Monstrous Mutations - Campbell County Schools
... A ________________is a _________________ that exchanges one ____________ for another (i.e., a change in a single “chemical letter” such as switching an A to a G). Such a substitution could: 1. Change a codon to one that encodes a different amino acid and cause a small change in the protein produced. ...
... A ________________is a _________________ that exchanges one ____________ for another (i.e., a change in a single “chemical letter” such as switching an A to a G). Such a substitution could: 1. Change a codon to one that encodes a different amino acid and cause a small change in the protein produced. ...
Human Genome Project The Human Genome Project
... genes, or to genes in mice or yeast or fruit flies, possible detrimental mutations, interactions with other genes, body tissues in which this gene is activated, diseases associated with this gene or other datatypes. Further, deeper understanding of the disease processes at the level of molecular bio ...
... genes, or to genes in mice or yeast or fruit flies, possible detrimental mutations, interactions with other genes, body tissues in which this gene is activated, diseases associated with this gene or other datatypes. Further, deeper understanding of the disease processes at the level of molecular bio ...
Intrastrand Self-complementary Sequences in Bacillus subtilis DNA
... 60 % of the HA HI1 DNA was resistant to S 1 nuclease, whereas thermal denaturation profiles (data not shown) indicated that only 25 % of HA HI1 DNA forms helical regions, suggesting that the resistant DNA contains single-stranded, presumably unpaired, loop regions. Thus the self-complementary sequen ...
... 60 % of the HA HI1 DNA was resistant to S 1 nuclease, whereas thermal denaturation profiles (data not shown) indicated that only 25 % of HA HI1 DNA forms helical regions, suggesting that the resistant DNA contains single-stranded, presumably unpaired, loop regions. Thus the self-complementary sequen ...
BMC Evolutionary Biology D- and L-lactate dehydrogenases during invertebrate evolution
... is immunologically more similar to LDH-C in teleost fish than to LDH-A or LDH-B [14-16]. Our phylogenetic analyses of L-LDH isozymes are consistent with the general view of a major gene duplication event near the origin of vertebrates. Both NJ and MP phylogenies suggest that the vertebrate isozymes ...
... is immunologically more similar to LDH-C in teleost fish than to LDH-A or LDH-B [14-16]. Our phylogenetic analyses of L-LDH isozymes are consistent with the general view of a major gene duplication event near the origin of vertebrates. Both NJ and MP phylogenies suggest that the vertebrate isozymes ...
Accuracy of protein flexibility predictions
... order of improvement was noticed also in the other three methods. Many of the highest peaks were already filtered away when the three N- and C-terminal residues of each protein were not included in the calculation of prediction parameters. This was done because the ends are known to be exceptionally ...
... order of improvement was noticed also in the other three methods. Many of the highest peaks were already filtered away when the three N- and C-terminal residues of each protein were not included in the calculation of prediction parameters. This was done because the ends are known to be exceptionally ...
Cold-Shock Response in Microorganisms
... temperature, and the cellular response to this is termed the “cold-shock response."Earth’s biosphere ranges in temperature from above 100 °C to below 0 °C. However, the bulk of the biosphere is cold (e.g., most of the ocean, alpine regions, and natural environments exposed to the winter season, as w ...
... temperature, and the cellular response to this is termed the “cold-shock response."Earth’s biosphere ranges in temperature from above 100 °C to below 0 °C. However, the bulk of the biosphere is cold (e.g., most of the ocean, alpine regions, and natural environments exposed to the winter season, as w ...
A MODEL FOR THE PROTEOLYTIC REGULATION OF
... synthesis. It is believed that the protease FtsH regulates LpxC activity via cleavage. It is also suspected that the activity of FtsH is regulated by a metabolite produced by the LPS pathway; however, it is not known which one. In order to investigate these mechanisms, we obtained kinetic parameters ...
... synthesis. It is believed that the protease FtsH regulates LpxC activity via cleavage. It is also suspected that the activity of FtsH is regulated by a metabolite produced by the LPS pathway; however, it is not known which one. In order to investigate these mechanisms, we obtained kinetic parameters ...
Identification of a putative flexible loop in Arabidopsis glutathione
... rotational freedom in the region, and should cause loss of function in a sequence where conformational flexibility is essential. Similar substitutions of valine in the larger flexible loop of the E. coli GSH synthetase also resulted in loss of enzyme activity [9,11]. The ability to align these seque ...
... rotational freedom in the region, and should cause loss of function in a sequence where conformational flexibility is essential. Similar substitutions of valine in the larger flexible loop of the E. coli GSH synthetase also resulted in loss of enzyme activity [9,11]. The ability to align these seque ...
In vitro biological activities of Douglas fir essential oil in
... products, research regarding their biological effects on human skin cells is scarce. Here, we studied the biological activity of a commercially available Douglas fir (Pseudotsuga menziesii) essential oil (DEO) in a human dermal fibroblast model of chronic inflammation and fibrosis induced by stimula ...
... products, research regarding their biological effects on human skin cells is scarce. Here, we studied the biological activity of a commercially available Douglas fir (Pseudotsuga menziesii) essential oil (DEO) in a human dermal fibroblast model of chronic inflammation and fibrosis induced by stimula ...
Lipid profiling and transcriptomic analysis reveals a functional
... pharmacological doses of E2 in humans inhibits GH-regulated endocrine (e.g., IGF-I) and metabolic (e.g., lipid oxidation, protein synthesis) effects [22,23] but these effects are attenuated when E2 is administered transdermally, suggesting that liver is the major target of regulatory cross-talk betw ...
... pharmacological doses of E2 in humans inhibits GH-regulated endocrine (e.g., IGF-I) and metabolic (e.g., lipid oxidation, protein synthesis) effects [22,23] but these effects are attenuated when E2 is administered transdermally, suggesting that liver is the major target of regulatory cross-talk betw ...
SnRK1 Isoforms AKIN10 and AKIN11 Are
... that respond rapidly and often nonspecifically to Pi deficiency and the late genes that alter the morphology, physiology, or metabolism of plants upon prolonged stress. These late genes generally increase the acquisition of Pi or promote the efficient use of Pi within the plant (Vance et al., 2003). ...
... that respond rapidly and often nonspecifically to Pi deficiency and the late genes that alter the morphology, physiology, or metabolism of plants upon prolonged stress. These late genes generally increase the acquisition of Pi or promote the efficient use of Pi within the plant (Vance et al., 2003). ...
A siderophore biosynthesis gene cluster from the fish
... mass iron-chelating molecules that can remove iron from host iron-binding proteins (Crosa, 1989) and then enter the cell through outer-membrane receptor proteins. Many siderophores are small peptides synthesized by nonribosomal peptide synthetases (NRPSs), which are multimodular enzymes that produce ...
... mass iron-chelating molecules that can remove iron from host iron-binding proteins (Crosa, 1989) and then enter the cell through outer-membrane receptor proteins. Many siderophores are small peptides synthesized by nonribosomal peptide synthetases (NRPSs), which are multimodular enzymes that produce ...
Ultramer® Oligonucleotides - Integrated DNA Technologies
... such as direct or inverted repeats and homopolymeric runs. It is difficult to avoid deletions and insertions introduced by the PCR-based methods if there exist no conveniently located regions of unique sequence that allow overlaps to be placed at the necessary positions. Ultramer Oligonucleotides, h ...
... such as direct or inverted repeats and homopolymeric runs. It is difficult to avoid deletions and insertions introduced by the PCR-based methods if there exist no conveniently located regions of unique sequence that allow overlaps to be placed at the necessary positions. Ultramer Oligonucleotides, h ...
Sec14p-like proteins regulate phosphoinositide homoeostasis and
... Sec9p t-SNARE (target membrane soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) function Stt4p and Mss4p reside in the yeast plasma membrane [22]. This raises the possibility that SFH proteins modulate exocytic and/or endocytic events at the plasma membrane. To investig ...
... Sec9p t-SNARE (target membrane soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) function Stt4p and Mss4p reside in the yeast plasma membrane [22]. This raises the possibility that SFH proteins modulate exocytic and/or endocytic events at the plasma membrane. To investig ...
Metabolic rate depression in animals
... production by central pathways of fuel catabolism. All cells have mechanisms for increasing ATP production when energy demand is high and for scaling back production when energy demand declines. Conversely, situations that limit ATP production will quickly affect the rates of ATP-utilizing processes. ...
... production by central pathways of fuel catabolism. All cells have mechanisms for increasing ATP production when energy demand is high and for scaling back production when energy demand declines. Conversely, situations that limit ATP production will quickly affect the rates of ATP-utilizing processes. ...
Codrea_Biochem_07 - The University of Texas at Austin
... modifications such as acetylation and glycosylation. Another common way in which proteins perform complex chemistry reactions is by coordinating with metal ions and sequestering them within the active site. One drawback is that many post-translational modifications, such as phosphorylation, are not ...
... modifications such as acetylation and glycosylation. Another common way in which proteins perform complex chemistry reactions is by coordinating with metal ions and sequestering them within the active site. One drawback is that many post-translational modifications, such as phosphorylation, are not ...
Pupko_pairwise
... E-values of 10-4 and lower indicate a significant homology. E-values between 10-4 and 10-2 should be checked (similar domains, maybe non-homologous). E-values between 10-2 and 1 do not indicate a good homology ...
... E-values of 10-4 and lower indicate a significant homology. E-values between 10-4 and 10-2 should be checked (similar domains, maybe non-homologous). E-values between 10-2 and 1 do not indicate a good homology ...
Cytochrome P450 3A4: The Impossible Protein
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
... this situation the drugs will not be oxidized in the same way that they would be if there were only one bound to the protein. This makes it difficult to administer more than one drug at once because of the possible effects that occur due to 3A4. In addition to having this binding property, 3A4 is t ...
02 Cholesterol Metabolism2012-03-18 01:50617 KB
... Most important animal steroid Maintains membrane fluidity Insulating effect on nerve fibres Cholesterol is the parent molecule for – Bile acids and bile salts – Steroid hormones – Vitamin D3 ...
... Most important animal steroid Maintains membrane fluidity Insulating effect on nerve fibres Cholesterol is the parent molecule for – Bile acids and bile salts – Steroid hormones – Vitamin D3 ...
Chloroplast phosphoglycerate kinase from Euglena gracilis
... almost identical proteins of 423 amino acids that differ in only one residue. Asp422 of the second PGK protein (and also of the identical C-terminal fragment of the first unit) was replaced by Asn in the third PGK protein at the 3¢ end. At the nucleotide level sequence identity of the PGK segments is ...
... almost identical proteins of 423 amino acids that differ in only one residue. Asp422 of the second PGK protein (and also of the identical C-terminal fragment of the first unit) was replaced by Asn in the third PGK protein at the 3¢ end. At the nucleotide level sequence identity of the PGK segments is ...
Evolution of Cellular Data Processing
... Prokaryotes are capable of switching their genes on and off in a specific and signal-controlled mode in order to adapt to the actual conditions of the biotope. As far as the molecular mechanism is concerned, there is no fundamental difference between prokaryotic and eukaryotic gene transcription. In ...
... Prokaryotes are capable of switching their genes on and off in a specific and signal-controlled mode in order to adapt to the actual conditions of the biotope. As far as the molecular mechanism is concerned, there is no fundamental difference between prokaryotic and eukaryotic gene transcription. In ...
CytoSure™ Genomic DNA Labelling Kits
... This product is provided under an agreement between Agilent Technologies, Inc. and OGT. The manufacture, use, sale or import of this product may be subject to one or more of U.S. patents, pending applications, and corresponding international equivalents, owned by Agilent Technologies, Inc. The purch ...
... This product is provided under an agreement between Agilent Technologies, Inc. and OGT. The manufacture, use, sale or import of this product may be subject to one or more of U.S. patents, pending applications, and corresponding international equivalents, owned by Agilent Technologies, Inc. The purch ...