Food and Drug Interaction: Quinolones
... teaching aid and may not provide all the information you need. ...
... teaching aid and may not provide all the information you need. ...
Lecture 16 Pharmacokinetics - Cal State LA
... 2. Metabolic stability (continued) Drug - drug interaction examples: •Antibiotics can act as P450 inhibitors; slows the metabolism of other drugs by these enzymes. •Phenobarbitone (barbituate) stimulates the P450 enzymes, accelerating the metabolism of Warfarin (anticoagulant), making it less effec ...
... 2. Metabolic stability (continued) Drug - drug interaction examples: •Antibiotics can act as P450 inhibitors; slows the metabolism of other drugs by these enzymes. •Phenobarbitone (barbituate) stimulates the P450 enzymes, accelerating the metabolism of Warfarin (anticoagulant), making it less effec ...
What do you know about Drugs
... How are Prescription Drugs abused? • It depends—some people take other people’s drugs for their intended purposes (to relieve pain, to stay awake, or to fall asleep). • Others take them to get high, often at larger doses than prescribed, or by a different route of administration. ...
... How are Prescription Drugs abused? • It depends—some people take other people’s drugs for their intended purposes (to relieve pain, to stay awake, or to fall asleep). • Others take them to get high, often at larger doses than prescribed, or by a different route of administration. ...
Phase I Issues for Novel TB Drugs
... drug in absence and presence of interacting drug(s) • Appropriate design depends on several factors: – PK characteristics of TB drug and its metabolites – Safety margin of TB drug – Nature and characterization of the suspected interaction for TB drug • Selection of Interacting drug(s) – Known CYP450 ...
... drug in absence and presence of interacting drug(s) • Appropriate design depends on several factors: – PK characteristics of TB drug and its metabolites – Safety margin of TB drug – Nature and characterization of the suspected interaction for TB drug • Selection of Interacting drug(s) – Known CYP450 ...
Medications, Herbal Supplements & Diet
... • Used for less serious conditions • May cause adverse effects, especially if used inappropriately ...
... • Used for less serious conditions • May cause adverse effects, especially if used inappropriately ...
K2/Spice, Bath Salts, and other drugs, Vinnie Happ
... - MDMA, or 3,4-methylenedioxy-N-methylamphetamine, was patented by Merck pharmaceuticals in 1914 - did not make much news until the 1970s, when psychotherapists began giving it to patients to get them to open up. -arrived at New York nightclubs in the late 1980s, and by the early ’90s - Ecstasy was ...
... - MDMA, or 3,4-methylenedioxy-N-methylamphetamine, was patented by Merck pharmaceuticals in 1914 - did not make much news until the 1970s, when psychotherapists began giving it to patients to get them to open up. -arrived at New York nightclubs in the late 1980s, and by the early ’90s - Ecstasy was ...
Power Point
... Lifestyle modifications Initial drug choices Not at goal BP- combination drug therapy ...
... Lifestyle modifications Initial drug choices Not at goal BP- combination drug therapy ...
Section 2: Drugs as Medicines
... disease that cases a fever should never take aspirin. The combination of aspirin and theses disease can cause or increase the risk of dangerous ...
... disease that cases a fever should never take aspirin. The combination of aspirin and theses disease can cause or increase the risk of dangerous ...
12598516_ADF DRUG CONTROL.short
... drug control and currently has 1.3 million drug offenders in prison, the 20-year long ‘war on drugs’ [started by Pres. Reagan in the 1980s] has had little demonstrable effect. The USA has one of the highest youth use prevalence rates in the world. ...
... drug control and currently has 1.3 million drug offenders in prison, the 20-year long ‘war on drugs’ [started by Pres. Reagan in the 1980s] has had little demonstrable effect. The USA has one of the highest youth use prevalence rates in the world. ...
Part 9: Drugs Affecting the GIT. DRUGS USED TO TREAT
... The granules of pantoprazole capsules may be given via NG tubes, but the NG tube must be at least 16 g or the tube may become clogged Capsule contents may be opened and mixed with apple juice, but do not chew or crush delayedrelease granules Proton pump inhibitors often work best when taken 30 ...
... The granules of pantoprazole capsules may be given via NG tubes, but the NG tube must be at least 16 g or the tube may become clogged Capsule contents may be opened and mixed with apple juice, but do not chew or crush delayedrelease granules Proton pump inhibitors often work best when taken 30 ...
Click here for Illegal Drugs PowerPoint Presentation
... CHEMICALLY SIMILAR TO BUT NOT EXACTLY LIKE THE DRUGS THEY ARE IMITATING. ...
... CHEMICALLY SIMILAR TO BUT NOT EXACTLY LIKE THE DRUGS THEY ARE IMITATING. ...
FROM THE BEGINNING TILL THE END OF FOSCARNET MIN 16:18
... Yes, in serious conditions mainly and in the conditions mentioned above. Can it kill the patient ? yes, these 3 groups. and these drugs aren't used in community, in order not to lose them and because of the cross resistance where we will lose the activity of all these drugs How to prophylact your bo ...
... Yes, in serious conditions mainly and in the conditions mentioned above. Can it kill the patient ? yes, these 3 groups. and these drugs aren't used in community, in order not to lose them and because of the cross resistance where we will lose the activity of all these drugs How to prophylact your bo ...
USMLE I
... efficacious than Drug Y. Efficacy is defined as the maximum effect that can be produced by a drug, regardless of dose. Drug X can only produce a 50% change in resistance, whereas Drug Y can produce a 75% change in resistance. Therefore, Drug X is less efficacious than Drug Y. ...
... efficacious than Drug Y. Efficacy is defined as the maximum effect that can be produced by a drug, regardless of dose. Drug X can only produce a 50% change in resistance, whereas Drug Y can produce a 75% change in resistance. Therefore, Drug X is less efficacious than Drug Y. ...
Drug metabolism and pharmacogenetics
... • Diet – Chargrilled foods and cruciferous vegetables induce CYP1A enzymes – Grapefruit juice inhibits CYP3A • Environment – Cigarette smoke induces P450 enzymes via Ahr dependent mechanism – Industrial workers exposed to some pesticides metabolize more rapidly ...
... • Diet – Chargrilled foods and cruciferous vegetables induce CYP1A enzymes – Grapefruit juice inhibits CYP3A • Environment – Cigarette smoke induces P450 enzymes via Ahr dependent mechanism – Industrial workers exposed to some pesticides metabolize more rapidly ...
What is in a name
... – Trade name misinterpreted for the # of tablets to give – Allergic reaction to one of the generic components (check for aspirin allergy) – Giving 2 #3’s instead of one #4 (doubles the dose of aspirin from 325mg to 650mg) ...
... – Trade name misinterpreted for the # of tablets to give – Allergic reaction to one of the generic components (check for aspirin allergy) – Giving 2 #3’s instead of one #4 (doubles the dose of aspirin from 325mg to 650mg) ...
GPAT - 2O1O BOOKLET CODE QUESTTON Test Paper Code: GPAT
... Streptomycin can NOT be given olally for treatment of tuberculosis because (A) it gets degraded in the GIT (B) it causes severe drarrhoea (C) it causes metallic taste in the mouth (Dt, it is not absorbed from the GIT ...
... Streptomycin can NOT be given olally for treatment of tuberculosis because (A) it gets degraded in the GIT (B) it causes severe drarrhoea (C) it causes metallic taste in the mouth (Dt, it is not absorbed from the GIT ...
Antidepressant drug interactions: evidence and clinical significance
... closely for adverse effects and drug interactions when co-prescribing fluvoxamine with most drugs and con sider using another SSRI that is less likely to interact. Fluoxetine and paroxetine are potent inhibitors of the hepatic isoenzyme CYP2D6 and thus can significantly increase the plasma concentr ...
... closely for adverse effects and drug interactions when co-prescribing fluvoxamine with most drugs and con sider using another SSRI that is less likely to interact. Fluoxetine and paroxetine are potent inhibitors of the hepatic isoenzyme CYP2D6 and thus can significantly increase the plasma concentr ...
CHOOSE THE SINGLE BEST ANSWER Matching. Match each of the
... Matching. Match each of the drugs listed below to one of the following treatments for their toxicity (A-D). Each treatment may be used once, more than once, or not at all. A. pyridoxine B. glucagon C. n-acetylcysteine D. calcium 8. _____ isoniazid 9. _____ verapamil 10._____ propanolol 11. If the o ...
... Matching. Match each of the drugs listed below to one of the following treatments for their toxicity (A-D). Each treatment may be used once, more than once, or not at all. A. pyridoxine B. glucagon C. n-acetylcysteine D. calcium 8. _____ isoniazid 9. _____ verapamil 10._____ propanolol 11. If the o ...
The Science of Recovery - AAP
... Acute intoxication results in activation and deactivation of regions connected to the DA system These regions are involved in ...
... Acute intoxication results in activation and deactivation of regions connected to the DA system These regions are involved in ...
Document
... A small # of drugs produce their physiological effect without interacting with receptors. Examples: Drugs that bind to enzymes interfere with the normal activity of the enzyme in one of 2 ways CompetitiveNon-competitiveDrugs can also bind to membrane transport proteins (competitively and non-compet ...
... A small # of drugs produce their physiological effect without interacting with receptors. Examples: Drugs that bind to enzymes interfere with the normal activity of the enzyme in one of 2 ways CompetitiveNon-competitiveDrugs can also bind to membrane transport proteins (competitively and non-compet ...
Toxicology
... Chemical forms that produce toxicity The parent drug is often the cause of toxic effects However, toxic effects may result from metabolites: For example: paracetamol 4th most common cause of death following self-poisoining in UK in 1989 ...
... Chemical forms that produce toxicity The parent drug is often the cause of toxic effects However, toxic effects may result from metabolites: For example: paracetamol 4th most common cause of death following self-poisoining in UK in 1989 ...
PATIENT`S NAME - McGraw-Hill
... § Take drug with food if it causes stomach upset. § Shake suspension well before using. WARNINGS & PRECAUTIONS! § Before taking this drug, tell your prescriber if you have liver disease. § Contact your prescriber if you experience wheezing, muscle spasms, or incoordination. § Avoid driving and other ...
... § Take drug with food if it causes stomach upset. § Shake suspension well before using. WARNINGS & PRECAUTIONS! § Before taking this drug, tell your prescriber if you have liver disease. § Contact your prescriber if you experience wheezing, muscle spasms, or incoordination. § Avoid driving and other ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.