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... enough to fulfill the switching role we seek. As a result, neuromodulation is not generally considered to be a candidate mechanism for rapid and precise switching of complex neural circuits and responses. Nevertheless, it is good to keep in mind that this standard wisdom may be wrong (see Sherman an ...
... enough to fulfill the switching role we seek. As a result, neuromodulation is not generally considered to be a candidate mechanism for rapid and precise switching of complex neural circuits and responses. Nevertheless, it is good to keep in mind that this standard wisdom may be wrong (see Sherman an ...
TINS04
... One notable aspect of dyslexia that puzzles theorists and causes much confusion is the variety of symptoms that are consistently associated with it: problems with reading, of course, but also problems with phonology (the mental representation and processing of speech sounds), sensory difficulties in ...
... One notable aspect of dyslexia that puzzles theorists and causes much confusion is the variety of symptoms that are consistently associated with it: problems with reading, of course, but also problems with phonology (the mental representation and processing of speech sounds), sensory difficulties in ...
Temporal and spatial neural dynamics in the perception of basic
... sadness and happiness may involve a slower unfolding over time than that of fear or disgust (Fredrickson, 1998; Baumeister et al., 2001). Aside from its theoretical relevance, including the time element in our current understanding of emotions can also yield new discoveries about how emotions are re ...
... sadness and happiness may involve a slower unfolding over time than that of fear or disgust (Fredrickson, 1998; Baumeister et al., 2001). Aside from its theoretical relevance, including the time element in our current understanding of emotions can also yield new discoveries about how emotions are re ...
University of Groningen The hearing brain in males and
... local brain activity. The most direct, but also invasive, way of studying brain activity in the living brain is direct single cell recording, i.e. an electrode is inserted directly into the brain. This technique is restricted to animal studies because of the invasiveness. This technique gives detail ...
... local brain activity. The most direct, but also invasive, way of studying brain activity in the living brain is direct single cell recording, i.e. an electrode is inserted directly into the brain. This technique is restricted to animal studies because of the invasiveness. This technique gives detail ...
Matching mind to world and vice versa: Functional dissociations
... With the aim of understanding how different mental or intentional states are processed in the brain, the present functional magnetic resonance imaging (fMRI) study examined the brain correlates during the ascription of belief intentional states relative to desire intentional states as well as the ef ...
... With the aim of understanding how different mental or intentional states are processed in the brain, the present functional magnetic resonance imaging (fMRI) study examined the brain correlates during the ascription of belief intentional states relative to desire intentional states as well as the ef ...
Implications of Altered Brain Ganglioside Profiles in Amyotrophic
... is not restricted td motor cortex but is found also in other regions of the brain. I would like to describe the manner in which these studies were begun and then extended since this may have important implications for further developments. This work was undertaken in 1975 principally for the reason ...
... is not restricted td motor cortex but is found also in other regions of the brain. I would like to describe the manner in which these studies were begun and then extended since this may have important implications for further developments. This work was undertaken in 1975 principally for the reason ...
Motor Cortical Networks for Skilled Movements Have Reaching
... Spike trains from eight groups of simultaneously recorded cells (95 neurons in total) were acquired. A point process generalized linear model (GLM) was developed to assess simultaneously recorded cells for functional connectivity during reaching attempts where unforced errors or no errors were made. ...
... Spike trains from eight groups of simultaneously recorded cells (95 neurons in total) were acquired. A point process generalized linear model (GLM) was developed to assess simultaneously recorded cells for functional connectivity during reaching attempts where unforced errors or no errors were made. ...
Communication as an emergent metaphor for neuronal operation
... Biological evidence. Recent advances in neuroscience provide us with evidence that neurons are much more complex than previously thought [19]. In particular it has been hypothesised that neurons can select input depending on its spatial location on dendritic tree or temporal structure [19,20,21]. So ...
... Biological evidence. Recent advances in neuroscience provide us with evidence that neurons are much more complex than previously thought [19]. In particular it has been hypothesised that neurons can select input depending on its spatial location on dendritic tree or temporal structure [19,20,21]. So ...
Surface-view connectivity patterns of area 18 in cats
... identify the valid subdivisions of neocortex in numerous species, and opinions have varied considerably. Nevertheless, there has been much progress. There is also a general acceptance that each different method of subdividing cortex has its own strengths and weaknesses, and that the most reliable ap ...
... identify the valid subdivisions of neocortex in numerous species, and opinions have varied considerably. Nevertheless, there has been much progress. There is also a general acceptance that each different method of subdividing cortex has its own strengths and weaknesses, and that the most reliable ap ...
Chapter 12 PowerPoint - Hillsborough Community College
... • Electroencephalogram (EEG) records electrical activity that accompanies brain function – Used for diagnosing epilepsy and sleep disorders – Localizes lesions, tumors, infarcts, infections, abscesses – Used in research and also to determine brain death – Electrodes placed on scalp measure electrica ...
... • Electroencephalogram (EEG) records electrical activity that accompanies brain function – Used for diagnosing epilepsy and sleep disorders – Localizes lesions, tumors, infarcts, infections, abscesses – Used in research and also to determine brain death – Electrodes placed on scalp measure electrica ...
Az alvás és ébrenlét, gondolkodás, morális és emocionális
... Lesions of the posterior hypothalamic area may cause hypersomnolence or even coma. This area contains the tuberomammillary nucleus, housing hundreds of histaminergic neurons, which project widely to the gray matter of the brain and spinal cord. Histaminergic fibers destined for the cerebral cortex. ...
... Lesions of the posterior hypothalamic area may cause hypersomnolence or even coma. This area contains the tuberomammillary nucleus, housing hundreds of histaminergic neurons, which project widely to the gray matter of the brain and spinal cord. Histaminergic fibers destined for the cerebral cortex. ...
General Cortical and Special Prefrontal Connections: Principles
... computational analysis of connections using an extensive database (Goulas et al. 2014). The structural model thus predicts laminar patterns of connections, constrained by a rule based on the magnitude of the structural similarity/dissimilarity between linked areas (Figure 2). In contrast, hierarchic ...
... computational analysis of connections using an extensive database (Goulas et al. 2014). The structural model thus predicts laminar patterns of connections, constrained by a rule based on the magnitude of the structural similarity/dissimilarity between linked areas (Figure 2). In contrast, hierarchic ...
The Relationship Between Synchronization Among Neuronal
... random noisy input was provided to all units in one of the two areas (area 1). In some simulations, the mean interarea delay was increased to 8 ms to mimic a greater separation between the areas. In other simulations, excitatory NMDA synaptic channels were incorporated. These NMDA channels were used ...
... random noisy input was provided to all units in one of the two areas (area 1). In some simulations, the mean interarea delay was increased to 8 ms to mimic a greater separation between the areas. In other simulations, excitatory NMDA synaptic channels were incorporated. These NMDA channels were used ...
Forward Prediction in the Posterior Parietal Cortex and Dynamic
... from motion-sensitive extrastriate areas (Felleman and Van Essen, 1991). Its activity is modulated by world-centered gain fields (Snyder et al., 1998) and other top-down inputs from the prefrontal cortex (Crowe et al., 2013), hippocampus and cerebellum (Clower et al., 2001). Consequently, it is idea ...
... from motion-sensitive extrastriate areas (Felleman and Van Essen, 1991). Its activity is modulated by world-centered gain fields (Snyder et al., 1998) and other top-down inputs from the prefrontal cortex (Crowe et al., 2013), hippocampus and cerebellum (Clower et al., 2001). Consequently, it is idea ...
View CV as a PDF - Cedars
... My current research focus combines neuroscience and regenerative medicine in order to understand mechanisms of disease and neurological disorders such as ALS and traumatic brain injury with the goal of developing therapeutic treatments. ...
... My current research focus combines neuroscience and regenerative medicine in order to understand mechanisms of disease and neurological disorders such as ALS and traumatic brain injury with the goal of developing therapeutic treatments. ...
The columnar organization of the neocortex
... 1989; Cepko et al., 1990; Luskin, 1996). The virus particles are injected into the ventricles of the living rat embryo where they are incorporated into the DNA of dividing cells, and appear undiluted in 50% of their descendants. They can be identified at any later time by histochemical methods. Lusk ...
... 1989; Cepko et al., 1990; Luskin, 1996). The virus particles are injected into the ventricles of the living rat embryo where they are incorporated into the DNA of dividing cells, and appear undiluted in 50% of their descendants. They can be identified at any later time by histochemical methods. Lusk ...
~ Pergamon
... *Department of Behavioral Neuroscience, Boston University School of Medicine, Boston, MA tDepartment of Health Science, Boston University, 635 Commonwealth Avenue, #431, Boston MA, 02215, and Department of Anatomy and Neurobiology, Boston University School of Medicine, and New England Regional Prima ...
... *Department of Behavioral Neuroscience, Boston University School of Medicine, Boston, MA tDepartment of Health Science, Boston University, 635 Commonwealth Avenue, #431, Boston MA, 02215, and Department of Anatomy and Neurobiology, Boston University School of Medicine, and New England Regional Prima ...
ATP-Sensitive K+ Channels in the Brain: Sensors of
... energy-demanding seizure during metabolic stress, the ATPsensitive K+ (KATP) channel, the molecule that controls membrane potentials by sensing intracellular ATP levels, may play a pivotal role. In this brief review, recent progress in accord with this hypothesis is discussed, together with other vi ...
... energy-demanding seizure during metabolic stress, the ATPsensitive K+ (KATP) channel, the molecule that controls membrane potentials by sensing intracellular ATP levels, may play a pivotal role. In this brief review, recent progress in accord with this hypothesis is discussed, together with other vi ...
Chapter 15 - Las Positas College
... that provide a stable internal environment for you. Some of the important visceral functions under the regulation of the ANS are maintenance of heart rate and blood pressure, digestion, and urination. Anatomically, the ANS is described as a motor (efferent) pathway made up of two neurons, and Chapte ...
... that provide a stable internal environment for you. Some of the important visceral functions under the regulation of the ANS are maintenance of heart rate and blood pressure, digestion, and urination. Anatomically, the ANS is described as a motor (efferent) pathway made up of two neurons, and Chapte ...
From sensorimotor learning to memory cells in prefrontal and
... Fig. 2 e Brain areas, model architecture and connectivity. (A)e(B) Sets of cortical areas, which were imitated by the network’s area structure and long-distance connectivity. Sensory (different shades of blue) and motor (shades of red) areas relevant for learning the associations (A) between articul ...
... Fig. 2 e Brain areas, model architecture and connectivity. (A)e(B) Sets of cortical areas, which were imitated by the network’s area structure and long-distance connectivity. Sensory (different shades of blue) and motor (shades of red) areas relevant for learning the associations (A) between articul ...
Behavioural Brain Research Multisensory contributions to the
... involved. Computational models explicitly link neurophysiological and behavioural experimental observations by the construction and simulation of microscopic models based on local networks with large numbers of neurons and synapses that lead to the desired global behaviour of the whole system. Bioph ...
... involved. Computational models explicitly link neurophysiological and behavioural experimental observations by the construction and simulation of microscopic models based on local networks with large numbers of neurons and synapses that lead to the desired global behaviour of the whole system. Bioph ...
11. The Evolution of Language Systems in the Human Brain
... morphological or syntactic processing have been identified; see below). One major reason for this may be the difficulty of translating highly abstract linguistic formalisms into concrete anatomical predictions. At least superficially, language appears to be generated according to symbolic principles ...
... morphological or syntactic processing have been identified; see below). One major reason for this may be the difficulty of translating highly abstract linguistic formalisms into concrete anatomical predictions. At least superficially, language appears to be generated according to symbolic principles ...
Resting-State Connectivity Predictors of Response to
... monitoring of emotional salience (Ressler and Mayberg, 2007; Seminowicz et al, 2004); (2) the subcortical brain regions that process affective stimuli (Kumar et al, 2008; Pizzagalli et al, 2009) and that modulate emotional memory formation and retrieval (Dillon et al, 2013); and (3) the coordinated ...
... monitoring of emotional salience (Ressler and Mayberg, 2007; Seminowicz et al, 2004); (2) the subcortical brain regions that process affective stimuli (Kumar et al, 2008; Pizzagalli et al, 2009) and that modulate emotional memory formation and retrieval (Dillon et al, 2013); and (3) the coordinated ...
A genome-scale, constraint-based approach to systems biology of
... a cell, underscored by its involvement in integral cellular processes. It is an interconnected system of chemical transformations necessary to sustain various cellular functions and includes the degradation of molecules for energy production and the assembly of essential cellular constituents. The c ...
... a cell, underscored by its involvement in integral cellular processes. It is an interconnected system of chemical transformations necessary to sustain various cellular functions and includes the degradation of molecules for energy production and the assembly of essential cellular constituents. The c ...
The Red Nucleus: Past, Present, and Future
... levels of connectivity of the RN in terrestrial vertebrates to development of the cerebellum. A primitive level of RN organization is present in amphibians with only one cerebellar nucleus and no evidence of a rubro-olivary projection. Limbed reptiles demonstrate a more advanced level of organizatio ...
... levels of connectivity of the RN in terrestrial vertebrates to development of the cerebellum. A primitive level of RN organization is present in amphibians with only one cerebellar nucleus and no evidence of a rubro-olivary projection. Limbed reptiles demonstrate a more advanced level of organizatio ...
Connectome
![](https://commons.wikimedia.org/wiki/Special:FilePath/White_Matter_Connections_Obtained_with_MRI_Tractography.png?width=300)
A connectome is a comprehensive map of neural connections in the brain, and may be thought of as its ""wiring diagram"". More broadly, a connectome would include the mapping of all neural connections within an organism's nervous system.The production and study of connectomes, known as connectomics, may range in scale from a detailed map of the full set of neurons and synapses within part or all of the nervous system of an organism to a macro scale description of the functional and structural connectivity between all cortical areas and subcortical structures. The term ""connectome"" is used primarily in scientific efforts to capture, map, and understand the organization of neural interactions within the brain.Research has successfully constructed the full connectome of one animal: the roundworm C. elegans (White et al., 1986, Varshney et al., 2011). Partial connectomes of a mouse retina and mouse primary visual cortex have also been successfully constructed. Bock et al.'s complete 12TB data set is publicly available at Open Connectome Project.The ultimate goal of connectomics is to map the human brain. This effort is pursued by the Human Connectome Project, sponsored by the National Institutes of Health, whose focus is to build a network map of the human brain in healthy, living adults.