Interaction of Graphene Oxide with Proteins and
... between proteins and side groups of graphene oxide also support surface adhesion. The hydrophobic interaction between GO and proteins strongly depends on electron density and geometry of protein molecule. Lee et al. [2] demonstrated that the lower electron density of the low-molecular weight heparin ...
... between proteins and side groups of graphene oxide also support surface adhesion. The hydrophobic interaction between GO and proteins strongly depends on electron density and geometry of protein molecule. Lee et al. [2] demonstrated that the lower electron density of the low-molecular weight heparin ...
Interpro - European Bioinformatics Institute
... • Given a set of uncharacterised sequences, we usually want to know: – what are these proteins; to what family do they belong? – what is their function; how can we explain this in structural terms? ...
... • Given a set of uncharacterised sequences, we usually want to know: – what are these proteins; to what family do they belong? – what is their function; how can we explain this in structural terms? ...
Macromolecules Biological Molecules Macromolecules
... Proteins: Environmental conditions affect protein structure Some Conditions can not break covalent bonds, but can upset the weaker noncovalent interactions that determine secondary and tertiary structure, may affect a protein's shape and thus its function Denaturation Couses: Increases in tempe ...
... Proteins: Environmental conditions affect protein structure Some Conditions can not break covalent bonds, but can upset the weaker noncovalent interactions that determine secondary and tertiary structure, may affect a protein's shape and thus its function Denaturation Couses: Increases in tempe ...
Characterizing the Secreted Proteome of Mycobacterium
... dotted lines mark the approximate peak intensity on the 116 and 117 signals which corresponds to a 1:1 peak area ratio after normalization. Both of these proteins contain N-terminal secretion signals, which means secretion should not be dependent on the ESX-1 system, but this data indicate that ther ...
... dotted lines mark the approximate peak intensity on the 116 and 117 signals which corresponds to a 1:1 peak area ratio after normalization. Both of these proteins contain N-terminal secretion signals, which means secretion should not be dependent on the ESX-1 system, but this data indicate that ther ...
Michael Z. Lin and Lei Wang
... The first and most extensively used system for specific labeling of a peptide by functionalized small molecules is the tetracysteine-biarsenical system. The basic components, rationally designed by Griffin and colleagues (24), are peptide tags with the consensus sequence CCXXCC and chemical probes, ...
... The first and most extensively used system for specific labeling of a peptide by functionalized small molecules is the tetracysteine-biarsenical system. The basic components, rationally designed by Griffin and colleagues (24), are peptide tags with the consensus sequence CCXXCC and chemical probes, ...
Assembly and maintenance of the sarcomere night and day
... Titin is a central player in the assembly process. It is a multifunctional protein containing multiple binding sites for structural and signalling proteins, as well as an inherent kinase domain, and also serves as a molecular spring.16 The N-terminus of titin spans the Z-disc and contains several sm ...
... Titin is a central player in the assembly process. It is a multifunctional protein containing multiple binding sites for structural and signalling proteins, as well as an inherent kinase domain, and also serves as a molecular spring.16 The N-terminus of titin spans the Z-disc and contains several sm ...
Systematic Analysis of Arabidopsis Organelles
... protein from its subcellular location? and (2) What properties do the major cellular compartments have and share with other compartments? GeneMerge method compares the GO annotations of genes in a subset of genes under investigation (e.g. genes that are induced in expression under a certain conditio ...
... protein from its subcellular location? and (2) What properties do the major cellular compartments have and share with other compartments? GeneMerge method compares the GO annotations of genes in a subset of genes under investigation (e.g. genes that are induced in expression under a certain conditio ...
mRNA surveillance: the perfect persist
... although many of these observations may be explained by mutation of splicing enhancers (Liu et al., 2001). In addition, human Upf proteins interact with mRNAs associated with nuclear poly-A- and cap-binding proteins (Ishigaki et al., 2001). However, both of these proteins shuttle between the nucleus ...
... although many of these observations may be explained by mutation of splicing enhancers (Liu et al., 2001). In addition, human Upf proteins interact with mRNAs associated with nuclear poly-A- and cap-binding proteins (Ishigaki et al., 2001). However, both of these proteins shuttle between the nucleus ...
Study of the arginine repressor in different organisms
... ArgR proteins play a multifunctional role in the bacterial cell. They inhibit biosynthetic promoters and are involved in activation of several catabolic pathways. The arginine repressor of Streptomyces clavuligerus participates in regulation of clavulanic acid production. The Escherichia coli repres ...
... ArgR proteins play a multifunctional role in the bacterial cell. They inhibit biosynthetic promoters and are involved in activation of several catabolic pathways. The arginine repressor of Streptomyces clavuligerus participates in regulation of clavulanic acid production. The Escherichia coli repres ...
Isolation and Characterization of Foaming Proteins of
... suggests that isohumulones can combine with the higher and medium molecular weight fractions. Changes of Foaming Proteins during Malting and Brewing Because foaming proteins formed immunoprecipitates with antimalt serum, and to a lesser extent with antibarley and antiyeast sera, as shown in Fig. 10, ...
... suggests that isohumulones can combine with the higher and medium molecular weight fractions. Changes of Foaming Proteins during Malting and Brewing Because foaming proteins formed immunoprecipitates with antimalt serum, and to a lesser extent with antibarley and antiyeast sera, as shown in Fig. 10, ...
Concept 3.1 Nucleic Acids Are Informational
... • 1st: energy can be transferred and transformed, but it cannot be created or destroyed (energy of the universe is constant) • 2nd: every energy transfer of transformation makes the universe more disordered (every process increases the entropy of the universe) • Entropy: quantitative measure of diso ...
... • 1st: energy can be transferred and transformed, but it cannot be created or destroyed (energy of the universe is constant) • 2nd: every energy transfer of transformation makes the universe more disordered (every process increases the entropy of the universe) • Entropy: quantitative measure of diso ...
GPS-Lipid Manual - CSS-Palm
... geranylgeranylation is performed by protein geranylgeranyltransferase type I (GGTase-I) (12,13). However, in case of Rab proteins, the geranylgeranyltransferase type II (GGTase-II) which recognized a C-terminal CC/CXC motif is found to catalyze the geranylgeranylation process (10,14). In addition to ...
... geranylgeranylation is performed by protein geranylgeranyltransferase type I (GGTase-I) (12,13). However, in case of Rab proteins, the geranylgeranyltransferase type II (GGTase-II) which recognized a C-terminal CC/CXC motif is found to catalyze the geranylgeranylation process (10,14). In addition to ...
ID helix-loop-helix proteins - Journal of Cell Science
... phosphorylation of the tumour suppressor protein pRB (and related ‘pocket proteins’, p107 and p130), resulting in its dissociation from members of the E2F family of transcriptional regulators. Free E2F-DP1 (E2F) transcriptional complexes then activate the expression of genes required for progression ...
... phosphorylation of the tumour suppressor protein pRB (and related ‘pocket proteins’, p107 and p130), resulting in its dissociation from members of the E2F family of transcriptional regulators. Free E2F-DP1 (E2F) transcriptional complexes then activate the expression of genes required for progression ...
Supplementary materials
... protein lengths. The closest sequence match was extracted for each protein. The results of the three methods were combined and manually adjusted taking into account genome neighborhood information. 3. Identification of gene duplications: Alignments of the Shewanella proteins were generated using Dar ...
... protein lengths. The closest sequence match was extracted for each protein. The results of the three methods were combined and manually adjusted taking into account genome neighborhood information. 3. Identification of gene duplications: Alignments of the Shewanella proteins were generated using Dar ...
Importance of main-chain hydrophobic free energy to the stability of
... of 56 globular proteins from 16 different families. In this work, we construct a non-redundant data set of 23 families of thermophilic protein and its mesophilic counterpart from the previous studies [19–21]. These families span an entire spectrum, containing proteins from moderately thermophilic or ...
... of 56 globular proteins from 16 different families. In this work, we construct a non-redundant data set of 23 families of thermophilic protein and its mesophilic counterpart from the previous studies [19–21]. These families span an entire spectrum, containing proteins from moderately thermophilic or ...
Expression and Purification of Functional Ligand
... expression and purification of the ligand-binding domain of T1R taste receptors, which are constituents of the sweet and umami taste receptors. These class C GPCRs contain a large extracellular N-terminal domain (NTD) that is the site of interaction with most ligands and that is amenable to expressio ...
... expression and purification of the ligand-binding domain of T1R taste receptors, which are constituents of the sweet and umami taste receptors. These class C GPCRs contain a large extracellular N-terminal domain (NTD) that is the site of interaction with most ligands and that is amenable to expressio ...
Identification and Developmental Expression of a Novel Low
... the XNK3 cDNA clone, an antibody (anti-XNIF) was generated against a synthetic peptide (Peptide Technologies, Washington, DC) from the C-terminal domain of the predicted sequence of the Xenopus neuronal intermediate filament (XNIF) protein (amino acid sequence KTSKPGDQEKI). The synthetic peptide was ...
... the XNK3 cDNA clone, an antibody (anti-XNIF) was generated against a synthetic peptide (Peptide Technologies, Washington, DC) from the C-terminal domain of the predicted sequence of the Xenopus neuronal intermediate filament (XNIF) protein (amino acid sequence KTSKPGDQEKI). The synthetic peptide was ...
video slide - Independent School District 196
... ribosomal subunit 1 A small ribosomal subunit binds to a molecule of mRNA. In a prokaryotic cell, the mRNA binding site on this subunit recognizes a specific nucleotide sequence on the mRNA just upstream of the start codon. An initiator tRNA, with the anticodon UAC, base-pairs with the start codon, ...
... ribosomal subunit 1 A small ribosomal subunit binds to a molecule of mRNA. In a prokaryotic cell, the mRNA binding site on this subunit recognizes a specific nucleotide sequence on the mRNA just upstream of the start codon. An initiator tRNA, with the anticodon UAC, base-pairs with the start codon, ...
the rna code comes into focus
... (m1A) in mouse and human cell lines and tissues8,9. Using different approaches to prevent m1A from interfering with reverse transcription, the two teams showed that m1A, which was discovered in total RNA in the early 1960s, is present on mRNA at the position at which the translation machinery initia ...
... (m1A) in mouse and human cell lines and tissues8,9. Using different approaches to prevent m1A from interfering with reverse transcription, the two teams showed that m1A, which was discovered in total RNA in the early 1960s, is present on mRNA at the position at which the translation machinery initia ...
Chapter 12: Protein structure, stability and folding
... Biochemistry as a discipline is primarily concerned with molecular mechanisms of biological processes. These days, the starting point is often 3-dimensional structure, usually obtained from X-ray crystallography. Genomic sequencing and structural genomics projects continue to provide a wealth of inf ...
... Biochemistry as a discipline is primarily concerned with molecular mechanisms of biological processes. These days, the starting point is often 3-dimensional structure, usually obtained from X-ray crystallography. Genomic sequencing and structural genomics projects continue to provide a wealth of inf ...
Transcription
... regions contain the coding information for specific proteins and hence correspond to genes. That is, the process of transcription copies the coding sequence for one or more adjacent genes into RNA. DNA that is copied into RNA is known as a transcription unit. Transcription units originate from a spe ...
... regions contain the coding information for specific proteins and hence correspond to genes. That is, the process of transcription copies the coding sequence for one or more adjacent genes into RNA. DNA that is copied into RNA is known as a transcription unit. Transcription units originate from a spe ...
Inquiry into Life Twelfth Edition
... • Splicing that occurs in all eukaryotic species is called cis-splicing because it involves 2 or more exons that exist together in the same gene • Alternatively, trans-splicing has exons that are not part of the same gene at all, may not even be on the same chromosome ...
... • Splicing that occurs in all eukaryotic species is called cis-splicing because it involves 2 or more exons that exist together in the same gene • Alternatively, trans-splicing has exons that are not part of the same gene at all, may not even be on the same chromosome ...
Chlamydia pneumoniae CdsQ functions as a multi
... the injectisome and play a role in the selection and delivery of effector proteins through the injectisome [23, 24]. A few T3S ATPases have been characterized, including EscN from E. coli [25, 26], YscN from Yersinia [27, 28], and InvC from Salmonella [29]. The ATPase of C. pneumoniae is enzymatical ...
... the injectisome and play a role in the selection and delivery of effector proteins through the injectisome [23, 24]. A few T3S ATPases have been characterized, including EscN from E. coli [25, 26], YscN from Yersinia [27, 28], and InvC from Salmonella [29]. The ATPase of C. pneumoniae is enzymatical ...
Investigation 1: Examining RNA-Seq data
... Gaps (introns) – Figure 3 is a screen shot of the genome browser with gaps circled. Note that there are 2 gaps in females, and 2 gaps in males. The first gap in females looks a little strange because it doesn't have clean boundaries, suggesting a mixed population of processed transcripts. Exons – Br ...
... Gaps (introns) – Figure 3 is a screen shot of the genome browser with gaps circled. Note that there are 2 gaps in females, and 2 gaps in males. The first gap in females looks a little strange because it doesn't have clean boundaries, suggesting a mixed population of processed transcripts. Exons – Br ...
SR protein
SR proteins are a conserved family of proteins involved in RNA splicing. SR proteins are named because they contain a protein domain with long repeats of serine and arginine amino acid residues, whose standard abbreviations are ""S"" and ""R"" respectively. SR proteins are 50-300 amino acids in length and composed of two domains, the RNA recognition motif (RRM) region and the RS binding domain. SR proteins are more commonly found in the nucleus than the cytoplasm, but several SR proteins are known to shuttle between the nucleus and the cytoplasm.SR proteins were discovered in the 1990s in Drosophila and in amphibian oocytes, and later in humans. In general, metazoans appear to have SR proteins and unicellular organisms lack SR proteins.SR proteins are important in constitutive and alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by preferentially selecting different splice sites on the pre-mRNA strands to create multiple mRNA transcripts from one pre-mRNA transcript. Once splicing is complete the SR protein may or may not remain attached to help shuttle the mRNA strand out of the nucleus. As RNA Polymerase II is transcribing DNA into RNA, SR proteins attach to newly made pre-mRNA to prevent the pre-mRNA from binding to the coding DNA strand to increase genome stabilization. Topoisomerase I and SR proteins also interact to increase genome stabilization. SR proteins can control the concentrations of specific mRNA that is successfully translated into protein by selecting for nonsense-mediated decay codons during alternative splicing. SR proteins can alternatively splice NMD codons into its own mRNA transcript to auto-regulate the concentration of SR proteins. Through the mTOR pathway and interactions with polyribosomes, SR proteins can increase translation of mRNA.Ataxia telangiectasia, neurofibromatosis type 1, several cancers, HIV-1, and spinal muscular atrophy have all been linked to alternative splicing by SR proteins.