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Glucose-sensing neurons: Are they physiologically relevant?
Glucose-sensing neurons: Are they physiologically relevant?

... addition, differences in strain of rat and brain region may also be important variables. Microdialysis studies using the zero net flux method show that glucose levels vary with brain region and strain [30,31]. Even more interesting, brain glucose levels change with activity in a region-specific fash ...
Measuring Cortical Thickness - McConnell Brain Imaging Centre
Measuring Cortical Thickness - McConnell Brain Imaging Centre

... this approach finds the shortest line from the cortical surface to the grey and white matter boundary - though the direction which that line could take may be constrained. The use of this straight-line method was initially implemented in the study of post-mortem specimen, where the investigator woul ...
as a PDF
as a PDF

... both the intracellular and extracellular fluid compartments. These stimuli are sensed by two kinds of receptors: osmoreceptor-Na⫹ receptors and volume or pressure receptors. This information is conveyed to specific areas of the central nervous system responsible for an integrated response, which dep ...
L-Dopa and Brain Serotonin System Dysfunction
L-Dopa and Brain Serotonin System Dysfunction

... Another consequence of this “off-target” effect is that L-dopa can become toxic to 5-HT systems. One mechanism of 5-HT neurotoxicity appears to be related to oxidative stress produced by L-dopa-induced supraphysiologic concentrations of dopamine. Dopamine has long been known to be a potent oxidant [ ...
Neural representation of olfactory mixtures in the honeybee
Neural representation of olfactory mixtures in the honeybee

... (ii) Overall activity maps. As we could recognize the same set of 24 glomeruli in 10 different bees, we could build a physiological atlas of mixture activity, as was done for many odors by Galizia et al. (1999a). For this, the response amplitudes of each glomerulus (5 · 5 pixels, see above) for each ...
Hikosaka O - lsr
Hikosaka O - lsr

... tissue that includes the habenula is transplanted into these rats the normal sleep pattern and atonia are restored15,17. Second, the firing of habenula neurons shows circadian rhythmicity 18, even in slice preparations19. Third, neural activity of the LHb or the MHb increases markedly during drug-in ...
Dopamine: the rewarding years
Dopamine: the rewarding years

... 1957 to its present-day position as a major neurotransmitter in the brain. This neurotransmitter is involved in the control of movement and Parkinson’s disease, the neurobiology and symptoms of schizophrenia and attention deficit hyperactivity disorder. It is also considered an essential element in ...
More on the evolution of imitation
More on the evolution of imitation

... surprised psychologists. They showed that infants could imitate prior to the learning experiences, indicating an innate mapping between observation and execution. In an early study, imitation of facial gestures was documented in twoto three-week-old infants (Meltzoff & Moore, 1977). A first question ...
Document
Document

... BIN1 is the second most significant Alzheimer’s disease (AD) risk factor gene identified through genome-wide association studies. BIN1 is an adaptor protein that can bind to several proteins including c-Myc, clathrin, adaptor protein-2 and dynamin. BIN1 is widely expressed in the brain and periphera ...
NIH Public Access
NIH Public Access

... measured across species with relatively simple autonomic or behavioral responses that may even occur non-consciously in humans (Bechara and others 1995; Ohman and Soares 1998), PTSD is a uniquely human disorder that involves explicit re-experience of the traumatic event, subjective distress, and com ...
the inferior colliculus of the rat: quantitative
the inferior colliculus of the rat: quantitative

... colliculus (IC), which is a major relay en route to the medial geniculate body (MGB; Malmierca et al., 2002; Malmierca and Merchán, 2004). Afferent projections to the IC are both excitatory and inhibitory (Oliver, 1984a, 1987; Shneiderman and Henkel, 1987; Saint Marie et al., 1989; Saint Marie and B ...
Cerebral hemisphere regulation of motivated
Cerebral hemisphere regulation of motivated

... divisions — somatic, autonomic, and neuroendocrine. Turning first to the organization of neural inputs to the motor system, Cajal pointed out long ago that sensory systems generally have a dual projection within the central nervous system. One branch goes directly to the motor system, and the other ...
(2000). Cerebral hemisphere regulation of motivated behavior.
(2000). Cerebral hemisphere regulation of motivated behavior.

... divisions — somatic, autonomic, and neuroendocrine. Turning first to the organization of neural inputs to the motor system, Cajal pointed out long ago that sensory systems generally have a dual projection within the central nervous system. One branch goes directly to the motor system, and the other ...
The thalamus as a putative biomarker in neurodegenerative disorders
The thalamus as a putative biomarker in neurodegenerative disorders

... During development the primitive forebrain gives rise to the telencephalon (or end-brain), which has as its derivatives the cerebral cortex, striatum, amygdala, and associated structures, and the diencephalon (or between-brain), which gives rise primarily to the thalamus and hypothalamus. It is like ...
DOES ISCHEMIA CAUSE ACUTE NEURONAL DAMAGE BY CONVERTING THE NA /K
DOES ISCHEMIA CAUSE ACUTE NEURONAL DAMAGE BY CONVERTING THE NA /K

... al., 1981; Woodruff et al., 2011). The penumbra is the prime target of stroke therapeutics because it is potentially salvageable after the onset of stroke (Dirnagl et al., 1999). This may be achieved following timely reperfusion within 6-8 hours (Kaufmann et al., 1999). The brain injury and neurolog ...
Serotonin Modulates Developmental Microglia
Serotonin Modulates Developmental Microglia

... Interestingly, eye-specific segregation of retinal projections in the thalamus also depends on an appropriate serotonin (5-Hydroxytryptamine, 5-HT) level. Segregation of ipsilateral and contralateral regions in dLGN does not occur properly in mice lacking the gene encoding monoamine oxidase A (MAOA) ...
Chapter 1
Chapter 1

... • He also found that by 8 months, babies can distinguish a picture of a wooden toy they were allowed to feel, but not see, from pictures of other toys. • This coincides with the development of the hippocampus. ©2005 McGraw-Hill Ryerson Ltd. ...
Topic - We can offer most test bank and solution manual you need.
Topic - We can offer most test bank and solution manual you need.

... c) dendrite b) soma d) cell membrane 3. Which of the following neurotransmitters functions as a common inhibitory neurotransmitter in the brain? a) serotonin c) acetylcholine b) norepinephrine d) GABA 4. Which part of the nervous system takes the information received from the senses, makes sense out ...
Full-Text PDF
Full-Text PDF

... implicit level and another on an explicit level [28–32]. Whereas the cerebellum has been associated with information processing on an implicit level in other functional domains [33–35], it has been described as being involved in the implicit and explicit components of the emotional domain [36,37]. I ...
the phase-space dynamics of systems of spiking neurons
the phase-space dynamics of systems of spiking neurons

... Science remained out of favor until the beginning of the Renaissance. In 1543 Andreas Vesalius published De Humani Corporis Fabrica that helped correct numerous misconceptions about the human anatomy that had prevailed for fifteen hundred years. The 1641 publication of René Descartes’ Meditationes ...
Generation of Theta and Gamma Rhythms in the Hippocampus
Generation of Theta and Gamma Rhythms in the Hippocampus

... LEUNG, L. S. Generation of theta and gamma rhythms in the hippocampus. NEUROSCI BIOBEHAV REV 22(2), 275–290, 1998.—In the behaving rat, theta rhythm was dominant during walking and rapid-eye-movement sleep, while irregular slow activity predominated during immobility and slow-wave sleep. Oscillatory ...
FNIRS Measures of Prefrontal Cortex Lateralization During Stuttered
FNIRS Measures of Prefrontal Cortex Lateralization During Stuttered

... of speech production in AWS when speaking fluently and disfluently as measured by greater bilateral change in PFC HbO relative to TS. AWS laterality did not differ from TS during everyday conversation and did not significantly change when using fluencyenhancing strategies, which was counter to the h ...
Eye fields in the frontal lobes of primates
Eye fields in the frontal lobes of primates

... commonly referred to as the frontal eye field ŽFEF.. This review documents the similarities and differences between these eye fields. Although the DMFC and FEF are both active during the execution of saccadic and smooth pursuit eye movements, the FEF is more dedicated to these functions. Lesions of ...
Review Spectrin and calpain
Review Spectrin and calpain

... from aged human individuals either with or without associated age-related diseases. For that reason calcium-dependent processes which seem to be convergence points among various degenerative mechanisms undoubtly play ...
Full PDF
Full PDF

... inputs; the ratio of excitatory to inhibitory synaptic contacts is ⬃10:1, which is unprecedented in the CNS (71). This pattern of synaptic organization, which results in noise assuming the characteristics of signal, allows hypocretinergic neurons to be easily activated, leading to rapid arousal (71) ...
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Neurophilosophy

Neurophilosophy or philosophy of neuroscience is the interdisciplinary study of neuroscience and philosophy that explores the relevance of neuroscientific studies to the arguments traditionally categorized as philosophy of mind. The philosophy of neuroscience attempts to clarify neuroscientific methods and results using the conceptual rigor and methods of philosophy of science.While the issue of brain-mind is still open for debate, from the perspective of neurophilosophy, an understanding of the philosophical applications of neuroscience discoveries is nevertheless relevant. Even if neuroscience eventually found that there is no causal relationship between brain and mind, the mind would still remain associated with the brain, some would argue an epiphenomenon, and as such neuroscience would still be relevant for the philosophy of the mind. At the other end of the spectrum, if neuroscience will eventually demonstrate a perfect overlap between brain and mind phenomena, neuroscience would become indispensable for the study of the mind. Clearly, regardless of the status of the brain-mind debate, the study of neuroscience is relevant for philosophy.
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