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Small pox
Small pox

... are not within acceptable limits, your physician will either reduce your dose or discontinue therapy. Hydration with normal saline and administration of oral probenecid help to reduce the risk of kidney toxicity. Cidofovir can also cause a fall in the number of white blood cells. This can increase y ...
Emerging Zoonoses
Emerging Zoonoses

... • Need for a scientific bridge between various disciplines: zoology, ecology, ornithology, geography, veterinary and human medicines…as illustrated by the early “West Nile fiasco” bird disease or human disease?…Which agency is in charge? • Interface between Public Health and Veterinary Public Health ...
Infectious Disease and Personal Protection Techniques for Infection
Infectious Disease and Personal Protection Techniques for Infection

... gingivostomatitis. Recurrent infections in the form of herpes labialis can also occur. A herpes simplex virus infection of the fingers (herpetic whitlow) is usually caused by direct contact with a herpetic lesion or infected saliva (Malik 2008). Transmission occurs by direct contact of the affected ...
Slide 1
Slide 1

... how many people does an infectious case come into contact with) and the transmission process (i.e. of those ...
2014 Annual Summary of Reportable Infectious Diseases for
2014 Annual Summary of Reportable Infectious Diseases for

... Cryptosporidium parvum, protozoan parasites that produce oocysts. The oocysts are highly infective for humans and most animals. The oocysts are also resistant to chlorine and other disinfectants. Mode of Transmission: Fecal-oral route, including person-to-person, animal-to-person, waterborne and foo ...
PDF
PDF

... of the thymidine kinase and vaccinia growth factor genes, we noticed that confluent monolayers of SCCF1 cat squamous carcinoma cells were not destroyed even after prolonged infection. Interestingly, although SCCF1 cells were not killed, they continuously secreted virus into the cell culture supernat ...
Novel, Real-Time Cell Analysis for Measuring Viral
Novel, Real-Time Cell Analysis for Measuring Viral

... new format to measure the cytopathic effect (CPE) of the 2009 influenza A (H1N1) virus and the efficacy of neutralizing antibodies in human sera to this virus. The real-time dynamic monitoring of CPE was performed on MDCK cell cultures infected with the H1N1 virus, ranging from 5.506102 to 5.506107 ...
Croup Fact Sheet
Croup Fact Sheet

... secretions of infected persons or contact with contaminated surfaces or objects. Infection can occur through the eyes, mouth, or nose, and possibly through the breathing in droplets generated by a sneeze or cough. HPIVs can remain infectious in the air for over an hour. 4. Is there a vaccine? - No v ...
“for their discovery of human immunodeficiency virus” “for his
“for their discovery of human immunodeficiency virus” “for his

... just two years after the first reports of cases of what we now know as AIDS. An infective agent was suspected by many to cause the disease, and BarréSinoussi and Montagnier decided to test whether it might be a so-called retrovirus. Retroviruses are relatively uncommon among the viruses that infect ...
Hantavirus Pulmonary Syndrome
Hantavirus Pulmonary Syndrome

... usually sporadic (14), although outbreaks have been reported (9, 13). Most cases of HPS occur in spring and summer (5). The first outbreak of HPS identified in North America was in 1993 in the United States of America (9). Since then, more than 2,000 cases of HPS caused by different strains have occ ...
Infectious Diseases in New Mexico
Infectious Diseases in New Mexico

... Influenza (flu) is an illness caused by a virus which spreads through droplets in the air when an infected person coughs, sneezes, or speaks.1 The virus attacks the respiratory system, often resulting in a rapid onset of fever, aching muscles, and nasal congestion. A short incubation period of 2 to ...
Viruses, Prions and Viroids Infectious Agents of Animals
Viruses, Prions and Viroids Infectious Agents of Animals

... with Their Host  Persistent infections  Latent infections (presence of virus not always detectable)  Infection is followed by symptomless period then ...
Autoimmune computer virus
Autoimmune computer virus

... host and actually cause damage are known as autoimmune diseases. Computer autoimmune disorders parallel their biological counterparts. Recently, a warning (defense mechanism used by computer users) turned out to be a not-so-harmless hoax. The hoax warning stated that certain files were infected by a ...
College of Medicine Microbiology
College of Medicine Microbiology

... are very small and have vary widely range in size , ranged from 20300nm in diameter. The smallest virus is polio virus has a diameter about 20nm. The largest are poxvirus (300nm). Most cells (animals, plants, microorganisms)are measured by micrometer (µm), whereas cellular parts and viruses are meas ...
Ruling Out Novel H1N1 Influenza Virus Infection with Direct
Ruling Out Novel H1N1 Influenza Virus Infection with Direct

... (1) Simulfluor influenza A/B (Chemicon/Millipore) and (2) D3 DuetTM DFA RSV/Respiratory Virus Screening Kit (RVP; Diagnostic Hybrids), which tests for influenza A and B viruses, adenovirus, respiratory syncytial virus, and parainfluenza virus. The Simulfluor kit was used for influenza testing unless ...
Interference of reovirus strains occurs between the stages of
Interference of reovirus strains occurs between the stages of

... M2 ssRNA itself; however, there is no clear evidence for the interaction of ~tl protein with virus ssRNAs either alone or in complex with other reovirus proteins (e.g. non-structural) or host proteins. The fact that delaying infection with the interfering wild-type T3D (in the mixed infection with T ...
A CARRIER STATE OF MUMPS VIRUS IN HUMAN CONJUNCTIVA
A CARRIER STATE OF MUMPS VIRUS IN HUMAN CONJUNCTIVA

... Dunai strain of mumps virus into cultures of actively growing human conjuncfiva cells, and that virus from cartier cultures would readily establish a carrier relationship when transferred to new cultures of conjuncfiva cells. Study was then concentrated on the original carrier cultures, designated C ...
presentation
presentation

... efficacious compared to higher doses – For GT3: 50 mg QD dose is predicted to be similar to placebo in terms of viral load decline ...
case history 5
case history 5

... Respiratory Tract Infection Faculty Copy – Page 12 The net result of these effect, is that on entry into the respiratory tract, the viruses cause cell damage, especially in the respiratory epithelium, which elicits an acute inflammatory response and impairs mechanical and cellular host responses. T ...
Heartland Virus–Associated Death in Tennessee
Heartland Virus–Associated Death in Tennessee

... older male farmers who presented with fever, leukopenia, and thrombocytopenia. However, the original 2 HRTV case-patients were younger (57 and 67 years), had higher platelet count nadirs at 34–37 × 103 platelets/µL, did not require transfusions, and survived without hemorrhagic manifestations or mul ...
Exploratory Space-Time Analyses of Rift Valley Fever in
Exploratory Space-Time Analyses of Rift Valley Fever in

... [41,44,45]. These vector-borne transmission patterns share some similarities with the initial and localised contagious processes observed during RVF epidemics in 2010 and 2011, but our study detected the presence of an additional spatiotemporal process, with RVF potentially spreading to distances up ...
Safety and immunogenicity of myxoma virus as a new viral vector for
Safety and immunogenicity of myxoma virus as a new viral vector for

... infection, fibroblasts might be among the main cell type initially infected by the virus at the primary site of inoculation before it possibly disseminates to other peripheral tissues. Thus, we investigated the infection of primary ovine dermal fibroblasts. We infected both RK13 and ovine primary fi ...
fmd with viaa test incl.
fmd with viaa test incl.

... Culicoides and mosquito insect cell lines. Blood samples collected in an appropriate anticoagulant can be used undiluted as the inoculum. After 15–60 minutes of adsorption at ambient temperature or at 37°C, the cell cultures are washed and maintenance medium is added. Alternatively and more commonly ...
Viruses
Viruses

... 2. Infection A) Diseases range from asymptomatic to deadly B) Common symptoms include rashes, fever, muscle aches, respiratory involvement and swollen lymph nodes C) Infection can start at the portal of entry or the virus may enter the bloodstream and cause infections elsewhere D) Some may cause the ...
Reduction of Otherwise Remarkably Stable Virus-specific
Reduction of Otherwise Remarkably Stable Virus-specific

... Experimental analyses of the acute cytotoxic T lymphocyte (CTL) response to viruses have focused on studying these infections in immunologically naive hosts. In the natural environment, however, viral C T L responses occur in hosts that are already immune to other infectious agents. To address which ...
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Ebola virus disease



Ebola virus disease (EVD; also Ebola hemorrhagic fever, or EHF), or simply Ebola, is a disease of humans and other primates caused by ebolaviruses. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. Then, vomiting, diarrhea and rash usually follow, along with decreased function of the liver and kidneys. At this time some people begin to bleed both internally and externally. The disease has a high risk of death, killing between 25 and 90 percent of those infected, with an average of about 50 percent. This is often due to low blood pressure from fluid loss, and typically follows six to sixteen days after symptoms appear.The virus spreads by direct contact with body fluids, such as blood, of an infected human or other animals. This may also occur through contact with an item recently contaminated with bodily fluids. Spread of the disease through the air between primates, including humans, has not been documented in either laboratory or natural conditions. Semen or breast milk of a person after recovery from EVD may still carry the virus for several weeks to months. Fruit bats are believed to be the normal carrier in nature, able to spread the virus without being affected by it. Other diseases such as malaria, cholera, typhoid fever, meningitis and other viral hemorrhagic fevers may resemble EVD. Blood samples are tested for viral RNA, viral antibodies or for the virus itself to confirm the diagnosis.Control of outbreaks requires coordinated medical services, alongside a certain level of community engagement. The medical services include rapid detection of cases of disease, contact tracing of those who have come into contact with infected individuals, quick access to laboratory services, proper healthcare for those who are infected, and proper disposal of the dead through cremation or burial. Samples of body fluids and tissues from people with the disease should be handled with special caution. Prevention includes limiting the spread of disease from infected animals to humans. This may be done by handling potentially infected bush meat only while wearing protective clothing and by thoroughly cooking it before eating it. It also includes wearing proper protective clothing and washing hands when around a person with the disease. No specific treatment or vaccine for the virus is available, although a number of potential treatments are being studied. Supportive efforts, however, improve outcomes. This includes either oral rehydration therapy (drinking slightly sweetened and salty water) or giving intravenous fluids as well as treating symptoms.The disease was first identified in 1976 in two simultaneous outbreaks, one in Nzara, and the other in Yambuku, a village near the Ebola River from which the disease takes its name. EVD outbreaks occur intermittently in tropical regions of sub-Saharan Africa. Between 1976 and 2013, the World Health Organization reports a total of 24 outbreaks involving 1,716 cases. The largest outbreak is the ongoing epidemic in West Africa, still affecting Guinea and Sierra Leone. {{#section:Ebola virus epidemic in West Africa|casesasof}}, this outbreak has {{#section:Ebola virus epidemic in West Africa|cases}} reported cases resulting in {{#section:Ebola virus epidemic in West Africa|deaths}} deaths.{{#section:Ebola virus epidemic in West Africa|caserefs}}
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