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Post-transcriptional gene control
Post-transcriptional gene control

... b) methylation of 2’ OH groups at specific sites c) converting of uridine to pseudouridine ...
Genetic Engineering Notes
Genetic Engineering Notes

... o A carrier molecule called a _____________must be used to deliver the therapeutic gene to the patient's target cells. o The most common vector is a ___________that has been genetically altered to carry normal human DNA. o Ex: To reverse disease caused by genetic damage, researchers isolate normal D ...
Lecture 1: Molecular Biology
Lecture 1: Molecular Biology

... primer base-paired to the template strand, a DNA polymerase adds nucleotides to the free hydroxyl group at the 3’ end of the primer. • DNA replication requires assembly of many proteins (at least 30) at a growing replication fork: helicases to unwind, primases to prime, ligases to ligate (join), top ...
FUNCTIONAL DIVERGENCE TOPIC 4: Evolution of new genes and
FUNCTIONAL DIVERGENCE TOPIC 4: Evolution of new genes and

... Assume that an exon will be inserted into an intron of another gene; its fitness effects will be impacted by its effect on the reading frame. Hence, exon shuffling is limited by the phase of the introns. If an intron is PHASE 0, it lies between two intact codons. If a foreign exon is inserted within ...
DNA replication
DNA replication

... or, DNA was introduced externally?!? ...
structure and function of genome
structure and function of genome

... chromosomal DNA which is capable of replicating independently from the chromosomal DNA. In many cases, it is circular and double-stranded. Plasmids usually occur naturally in bacteria, Its size varies from 1.5 to 15 kb. ...
DNA Structure
DNA Structure

... rows of bases with free-ends, on which new complementary strands can form Template strand-The original strand of DNA Daughter strand-The strand of DNA which is created during DNA replication Semi-conservative Replication- the method by which DNA is replicated in all known cells - produces two copies ...
Document
Document

Methods S1.
Methods S1.

... databases were used to identify potential miRNA targets. In order to have more accurate prediction results, we chose the targets genes that were predicted in two out of three databases and were conserved in other species. ...
Name: Genetics Week 7 Review for Test 1. Figure 1 The diagram
Name: Genetics Week 7 Review for Test 1. Figure 1 The diagram

... The diagrams represent portions of the genes that code for wing structure in two organisms of the same species. Gene 1 was taken from the cells of a female with normal wings, and gene 2 was taken from the cells of a female with abnormal wings. The abnormal wing structure was most likely due to 1. a ...
Central Dogma of Molecular Biology
Central Dogma of Molecular Biology

... Your DNA, or deoxyribonucleic acid, contains the genes that determine who you are. How can this organic molecule control your characteristics? DNA contains instructions for all the proteins your body makes. Proteins, in turn, determine the structure and function of all your cells. What determines a ...
HOW TO GET TO WHERE YOU WANT TO BE
HOW TO GET TO WHERE YOU WANT TO BE

... 
methods.

Star@ng
in
second
year
we
teach
how
to
grow,
characterize,
 
and

iden@fy

bacteria
and
extract
their
DNA.
In
our
third
and
fourth
year
 
we
have
intensive
courses
that
combine
molecular,
microbiological
 
and
biochemical
methods
into
compelling
modules
that
use
an
array
 
of
techniques
t ...
Genetics and DNA Replication Notes
Genetics and DNA Replication Notes

... o Translation – the t-RNA “translates” the script from the m-RNA into the chain of amino acids in the cytoplasm, at the site of the ribosomes in the cytoplasm; codon/set of 3 bases of m-RNA matches anticodon/set of 3 of t-RNA. The anti-codon carries the correct amino acid to be added to the protein ...
Slide 1
Slide 1

... Codes for a protein… Which then carries out a job ...
genome
genome

... answered easily. Planners suggest developing a human genome database analogous to model organism databases with links to phenotypic information. Also needed are databases and analytical tools for the expanding body of gene expression and function data, for modeling complex biological networks and in ...
1. ELONGATION
1. ELONGATION

... Machinery.The machinery depicted here encompasses over 85 polypeptides in 10 (sub) complexes: core RNA polymerase II (RNAPII) consists of 12 subunits; TFIIH, 9 subunits; TFIIE, 2 subunits; TFIIF, 3 subunits; TFIIB, 1 subunit, TFIID, 14 subunits; core SRB/mediator, more than 16 subunits; Swi/Snf comp ...
transcription factor
transcription factor

... Promoter Genes of operon ...
genetic_testD_key
genetic_testD_key

... When making traditional vaccines scientist weaken or kill a harmful virus or bacteria and inject it into the body so that the person’s white blood cells will react to the surface proteins of the harmful bacteria or virus and build antibodies against it. The problem is that if the pathogen is not wea ...
Unit 3 Concepts Study Guide
Unit 3 Concepts Study Guide

Lay summary of the final report Dec 1997
Lay summary of the final report Dec 1997

... Retinoblastoma (Rb) is a childhood cancer which develops in the retina of the eye. Over 90% of affected children survive if the disease is detected at an early stage, although most loose at least one eye. In 15% of cases there is a previous family history of disease. Members of these families can of ...
Description
Description

... differences or polymorphisms (Greek; poly=many , morphos= form) resulting from mutation that alter the site of restriction fragmentation catalyzed by a restriction enzyme.  They affect the restriction enzymatic cleavage sites, DNA fragments of different sizes will result these variation are called ...
Recitation 4 - MIT OpenCourseWare
Recitation 4 - MIT OpenCourseWare

... Meiosis has two divisions; meiosis 1 looks different from mitosis, but meiosis II looks similar to mitosis. The result of meiosis is the production of haploid gamete cells such as eggs or sperm, each of which has half the number of chromosomes as a diploid somatic cell. Recombination and crossing ov ...
S1 Text
S1 Text

... Blastomyces could have a considerably more closed chromatin structure than the GC-rich DNA of the same genome. The chromatin difference, i.e., compartmentalized organization of genes, could then have given those genes that are programmed to be used only under specific, rare conditions an additional ...
Exam 2
Exam 2

... After the DNA binding domain binds a GC box, the Gln rich domain interacts with DNA to enhance transcription. The DNA binding domain has at least two Cys residues. The DNA binding domain likely has Asp residues to interact with the DNA phosphate backbone. Sp1 binds the minor groove of DNA. Sp1 disto ...
DNA Replication - Texas Tech University
DNA Replication - Texas Tech University

... Transcribe 5.8S, 18S and 28S genes S = Svedberg units, sedimentation coefficient related to centrifugation The bigger the number the bigger the molecule ...
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Silencer (genetics)

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