neuropathology of dopamine systems in schizophrenia
... dopaminergic neurons. This pigmentation is due to the presence of neuromelanin, which is a byproduct of the metabolism of dopamine, giving the SN its distinct dark color (Double et al., 2000; Zecca et al., 2008). Within this mesodiencephalic dopaminergic complex, the VTA is located medial to the SN, ...
... dopaminergic neurons. This pigmentation is due to the presence of neuromelanin, which is a byproduct of the metabolism of dopamine, giving the SN its distinct dark color (Double et al., 2000; Zecca et al., 2008). Within this mesodiencephalic dopaminergic complex, the VTA is located medial to the SN, ...
FNIRS Measures of Prefrontal Cortex Lateralization During Stuttered
... I am immensely grateful for the constant stream of support and encouragement from those who helped me navigate through the enlightening and often mystifying dissertation process. I am especially thankful for my Advisor, Dr. Barry Guitar for his warm and caring approach as a mentor and guide through ...
... I am immensely grateful for the constant stream of support and encouragement from those who helped me navigate through the enlightening and often mystifying dissertation process. I am especially thankful for my Advisor, Dr. Barry Guitar for his warm and caring approach as a mentor and guide through ...
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau
... 50,000 or 150,000g, and applied the supernatant to mouse primary cortical neurons. The uptake of tau was assessed by immunofluorescence labelling of intracellular human tau. After 24 h, human tau uptake was observed in neurons treated with 3,000 and 10,000g brain extracts, which presumably contained ...
... 50,000 or 150,000g, and applied the supernatant to mouse primary cortical neurons. The uptake of tau was assessed by immunofluorescence labelling of intracellular human tau. After 24 h, human tau uptake was observed in neurons treated with 3,000 and 10,000g brain extracts, which presumably contained ...
TRPV1 Receptors in the Central Nervous System: Potential for
... strong TRPV1-ir was detected in the Purkinje’s cell bodies, and in the initial axonal segment. Double immuno-fluorescence microscopy ([65]; Fig. 2) showed an extensive co-expression TRPV1 and CB1 receptors in various regions of the brain (around the cellular bodies of many pyramidal neurons througho ...
... strong TRPV1-ir was detected in the Purkinje’s cell bodies, and in the initial axonal segment. Double immuno-fluorescence microscopy ([65]; Fig. 2) showed an extensive co-expression TRPV1 and CB1 receptors in various regions of the brain (around the cellular bodies of many pyramidal neurons througho ...
frontal functions, connectivity and neural efficiency underpinning
... Neurophysiological fractionation of processes, to include possible inhibition, has been demonstrated between error detection processes and error evaluation processes and with the apparent inhibition or uncoupling of the latter, both of which are processes emanating from the anterior cingulate. These ...
... Neurophysiological fractionation of processes, to include possible inhibition, has been demonstrated between error detection processes and error evaluation processes and with the apparent inhibition or uncoupling of the latter, both of which are processes emanating from the anterior cingulate. These ...
Full-Text PDF
... Abstract: There is increasing evidence that prothrombin and its active derivative thrombin are expressed locally in the central nervous system. So far, little is known about the physiological and pathophysiological functions exerted by thrombin in the human brain. Extra-hepatic prothrombin expressio ...
... Abstract: There is increasing evidence that prothrombin and its active derivative thrombin are expressed locally in the central nervous system. So far, little is known about the physiological and pathophysiological functions exerted by thrombin in the human brain. Extra-hepatic prothrombin expressio ...
Decondensed DNA Release of Proteases Associated with Triggers
... Collection of transmigrated neutrophils To obtain transmigrated neutrophils in sufficient quantities to analyze their phenotypes, we collected neutrophils that had migrated across IL-1b– stimulated brain endothelium grown on larger six-well–format Transwell inserts (4.7 cm2 area/Transwell). For this ...
... Collection of transmigrated neutrophils To obtain transmigrated neutrophils in sufficient quantities to analyze their phenotypes, we collected neutrophils that had migrated across IL-1b– stimulated brain endothelium grown on larger six-well–format Transwell inserts (4.7 cm2 area/Transwell). For this ...
A neurotoxic regimen of MDMA suppresses behavioral, thermal and
... In addition to the long-term effects of MDMA on serotonergic neurons, MDMA also exerts effects that are thought to involve the acute release of 5-HT from axon terminals. Indeed, MDMA has been shown to increase the extracellular concentration of 5-HT, as well as dopamine, in several brain regions in ...
... In addition to the long-term effects of MDMA on serotonergic neurons, MDMA also exerts effects that are thought to involve the acute release of 5-HT from axon terminals. Indeed, MDMA has been shown to increase the extracellular concentration of 5-HT, as well as dopamine, in several brain regions in ...
Changes in Resting-State Functional Connectivity Following Delay
... Dr. Christine Larson or advice and valuable feedback. I would also like to thank the American Psychological Association for a dissertation research award that helped fund portions of this project. ...
... Dr. Christine Larson or advice and valuable feedback. I would also like to thank the American Psychological Association for a dissertation research award that helped fund portions of this project. ...
Circadian clocks in crustaceans: identified neuronal and cellular systems
... True endogenous rhythmicity, in general, persists free-running even in absence of entraining environmental cues. It is controlled by internal pacemakers, or clocks, which autonomously control cellular activity levels and thereby regulate physiological and behavioural events in an oscillatory pattern ...
... True endogenous rhythmicity, in general, persists free-running even in absence of entraining environmental cues. It is controlled by internal pacemakers, or clocks, which autonomously control cellular activity levels and thereby regulate physiological and behavioural events in an oscillatory pattern ...
What are the complications of spina bifida?
... nerves come through the open part of the spine. It causes nerve damage and other disabilities. Seventy to ninety percent of children with this condition also have too much fluid on their brains. This happens because fluid that protects the brain and spinal cord is unable to drain like it should. The ...
... nerves come through the open part of the spine. It causes nerve damage and other disabilities. Seventy to ninety percent of children with this condition also have too much fluid on their brains. This happens because fluid that protects the brain and spinal cord is unable to drain like it should. The ...
Document
... Formed by network of tight junctions Between endothelial cells of CNS capillaries Lipid-soluble compounds (O2, CO2), steroids, and prostaglandins diffuse into interstitial fluid of brain and spinal cord Astrocytes control blood–brain barrier by releasing chemicals that control permeability o ...
... Formed by network of tight junctions Between endothelial cells of CNS capillaries Lipid-soluble compounds (O2, CO2), steroids, and prostaglandins diffuse into interstitial fluid of brain and spinal cord Astrocytes control blood–brain barrier by releasing chemicals that control permeability o ...
The Brain and Cranial Nerves
... Highly branched, internal white matter of cerebellum Cerebellar nuclei: embedded in arbor vitae: – relay information to Purkinje cells Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
... Highly branched, internal white matter of cerebellum Cerebellar nuclei: embedded in arbor vitae: – relay information to Purkinje cells Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
Chronic Use and Cognitive Functioning and Mental Health
... regions during the task. The association between chronic cannabis use and decreased regional brain activity during an attention task was more pronounced among individuals who reported greater lifetime exposure to cannabis and an earlier onset of use. These differences in brain activity were diminish ...
... regions during the task. The association between chronic cannabis use and decreased regional brain activity during an attention task was more pronounced among individuals who reported greater lifetime exposure to cannabis and an earlier onset of use. These differences in brain activity were diminish ...
stimulant treatment history predicts frontal-striatal
... behavioral therapy, parent training) and/or pharmacological interventions. Treatment with stimulants such as methylphenidate and d-‐amphetamine is the pharmacological intervention of first choice in ADHD (NHS NICE guideline, 2008). Robust ac ...
... behavioral therapy, parent training) and/or pharmacological interventions. Treatment with stimulants such as methylphenidate and d-‐amphetamine is the pharmacological intervention of first choice in ADHD (NHS NICE guideline, 2008). Robust ac ...
Neural representation of olfactory mixtures in the honeybee
... Calcium-imaging data were analysed using custom-made software written in IDL (Research Systems Inc., CO, USA). Each odor stimulation recording corresponded to a three-dimensional matrix with two spatial dimensions (x, y pixels of the area of interest) and a temporal dimension (100 frames). Three ste ...
... Calcium-imaging data were analysed using custom-made software written in IDL (Research Systems Inc., CO, USA). Each odor stimulation recording corresponded to a three-dimensional matrix with two spatial dimensions (x, y pixels of the area of interest) and a temporal dimension (100 frames). Three ste ...
The natural endocast of Taung (Australopithecus africanus): Insights
... manuscript was completed? The reason, Dart explained, is that he was influenced by Earnest Hooton’s suggestion that discoverers should not be the ones to describe their specimens (Hooton, 1938). According to Dart: E. A. Hooton (’38) says: ‘‘The tendency toward aggrandizement of a rare or unique speci ...
... manuscript was completed? The reason, Dart explained, is that he was influenced by Earnest Hooton’s suggestion that discoverers should not be the ones to describe their specimens (Hooton, 1938). According to Dart: E. A. Hooton (’38) says: ‘‘The tendency toward aggrandizement of a rare or unique speci ...
MR Imaging of the Cranial Meninges with Emphasis on Contrast
... these patients was believed to be greater than that seen in group 1. However, the differences were occasionally subtle. In 24 of the 30 patients, the meninges were better detected more peripherally and laterally than would normally be expected, although no nodularity was seen. Longer continuous stre ...
... these patients was believed to be greater than that seen in group 1. However, the differences were occasionally subtle. In 24 of the 30 patients, the meninges were better detected more peripherally and laterally than would normally be expected, although no nodularity was seen. Longer continuous stre ...
On-line Optical Operant Conditioning of Cortical Activity
... Figure 1.2 Organization of motor cortex and related areas ............................................ 17 Figure 1.3 Operant conditioning with Skinner box ............................................................. 19 Figure ...
... Figure 1.2 Organization of motor cortex and related areas ............................................ 17 Figure 1.3 Operant conditioning with Skinner box ............................................................. 19 Figure ...
Altered Resting-State Functional Connectivity of
... in the animal literature (Pare et al, 1995), were recently clarified in healthy human adults with resting-state fMRI (Roy et al, 2009). The functional connectivity approach uses correlated neural activity between voxels to make inferences about the functional organization of the brain (Biswal et al, ...
... in the animal literature (Pare et al, 1995), were recently clarified in healthy human adults with resting-state fMRI (Roy et al, 2009). The functional connectivity approach uses correlated neural activity between voxels to make inferences about the functional organization of the brain (Biswal et al, ...
Complete Article - Journal of Morphological Science
... The vertebral arteries, which were branches of the subclavian arteries, ascended the neck via the transversal channel and penetrated the vertebral channel after passing through the alar and lateral vertebral foramena. On the ventral surface of the cervical spinal chord, these vessels crossed the for ...
... The vertebral arteries, which were branches of the subclavian arteries, ascended the neck via the transversal channel and penetrated the vertebral channel after passing through the alar and lateral vertebral foramena. On the ventral surface of the cervical spinal chord, these vessels crossed the for ...
Reuss 9..48
... GABA is a major transmitter of the SCN. Furthermore, there is multiple evidence that amino acid transmitters are of major importance for SCN function. GABA, thought to be the principal neurotransmitter in the SCN [Moore and Speh, 1993], is found in most if not all neurons, and the mRNA for its synth ...
... GABA is a major transmitter of the SCN. Furthermore, there is multiple evidence that amino acid transmitters are of major importance for SCN function. GABA, thought to be the principal neurotransmitter in the SCN [Moore and Speh, 1993], is found in most if not all neurons, and the mRNA for its synth ...
The Truth About Suboxone - Shore Behavioral Medicine
... Suboxone treatment is designed to control active withdrawal and then via a progressive dose reduction called a “taper” the patient is weaned off of Suboxone when their withdrawal is over and hopefully remains sober. Suboxone treatment is provided most often as an outpatient treatment by a Federally ...
... Suboxone treatment is designed to control active withdrawal and then via a progressive dose reduction called a “taper” the patient is weaned off of Suboxone when their withdrawal is over and hopefully remains sober. Suboxone treatment is provided most often as an outpatient treatment by a Federally ...
Mechanisms of Sleep Control - UCLA Integrative Center for
... Raphe—Locus ceruleus—Basal forebrain—Acetylcholine—Norepi-nephrine. ...
... Raphe—Locus ceruleus—Basal forebrain—Acetylcholine—Norepi-nephrine. ...
Structure and Function of the Brain Serotonin System
... and the evidence for both junctional and nonjunctional contacts. The anatomic distribution of the 5-HT receptor subtypes are reviewed. In addition there is evidence that the various serotonergic nuclei possess individual characteristics, such as the presence of cotransmitters, which may influence th ...
... and the evidence for both junctional and nonjunctional contacts. The anatomic distribution of the 5-HT receptor subtypes are reviewed. In addition there is evidence that the various serotonergic nuclei possess individual characteristics, such as the presence of cotransmitters, which may influence th ...