Amine-functionalized boehmite nanoparticle-supported
... The Mo(CO)6 and VOSO4·H2O complexes were used to sup‐ port on BNPs or AFBNPs (Scheme 1). For this purpose, Mo(CO)6 (0.276 g, 1.05 mmol) was activated under ultraviolet light in tetrahydrofuran (THF, 20.0 mL) for 30 min. This acti‐ vated molybdenum complex was then added to ...
... The Mo(CO)6 and VOSO4·H2O complexes were used to sup‐ port on BNPs or AFBNPs (Scheme 1). For this purpose, Mo(CO)6 (0.276 g, 1.05 mmol) was activated under ultraviolet light in tetrahydrofuran (THF, 20.0 mL) for 30 min. This acti‐ vated molybdenum complex was then added to ...
Aromatic Compounds
... Rings: The Friedel-Crafts Reaction Alkylation • The introduction of an alkyl group onto the benzene ring • Called the Friedel-Crafts reaction after its discoverers • Among the most useful electrophilic aromatic substitution ...
... Rings: The Friedel-Crafts Reaction Alkylation • The introduction of an alkyl group onto the benzene ring • Called the Friedel-Crafts reaction after its discoverers • Among the most useful electrophilic aromatic substitution ...
22.4: Acidity of Phenols.
... 22.3: Physical Properties (please read). Like other alcohols the OH group of phenols cab participate in hydrogen bonding with other phenol molecules and to water. 22.4: Acidity of Phenols. Phenols are more acidic than aliphatic alcohols ...
... 22.3: Physical Properties (please read). Like other alcohols the OH group of phenols cab participate in hydrogen bonding with other phenol molecules and to water. 22.4: Acidity of Phenols. Phenols are more acidic than aliphatic alcohols ...
Organic Chemistry
... • the carbon skeleton: how can we put it together. Our only method to date for forming new a C-C bond is the alkylation of alkyne anions (Section 7.5) • the functional groups: what are they, how can they be used in forming the carbon-skeleton of the target molecule, and how can they be changed to gi ...
... • the carbon skeleton: how can we put it together. Our only method to date for forming new a C-C bond is the alkylation of alkyne anions (Section 7.5) • the functional groups: what are they, how can they be used in forming the carbon-skeleton of the target molecule, and how can they be changed to gi ...
Learning Guide for Chapter 16
... What does the starting material look like before the H is removed to make the alkoxide? What is this functional group called? ...
... What does the starting material look like before the H is removed to make the alkoxide? What is this functional group called? ...
α-cleavage of alkenes
... - side chain cleavage - long chain McLafferty alcohols: α-cleavage next to C-O bond M-1 peak (loss of H) M+ peak strong for aromatic alcohols (phenols) Ethers: ...
... - side chain cleavage - long chain McLafferty alcohols: α-cleavage next to C-O bond M-1 peak (loss of H) M+ peak strong for aromatic alcohols (phenols) Ethers: ...
Neuman Chapter - Department of Chemistry
... They also show that the relative amounts of elimination and substitution products vary significantly depending on the structure of the substrate. Nucleophile versus Base. When ethoxide ion displaces a leaving group in a SN2 reaction, we call it a nucleophile. When ethoxide ion removes a β-H in an E2 ...
... They also show that the relative amounts of elimination and substitution products vary significantly depending on the structure of the substrate. Nucleophile versus Base. When ethoxide ion displaces a leaving group in a SN2 reaction, we call it a nucleophile. When ethoxide ion removes a β-H in an E2 ...
ether - HCC Southeast Commons
... are prepared by the sulfuric acid-catalyzed dehydration procedure? What product(s) would you expect if ethanol and 1-propanol were allowed to react together? In what ratio would the products be formed if the two alcohols were of equal reactivity? ...
... are prepared by the sulfuric acid-catalyzed dehydration procedure? What product(s) would you expect if ethanol and 1-propanol were allowed to react together? In what ratio would the products be formed if the two alcohols were of equal reactivity? ...
Electrophilic Selenium Catalysis with Electrophilic N
... Functionalization of alkenes is a perpetual goal in organic synthesis. One of the attractive routes to elaborate the carbon–carbon double bond of alkenes is through electrophilic selenium reagent-promoted selenofunctionalization. In this context, several electrophilic organoselenium reagents ArSeX ( ...
... Functionalization of alkenes is a perpetual goal in organic synthesis. One of the attractive routes to elaborate the carbon–carbon double bond of alkenes is through electrophilic selenium reagent-promoted selenofunctionalization. In this context, several electrophilic organoselenium reagents ArSeX ( ...
Alcohols, Thiols, and Ethers Ch#5
... The longest chain contains six carbon atoms, but it does not contain the carbon bonded to the hydroxyl group. The longest chain containing the carbon bonded to the —OH group is the one outlined by the green box, containing five carbon atoms. This chain is numbered from right to left in order to give ...
... The longest chain contains six carbon atoms, but it does not contain the carbon bonded to the hydroxyl group. The longest chain containing the carbon bonded to the —OH group is the one outlined by the green box, containing five carbon atoms. This chain is numbered from right to left in order to give ...
Chapter 23 SG5e
... nitration reaction. This leads to the desired product with the hydroxy group in the 3 position. Step (1) Oxidation at a benzylic carbon (Section 20.6A) can be brought about using chromic acid to give benzoic acid. Step (2) Nitration of the aromatic ring using HNO3 in H2SO4. The meta-directing carbox ...
... nitration reaction. This leads to the desired product with the hydroxy group in the 3 position. Step (1) Oxidation at a benzylic carbon (Section 20.6A) can be brought about using chromic acid to give benzoic acid. Step (2) Nitration of the aromatic ring using HNO3 in H2SO4. The meta-directing carbox ...
Amines and amides
... This reaction involves breaking the C-N bond at the carbonyl carbon. a. acid hydrolysis: forms “ammonium” ion and carboxylic acid b. alkaline hydrolysis: forms carboxylate ion and amine Condensation Polymers As we have seen –COOH (and COCl) react with amines to form 2ry amides A Condensation reactio ...
... This reaction involves breaking the C-N bond at the carbonyl carbon. a. acid hydrolysis: forms “ammonium” ion and carboxylic acid b. alkaline hydrolysis: forms carboxylate ion and amine Condensation Polymers As we have seen –COOH (and COCl) react with amines to form 2ry amides A Condensation reactio ...
9: Formation of Alkenes and Alkynes. Elimination Reactions
... They also show that the relative amounts of elimination and substitution products vary significantly depending on the structure of the substrate. Nucleophile versus Base. When ethoxide ion displaces a leaving group in a SN2 reaction, we call it a nucleophile. When ethoxide ion removes a β-H in an E2 ...
... They also show that the relative amounts of elimination and substitution products vary significantly depending on the structure of the substrate. Nucleophile versus Base. When ethoxide ion displaces a leaving group in a SN2 reaction, we call it a nucleophile. When ethoxide ion removes a β-H in an E2 ...
Microsoft Word
... racemic and the chiral pyrrolidine 21a was obtained after resolution. Also two approaches are known for 20a based on SN2 displacement reaction and chiral resolution from tartaric acid. Herein we represent a short stereoselective and general approach for the synthesis of both 20a and 21a starting fro ...
... racemic and the chiral pyrrolidine 21a was obtained after resolution. Also two approaches are known for 20a based on SN2 displacement reaction and chiral resolution from tartaric acid. Herein we represent a short stereoselective and general approach for the synthesis of both 20a and 21a starting fro ...
View/Open - AURA - Alfred University
... mediate the Ritter reaction under mild conditions and it may now be possible to use unprotected, acid-sensitive functional groups. In an attempt to determine the scope of the PEDOT-mediated Ritter reaction, a number of alcohols were reacted with acetonitrile. Given that these reactions used acetonit ...
... mediate the Ritter reaction under mild conditions and it may now be possible to use unprotected, acid-sensitive functional groups. In an attempt to determine the scope of the PEDOT-mediated Ritter reaction, a number of alcohols were reacted with acetonitrile. Given that these reactions used acetonit ...
Modified polyacrylamide-supported chlorochromate as a
... During the past years, there have been several important advances in the field of organic synthesis; the use of polymer-supported reagents is one of them.1 Polymeric reagents can be defined as functionalized polymers used in stoichiometric amounts in one-step processes to transform low-molecular-wei ...
... During the past years, there have been several important advances in the field of organic synthesis; the use of polymer-supported reagents is one of them.1 Polymeric reagents can be defined as functionalized polymers used in stoichiometric amounts in one-step processes to transform low-molecular-wei ...
Aldehydes, Ketones and Carboxylic Acids
... You have already studied most of the methods used in the synthesis of aldehydes and ketones in the previous lesson. Let us now refresh them. 1. Oxidation of Primary and Secondary Alcohols From the last lesson, you know that primary alcohols can be oxidised to aldehydes and secondary alcohols can be ...
... You have already studied most of the methods used in the synthesis of aldehydes and ketones in the previous lesson. Let us now refresh them. 1. Oxidation of Primary and Secondary Alcohols From the last lesson, you know that primary alcohols can be oxidised to aldehydes and secondary alcohols can be ...
Presentation
... 5) Reduction of aldehyde, RCHO with sodium and ethanol gives (A) 1° alcohol (B) 2° alcohol (C) 3° alcohol (D) alkane ...
... 5) Reduction of aldehyde, RCHO with sodium and ethanol gives (A) 1° alcohol (B) 2° alcohol (C) 3° alcohol (D) alkane ...
Chapter 22 Summary - McGraw Hill Higher Education
... Alkylation of ammonia (Section 22.7) Ammonia can act as a nucleophile toward primary and some secondary alkyl halides to give primary alkylamines. Yields tend to be modest because the primary amine is itself a nucleophile and undergoes alkylation. Alkylation of ammonia can lead to a mixture containi ...
... Alkylation of ammonia (Section 22.7) Ammonia can act as a nucleophile toward primary and some secondary alkyl halides to give primary alkylamines. Yields tend to be modest because the primary amine is itself a nucleophile and undergoes alkylation. Alkylation of ammonia can lead to a mixture containi ...
Alcohols, Aldehydes, and Ketones
... of a primary alcohol at the aldehyde stage in order to prevent the aldehyde from being oxidized further to the carboxylic acid. One way to do this is to remove the aldehyde as soon as it is formed by distilling it from the reaction mixture. Reactions such as these can be used to measure alcohol cont ...
... of a primary alcohol at the aldehyde stage in order to prevent the aldehyde from being oxidized further to the carboxylic acid. One way to do this is to remove the aldehyde as soon as it is formed by distilling it from the reaction mixture. Reactions such as these can be used to measure alcohol cont ...
Chapter 20 Amines - FIU Faculty Websites
... • 10 Amines are named using either systematic or common names. • To assign a systematic name, find the longest continuous chain bonded to the amine nitrogen, and change the –e ending of the parent alkane to the suffix –amine. Then use the usual rules of nomenclature to number the chain and name the ...
... • 10 Amines are named using either systematic or common names. • To assign a systematic name, find the longest continuous chain bonded to the amine nitrogen, and change the –e ending of the parent alkane to the suffix –amine. Then use the usual rules of nomenclature to number the chain and name the ...
Chapter 1--Title
... Primary and secondary amines can form hydrogen bonds to each other and water Tertiary amines cannot form hydrogen bonds to each other but can form hydrogen bonds to hydrogen bond donors such as water Tertiary amines have lower boiling points than primary or secondary amines of comparable molecula ...
... Primary and secondary amines can form hydrogen bonds to each other and water Tertiary amines cannot form hydrogen bonds to each other but can form hydrogen bonds to hydrogen bond donors such as water Tertiary amines have lower boiling points than primary or secondary amines of comparable molecula ...
Chapter 1--Title - Chemistry Workshop
... Primary and secondary amines can form hydrogen bonds to each other and water Tertiary amines cannot form hydrogen bonds to each other but can form hydrogen bonds to hydrogen bond donors such as water Tertiary amines have lower boiling points than primary or secondary amines of comparable molecula ...
... Primary and secondary amines can form hydrogen bonds to each other and water Tertiary amines cannot form hydrogen bonds to each other but can form hydrogen bonds to hydrogen bond donors such as water Tertiary amines have lower boiling points than primary or secondary amines of comparable molecula ...
reactions of alcohols with alkenes over an aluminum
... The ethers produced were identified by GLC-MS cracking patterns. Generally the yield of the tertiary alcohol, 2-methyl pentan-2-ol, was between 0.8 and 1.2 mole, which is less than that which could have been produced if all of the interlayer water originally in the clay had been consumed (4.2 mmole) ...
... The ethers produced were identified by GLC-MS cracking patterns. Generally the yield of the tertiary alcohol, 2-methyl pentan-2-ol, was between 0.8 and 1.2 mole, which is less than that which could have been produced if all of the interlayer water originally in the clay had been consumed (4.2 mmole) ...
Wolff–Kishner reduction
The Wolff–Kishner reduction is a reaction used in organic chemistry to convert carbonyl functionalities into methylene groups. In the context of complex molecule synthesis, it is most frequently employed to remove a carbonyl group after it has served its synthetic purpose of activating an intermediate in a preceding step. As such, there is no obvious retron for this reaction. Originally reported by Nikolai Kischner in 1911 and Ludwig Wolff in 1912, it has been applied to the total synthesis of scopadulcic acid B, aspidospermidine and dysidiolide.In general, the reaction mechanism first involves the in situ generation of a hydrazone by condensation of hydrazine with the ketone or aldehyde substrate. Sometimes it is however advantageous to use a pre-formed hydrazone as substrate (see modifications). The hydrazone is deprotonated by alkoxide base followed by a concerted, rate-determining step in which a diimide anion is formed. Collapse of this alkyldiimde with loss of N2 leads to formation of an alkylanion which can be protonated by solvent to give the desired product.Because the Wolff–Kishner reduction requires highly basic conditions, it is unsuitable for base-sensitive substrates. However, this method can be superior over the related Clemmensen reduction for acid-sensitive compounds such as pyrroles and for high-molecular weight compounds.