 2001). It has been reported that berberine reduce NMDA receptor binding and inhibit NMDA receptor channel current in brain. In addition, berberine protects neuronal cells from brain ...
Fentanyl and Ativan In-Service
... Fast acting, Short duration, More potent than Morphine, ED’s increasing in use for all types of pain control even non-specific abdominal pain due to its short duration ( pt will unmask shortly ...
... Fast acting, Short duration, More potent than Morphine, ED’s increasing in use for all types of pain control even non-specific abdominal pain due to its short duration ( pt will unmask shortly ...
March 2012: Financial highlights of Financial highlights of the life
... (Jerusalem, Israel), together with Pontifax, Clal Biotechnology Industries, Professor Marta WeinstockRosin and others. Yissum has also announced that, together with the Technion Research and Development Foundation (TRDF), the technology transfer arm of the Technion Israel Institute of Technology, it ...
... (Jerusalem, Israel), together with Pontifax, Clal Biotechnology Industries, Professor Marta WeinstockRosin and others. Yissum has also announced that, together with the Technion Research and Development Foundation (TRDF), the technology transfer arm of the Technion Israel Institute of Technology, it ...
The Epidemiology of Alcohol and Drug Disorders
... of the International Statistical Classification of Diseases and Related Health Problems, 10th Revision enable diverse groups to arrive at common definitions of disorders by providing specific, generally observable criteria for each disorder. For substance use disorders, the Diagnostic and Statistica ...
... of the International Statistical Classification of Diseases and Related Health Problems, 10th Revision enable diverse groups to arrive at common definitions of disorders by providing specific, generally observable criteria for each disorder. For substance use disorders, the Diagnostic and Statistica ...
efficacy of Donepezil and Galantamine on retrograde amnesia
... dependent.15 Electroconvulsive shocks (ECS) down regulate muscarinic cholinergic receptors.2,3 This effect, therefore, may at least in part explain the cognitive deficits associated with the treatment. In the present study, Donepezil and Galantamine were studied for its eff ...
... dependent.15 Electroconvulsive shocks (ECS) down regulate muscarinic cholinergic receptors.2,3 This effect, therefore, may at least in part explain the cognitive deficits associated with the treatment. In the present study, Donepezil and Galantamine were studied for its eff ...
Association between KEGG Biological Pathways and Adverse Drug
... Main factors play an important role in the development ADRs, some of these are patient related, drug related or socially related factors. Understanding the different effects of these factors on ADRs enables healthcare professionals to select the most appropriate medication for an individual [3]. Adv ...
... Main factors play an important role in the development ADRs, some of these are patient related, drug related or socially related factors. Understanding the different effects of these factors on ADRs enables healthcare professionals to select the most appropriate medication for an individual [3]. Adv ...
for immediate release
... endocarditis caused by Streptococcus viridans or S. bovis. For endocarditis caused by enterococci (e.g., E. faecalis), vancomycin has been reported to be effective only in combination with an aminoglycoside. Vancomycin has been reported to be effective for the treatment of diphtheroid endocarditis. ...
... endocarditis caused by Streptococcus viridans or S. bovis. For endocarditis caused by enterococci (e.g., E. faecalis), vancomycin has been reported to be effective only in combination with an aminoglycoside. Vancomycin has been reported to be effective for the treatment of diphtheroid endocarditis. ...
Cytisine, the world`s oldest smoking cessation aid
... gradually, with a scheduled quit date at day 5, and ending with one to two tablets daily by days 21-25. Optimal doses and duration of treatment, however, are as yet undetermined because no human pharmacokinetic data have been published. ...
... gradually, with a scheduled quit date at day 5, and ending with one to two tablets daily by days 21-25. Optimal doses and duration of treatment, however, are as yet undetermined because no human pharmacokinetic data have been published. ...
DESIGN AND DEVELOPMENT OF MUCOADHESIVE BUCCAL DELIVERY FOR PANTOPRAZOLE
... Buccal drug delivery is an alternative route for the oral administration of drugs which undergo degradation in the gastrointestinal track or hepatic first pass metabolism. Buccal drug delivery offers a safer mode of drug delivery system and the dosage form can be removed in case of toxicity. Buccal ...
... Buccal drug delivery is an alternative route for the oral administration of drugs which undergo degradation in the gastrointestinal track or hepatic first pass metabolism. Buccal drug delivery offers a safer mode of drug delivery system and the dosage form can be removed in case of toxicity. Buccal ...
sodium lactate - Pfizer Injectables
... mutagenic potential or effects on fertility. Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Sodium Lactate Injection is administered to a nursing mother. Pregnancy Category C. Animal reprodu ...
... mutagenic potential or effects on fertility. Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Sodium Lactate Injection is administered to a nursing mother. Pregnancy Category C. Animal reprodu ...
the PDF - NEOMED Institute
... NEOMED’s Clinical Trial Application (CTA) to conduct a Phase II study for its product candidate NEO6860, a TrpV1 antagonist, for the treatment of osteoarthritis pain. The clinical trial will commence in the first quarter of 2016 and data are expected to be delivered the same year. The trial will enr ...
... NEOMED’s Clinical Trial Application (CTA) to conduct a Phase II study for its product candidate NEO6860, a TrpV1 antagonist, for the treatment of osteoarthritis pain. The clinical trial will commence in the first quarter of 2016 and data are expected to be delivered the same year. The trial will enr ...
BLOCK TIME MONDAY TUESDAY WEDNESDAY THURSDAY
... absent due to spinal or neurogenic shock, where only LMN signs are present. 3. For a radiculopathy, be able to predict: root level is involved based on the dermatomal distribution of radicular pain and pattern of muscle weakness and reflex loss. 4. Recognize: an extramedullary spinal cord lesion ...
... absent due to spinal or neurogenic shock, where only LMN signs are present. 3. For a radiculopathy, be able to predict: root level is involved based on the dermatomal distribution of radicular pain and pattern of muscle weakness and reflex loss. 4. Recognize: an extramedullary spinal cord lesion ...
ANNONA SQUAMOSA INDUCED GASTRIC ULCER IN ALBINO RATS. Full Proceeding Paper
... Peptic ulcer is a major health hazard both in terms of morbidity and mortality. It occurs due to imbalance between offensive versus impaired mucosal resistance. As an alternative to allopathic therapeutics, scientific research on plants used in traditional medicine is receiving growing interest as a ...
... Peptic ulcer is a major health hazard both in terms of morbidity and mortality. It occurs due to imbalance between offensive versus impaired mucosal resistance. As an alternative to allopathic therapeutics, scientific research on plants used in traditional medicine is receiving growing interest as a ...
Effects of amiodarone on thyroid function
... continued for 1 to 3 months (2). Side effects of prednisolone such as fluid retention which can precipitate cardiac failure must be anticipated and treated accordingly. About 50% of patients become euthyroid within 4 weeks of treatment. Periodic assessment of thyroid function is indicated in these p ...
... continued for 1 to 3 months (2). Side effects of prednisolone such as fluid retention which can precipitate cardiac failure must be anticipated and treated accordingly. About 50% of patients become euthyroid within 4 weeks of treatment. Periodic assessment of thyroid function is indicated in these p ...
Managing weight gain as a side effect of
... Weight gain is less likely with SSRIs when they are used for 6 months or less. There are diverse opinions about whether increases in body weight occur in patients using them for 1 year or longer. Paroxetine may be more likely than other SSRIs to cause weight gain during short-term or long-term treat ...
... Weight gain is less likely with SSRIs when they are used for 6 months or less. There are diverse opinions about whether increases in body weight occur in patients using them for 1 year or longer. Paroxetine may be more likely than other SSRIs to cause weight gain during short-term or long-term treat ...
Quantum of Effectiveness Evidence in FDA’s Approval of Orphan Drugs
... effective for their intended uses. FDA has for many decades acknowledged that there is a need for flexibility in applying its standard for approval. For example, one of FDA’s regulations states that: “FDA will approve an application after it determines that the drug meets the statutory standards for ...
... effective for their intended uses. FDA has for many decades acknowledged that there is a need for flexibility in applying its standard for approval. For example, one of FDA’s regulations states that: “FDA will approve an application after it determines that the drug meets the statutory standards for ...
In Vitro Metabolism of Haloperidol and Sila-Haloperidol
... (Bains and Tacke, 2003; Showell and Mills, 2003; Mills and Showell, 2004; Pooni and Showell, 2006). Silicon switches of marketed drugs have recently been reviewed (Pooni and Showell, 2006). The term carbon/silicon switch, also called sila-substitution, is used when a silicon analog of a known drug i ...
... (Bains and Tacke, 2003; Showell and Mills, 2003; Mills and Showell, 2004; Pooni and Showell, 2006). Silicon switches of marketed drugs have recently been reviewed (Pooni and Showell, 2006). The term carbon/silicon switch, also called sila-substitution, is used when a silicon analog of a known drug i ...
ANZCOR Guideline 11.5 – Medications in Adult Cardiac Arrest
... bolus of 0.5 mg/kg may be considered. It is not recommended to commence a lidocaine (lignocaine) infusion until return of spontaneous circulation. ...
... bolus of 0.5 mg/kg may be considered. It is not recommended to commence a lidocaine (lignocaine) infusion until return of spontaneous circulation. ...
Life Sciences, Vol. 32, pp. 971{-978 /_ Pergamo n Press
... following its repeated administration. LSD ingestion by humans produces a marked tolerance to the psychic effects of the drug after a single do_e of i00 micrograms, and a complete tolerance develops after 3-4 consecutive daily doses. This tolerance completely disappears within 4-5 days after drug wi ...
... following its repeated administration. LSD ingestion by humans produces a marked tolerance to the psychic effects of the drug after a single do_e of i00 micrograms, and a complete tolerance develops after 3-4 consecutive daily doses. This tolerance completely disappears within 4-5 days after drug wi ...
Abnormally persistent latent inhibition induced by
... typical and atypical APDs, limiting considerably the utility of the LI model as a tool for the detection of novel atypical APDs with potentially superior clinical efficacy. We have recently shown that typical and atypical APDs exert a differential effect on LI, which becomes manifested when these drugs ...
... typical and atypical APDs, limiting considerably the utility of the LI model as a tool for the detection of novel atypical APDs with potentially superior clinical efficacy. We have recently shown that typical and atypical APDs exert a differential effect on LI, which becomes manifested when these drugs ...
6.0 BRIEF RESUME OF THE INTENDED WORK: 6.1
... its validation which plays an important role in drug discovery and in the manufacture of biopharmaceuticals. Combination of both MS and HPLC methods are used to ensure the identity, purity and quality of drug substances. The effort in majority of analytical method development involves the validation ...
... its validation which plays an important role in drug discovery and in the manufacture of biopharmaceuticals. Combination of both MS and HPLC methods are used to ensure the identity, purity and quality of drug substances. The effort in majority of analytical method development involves the validation ...
09_Nonlinear pharmacokinetics
... (Cl) of most drugs are not expected to change when different doses are administered and/or when the drug is administered via different routes as a single dose or multiple doses • The kinetics of these drugs is described as linear, or dose-independent, pharmacokinetics and is characterized by the fir ...
... (Cl) of most drugs are not expected to change when different doses are administered and/or when the drug is administered via different routes as a single dose or multiple doses • The kinetics of these drugs is described as linear, or dose-independent, pharmacokinetics and is characterized by the fir ...