• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Encyclopedia of Cell Biology Brochure
Encyclopedia of Cell Biology Brochure

... abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, t ...
The Excitement of Biochemical Engineering
The Excitement of Biochemical Engineering

... One of the earliest challenges we faced was to address a potential threat to the large scale processing of proteins which would have made the preparation of enough material for patients extremely difficult. These are very complex molecules as the simulated image of one of the smaller catalytic prote ...
Regulation of Heat-Shock Response in Bacteria
Regulation of Heat-Shock Response in Bacteria

... concluded that this response is a stress response and not only a heat-shock response. The group of proteins involved in the heat-shock response, called heatshock proteins, includes chaperons, proteases, and regulatory factors. Among these the best studied genes and proteins are the two major chapero ...
Introduction to bioinformatics I617
Introduction to bioinformatics I617

... Rooted and Unrooted Trees In the unrooted tree the position of the root (“common ancestor”) is unknown. Otherwise, they are like rooted trees ...
identification of tendon and ligament specific genes
identification of tendon and ligament specific genes

... into muscle, bone and fat. These cells should also be able to differentiate into tendon or ligament fibroblasts, but the conditions necessary for this differentiation are not yet known. Also, there are few definitive markers available to verify that the stem cells have differentiated into tendon or ...
Transcription - My Teacher Pages
Transcription - My Teacher Pages

... Once the entire gene has been transcribed, the RNA strand detaches completely from the DNA. Exactly how RNA polymerase recognizes the end of a gene is very complicated but we will discuss as it reaching a Stop signal. ...
Introduction to molecular biology
Introduction to molecular biology

... Transcriptome: ...
WHAT IS BIOENGINEERING?
WHAT IS BIOENGINEERING?

... 1830: Proteins, the building blocks of cells, are discovered 1833: The nucleus of the cell is discovered 1855: The E. coli bacterium is discovered ...
Chapter 5 Gases
Chapter 5 Gases

... 10.1 What Is Gene Control? • A typical cell in your body uses only about 10 percent of its genes at one time – Some genes affect structural features and metabolic pathways and are expressed in many cell types – Others genes are expressed only by certain subsets of cells (e.g., globin in RBCs) – Con ...
NOGG_Instruction
NOGG_Instruction

... Background Information Noggin is a secreted polypeptide which binds and inactivates ...
gene - LICH
gene - LICH

... come up with a bibliography for a particular sequence. • However, they do not provide easy access to sequence data when your query deals with broader issues related to a gene or function. • The second-generation nucleotide-sequence databases have adopted a more gene-centric perspective. • all the se ...
DNA Replication, RNA Molecules and Transcription
DNA Replication, RNA Molecules and Transcription

... A transcription reaction requires a DNA molecule to serve as template for transcription with a promoter (and, in vivo, transcription factors) to indicate where to begin transcribing and which strand to transcribe. Transcription reactions also require an RNA polymerase that recognizes the promoter on ...
Plant cell Animal cell
Plant cell Animal cell

... where light energy from the sun which is trapped by chlorophyll is used to split water (H20) into hydrogen and oxygen and releases energy as ATP (high energy molecule). Oxygen is given off as a by product. ATP and hydrogen are needed for the second enzyme controlled stage called carbon fixation wher ...
Cell Biology Lecture Notes
Cell Biology Lecture Notes

... Quantitative biochemistry [A]=[T] and [G]=[C] Explain heredity DNA replication process is semiconservative RNA serves as an informational carrier intermediate between DNA and protein Prokaryotes Eukaryotes ...
Notes Biotechnology Chpt 20
Notes Biotechnology Chpt 20

... gene now and later mtDNA) • Restriction Enzyme Digest – use of enzymes to cut DNA (plasmid mapping and taster gene) • Gel electrophoresis – used to separate different sizes of DNA fragments (plasmid mapping, taster gene, and later mtDNA) • Sequencing – determine exact base sequence of a section of D ...
Biofab_(2)
Biofab_(2)

... enabling novel structures and invention ...
Adding Protein Context to the Human Protein-Protein
Adding Protein Context to the Human Protein-Protein

... all interactions. On the other hand, the 159 interactions associated with the (depth 3) GO category ‘ribonucleoprotein complex assembly’ have an average confidence score of 0.754. We observed a similar tendency for more specific MeSH terms to have a higher experimental reliability. To demonstrate th ...
nuclear envelope - Lectures For UG-5
nuclear envelope - Lectures For UG-5

... Selective transportation of regulatory factors and energy molecules through nuclear pores. ...
Gene Section AFF3 (lymphoid nuclear protein related to AF4)
Gene Section AFF3 (lymphoid nuclear protein related to AF4)

... Coding sequence of LAF4 compared to AF4 and site of fusion. Schematic representation of MLL, LAF4, AF4, and the putative MLL-LAF4 fusion protein. Domains in MLL are shaded: MT, DNA methyltransferase homology region; TRX, Drosophila trithorax homology. The percentage of amino acid homology between co ...
Slide 1
Slide 1

... Promoter regions – sequence involved in the control of expression of a given gene, site where RNA polymerase binds Regulatory regions – sequence involved in the control of expression of a given gene, usually involves interaction with another molecule ...
Call for Papers – WABI 2016
Call for Papers – WABI 2016

... molecular biology, that are founded on sound models, that are computationally efficient, and that have been implemented and tested in simulations and on real datasets. The goal is to present recent research results, including significant work-in-progress, and to identify and explore directions of fu ...
sc-101769 (Page 1) - Santa Cruz Biotechnology, Inc.
sc-101769 (Page 1) - Santa Cruz Biotechnology, Inc.

... The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p5 ...
Path Seminar_Amarni_Luke
Path Seminar_Amarni_Luke

... frequently translocated or mutated in AML, 25 % of patients do not have a disruption in known AML genes. We hypothesise that in cases where no mutation or translocation is found in the coding sequence of RUNX1, there may be mutations in non-coding regulatory sequences that affect gene expression. Th ...
Phenotypic and dynamical transitions in model genetic networks
Phenotypic and dynamical transitions in model genetic networks

... Tam and Behringer, 1997), formation of invertebrate and vertebrate appendages (Ng et al., 1999; Panganiban et al., 1997), and segmentation (Davis and Patel, 1999). It can be concluded from such work that most developmental processes in present-day organisms are complicated and highly integrated. But ...
Introduction to high-‐throughput experiments and data analysis
Introduction to high-‐throughput experiments and data analysis

... • Many  different  types:  mRNA,  tRNA,  rRNA,   miRNA,  snoRNA,  etc.   ...
< 1 ... 173 174 175 176 177 178 179 180 181 ... 320 >

Gene regulatory network



A gene regulatory network or genetic regulatory network (GRN) is a collection of regulators thatinteract with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins.The regulator can be DNA, RNA, protein and their complex. The interaction can be direct or indirect (through their transcribed RNA or translated protein).In general, each mRNA molecule goes on to make a specific protein (or set of proteins). In some cases this protein will be structural, and will accumulate at the cell membrane or within the cell to give it particular structural properties. In other cases the protein will be an enzyme, i.e., a micro-machine that catalyses a certain reaction, such as the breakdown of a food source or toxin. Some proteins though serve only to activate other genes, and these are the transcription factors that are the main players in regulatory networks or cascades. By binding to the promoter region at the start of other genes they turn them on, initiating the production of another protein, and so on. Some transcription factors are inhibitory.In single-celled organisms, regulatory networks respond to the external environment, optimising the cell at a given time for survival in this environment. Thus a yeast cell, finding itself in a sugar solution, will turn on genes to make enzymes that process the sugar to alcohol. This process, which we associate with wine-making, is how the yeast cell makes its living, gaining energy to multiply, which under normal circumstances would enhance its survival prospects.In multicellular animals the same principle has been put in the service of gene cascades that control body-shape. Each time a cell divides, two cells result which, although they contain the same genome in full, can differ in which genes are turned on and making proteins. Sometimes a 'self-sustaining feedback loop' ensures that a cell maintains its identity and passes it on. Less understood is the mechanism of epigenetics by which chromatin modification may provide cellular memory by blocking or allowing transcription. A major feature of multicellular animals is the use of morphogen gradients, which in effect provide a positioning system that tells a cell where in the body it is, and hence what sort of cell to become. A gene that is turned on in one cell may make a product that leaves the cell and diffuses through adjacent cells, entering them and turning on genes only when it is present above a certain threshold level. These cells are thus induced into a new fate, and may even generate other morphogens that signal back to the original cell. Over longer distances morphogens may use the active process of signal transduction. Such signalling controls embryogenesis, the building of a body plan from scratch through a series of sequential steps. They also control and maintain adult bodies through feedback processes, and the loss of such feedback because of a mutation can be responsible for the cell proliferation that is seen in cancer. In parallel with this process of building structure, the gene cascade turns on genes that make structural proteins that give each cell the physical properties it needs.It has been suggested that, because biological molecular interactions are intrinsically stochastic, gene networks are the result of cellular processes and not their cause (i.e. cellular Darwinism). However, recent experimental evidence has favored the attractor view of cell fates.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report