ANTI-INFLAMMATORY ACTIVITY OF PLANTAGO EROSA WALL EXTRACTS IN RATS
... concentrations of 100 mg/kg, 200 mg/kg and 400 mg/kg produced 40.93%, 48.83% and 57.6% inhibition of exudate formation respectively. The standard drug aspirin produced 56.72% inhibition of exudate formation. The test drug 400 mg/kg is found to be more effective than the standard drug aspirin (100 mg ...
... concentrations of 100 mg/kg, 200 mg/kg and 400 mg/kg produced 40.93%, 48.83% and 57.6% inhibition of exudate formation respectively. The standard drug aspirin produced 56.72% inhibition of exudate formation. The test drug 400 mg/kg is found to be more effective than the standard drug aspirin (100 mg ...
PHARMACEUTICAL ASPECTS OF NICORANDIL
... other calcium antagonists affected atrioventricular nodal conduction and cardiac contractility. Moreover nicorandil does not produce an adverse reaction, even in combination with calcium antagonists or beta‐blocking agents25. Nicorandil delivery A drug delivery system is ...
... other calcium antagonists affected atrioventricular nodal conduction and cardiac contractility. Moreover nicorandil does not produce an adverse reaction, even in combination with calcium antagonists or beta‐blocking agents25. Nicorandil delivery A drug delivery system is ...
Document
... lives of many people who use them. Now, The Wall Street Journal has joined the fray. Health Journal columnist Melinda Beck revisited questions about whether statin drugs have cognitive side effects that leave users, particularly women, with muddled thinking and forgetfulness. “This drug makes wome ...
... lives of many people who use them. Now, The Wall Street Journal has joined the fray. Health Journal columnist Melinda Beck revisited questions about whether statin drugs have cognitive side effects that leave users, particularly women, with muddled thinking and forgetfulness. “This drug makes wome ...
... observation of the patients, aiming at regular intake of medications; and e) monitor and assessment of the information system and the impact of the measures adopted.26 Up to the beginning of that decade, in different introduction levels, the DOTS had been adopted in 155 countries, including Brazil. ...
Ecstasy - Introduction to Health
... and subsequently suffer burns on their fingers where they were holding the cigarette. In the same way they often burn holes in their clothing or in the furniture where they are sitting or lying. Those are a couple of the physical signs that might identify a heroin user. Some other signs include the ...
... and subsequently suffer burns on their fingers where they were holding the cigarette. In the same way they often burn holes in their clothing or in the furniture where they are sitting or lying. Those are a couple of the physical signs that might identify a heroin user. Some other signs include the ...
Oral suspension
... for Haemonchus longistipes, Ascaris spp., Monezia expansa and Fasciola hepatica, respectively. However, administration of the drug twice on the base of 2 weeks apart significantly raised the efficacy of the drug for clearance of the parasites from 92.5% to 100% in camels infected with various parasi ...
... for Haemonchus longistipes, Ascaris spp., Monezia expansa and Fasciola hepatica, respectively. However, administration of the drug twice on the base of 2 weeks apart significantly raised the efficacy of the drug for clearance of the parasites from 92.5% to 100% in camels infected with various parasi ...
C4: A-Z Drug Glossary and Acronyms
... The route of administration is important information to collect when taking a patient history. The way a drug (or drugs) enters the body will affect how quickly the drug has an effect, how the drug is metabolised and potential harms. Changing from one route to another may be a useful stepping stone ...
... The route of administration is important information to collect when taking a patient history. The way a drug (or drugs) enters the body will affect how quickly the drug has an effect, how the drug is metabolised and potential harms. Changing from one route to another may be a useful stepping stone ...
Muscle Relaxants
... released at the neuromuscular junction to bind with the ACh receptors on the postsynaptic membrane of the motor endplate They therefore block the action of ACh and prevent depolarisation. ...
... released at the neuromuscular junction to bind with the ACh receptors on the postsynaptic membrane of the motor endplate They therefore block the action of ACh and prevent depolarisation. ...
Anti-inflammatory & Pain
... • Have anti-inflammatory effects due to their inhibition of phospholipase • Raise the concentration of liver glycogen and increase blood glucose levels • Affect carbohydrate, protein, and fat ...
... • Have anti-inflammatory effects due to their inhibition of phospholipase • Raise the concentration of liver glycogen and increase blood glucose levels • Affect carbohydrate, protein, and fat ...
RisksofAnaesthesia2
... muscle relaxant given to modify the convulsion. If you suffer from muscle pains after ECT tell your anaesthetist and a drug may be given to try and prevent it. Confusion or memory loss This is common because of the effects of ECT. It may last a few days or weeks. Damage to teeth, lips or tongue Dama ...
... muscle relaxant given to modify the convulsion. If you suffer from muscle pains after ECT tell your anaesthetist and a drug may be given to try and prevent it. Confusion or memory loss This is common because of the effects of ECT. It may last a few days or weeks. Damage to teeth, lips or tongue Dama ...
What is mental life
... Major draining is through the inferior punctum – for maximum exposure you want to occlude the puctate to avoid loss of drug through the naso-lacrimal system. o Punctal occlusion = reduce systemic toxicity, avoid tasting the drops. Always occlude in pregnancy and when using -blockers! What if you th ...
... Major draining is through the inferior punctum – for maximum exposure you want to occlude the puctate to avoid loss of drug through the naso-lacrimal system. o Punctal occlusion = reduce systemic toxicity, avoid tasting the drops. Always occlude in pregnancy and when using -blockers! What if you th ...
Terminology and information on drugs
... listings, but selections. Street names are highly ambiguous, and should never be relied upon to characterize a given drug. 2. The sections on chemical constituents of cannabis plant, coca bush and opium poppy are not comprehensive listings, but focus on those substances which are of interest from a ...
... listings, but selections. Street names are highly ambiguous, and should never be relied upon to characterize a given drug. 2. The sections on chemical constituents of cannabis plant, coca bush and opium poppy are not comprehensive listings, but focus on those substances which are of interest from a ...
Dr. Jasti`s PowerPoint slides
... Daily dose: for infantile spasms, up to 150 mg/kg PO in 2 divided doses; for refractory complex partial seizures, 1,000 mg PO twice daily for patients 10–16 years old and 1,500 mg PO twice daily for those > 16 years of age or weighing > 60 kg ...
... Daily dose: for infantile spasms, up to 150 mg/kg PO in 2 divided doses; for refractory complex partial seizures, 1,000 mg PO twice daily for patients 10–16 years old and 1,500 mg PO twice daily for those > 16 years of age or weighing > 60 kg ...
Synergistic interactions of SQ109, a new
... antibiotics are studied for effects on bacterial growth inhibition at all possible concentrations, both alone and in combination, the nature of the interaction between the two antibiotics can be determined algebraically.9 The interaction between two antibiotics in combination can be described as Syn ...
... antibiotics are studied for effects on bacterial growth inhibition at all possible concentrations, both alone and in combination, the nature of the interaction between the two antibiotics can be determined algebraically.9 The interaction between two antibiotics in combination can be described as Syn ...
Introduction - Biomolecular Engineering Laboratory
... The War Production Board appointed A.L. Elder to coordinate the activities of penicillin producers to greatly increase the supply of penicillin in 1943 Commercial production of penicillin by a fermentation ...
... The War Production Board appointed A.L. Elder to coordinate the activities of penicillin producers to greatly increase the supply of penicillin in 1943 Commercial production of penicillin by a fermentation ...
Omnicare Diabetes Health Management Program
... practice guidelines, clinical studies or evidencebased review articles, and/or without either evidence of additional therapeutic benefit for the resident or clinical evidence that would warrant continued use of the medication” ...
... practice guidelines, clinical studies or evidencebased review articles, and/or without either evidence of additional therapeutic benefit for the resident or clinical evidence that would warrant continued use of the medication” ...
Slide 1
... two factories, by the end of 2008, and said its quarterly earnings grew but sales were little changed. In revealing an additional $1 billion in restructuring moves, Pfizer also said it does not expect sales to grow in 2007 and 2008, and that it might purchase up to $10 billion of its own stock. "The ...
... two factories, by the end of 2008, and said its quarterly earnings grew but sales were little changed. In revealing an additional $1 billion in restructuring moves, Pfizer also said it does not expect sales to grow in 2007 and 2008, and that it might purchase up to $10 billion of its own stock. "The ...
the use and abuse of drugs a handbook for health educators
... There is no precise definition of the term "drug" which will convey adequately the complex range and functions of therapeutic substances available to modern man. The origin of the word itself is unknown although variations of it appear in many modern languages. Generally speaking, any chemical subst ...
... There is no precise definition of the term "drug" which will convey adequately the complex range and functions of therapeutic substances available to modern man. The origin of the word itself is unknown although variations of it appear in many modern languages. Generally speaking, any chemical subst ...
Molecular and Pharmacological Review of Cannabimimetics factsheet
... designer drugs with cannabimimetic effects sold as spice and herbal blends. The detected naphthalen-1-yl-(1-pentylindol-3-yl)methanone JWH-0183 acts as a full agonist at the CB1 and CB2 receptor and produces effects similar to ∆9-tetrahydrocannabinol (THC). Due to the propagation by internet an incr ...
... designer drugs with cannabimimetic effects sold as spice and herbal blends. The detected naphthalen-1-yl-(1-pentylindol-3-yl)methanone JWH-0183 acts as a full agonist at the CB1 and CB2 receptor and produces effects similar to ∆9-tetrahydrocannabinol (THC). Due to the propagation by internet an incr ...
Lecture 05 - binding quant - Cal State LA
... While the occupancy theory simulates actual dose-response curves, (theoretically, KD = EC50), it does not account for agonists that do not produce the maximum effect. Modified occupancy theory: modified to separate the binding affinity from the intrinsic activity () of the compound. That is, a comp ...
... While the occupancy theory simulates actual dose-response curves, (theoretically, KD = EC50), it does not account for agonists that do not produce the maximum effect. Modified occupancy theory: modified to separate the binding affinity from the intrinsic activity () of the compound. That is, a comp ...
Mechanism of Action
... G3139 Antisense to Bcl-2 • G3139 is an 18-mer antisense oligonucleotide directed to the first 6 codons of the bcl-2 mRNA • G3139 downregulates bcl-2 mRNA /protein in a sequence specific and dose ...
... G3139 Antisense to Bcl-2 • G3139 is an 18-mer antisense oligonucleotide directed to the first 6 codons of the bcl-2 mRNA • G3139 downregulates bcl-2 mRNA /protein in a sequence specific and dose ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.